torsades de pointes

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Acquired Long QT Syndrome
Author : A. John Camm,Marek Malik,Yee Guan Yap
Publisher : John Wiley & Sons
Release Date : 2008-04-15
ISBN 10 : 1405146168
Pages : 208 pages

In recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in mediating cardiac repolarisation. Unfortunately, it is increasingly recognised that a number of drugs, both those associated with altering repolarisation, and others for non-cardiac conditions can increase the propensity for polymorphic ventricular tachycardia, syncope and even ventricular fibrillation and sudden death. In this volume, arrhythmia specialists from St. George’s Hospital Medical School, London discuss the mechanisms behind QT prolongation and torsades de pointes. They focus particularly on the risk of individual cardiac and non-cardiac drugs in provoking long QT syndrome, providing a comprehensive review which will be useful for all electrophysiologists treating polymorphic ventricular tachycardias, and will expose important regulatory issues for pharmaceutical authorities and for the wider medical community.

Chou's Electrocardiography in Clinical Practice E-Book
Author : Borys Surawicz,Timothy Knilans
Publisher : Elsevier Health Sciences
Release Date : 2008-04-22
ISBN 10 : 1437711022
Pages : 752 pages

Widely considered the optimal electrocardiography reference for practicing physicians, and consistently rated as the best choice on the subject for board preparation, this is an ideal source for mastering the fundamental principles and clinical applications of ECG. The 6th edition captures all of the latest knowledge in the field, including expanded and updated discussions of pediatric rhythm problems, pacemakers, stress testing, implantable cardiodefibrillator devices, and much more. It's the perfect book to turn to for clear and clinically relevant guidance on all of today’s ECG applications. Comprehensively and expertly describes how to capture and interpret all normal and abnormal ECG findings in adults and children. Features the expertise of internationally recognized authorities on electrocardiography, for advanced assistance in mastering the subtle but critical nuances of this complex diagnostic modality. Features new chapters on pediatric electrocardiography that explore rhythm problems associated with pediatric obesity, heart failure, and athletic activity. Presents a new chapter on recording and interpreting heart rhythms in patients with pacemakers. Includes new material on interpreting ECG findings associated with implantable cardioverter-defibrillators. Provides fully updated coverage on the increased importance of ECGs in stress testing.

Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond
Author : Esther Pueyo,Blanca Rodriguez
Publisher : Frontiers Media SA
Release Date : 2018-08-16
ISBN 10 : 2889455394
Pages : 329 pages

Current regulatory guidelines for cardiac safety utilize hERG block and QT interval prolongation as risk markers. This strategy has been successful at preventing harmful drugs from being marketed, but criticized for leading to early withdrawal of potentially safe drugs. Here we collected a series of articles presenting new technological and conceptual advances, including refinement of ex vivo and in vitro assays, screens and models, and in silico approaches reflecting the increasing effort that has been put forward by regulatory agencies, industry, and academia to try and address the need of a more accurate, mechanistically-based paradigm of proarrhythmic potential of drugs. This Research Topic is dedicated to the memory of Dr. J. Jeremy Rice, our wonderful friend and colleague.

Critical Decisions in Emergency and Acute Care Electrocardiography
Author : William J. Brady,Jonathon D. Truwit
Publisher : John Wiley & Sons
Release Date : 2011-08-24
ISBN 10 : 1444356194
Pages : 488 pages

This scenario-based text provides answers to urgent and emergent questions in acute, emergency, and critical care situations focusing on the electrocardiogram in patient care management. The text is arranged in traditional topics areas such as ACS, dysrhythmia, etc yet each chapter is essentially a question with several cases illustrating the clinical dilemma – the chapter itself is a specific answer to the question. This is a unique format among textbooks with an ECG focus. The clinical scenarios cover the issues involved in detecting and managing major cardiovascular conditions. Focused, structured discussion then solves these problems in a clinically relevant, rapid, and easy to read fashion. This novel approach to ECG instruction is ideal for practicing critical care and emergency physicians, specialist nurses, cardiologists, as well as students and trainees with a special interest in the ECG.

