Uveitis is inflammation of the middle layer of the eye, which is known as the uvea or uveal tract. It is a complex condition with a variety of causes and clinical manifestations, including injury, infection or an underlying condition. This 1200pp second edition brings ophthalmologists fully up to date with the latest developments in diagnosing and treating uveitis. Beginning with the basic principles of the disease, its diagnosis and management, the following sections discuss the treatment of numerous different infectious, non infectious, masquerade and autoimmune syndromes. Basic science, differential diagnosis, pathology and clinical management are discussed for each condition. Written by specialists from the Massachusetts Eye Research and Surgery Institution (MERSI) and John A Moran Eye Center in the USA, this comprehensive new edition includes 699 colour images and illustrations. Key points Comprehensive, second edition bringing ophthalmologists fully up to date with diagnosis and treatment of uveitis Discusses different uveitis syndromes – infectious, non infectious, masquerade and autoimmune Authored by US ophthalmic specialists Includes 699 full colour images and illustrations First edition published in 2001 by Saunders
Uveitis is a complex condition with a variety of causes and clinical manifestations. Certain types are extremely serious and can cause severe ocular morbidity if undetected and untreated. Even experienced ophthalmologists find it a difficult and frustrating condition, with the result that it is often misdiagnosed and mistreated. The wide array of diseases that can affect the uveal tract and the impact of immunological research – with resulting discovery of new uveitis entities – mean that clinicians managing patients with uveitis require a broad knowledge not only of relevant ophthalmology, but also immunology and general medicine. This book is designed to provide trainee and practising ophthalmologists with a user-friendly, up-to-date review of today’s body of knowledge about this difficult condition, and a practical guide to its diagnosis and management. From the foreword to the first edition, written by Jack Kanski: “(This book) presents a complex subject in a logical, systematic and easily digestible manner. I have learned much from reading it myself and some of my rather hazy ideas on the subject have been crystallised. Above all, the book contains lots of common sense. It is an excellent resumé of current knowledge which, I am sure, will be extremely useful to consultants, ophthalmologists in training, physicians, and all who deal with uveitis.” Key Points Extensively revised and updated to include latest management protocols and references High proportion of clinical photographs new to this edition, drawn from author’s personal collection and reproduced to highest quality Uveitis 2/e reflects unique experience of the author Nicholas Jones, a superb, world renowned clinician and inspiring teacher who created the Uveitis Clinic at the REH in Manchester, serving the Northwest of England and treating thousands of patients.
Intraocular inflammation is particularly difficult to diagnose and treat, often resembling a complex puzzle of patient history, symptoms, imaging, and laboratory test results. Clinical Cases in Uveitis: Differential Diagnosis and Management is a unique, case-based resource designed to help you navigate the range of challenging manifestations and presentations that often mimic other diseases. More than 90 real-world uveitis cases are presented in a highly templated, easy-to-follow format, along with step-by-step guidance on the right patient questions, assessment, differential diagnosis, testing, management, and follow-up care. Provides a variety of patient presentations and scenarios and unique clinical situations that mirror day-to-day practice. Covers current diagnostic imaging modalities, including optical coherence tomography (OCT), optical coherence tomography angiography, fluorescein angiography (FA), and indocyanine green angiography (ICG). Features diagnostic and management algorithms that assist in differential diagnosis and decision making for even the most complex cases, including those in which the patient does not improve as expected, prompting a reassessment of diagnosis and management. Contains approximately 250 high-quality images, including color anterior segment photographs, color fundus photographs, OCT images, and angiograms. Discusses distinguishing infectious from non-infectious inflammation; when and how to start systemic immunosuppressive therapy; diagnostic criteria and management of "white dot syndromes"; pediatric uveitis; masquerade syndromes, including inherited retinal degenerations, malignancies, and paraneoplastic syndromes; and much more. Includes the authors' specific thought processes and approach in particularly challenging cases. An excellent resource and study tool for ophthalmology residents and fellows, those studying for oral boards, general ophthalmologists, retina specialists, and more.
The Essentials in Ophthalmology series represents an aged by readership acceptance of the first two series, unique updating publication on the progress in all sub- each of eight volumes. This is a success that was made specialties of ophthalmology. possible predominantly by the numerous opinion-lead- In a quarterly rhythm, eight issues are published cov- ing authors and the outstanding section editors, as well ering clinically relevant achievements in the whole field as with the constructive support of the publisher. There of ophthalmology. This timely transfer of advancements are many good reasons to continue andstill improve the for the best possible care of our eye patients has proven to dissemination of this didactic and clinically relevant be effective. The initial working hypothesis of providing information. new knowledge immediately following publication in the peer-reviewed journal and not waiting for the textbook G. K. Krieglstein appears to be highly workable. R. N. Weinreb We are now entering the third cycle of the Ess- tials in Ophthalmology series, having been encour- Series Editors Preface Our knowledge and understanding of immune-mediated the most recent research material available. The scope of diseases has increased exponentially over the past few the chapters ranges from well-recognized immune dis- years, especially in the areas of immunopathogenesis and ders such as cornea transplantation, uveitis and diabetic immunotherapeutics.
