toxicology cases for the clinical and forensic laboratory

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Toxicology Cases for the Clinical and Forensic Laboratory
Author : Hema Ketha,Uttam Garg
Publisher : Academic Press
Release Date : 2020-06-20
ISBN 10 : 0128163739
Pages : 540 pages
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Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format Presents unique and challenging cases in clinical laboratories contributed by experts in the field Consolidated format that make concepts in toxicology easy to learn and teach Key learning points highlighted with multiple choice questions

Forensic Toxicology
Author : Kalipatnapu N. Rao
Publisher : CRC Press
Release Date : 2012-02-23
ISBN 10 : 1439866821
Pages : 289 pages
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Modern technology using state-of-the-art equipment can now identify almost any toxin relevant to a legal issue. Techniques include gas chromatography, mass spectrometry, high-pressure liquid chromatography, and the combination of these methods. Forensic Toxicology: Medico-legal Case Studies demonstrates how the science of forensic toxicology acts a

Hair Analysis in Clinical and Forensic Toxicology
Author : Pascal Kintz,Alberto Salomone,Marco Vincenti
Publisher : Academic Press
Release Date : 2015-06-25
ISBN 10 : 0128017104
Pages : 392 pages
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Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair Demonstrates toxicological techniques relating to a variety of scenarios and exposure types Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Toxicology
Author : John Joseph Fenton
Publisher : CRC Press
Release Date : 2001-10-10
ISBN 10 : 1420042068
Pages : 600 pages
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REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORY Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduate combined toxicology course at West Chester University, this innovative text captures readers' interest by combining modern case studies, historical cases, and hundreds of illustrations and tables. Each chapter presents several case scenarios that involve the reader with questions about diagnosis, testing methods, treatment, and other pertinent information. TOXICOLOGY FOR THE LABORATORY AND THE EMERGENCY ROOM In an easy-to-read style, this book covers the major organ systems and reviews the effects of toxins in each system. Most contemporary books are almost entirely clinical or entirely analytical. Toxicology: A Case-Oriented Approach treats each area extensively to benefit students and professionals who need to know aspects of both. It describes diagnosis and treatment of each specific poisonous exposure and discusses chemical basis and the laboratory testing of toxins. This dual perspective, coupled with the book's interesting narrative approach, lets readers quickly absorb the information they need to understand toxicology in the laboratory and in the Emergency Department.

Forensic Toxicology
Author : Robert H. Powers,Dorothy E. Dean
Publisher : CRC Press
Release Date : 2015-12-01
ISBN 10 : 1466581956
Pages : 273 pages
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Designed for upper-level undergraduate and graduate-level courses, Forensic Toxicology: Mechanisms and Pathology introduces toxicology concepts from a forensic perspective. The book provides an understanding of the mechanistic basis of the action of drugs and toxins, addressing their physiologic and pathologic consequences on the affected organ sys

Forensic Toxicology
Author : Nicholas T Lappas,Courtney M Lappas
Publisher : Academic Press
Release Date : 2015-11-14
ISBN 10 : 0128004649
Pages : 376 pages
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Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Forensic Toxicology also contains appendices covering the principles of pharmacokinetics and pharmacodynamics, immunology and immunological assays, toxicogenomics, and case studies. Significant emphasis on the fundamental principles and concepts of forensic toxicology Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases The book's companion website, http://textbooks.elsevier.com/web/Manuals.aspx?isbn=9780127999678 features exclusive web-based content

Poisoning
Author : Ntambwe Malangu
Publisher : BoD – Books on Demand
Release Date : 2017-12-20
ISBN 10 : 953513681X
Pages : 218 pages
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This book, which is the result of contributions from a team of international authors, presents a collection of materials that can be categorized into two groups. The first group of papers deals with clinical toxicology topics including poisoning by anticoagulant rodenticides, food toxins, carbon monoxide, the toxicity of beta-lactam antibiotics, acute neonicotinoid poisoning, occupational risk factors for acute pesticide poisoning, activating carbon fibers, and date pits for use in liver toxin adsorption. The second group of papers deals with forensic or analytical toxicology topics such as simplified methods for the analysis of gaseous toxic agents, rapid methods for the analysis and monitoring of pathogens in drinking water and water-based solutions, as well as the linkages between clinical and forensic toxicology. Each chapter presents new information on the topic discussed based on authors' experience while summarizing existing knowledge. As such, this book will be a good teaching aid and can be a prescribed or recommended reading for postgraduate students and professionals in the fields of public health, medicine, pharmacy, nursing, biology, toxicology, and forensic sciences.

Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists
Author : Hans Brandenberger,Robert A. A. Maes
Publisher : Walter de Gruyter
Release Date : 1997-01-01
ISBN 10 : 3110881616
Pages : 762 pages
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Fundamentals of Analytical Toxicology
Author : Robert J. Flanagan
Publisher : John Wiley & Sons
Release Date : 2007
ISBN 10 : 0470319348
Pages : 505 pages
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The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay ? are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: ?This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.? Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists ?Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background ?Boxes?. The many and up to date literature references in each chapter demonstrate the authors? thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.? GTFCh Bulletin ?Toxichem + Krimtech?, May 2008 (translated, original review in German) ?Many toxicologists will add this important reference to their libraries because it competently fills a need ...? International Journal of Toxicology ?The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.? International Journal of Environmental Analytical Chemistry

Principles of Forensic Toxicology
Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
Release Date : 2003
ISBN 10 : 9781890883874
Pages : 385 pages
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Hair Analysis in Clinical and Forensic Toxicology
Author : Pascal Kintz,Alberto Salomone,Marco Vincenti
Publisher : Academic Press
Release Date : 2015-06-25
ISBN 10 : 0128017104
Pages : 392 pages
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Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair Demonstrates toxicological techniques relating to a variety of scenarios and exposure types Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Forensic Science
Author : N.A
Publisher : Elsevier
Release Date : 2000-11-17
ISBN 10 : 9780080531854
Pages : 776 pages
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Forensic Science

First International Symposium On Current Issues of Drug Abuse Testing
Author : Jordi Segura,Rafael de la Torre
Publisher : CRC Press
Release Date : 1991-10-29
ISBN 10 : 9780849342837
Pages : 294 pages
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This book elaborates on the topics covered by top experts in the field of drug testing at an international symposium held in March, 1990. The book is an excellent reference for all professionals involved in the set up, performance and interpretation of results for drug testing programs using biological fluids (especially urine). U.S. and European perspectives are presented in relation to workplace testing. Organizational aspects for reliability of drug testing include topics ranging from sample collection, chain of custody, and laboratory strategies to legal and regulatory aspects. Critical reviews of analytical methodology involve descriptions and critical issues for the major presumptive and confirmatory techniques, including immunological and gas chromatographic-mass spectrometric methodologies. The book's interpretation of results takes into account the metabolic, pharmacokinetic, pharmacodynamic and clinical aspects. The final chapters of the book include topics addressing aspects for potential international harmonization.

Forensic Toxicology
Author : Kalipatnapu N. Rao
Publisher : CRC Press
Release Date : 2012-02-23
ISBN 10 : 1466558962
Pages : 289 pages
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Modern technology using state-of-the-art equipment can now identify almost any toxin relevant to a legal issue. Techniques include gas chromatography, mass spectrometry, high-pressure liquid chromatography, and the combination of these methods. Forensic Toxicology: Medico-legal Case Studies demonstrates how the science of forensic toxicology acts a

Magill's Medical Guide: Paramedics - Zoonoses - Index
Author : Karen E. Kalumuck,Nancy A. Piotrowski,Connie Rizzo,Tracy Irons-Georges
Publisher : N.A
Release Date : 2002
ISBN 10 : 9781587650062
Pages : 2576 pages
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Volume1, A - For. Volume 2 Fra - Par. Volume 3 Par - Z. Index.

Magill's Medical Guide
Author : Nancy A. Piotrowski,Salem Press
Publisher : Salem PressInc
Release Date : 1996
ISBN 10 : 9780893567163
Pages : 948 pages
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Toxicology Testing, An Issue of Clinics in Laboratory Medicine - E-Book
Author : Michael G. Bissell
Publisher : Elsevier Health Sciences
Release Date : 2012-09-24
ISBN 10 : 1455747874
Pages : 240 pages
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This issue of Clinics in Laboratory Medicine, titled Toxicology Testing, includes the following topics; Progress in Clinical Toxicology Testing, The Prescription Drug Abuse Epidemic, Substance Abuse Among Healthcare Professionals, Pain Management Drug Testing, Ethanol Biomarkers, Newly-emerging Drugs of Abuse, Synthetic Cannabinoids, Synthetic Cathenones, Immunoassay Methodology in Drugs-of-abuse Testing, Toxicology Testing in Alternative Specimen Matrices, Principles and Procedures in Postmortem Toxicology, and Pharmacogenetics and the Future of Toxicology Testing. Advances in toxicology testing are paving the way for major improvements in the way scientists evaluate health risks posed by toxic chemicals. Toxicity tests help scientists better understand how the human body carries out normal functions that are key to maintaining health. Therefore, this topic is important to the field of Laboratory Medicine.