Drug-induced Diseases
Author : James E. Tisdale,Douglas A. Miller
Publisher : ASHP
Release Date : 2010
ISBN 10 : 1585282057
Pages : 1110 pages

According to the authors, a drug-induced disease as an unintended effect of a drug, which results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical attention and/or require hospitalization. Since the first edition of this book was published in 2005, numerous drugs have been withdrawn from the market in the United States as a result of morbidity and/or mortality associated with drug-induced diseases. Despite best efforts to assure that all drugs are safe and effective, millions of patients each year develop drug-induced diseases. Every time a patient presents with a new disease or an exacerbation of an existing condition, someone needs to ask, "Could this be drug-related? Now in its second edition, this popular and essential comprehensive resource provides a detailed analysis of how to identify, prevent, and manage drug-induced diseases. Edited by James E. Tisdale and Douglas A. Miller, with contributions from experts distinguished in their respective specialties, Drug-Induced Diseases is organized logically and is easy to use for pharmacists, physicians, nurses, and pharmacy students alike. Inside you'll find: Chapters dedicated to each disease state. In-depth tables throughout each chapter. A new section on Drug-Induced dermatologic diseases. New drugs implicated as the cause of specific disease(s). The inclusion of the Levels of Evidence classification scheme for identifying drug-induced diseases. And much more.

Clinical Arrhythmology and Electrophysiology E-Book
Author : Ziad Issa,John M. Miller,Douglas P. Zipes
Publisher : Elsevier Health Sciences
Release Date : 2018-08-07
ISBN 10 : 0323568823
Pages : 752 pages

Part of the highly regarded Braunwald’s family of cardiology references, Clinical Arrhythmology and Electrophysiology, 3rd Edition, offers complete coverage of the latest diagnosis and management options for patients with arrhythmias. Expanded clinical content and clear illustrations keep you fully abreast of current technologies, new syndromes and diagnostic procedures, new information on molecular genetics, advances in ablation, and much more.

Cardiac Repolarization
Author : Nabil El-Sherif
Publisher : Springer Nature
Release Date : 2019-10-24
ISBN 10 : 3030226727
Pages : 354 pages

This book provides a comprehensive, up-to-date overview of clinical and research aspects of cardiac repolarization geared toward practicing cardiologists and physicians. It analyzes elements of pathophysiology and molecular biology as they relate to the clinical aspects of cardiac repolarization, long QT syndromes, early repolarization syndromes, and special cardiac repolarization syndromes. Each chapter examines different aspects of the field with basic and clinical overviews and highlights the impact on medical management. The book covers a variety of repolarization topics including the influence of the autonomic system, racial and gender differences in patients, the future role of stem cells, inflammation and autoimmunity, and cardiovascular risk. Cardiac Repolarization: Basic Science and Clinical Management is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, clinical cardiac electrophysiology, internal medicine, and cardiovascular biology.

Small Animal Critical Care Medicine - E-Book
Author : Deborah Silverstein,Kate Hopper
Publisher : Elsevier Health Sciences
Release Date : 2008-02-13
ISBN 10 : 1416069267
Pages : 1000 pages

Small Animal Critical Care Medicine is a comprehensive, concise guide to critical care, encompassing not only triage and stabilization, but also the entire course of care during the acute medical crisis and high-risk period. This clinically oriented manual assists practitioners in providing the highest standard of care for ICU patients. More than 150 recognized experts offer in-depth, authoritative guidance on clinical situations from a variety of perspectives. Consistent, user-friendly format ensures immediate access to essential information. Organ-system, problem-based approach incorporates only clinically relevant details. Features state-of-the-art invasive and non-invasive diagnostic and monitoring procedures, as well as an extensive section on pharmacology. Appendices provide conversion tables, continuous rate infusion determinations, reference ranges, and more.

Challenging Cases and Complication Management in Pain Medicine
Author : Magdalena Anitescu,Honorio T. Benzon,Mark S. Wallace
Publisher : Springer
Release Date : 2017-11-17
ISBN 10 : 3319600729
Pages : 346 pages

This comprehensive book provides reviews of pain management complications that arise in clinical practice. Organized into sections focused on types of pain therapy and procedures, each chapter is based on actual complications; starting with a case description that delineates the context with a short past medical and surgical history, pain management technique and outcome it is followed by a comprehensive review of the topic described in the first section. Authors emphasize the elements of differential diagnosis that pointed towards establishing of the complication and describe the best way to treat the identified complication. Physicians treating pain patients will be presented the necessary tools in identifying and treating unanticipated complications following pain interventions, thus providing safer care for their patients.

Electrocardiography (ECG)
Author : Jean-Jacques Goy,Jean-Christophe Stauffer,Jürg Schlaepfer,Pierre Christeler
Publisher : Bentham Science Publishers
Release Date : 2013-06-27
ISBN 10 : 1608054799
Pages : 159 pages

This e-book starts with a comprehensive overview of the basic principles in Electrocardiography (ECG) with just enough depth to lift the reader above the crowd when it comes to understanding the physics behind ECG. Subsequent chapters provide an approach to the analysis of the ECG, followed by sections with insight into conduction abnormalities, arrhythmia, and myocardial ischemia. The e-book has a straightforward layout, a very clear format, and abundant ECG tracings for interested readers. The diagnostic algorithms provided in the volume prove to be very useful in daily medical practice. Overall, the e-book will help novice physicians, students and fellows to improve their knowledge in ECG interpretation. Electrocardiography (ECG) is, therefore, a very attractive book for all levels of physicians and health-care professionals interested in ECG and it is a welcome addition to the medical literature.

The Esc Textbook of Cardiovascular Medicine
Author : A. John Camm,Professor of Clinical Cardiology A John Camm,Director of Research Education & Development and Consultant of Cardiology Thomas F Luscher,Thomas F. Luscher,Gerald Maurer,Professor of Cardiology Patrick W Serruys, MD, PhD
Publisher : European Society of Cardiology
Release Date : 2018-11-25
ISBN 10 : 9780198784906
Pages : 2384 pages

This new third edition of The ESC Textbook of Cardiovascular Medicine is a ground breaking initiative from the European Society of Cardiology that is transforming reference publishing in cardiovascular medicine in order to better serve the changing needs of the global cardiology community. Providing the evidence-base behind clinical practice guidelines, with in-depth peer-reviewed articles and broad coverage of this fast-moving field, both the print and digital publication are invaluable resources for cardiologists across the world. Overseen by Professors A. John Camm, Thomas F. Lüscher, Patrick W. Serruys, and Gerald Maurer, supported by an editorial board of subject experts, and more than 900 of the world's leading specialists from research and the clinic contributing, this dynamic encyclopaedic resource covers more than 63 disciplines within cardiology. Split into six key parts; Introduction to the cardiovascular system; Investigations; Heart diseases; Vascular disease; Special populations, and Other aspects of cardiology, providing readers with a trustworthy insight into all aspects of cardiovascular medicine. To respond nimbly to the rapid evolution of the field the digital publication, ESC CardioMed, is continuously updated by the author teams. With expert editors and authors, and stringent peer-review, the publication combines the discoverability of digital with the highest standards of academic publishing. Highly illustrated with embedded multi-media features, along with cross-referenced links to ESC Clinical Practice Guidelines, related content and primary research data in European Heart Journal, as well as all other major journals in the field, ESC CardioMed provides users with the most dynamic and forward thinking digital resource at the heart of cardiology. As a consistently evolving knowledge base, the ESC Textbook of Cardiovascular Medicine 3e together with the online counterpart ESC CardioMed, equips all those, from trainees and consultants, to device specialists and allied healthcare professionals with a powerful, multifaceted resource covering all aspects of cardiovascular medicine.

