Both a theoretical text and a practical handbook, Vaccines for Veterinarians is the first of its kind to bring the basic science of animal vaccination and the practical details of vaccine use together in one single volume. From the first chapter on the history of vaccination and the triumph of rinderpest eradication to the last chapter on the rapidly emerging field of cancer vaccines, this book offers a truly comprehensive grounding in established and emerging vaccines for both major and minor species. Specific topics include viral vectored vaccines, DNA-plasmid vaccines, RNA vaccines, reverse vaccinology, the complexities of adjuvant use, vaccine failures and adverse events, vaccine production and regulation, robotic vaccination machines, contraceptive and production-enhancing vaccines, and so much more. At a time when resistance to human vaccination is receiving much publicity, this evidence-based book is the ideal counter to ill-informed speculation — serving as a timely reminder that vaccination is essential for the control of infectious diseases in animals. Well-respected and experienced veterinary author, Ian Tizard, provides expert guidance on the topic of vaccinations and immunology in veterinary medicine. Expert Consult site offers an online version of the book, making it easy to search the entire book electronically. The latest information on viral vectored vaccines keeps you up-to-date on the topic as well as the properties and relative advantages of currently used vectors in animal vaccines. Survey of vaccine responses covers the different mechanisms by which the immune system responds to different types of vaccines. Inclusion of the latest vaccine technologies discusses the advantages and disadvantages of DNA-plasmid vaccines, RNA vaccines, and more. Coverage of adverse events and hypersensitivities includes the best ways to treat them and report them. Coverage of passive immunization discusses the growing use of therapeutic monoclonal antibodies in veterinary medicine. Coverage of immunotherapy includes recent improvements and new products in both active and passive immunotherapy against animal cancers.
This volume of Advances in Veterinary Medicine, derived in part from the First Veterinary Vaccines and Diagnostic Conferences, deals with vaccines, an especially active area of veterinary research and controversy.
Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine that enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out. A new breed of vaccines is on the horizon that seeks to control fertility. Originally conceived to intercept a step in the reproductive process, they are conceptual models for developing approaches to regulate the body's internal processes.
Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.
In this compact, easy-to-understand volume, Clifton explains the very real risks involved every time a dog or cat gets a shot. The major veterinary associations now agree that vaccinations can trigger all sorts of maladies, from allergies to cancer. This guide encourages readers to learn about the risks and benefits of vaccinations. (Animals/Pets)
Over-vaccinating combined with stress, poor nutrition, and other factors is putting our companion animals at risk for serious diseases including auto-immune disorders, cancer or even death. In this well researched book, you will discover how typical vaccination protocols and environmental and genetic factors may be combining to turn your dog, cat, or horse into a ticking time-bomb of health problems, and how you can improve your pet's health and longevity. Bringing together research from around the world, Shock to the System explains the physiology of stress, the role of genetics and nutrition and the health risks to our companion animals from over-vaccination. It also suggests sound solutions to keeping your pet healthy.
Revised, updated 2nd edition brings fresh information and explains why the author feels you can protect your pets from disease homeopathically, without risking their lives by vaccinating them yearly.
Fish farming, in seawater and in freshwater, in cages, tanks or ponds, makes an ever-increasing and significant contribution to the production of aquatic food in many regions of the world. During the last few decades there has been significant progress and expansion in the aquaculture sector, characterized by intensified production and the exploitation of many new species. Aquaculture must be a sustainable bio-production, environmentally as well as economically. Disease prevention in order to reduce losses, and the use of antimicrobials is crucial in this perspective. Vaccination has, in a few years, become the most important method for disease prevention in aquaculture, and effective prophylaxis based on stimulation of the immune system of the fish is essential for further development of the industry. This book provides general information about disease prevention in fish by vaccination, as well as specific descriptions of the correct use of vaccines against the most important bacterial and viral infectious diseases of aquatic animals. The book is written by some of the world’s leading experts in the subject, drawn from many countries where aquaculture is a significant and expanding part of the economy. Fish Vaccination is an encyclopedia of fish vaccinology for every present and future aquaculturist. Professionals in the aquaculture sector, including fish veterinarians and fish biologists, within the industry, in scientific institutions and regulatory authorities will all find a huge wealth of commercially important knowledge within this book. Libraries in all universities where aquaculture, biological and veterinary sciences are studied and taught should have copies of this important book on their shelves.
This important book provides information on all canine and feline vaccines. It includes several personal stories of vaccine damage to family pets, as well as hundreds of studies documenting veterinary vaccine safety and efficacy problems.
Fenner's Veterinary, Virology, Fourth Edition, is the long awaited new edition of Veterinary Virology, 3e, which was published in 1999. Fully revised and updated by the new author team, part I presents the fundamental principles of virology related to animal infection and disease, and part II addresses the clinical features, pathogenesis, diagnosis, epidemiology and prevention of individual diseases. New to this Edition New author team - one main author to ensure that the book reads like an authored book but with the benefit of using experts to contribute to specific topics Text has been refocused - part I has been condensed and where appropriate incorporated into part II to make it more user friendly The number of figures have been increased and are now in full color Fully revised and updated to include the latest information in the field of veterinary virology Beautifully illustrated color figures throughout Organized and current information provided by an expert team of authors
Hardbound. Vaccination is widely recognised as one of the most efficient tools in public health, showing obvious cost-benefit advantages for all target populations involved.Vaccines in the veterinary field can contribute greatly to the welfare of domestic and wild animals and, indirectly, to environmental protection. The aim of animal vaccination will increasingly be to prevent dissemination of zoonoses (such as rabies, taeniosis, salmonellosis, etc.) rather than to protect the animal itself, especially when infection or infestation is not harmful to the reservoir (cysticercosis)At present there is insufficient overall understanding of some important aspects of veterinary vaccines. Literature on the subject exists, but often consists of either research communications or 'catalogue-type' descriptive works. This unique book fills a gap within the already available literature. The scope is broad and covers all aspects of vaccines and vaccination in the
Case Studies in Veterinary Immunology presents basic immunological concepts in the context of actual cases seen in clinics. It is intended for veterinary medicine students, interns, residents, and veterinarians, and serves as a valuable supplement and companion to a variety of core immunology textbooks and courses. The book includes cases describing primary immune system defects, secondary immune system defects, and hypersensitivity and autoimmune disorders, as well as dysproteinemias and lymphoid neoplasia. Drawing on the successful approach of Geha’s Case Studies in Immunology, each representative case is preceded by a discussion of the principles underlying that specific immunological mechanism. The case itself includes the presenting complaint (signalment), physical examination findings, pertinent diagnostic laboratory data, diagnosis, and treatment options. In those instances in which a specific disorder occurs in both animals and humans, the differences and similarities in the immunological mechanisms and manifestations of the disease are explored. End of case questions highlight important concepts and serve as a review aid for students. Details on standard vaccines and vaccination schedules, as well as descriptions of the types of assays used for evaluation of the immune system, are included as appendices.
Now in full color, this comprehensive reference provides current information on all parasites commonly encountered in veterinary medicine. This edition also covers organisms that infect poultry, laboratory animals, and exotic species.
The only complete resource on immunology for veterinary students and practitioners, Veterinary Immunology: An Introduction features a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts. Comprehensive coverage of vaccines and vaccine usage, allergies and allergic diseases, and autoimmunity and immunodeficiencies, prepare you for the multiple immunologic issues you will encounter in practice. A wealth of clinical examples clearly illustrate key concepts and offer practical strategies for diagnosing and treating immunologic disorders in the clinical setting. More than 500 full-color diagrams and illustrations visually demonstrate and clarify complex issues. Completely updated section on innate immunity includes new chapters on natural killer (NK) cells and systemic responses to infection to ensure you have the most up-to-date information. New information on genomics and molecular diagnostic techniques explores how the emerging field of genomics impacts disease resistance and immunology in general, as well as the diagnosis and treatment of immunological and infectious diseases. Updated content provides new information on well-recognized older diseases such as rheumatoid arthritis, systemic lupus, and inflammatory bowel disease, as well as current information on new diseases such as devil facial tumor disease and bovine neonatal pancytopenia. Expanded coverage brings you the latest knowledge on resistance to infection, such as vaccine usage, especially with respect to duration of immunity, the effects of key vitamins and lipids on immune responses, the effects of old age on immunity, and both antiviral and parasitic immunity. Diagnostic tests described throughout the text include a new section on the analysis of ELISA test data, as well as a brief summary of molecular diagnostic techniques. Coverage reflecting a significant change in the overall view of immunology provides you with the foundational knowledge needed to grasp the broad pattern of immunologic reactions and understand how the immune system functions as an interconnected network, rather than a series of independent pathways. New discussions of the critical importance of commensal bacteria and intestinal flora explain help you understand the importance of this normal flora with respect to antibacterial immunity, allergies, and autoimmunity, while at the same time providing a broader view of the animal body and its microflora as a "superorganism." A discussion of the importance of adipose tissue in immunity and inflammation addresses the epidemic of obesity in domestic pets and the extraordinary growth rates expected of domestic livestock. The section on inflammatory mechanisms has been divided into separate chapters focusing on the detection of invaders and the mediators of inflammation to incorporate the vast amount of new information on pattern recognition receptors and the ways in which they warn the body of microbial invasion.