This book discusses the main clinical aspects of common uveitic infectious and non-infectious entities, the diagnostic work-up, and the treatment/management options based on the literature, where available, and clinical experience. Providing a quick reference guide to uveitis and retina fellows as well as general ophthalmologists, this comprehensive book includes chapters on diagnostic biopsy and pediatric uveitis, as well as reference tables and figures. As part of the series "Current Practices in Ophthalmology" this book is intended for residents, fellows-in-training, generalist ophthalmologists and specialists alike.
As a garden is to a gardener, so a book is to its author. Nurtured out of love, both are a source of pride and hope. Microbiology, immunol ogy, infectious diseases, rheumatology, and ophthalmology are the seeds of this textbook on uveitis. Over the years, these branches of medicine have been cultivated and garnered to care for patients with inflammatory diseases of the eye, a most hardy species in the family of ocular maladies. The aim of this clinical manual is to give both a serviceable frame work and practical information on ocular inflammatory disease. The first section is devoted to general principles and commonly held sup positions in the field of uveitis. A system of diagnosis, based on the differential, is also offered. Traumatic uveitis is addressed in the sec ond section. The third part examines infectious diseases that have been identified with uveitis. These are frequently curable forms of ocular inflammation caused by replicating foreign antigens. The fourth section of this textbook considers inflammatory diseases of the eye with a presumed autoimmune mechanism. A disobedient, autoreactive immune response is postulated to playa role in these forms of uveitis. Masquerade and idiopathic conditions are dis cussed in the final chapters. Etiology, epidemiology, pathogenesis, clinical presentation, diagnosis, differential diagnosis, treatment, and prognosis are provided for each disease syndrome. As with most gardens, there are many styles and delightful entrances to the field of uveitis.
The Ocular Inflammatory Disease and Uveitis Manual is a practical, concise clinical reference for resident and practicing ophthalmologists and optometrists treating uveitis patients and an excellent review for the OKAP exam and ophthalmology and optometry boards. Designed for quick point-of-care reference, the book features numerous full-color photographs and bulleted how-to instructions for workup and treatment of each disorder. The state-of-the-art coverage of medical and surgical treatment includes drugs expected to be approved in 2010. The manual is organized into anterior, intermediate, and posterior disease, plus separate sections for corneal and sclera inflammation and infection masquerading syndromes. All topics are further divided into autoimmune and infectious sections, for quick lookup of a disorder.
In this publication, worldwide renowned experts elucidate the ocular phenomenon of uveitis (intraocular inflammation) from different points of view. Summaries of the present knowledge along with detailed outlooks regarding the possibilities of future developments in clinical and basic sciences make 'Uveitis Update' an outstanding compendium of the state of the art in uveitis. The practicing ophthalmologist as well as the internist will find this book a practical guide on the latest treatment methods for uveitis together with a realistic look at future avenues. For the ophthalmic scientist and the ophthalmologist specialized in ocular immunology and inflammation, chapters like 'Newer Methodologies in Immunohistochemistry and Diagnosis', 'Ultrasound as a Diagnostic Tool in Uveitis: UBM and B-Scan', `The Role of Cytokines in Uveitis' or `Management of Ocular Manifestations in AIDS patients' will be of utmost importance.
Uveitis is the comprehensive reference you need for a balanced approach to basic science and clinical application. Robert B. Nussenblatt and Scott M. Whitcup provide a cohesive and integrated discussion of the topic, covering everything from the role of surgery to AIDS to anterior uveitis and more. This new edition even includes full color throughout with 400 photographs and illustrations. Comprehensive yet readable, this resource packs everything you need in patient evaluation and management to achieve optimal results. Covers the medical, pharmacological, and surgical treatment of uveitis to serve as a complete overview of all uveitis related information. Features multiple chapters on diagnostic approach to help you overcome challenges in making accurate diagnoses. Provides additional information on inflammatory eye diseases in chapters on scleritis, masquerade syndromes, and the role of inflammation in other ocular diseases for more comprehensive coverage. Includes illustrated case studies to supplement major clinical points and provide insight into real situations that you can apply in practice. Highlights important information in key points boxes that make it easy to locate crucial points on each topic. Features significant updates to the chapters on the role of surgery in the patient with uveitis, acquired immune deficiency syndrome, anterior uveitis, white dot syndromes, and masquerade syndromes. Covers advancements and new developments on all aspects of uveitis including new medical and surgical treatments. Presents photographs in full color to better prepare you for actual clinical diagnosis.
Based on feedback, the authors have streamlined their bestselling reference to zero in on just the clinical answers ophthalmologists need in day-to-day practice. This new edition presents unparalleled guidance on nearly every ophthalmic condition and procedure.