Consults in Obstetric Anesthesiology
Author : Suzanne K. W. Mankowitz
Publisher : Springer
Release Date : 2018-11-15
ISBN 10 : 3319596802
Pages : 699 pages

This text addresses the need for a book specifically aimed at obstetric anesthesia and covers topics such as pulmonary, cardiac renal, hepatic, hematologic, neurologic, endocrine and other diseases. The real anesthetic challenge arises when patients present to Labor and Delivery with unusual or complicated medical problems and, in recent years, a few of the larger institutions have developed an Obstetric Anesthesiology Consultation Service to prepare for the management of these patients. While most pregnant women who present to Labor and Delivery require anesthetic intervention, they typically meet the anesthesiologist for the first time in labor. Since the majority of laboring women are healthy without significant comorbidities, this does not present much of a challenge to the anesthesiologist and the anesthetic management tends to be straight-forward with favorable outcomes. However, using this new model, the anesthesiologist has the opportunity to discuss the various treatment modalities and potentially suggest diagnostic testing to be performed prior to delivery, similar to the pre-operative testing that is done in other surgical environments.

Field Guide to the Arrhythmias
Author : Ellis Lader
Publisher : John Wiley & Sons
Release Date : 2013-02-26
ISBN 10 : 1118386132
Pages : 176 pages

...The cardiac unit is a jungle, inhabited by fierce nurses, killer intensivists, marauding attendings, various flesh-eating specialists, sick patients, and lots of arrhythmias. –from the Preface Can you recognize the call of the normal sinus rhythm? Name the natural habitat of Multifocal Atrial Tachycardia or Ventricular Fibrillation? Are you well-versed in the proper care and feeding of Asystole and Atrial Flutter? If you answered “no” to any of these questions, then you need this trusty guide to help you identify and respond to arrhythmias in the veritable wilderness of the busy hospital ward. Created by a seasoned physician educator at a major urban medical center and inspired by the “field guides” used by birders, botanists and the like to identify flora or fauna in the wild, this new book offers a unique – and uniquely humorous -- approach to mastering the ever-vexing challenge of arrhythmia identification. Each arrhythmia is covered beginning with a sample ECG strip, followed by brief text describing its significant characteristics; where and when it is likely to be encountered (its “Habitat”); comments, questions and queries likely to be heard from physicians and other colleagues on the ward (the “Call”); and finally what steps the reader needs to take upon identifying the arrhythmia in a patient (“Care and Feeding”). Dr. Lader’s approach brings the sights and sounds of a modern hospital to life, enabling you to understand arrhythmia diagnosis and clinical response in context, and his offbeat, sometimes irreverent humor makes each detail memorable. Fifty self-assessment questions are included to help you master arrhythmia essentials and test your knowledge.

Electrocardiography in Clinical Practice
Author : Te-Chuan Chou
Publisher : Saunders
Release Date : 1986
ISBN 10 :
Pages : 679 pages

Cardiac Arrhythmias
Author : Wilbert S. Aronow
Publisher : BoD – Books on Demand
Release Date : 2014-02-12
ISBN 10 : 953511221X
Pages : 162 pages

This book is useful for physicians taking care of patients with cardiac arrhythmias and includes six chapters written by experts in their field. Chapter 1 discusses basic mechanisms of cardiac arrhythmias. Chapter 2 discusses the chronobiological aspects of the impact of apnoic episodes on ventricular arrhythmias. Chapter 3 discusses navigation, detection, and tracking during cardiac ablation interventions. Chapter 4 discusses epidemiology and pathophysiology of ventricular arrhythmias in several noncardiac diseases, methods used to assess arrhythmia risk, and their association with long-term outcomes. Chapter 5 discusses the treatment of ventricular arrhythmias including indications for implantation of an AICD for primary and for secondary prevention in patients with and without congestive heart failure. Chapter 6 discusses surgical management of atrial fibrillation.

Author : Marc Gertsch
Publisher : Springer Science & Business Media
Release Date : 2004
ISBN 10 : 9783540008699
Pages : 615 pages

Professor Gertsch covers both clinically relevant ECGs and very interesting rarer cases of the normal and the exercise ECG, making this work extremely comprehensive - it represents the culmination of a lifetime of involvement with invasive and non-invasive cardiology by one of Switzerland's leading cardiologists. Numerous ECGs and two-color drawings illustrate the text, which is also brought closer to the reader by means of over fifty case reports. Ease of reference is facilitated by the division of the text into separate sections: "At a Glance" for readers who want quick information, and "The Full Picture" for readers wishing to go into exhaustive detail. Foreword by Christopher Cannon.

Clinical Cardiology: Current Practice Guidelines
Author : Demosthenes G. Katritsis,Bernard J. Gersh,A. John Camm
Publisher : Oxford University Press
Release Date : 2016-07-21
ISBN 10 : 0191081582
Pages : 880 pages

Clinical Cardiology: Current Practice Guidelines Updated Edition is an essential tool for the busy clinician, offering succinct yet detailed access to the most recent trial and guideline data supporting practice and patient management in cardiology. ESC and ACC/AHA guidelines are continually updated and often overlap in their advice, making it difficult for the cardiologist to obtain a clear picture of the right way to diagnose and treat disease according to the latest evidence base. Written by leading authorities in the field, this book, together with its regularly-updated online version, provides a unique solution. The authors have scrutinized all available guidelines and research from both ACC/AHA and ESC on every clinical issue. The result is a rigorous examination of the implications of published guidance, illustrated by more than 600 easy-to-follow tables and 200 full-colour images, which reinforce key points and clarify difficult concepts. 87 comprehensive chapters explore the definition, epidemiology, pathophysiology, diagnosis and management of cardiac disease. Two new chapters examine the univentricular heart and venous thrombembolism. Each chapter encompasses the latest published research, followed by discussions of possible presentations and investigations, offering detailed insights for clinicians into best practice for diagnosis and treatment. Providing at-a-glance access to the best guidance in cardiology, this book offers a diagnosis and management toolkit which no practising cardiologist can afford to be without.

Delmar Nurse's Drug Handbook 2011: Special 20 Year Anniversary
Author : George Spratto,Adrienne Woods
Publisher : Nelson Education
Release Date : 2010-06-16
ISBN 10 : 1133171702
Pages : 2208 pages

For 20 years, the Delmar Nurse’s Drug Handbook continues to be an essential resource for the most important drug information with over 1,000 of the latest and most common FDA-approved drugs, Each entry provides a wealth of facts concerning drug action, dosage, interactions, and contraindications. Clear guidelines are also provided for administration of drugs, communication with clients, and nursing considerations. The Delmar Nurse’s Drug Handbook 2011: Special 20-Year Anniversary Edition highlights prevention of medication errors and clinical accountability like no other drug resource, making it a trusted resource for nursing students, practicing nurses, and other health care professionals. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Cardiac Arrhythmia
Author : Philip J. Podrid,Peter R. Kowey
Publisher : Lippincott Williams & Wilkins
Release Date : 2001
ISBN 10 : 9780781724869
Pages : 973 pages

The Second Edition of this clinically oriented textbook about cardiac arrhythmia management continues to be a must-have volume for practicing cardiologists and internists, who require up-to-date information for the daily management of their patients. The material, prepared by recognized experts in the field, presents an in-depth look at diagnostic and treatment protocols in a readable, well-organized format. Unique chapters regarding pregnancy, athletes, and genetics also are included. A Brandon-Hill recommended title.

Management of Cardiac Arrhythmias
Author : Gan-Xin Yan
Publisher : Springer Nature
Release Date :
ISBN 10 : 3030419673
Pages : 329 pages