translational biotechnology

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Translational Biotechnology
Author : Yasha Hasija
Publisher : Academic Press
Release Date : 2021-01-17
ISBN 10 : 0128219734
Pages : 452 pages
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Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Animal Biotechnology
Author : Ashish S. Verma,Anchal Singh
Publisher : Academic Press
Release Date : 2020-07-03
ISBN 10 : 0128117109
Pages : 798 pages
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Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Pharmaceutical Biotechnology
Author : Carlos A. Guzmán,Giora Z. Feuerstein
Publisher : Springer Science & Business Media
Release Date : 2010-01-01
ISBN 10 : 9781441911322
Pages : 276 pages
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Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.

Biotechnology, Gene Gun/biolistic Technology
Author : N.A
Publisher : N.A
Release Date : 1996
ISBN 10 :
Pages : 58 pages
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Basic Biotechnology
Author : Colin Ratledge,Bjorn Kristiansen
Publisher : Cambridge University Press
Release Date : 2006-05-25
ISBN 10 : 0521840317
Pages : 666 pages
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Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are applied; from starting substrate to final product. A distinctive feature of this text are the discussions of the public perception of biotechnology and the business of biotechnology, which set the science in a broader context. This comprehensive textbook is essential reading for all students of biotechnology and applied microbiology, and for researchers in biotechnology industries.

Molecular Biology and Biotechnology
Author : C. A. Smith,E. J. Wood
Publisher : Springer
Release Date : 1991-12-15
ISBN 10 :
Pages : 247 pages
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This series is designed for junior undergraduates and diploma students in all biological sciences, covering the field of modern biochemistry and integrating animal, plant and microbial topics. This volume focuses on the nature and behaviour of genetic material.

Journal of Biotechnology
Author : N.A
Publisher : N.A
Release Date : 1995
ISBN 10 :
Pages : 329 pages
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Genetic Engineering & Biotechnology News
Author : N.A
Publisher : N.A
Release Date : 2009
ISBN 10 :
Pages : 329 pages
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Biotechnology
Author : Pamela Peters
Publisher : McGraw-Hill Science, Engineering & Mathematics
Release Date : 1993
ISBN 10 :
Pages : 253 pages
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Intro. to makeup of DNA & what it does DNA isolation gene cloning factors that govern gene expression.

Genetics and Biotechnology of Bacilli, Volume 2
Author : A. T. Ganesan,James A. Hoch
Publisher : N.A
Release Date : 1988
ISBN 10 : 9780122741616
Pages : 429 pages
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GENETICS & BIOTECHNOLOGY OF BACILLI V2 Z ...

Biotechnology
Author : Hans-Jürgen Rehm,Gerald Reed
Publisher : Weinheim [Germany] ; Toronto : VCH
Release Date : 1995
ISBN 10 : 9783527283224
Pages : 708 pages
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A unique and up-to-date compilation of all important topics in biotechnology. Recent developments such as molecular modelling, transgenic plans and animals, and therapeutic monoclonal antibodies are thoroughly examined, as are DNA probes for diagnostic us

New and Future Developments in Microbial Biotechnology and Bioengineering
Author : Alexandre Gomes Rodrigues
Publisher : Elsevier
Release Date : 2020-06-10
ISBN 10 : 0444643028
Pages : 374 pages
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New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biomolecules: Properties, Relevance and Their Translational Applications presents a concise review on microbial biotechnology, along with impacts and recent results from research centers, small companies and large enterprises. The book brings the most relevant information on how we can use resources—in this case from microorganisms—and technology to develop solutions in fields like biofuels, food, cosmetics and medicine. It covers case studies of start-ups in the field and explains how scientists have moved their ideas into profitable bio-based products that are necessary for our current living standards. In addition, the book describes strategic governmental programs designed to exploit biomass in a sustainable way, along with detailed information on research in several high-impact, worldwide laboratories. It gives concrete examples of ongoing research from molecules to methods, such as L-asparaginase, extremophiles, new diagnostics tools and the analytical methods that have raised the quality of the data obtained, thereby boosting the so-called bioeconomy. Comprises a unique source of information on the various applications of microbial biomolecules Provides resourceful material for new ideas and strong rational/application-oriented stories Discusses biotech companies in various areas (biofuel, food, medicine, etc.) who are actively using microbial biomolecules Outlines scientific discoveries and their translation into profitable products Gives an insight perspective of institutional and governmental strategic research programs aiming to preserve, explore and generate benefits from microbial biomolecules