Toxicology Studies
Author : Ana Cristina Andreazza,Gustavo Scola
Publisher : BoD – Books on Demand
Release Date : 2015-07-08
ISBN 10 : 9535121405
Pages : 244 pages
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The increased exposure to toxins, toxicants and novel drugs has promoted toxicology to become one of the most important areas of research with emerging innovative toxicity testing protocols, techniques, and regulation being placed. Since the bioactivation of many toxins and toxicants and its consequences on human health are not clearly known, this book offers a quick overview of cellular toxicology through the cell, drug and environmental toxicity. This book does not strive to be comprehensive but instead offers a quick overview of principle aspects of toxins and toxicants in order to familiarize the key principles of toxicology. The book is divided into three main sections,; the first one discusses the role of mitochondrial dysfunction, oxidative stress and mitochondrial drug development. The second and third sections bring light to forensic toxicology and drug poisoning followed by environmental toxicity.

Forensic Nursing Science - E-Book
Author : Virginia A. Lynch,Janet Barber Duval
Publisher : Elsevier Health Sciences
Release Date : 2010-07-23
ISBN 10 : 0323066380
Pages : 704 pages
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Written and edited by the most respected authorities in forensic nursing and forensic sciences, this new edition provides the tools and concepts you need to collect evidence that is admissible in court, determine the significance of that evidence, and provide accurate, reliable testimony while administering high-quality patient care. Now in full color throughout, it remains the most comprehensive, highly illustrated text of its kind. Provides a comprehensive, updated guide to forensic nursing science, paying special attention to the International Association of Forensic Nurses’s (IAFN) goals for forensic nursing. Retains a focus on assessment skills and the collection and preservation of evidence, following the established guidelines of the forensic sciences. Prepares you to provide testimony as a fact witness or a forensic nursing expert. Includes an illustrated case study in almost every chapter, helping you relate the information to clinical practice. Highlights important recommendations for interventions in Best Practice boxes, including the evidence base for each. Summarizes important points in Key Point boxes, so you can quickly review the most important concepts in each chapter. Explores the evolving role of forensic nurses in today’s health care facilities and the community. Edited by Virginia Lynch, founding member and first President of the International Association of Forensic Nurses and Janet Barber Duval, both well-respected pioneers and educators in the field. Contains 300 full-color illustrations integrated throughout the text, so you can view evidence quickly and easily, as it is likely to appear in practice. Presents information on courtroom testimony and depositions in one reorganized, streamlined chapter, giving you a full, organized treatment of this extremely important topic. Includes twelve new chapters: Digital Evidence, Medical Evidence Recovery at the Death Scene, Asphyxia, Electrical and Thermal Injury, Intrafamilial Homicide and Unexplained Childhood Death, Human Trafficking, Credential Development for Forensic Nurses, Gangs and Hate Crimes, Ethics Issues in Forensic Nursing, Forensic Physics and Fracture Analysis, Sexual Deviant Behaviors and Crime and Forensic Epidemiology. Contains heavily revised information on Prehospital Evidence, Forensic Investigation in the Hospital, and Human Abuse and Deaths in Custody. Features critical thinking questions with every case study, so you can thoroughly consider the implications of each clinical scenario. Evolve site will include appendices and additional documentation materials.

Food Toxicology and Forensics
Author : Charis M. Galanakis
Publisher : Academic Press
Release Date : 2020-11-27
ISBN 10 : 0128223618
Pages : 494 pages
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Food Toxicology and Forensics presents an overview on these subjects, along with the analytical tools necessary to handle the complexity of the issues at play between them. The book discusses the presence of foreign substances in food despite forensic analysis and supports the scientific community, laboratories and regulatory bodies in their aim to identify food fraud. Topics include the forensic attribution profiling of food by liquid chromatography (LC), contemporary mass spectrometry (MS), tandem mass spectrometry (MS/MS) and liquid chromatography coupled to mass spectrometry (LC-MS), the application of ambient ionization mass spectrometry (AIMS) techniques for the analysis of food samples, and more. Includes toxicology and analytical methods for the determination of certain toxicants in foods Discusses legal, economic and biological issues of food adulteration and food fraud Presents the latest allergen measurement techniques and post reviews of allergen non-compliance cases Provides methods of validation of DNA biochip for species identification in food forensic science