Winner of Dog Writers Association of America's Dogwise Best Book AwardCanine Reproduction is a practical guide for veterinarians and an information source for breeders, kennel operators and others with a financial or humane interest in the breeding and maintenance of dogs.The book focuses on the veterinarian's responsibilities for managing the prob
I see a lot of dogs in my typical workday. Some sick, some healthy, many somewhere in between. I sometimes remember some details about them after their appointments, but there are a few dogs that are forever vividly etched in my memory. This is the case with Lucy, a 4 month old black Labrador mix adopted from a local rescue group. Lucy was my 9:15 appointment on an early fall Saturday morning, over eight years ago. It was a beautiful day, and I was looking forward to meeting a friend for lunch and then spending some time with my own dogs. Lucy had been with her owners a few weeks, and was a typical happy, active puppy. She had received her first vaccination (DAPP) four weeks ago while with her foster family. My physical examination revealed no abnormalities - she appeared completely healthy. So I administered her second DAPP vaccination, which happened to be exactly the same brand and formulation she had received a month ago. Before I could withdraw the needle from her skin, it was apparent that something was very wrong. Lucy stiffened, and then collapsed. I immediately began treatment for this vaccine reaction, and she responded initially. She had her first seizure half an hour later. Over the course of the morning, her seizures progressed, and she stopped responding to the intravenous fluids and drugs we administered. She died at 2:16 PM, just over five hours after she bounced into the hospital, a bright, happy puppy with a tennis ball in her mouth. My purpose in writing this book is to provide a straightforward explanation of what a vaccine is, how it works, and which are (and are not) needed for most dogs. This information is what I want to share with every new puppy owner at his or her first office call (and now that it is in book form I can!). As such, it is intended to be an understandable yet not "dumbed down" explanation of this important medical procedure for every concerned dog owner. You will notice scientific references sprinkled throughout the chapters, as well as in the References section. More technical information is available at the book website, www.VaccinesExplained.com for those interested. My basic vaccination schedule and "Best Practices" for vaccinating are also included. I sincerely hope this guide aids you in making informed vaccine choices for your dog.
This book provides essential worldwide reference information regarding rabies for public health officials, veterinarians, physicians, virologists, epidemiologists, infectious disease specialists, laboratory diagnosticians, and wildlife biologists. The book is divided into six main sections, covering topics such as the rabies virus, including antigenic and biochemical characteristics; pathogenesis, including the immune response to the infection, pathology, and latency; diagnostic techniques; rabies epidemiology in a variety of wild and domestic animals; rabies control, including vaccination of wild and domestic animals, as well as control on the international level; and finally a discussion of rabies in humans, local wound and serum treatment, and human post-exposure vaccination. Natural History of Rabies, First Edition has been the principal worldwide reference since 1975. The new Second Edition has been completely updated, providing current information on this historically deadly disease.
|Author||: Alejandro Schudel,Michel Lombard|
|Publisher||: S Karger Ag|
|Release Date||: 2004|
|Pages||: 513 pages|
This publication contains important and recent information as well as the history of successful controls of diseases, especially trans-boundary diseases but also parasitic infestations using traditional or marker vaccines. Chief Veterinary Officers, Animal Health regulatory officials, and veterinarians, cattle raising associations and consumer associations, will be helped by the information given in this publication. They will understand the complexity of the decision whether to use and select vaccines from the market or not. In this book, all the partners in the decision-making process for controlling diseases will find an aid for the elimination or eradication of pathogens.
Learn to effectively recognize, diagnose, and treat common internal medical conditions with this invaluable reference. Small Animal Internal Medicine, Fourth Edition, emphasizes practical diagnostic approaches and focuses on the clinically relevant aspects of patient medical management. Extensive color illustrations, boxes, and algorithms, plus new photographs, schematic representations, and updated tables, set this book apart. With its highly functional design and clear, expert voice, this text delivers the most relevant information for the internal medical challenges you’re most likely to face. Utilizes a problem-oriented approach, beginning with a discussion of clinical signs and diagnostic recommendations and techniques and moving on to therapeutic considerations and management Each contributor is a recognized expert in his or her respective specialty. Limited number of authors provides consistency. Clear, step-by-step procedural guidelines thoroughly describe each procedure. Cross-referencing throughout the book reduces redundancy and makes information easy to locate. Suggested readings at the end of each chapter alert you to the latest research findings. Comprehensive drug tables provide recommended dosages and indications. Purposefully written to enhance critical thinking and decision-making skills based on clinical findings. Hundreds of summary boxes and tables allow quick access to clinical signs, etiology, differential diagnoses, drugs, and treatment. Full-color format brings you accurate visual depictions of specific disorders, diseases, and procedures. Two new section editors bring a fresh perspective. Discussion of Immune-Mediated Disorders has been significantly expanded and made into its own section. Hundreds of new, full-color photographs and quick reference tables throughout Completely updated drug and treatment guidelines tables