The Wolff-Kishner Reduction and Related Reactions: Discovery and Development offers a detailed discussion of this reaction, its discoverers, and its development since its discovery. Derivative name reactions—including the Wharton and Shapiro reactions—are also discussed. The book is illustrated with examples from literature and corresponding references to the primary literature to aid further reading. It provides a comprehensive review of the century of chemistry that allows the reader to follow the development of this important synthetic reaction. In addition, it provides biographical details on the chemists who discovered and developed the reaction, thus adding a human dimension to the discussion. Introduces Wolff and Kishner, the discoverers of the reaction, along with Huang Ming-Long, the developer of an important modification of the reaction Discusses the discovery of the reaction and the way that priority for the discovery was settled between Wolff and Kishner Discusses, in depth, the development and usage of the reaction over the century, from its discovery, to its most recent applications and modifications in synthesis Includes biographical materials on the chemists responsible for major derivative name reactions based on the Wolff-Kishner reduction
This book summarizes 100 essential mechanisms in organic chemistry ranging from classical such as the Reformatsky Reaction from 1887 to recently elucidated mechanism such as the copper(I)-catalyzed alkyne-azide cycloaddition. The reactions are easy to grasp, well-illustrated and underpinned with explanations and additional information.
1. Catalytic hydrogenation and dehydrogenation 1; 2. Metal hydride reductions and related reactions 45; 3. Dissolving metal reductions and related reactions 145; 4. Reductions with hydrazine and its derivatives 228; 5. Oxidations with chromium and manganese compounds 257; 6. Oxidation with peracids and other peroxides 292; 7. Other methods of oxidation 353; 8. Halogenation 422; 9. The alkylation of active methylene compounds 492; 10. The aldol condensation and related reactions 629; 11. Acylation at carbon 734.
|Author||: Laszlo Kurti,Barbara Czako|
|Release Date||: 2005-04-29|
|ISBN 10||: 0080575412|
|Pages||: 864 pages|
Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings
|Author||: Michael Leonard|
|Release Date||: 2013-10|
|ISBN 10||: 1304515893|
|Pages||: 364 pages|
To master Organic Chemistry, it is essential to master mechanism. This book uses a novel approach to help you better understand the mechanisms of 80 common organic reactions. Each one is color coded so that you can clearly see the changes that take place during the reaction. The electrons involved in the mechanism are color coded, as are the arrows originating from those electrons and the bonds or lone pairs formed by them in the intermediates and product. As a result, you can trace specific pairs of electrons through an entire transformation. The description of what each mechanistic arrow means is color coded correspondingly so that it is easy to match up the text with the relevant portion of a reaction diagram.
This Second edition contains consise information on 134 carefully chosen named organic reactions - the standard set of undergraduate and graduate synthetic organic chemistry courses. Each reaction is detailed with clearly drawn mechanisms, references from the primary literature, and well-written accounts covering the mechanical aspects of the reactions, and the details of side reactions and substrate limitations. For the 2nd edition the complete text has been revised and updated, and four new reactions have been added: Baylis-Hillmann Reaction, Sonogashira Reaction, Pummerer Reaction, and the Swern Oxidation und Cyclopropanation. An essential text for students preparing for exams in organic chemistry.
|Author||: Stanley R. Sandler,Wolf Karo|
|Publisher||: Academic Press|
|Release Date||: 2012-12-02|
|ISBN 10||: 0080925537|
|Pages||: 352 pages|
In the case of students, this laboratory preparations manual can be used to find additional experiments to illustrate concepts in synthesis and to augment existing laboratory texts. A name reaction index is also included to direct the reader to the location where specific reactions appear in this manual. The industrial chemist is frequently required to prepare a variety of compounds, and this manual can serve as a convenient guide to choose a synthetic route. Key Features * Offers detailed directions for the synthesis of various functional groups * Includes up-to-date references to the journal literature and patents (foreign and domestic) * Reviews the chemistry for each functional group with suggestions where additional research is needed * Name reactions are indexed along with the preparations cited
|Release Date||: 1982|
|Pages||: 329 pages|
The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively