the neuroscience of pain

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Neuroscience of Pain, Stress, and Emotion
Author : Magne Arve Flaten,Mustafa al'Absi
Publisher : Academic Press
Release Date : 2015-12-28
ISBN 10 : 0128006668
Pages : 312 pages

Neuroscience of Pain, Stress, and Emotion: Psychological and Clinical Implications presents updated research on stress, pain, and emotion, all key research areas within both basic and clinical neuroscience. Improved research understanding of their interaction is ultimately necessary if clinicians and those working in the field of psychosomatic medicine are to alleviate patient suffering. This volume offers broad coverage of that interaction, with chapters written by major researchers in the field. After reviewing the neuroscience of pain and stress, the contents go on to address the interaction between stress and chronic/acute pain, the role of different emotions in pain, neurobiological mechanisms mediating these various interactions, individual differences in both stress and pain, the role of patient expectations during treatment (placebo and nocebo responses), and how those relate to stress modulation. While there are books on the market which discuss pain, stress, and emotion separately, this volume is the first to tackle their nexus, thus appealing to both researchers and clinicians. Represents the only comprehensive reference detailing the link between pain, stress and emotion, covering the neuroscientific underpinnings, related psychological processes, and clinical implications Compiles, in one place, research which promises to improve the methodology of clinical trials and the use of knowledge of pain-stress-emotion effects in order to reduce patients’ suffering Provides comprehensive chapters authored by global leaders in the field, the broadest, most expert coverage available

Why do I hurt? : a patient book about neuroscience of pain: Neuroscience education for patients in pain
Author : Adriaan Louw
Publisher : N.A
Release Date : 2013
ISBN 10 : 9780985718626
Pages : 52 pages

The Oxford Handbook of the Neurobiology of Pain
Author : Professor John N. Wood
Publisher : Oxford University Press
Release Date : 2020-06-17
ISBN 10 : 0190860529
Pages : 512 pages

The Oxford Handbook of the Neurobiology of Pain represents a state of the art overview of the rapidly developing field of pain research. As populations age, the number of people in pain is growing dramatically, with half the population living with pain. The opioid crisis has highlighted this problem. The present volume is thus very timely, providing expert overviews of many complex topics in pain research that are likely to be of interest not just to pain researchers, but also to pain clinicians who are seeking new therapeutic opportunities to develop analgesics. Many of the topics covered are of interest to neuroscientists, as pain is one of the most amenable sensations for mechanistic dissection. The present volume covers all aspects of the topic, from a history of pain through invertebrate model systems to the human genetics of pain and functional imaging. Chapters include the role of ion channels, the opioid system, the immune and sympathetic systems, as well as the mechanisms that transform acute to chronic pain. Migraine and the interplay between sleep and pain are also discussed. New technology in the form of transgenic animals, chemogenetics, optogenetics, and proteomic analyses are providing significant advances in our research and are covered as well. Demystifying pain through an understanding of its fundamental biology, as outlined in this volume, is the most direct route to ameliorating this vast human problem.

An Introduction to Pain and Its Relation to Nervous System Disorders
Author : Anna A. Battaglia
Publisher : John Wiley & Sons
Release Date : 2016-05-02
ISBN 10 : 1118455916
Pages : 440 pages

"Provides an accessible overview of the latest developments in the science underpinning pain research"--

The Story of Pain
Author : Joanna Bourke
Publisher : OUP Oxford
Release Date : 2014-06-26
ISBN 10 : 0191003557
Pages : 336 pages

Everyone knows what is feels like to be in pain. Scraped knees, toothaches, migraines, giving birth, cancer, heart attacks, and heartaches: pain permeates our entire lives. We also witness other people - loved ones - suffering, and we 'feel with' them. It is easy to assume this is the end of the story: 'pain-is-pain-is-pain', and that is all there is to say. But it is not. In fact, the way in which people respond to what they describe as 'painful' has changed considerably over time. In the eighteenth and nineteenth centuries, for example, people believed that pain served a specific (and positive) function - it was a message from God or Nature; it would perfect the spirit. 'Suffer in this life and you wouldn't suffer in the next one'. Submission to pain was required. Nothing could be more removed from twentieth and twenty-first century understandings, where pain is regarded as an unremitting evil to be 'fought'. Focusing on the English-speaking world, this book tells the story of pain since the eighteenth century, addressing fundamental questions about the experience and nature of suffering over the last three centuries. How have those in pain interpreted their suffering - and how have these interpretations changed over time? How have people learnt to conduct themselves when suffering? How do friends and family react? And what about medical professionals: should they immerse themselves in the suffering person or is the best response a kind of professional detachment? As Joanna Bourke shows in this fascinating investigation, people have come up with many different answers to these questions over time. And a history of pain can tell us a great deal about how we might respond to our own suffering in the present - and, just as importantly, to the suffering of those around us.

Relieving Pain in America
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Advancing Pain Research, Care, and Education
Publisher : National Academies Press
Release Date : 2011-10-26
ISBN 10 : 030921484X
Pages : 382 pages

Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Explain Pain
Author : David S Butler,G Lorimer Moseley
Publisher : Noigroup Publications
Release Date : 2013-07
ISBN 10 : 0987342673
Pages : 133 pages

Imagine an orchestra in your brain. It plays all kinds of harmonious melodies, then pain comes along and the different sections of the orchestra are reduced to a few pain tunes. All pain is real. And for many people it is a debilitating part of everyday life. It is now known that understanding more about why things hurt can actually help people to overcome their pain. Recent advances in fields such as neurophysiology, brain imaging, immunology, psychology and cellular biology have provided an explanatory platform from which to explore pain. In everyday language accompanied by quirky illustrations, Explain Pain discusses how pain responses are produced by the brain: how responses to injury from the autonomic motor and immune systems in your body contribute to pain, and why pain can persist after tissues have had plenty of time to heal. Explain Pain aims to give clinicians and people in pain the power to challenge pain and to consider new models for viewing what happens during pain. Once they have learnt about the processes involved they can follow a scientific route to recovery. The Authors: Dr Lorimer Moseley is Professor of Clinical Neurosciences and the Inaugural Chair in Physiotherapy at the University of South Australia, Adelaide, where he leads research groups at Body in Mind as well as with Neuroscience Research Australia in Sydney. Dr David Butler is an international freelance educator, author and director of the Neuro Orthopaedic Institute, based in Adelaide, Australia. Both authors continue to publish and present widely.

Transplantation of Neural Tissue Into the Spinal Cord
Author : Antal Nogradi
Publisher : Springer Science & Business Media
Release Date : 2006
ISBN 10 : 9780387263557
Pages : 150 pages

Transplantation of Neural Tissues into the Spinal Cord presents both recent and early results from various experiments where grafts of neuronal, glial and other tissues, as well as artificial materials, were placed into the spinal cord. This book is evaluates the contribution and effect of these studies to our understanding of basic neurobiological questions. This second edition of the book provides answers to many questions which could not be answered in the first edition, and accordingly all the chapters have been extensively rewritten and edited. The findings summarized in this edition show that grafted tissue can survive and thrive in a host mammal, occasionally replace some lost function and re-establish a semblance of sophisticated and complex circuitries. These new insights are among the most exciting in neurobiology, for they challenge the view that nothing can grow or regenerate in the central nervous system and give new hope that it may be possible to treat some of the incurable diseases of the CNS.

Social Pain
Author : Geoff MacDonald,Lauri A. Jensen-Campbell
Publisher : Amer Psychological Assn
Release Date : 2011
ISBN 10 :
Pages : 258 pages

Social pain is the experience of pain as a result of interpersonal rejection or loss, such as rejection from a social group, bullying, or the loss of a loved one. Research now shows that social pain results from the activation of certain components in physical pain systems. Although social, clinical, health, and developmental psychologists have each explored aspects of social pain, recent work from the neurosciences provides a coherent, unifying framework for integrative research. This edited volume provides the first comprehensive, multidisciplinary exploration of social pain. Part I examines the subject from a neuroscience perspective, outlining the evolutionary basis of social pain and tracing the genetic, neurological, and physiological underpinnings of the phenomenon. Part II explores the implications of social pain for functioning in interpersonal relationships; contributions examine the influence of painkillers on social emotions, the ability to relive past social hurts, and the relation of social pain to experiences of intimacy. Part III examines social pain from a biopsychosocial perspective in its consideration of the health implications of social pain, outlining the role of stress in social pain and the potential long-term health consequences of bullying. The book concludes with an integrative review of these diverse perspectives.

Therapeutic neuroscience education : teaching patients about pain : a guide for clinicians
Author : Adriaan Louw,Emilio Puentedura
Publisher : N.A
Release Date : 2013
ISBN 10 : 9780985718640
Pages : 292 pages

Evidence shows that patients who better understand their pain, and what pain truly is, experience less pain, have less fear, move better, exercise more and can regain hope. In this textbook, physical therapists Adriaan Louw and Emilio Puentedura deliver an evidence-based perspective on how the body and brain collaborate to create pain, teach how to convey this view of pain to patients, and demonstrate how to integrate therapeutic neuroscience education into a practice.--

The Neuroscience of Chronic Pain Relief
Author : Davoud Derogar
Publisher : Independently Published
Release Date : 2019-04-07
ISBN 10 : 9781093154061
Pages : 104 pages

To anyone who has chronic pain. If the pain is robbing you of your quality-of-life. If pain is stopping you from enjoying time with your family and friends. If pain is stopping you from your hobbies and interests. If the pain is stopping you from being active and in control. I hope this book will give you a better understanding of chronic pain so that you can eliminate your pain, reduce or manage your pain better and have a joyful life. Please be open minded. I am sure this book will help you to ease your pain and possibly get rid of pain that is holding you back in life.

Neuropathic Pain
Author : Cory Toth,Dwight E. Moulin
Publisher : Cambridge University Press
Release Date : 2013-11-07
ISBN 10 : 1107470439
Pages : 384 pages

Central or peripheral neuropathic pain can be caused by a wide range of injuries, infections and diseases such as: spinal cord injury, multiple sclerosis, stroke, herpes zoster, diabetes and cancer. Many of these pain syndromes are difficult to treat, representing a challenge for many neurologists not routinely trained in pain management. Written by an international team of experts in the field, Neuropathic Pain: Causes, Management and Understanding gives readers an in-depth understanding of the multitude of conditions causing neuropathic pain. Epidemiology, clinical diagnosis, pathophysiology, outcome measurement and the best evidence-based management of individual and general neuropathic pain conditions are also described in depth. A unique chapter, written from a patient's viewpoint, gives new insight into how chronic neuropathic pain affects the lives of those patients with the condition. This book is essential reading for all pain specialists, neurologists, psychiatrists and anesthesiologists who wish to better understand their patients' neuropathic pain.

The Neurobiology of Pain
Author : Stephen P. Hunt,Martin Koltzenburg
Publisher : Molecular and Cellular Neurobi
Release Date : 2005
ISBN 10 : 9780198515616
Pages : 403 pages

Within the last decade we have seen major new advances in the neurobiology of pain. The topic has emerged as a separate field of study in its own right. This volume presents a state-of-the-art account of the neurobiological basis of pain, by leading scientists in this field.

The Brain's Way of Healing
Author : Norman Doidge
Publisher : Penguin
Release Date : 2015-01-27
ISBN 10 : 0698191439
Pages : 432 pages

NEW YORK TIMES BESTSELLER The New York Times–bestselling author of The Brain That Changes Itself presents astounding advances in the treatment of brain injury and illness. Now in an updated and expanded paperback edition. Winner of the 2015 Gold Nautilus Award in Science & Cosmology In his groundbreaking work The Brain That Changes Itself, Norman Doidge introduced readers to neuroplasticity—the brain’s ability to change its own structure and function in response to activity and mental experience. Now his revolutionary new book shows how the amazing process of neuroplastic healing really works. The Brain’s Way of Healing describes natural, noninvasive avenues into the brain provided by the energy around us—in light, sound, vibration, and movement—that can awaken the brain’s own healing capacities without producing unpleasant side effects. Doidge explores cases where patients alleviated chronic pain; recovered from debilitating strokes, brain injuries, and learning disorders; overcame attention deficit and learning disorders; and found relief from symptoms of autism, multiple sclerosis, Parkinson’s disease, and cerebral palsy. And we learn how to vastly reduce the risk of dementia, with simple approaches anyone can use. For centuries it was believed that the brain’s complexity prevented recovery from damage or disease. The Brain’s Way of Healing shows that this very sophistication is the source of a unique kind of healing. As he did so lucidly in The Brain That Changes Itself, Doidge uses stories to present cutting-edge science with practical real-world applications, and principles that everyone can apply to improve their brain’s performance and health. From the Trade Paperback edition.

The Myth of Pain
Author : Valerie Gray Hardcastle
Publisher : MIT Press
Release Date : 2001
ISBN 10 : 9780262582100
Pages : 298 pages

Valerie Gray Hardcastle argues that both professional and lay definitions of pain are wrongheaded -- with consequences for how pain and pain patients are treated, how psychological disorders are understood, and how clinicians define the mind/body relationship. Pain, although very common, is little understood. Worse still, according to Valerie Gray Hardcastle, both professional and lay definitions of pain are wrongheaded -- with consequences for how pain and pain patients are treated, how psychological disorders are understood, and how clinicians define the mind/body relationship. Hardcastle offers a biologically based complex theory of pain processing, inhibition, and sensation and then uses this theory to make several arguments: (1) psychogenic pains do not exist; (2) a general lack of knowledge about fundamental brain function prevents us from distinguishing between mental and physical causes, although the distinction remains useful; (3) most pain talk should be eliminated from both the folk and academic communities; and (4) such a biological approach is useful generally for explaining disorders in pain processing. She shows how her analysis of pain can serve as a model for the analysis of other psychological disorders and suggests that her project be taken as a model for the philosophical analysis of disorders in psychology, psychiatry, and neuroscience.

The Routledge Handbook of Philosophy of Pain
Author : Jennifer Corns
Publisher : Routledge
Release Date : 2017-07-14
ISBN 10 : 1317585453
Pages : 456 pages

The phenomenon of pain presents problems and puzzles for philosophers who want to understand its nature. Though pain might seem simple, there has been disagreement since Aristotle about whether pain is an emotion, sensation, perception, or disturbed state of the body. Despite advances in psychology, neuroscience, and medicine, pain is still poorly understood and multiple theories of pain abound. The Routledge Handbook of Philosophy of Pain is an outstanding reference source to the key topics, problems, and debates in this exciting and interdisciplinary subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors the Handbook is divided into nine clear parts: Modeling pain in philosophy Modeling pain in neuroscience Modeling pain in psychology Pain in philosophy of mind Pain in epistemology Pain in philosophy of religion Pain in ethics Pain in medicine Pain in law As well as fundamental topics in the philosophy of pain such as the nature, role, and value of pain, many other important topics are covered including the neurological pathways involved in pain processing; biopsychosocial and cognitive-behavioural models of pain; chronic pain; pain and non-human animals; pain and knowledge; controlled substances for pain; pain and placebo effects; and pain and physician-assisted suicide. The Routledge Handbook of Philosophy of Pain is essential reading for students and researchers in philosophy of mind, philosophy of psychology and ethics. It will also be very useful to researchers of pain from any field, especially those in psychology, medicine, and health studies.

The Body in Pain
Author : Elaine Scarry
Publisher : Oxford University Press, USA
Release Date : 1987
ISBN 10 : 9780195049961
Pages : 385 pages

Discusses the inexpressibility of physical pain and analyzes the philosophical and cultural aspects of pain, torture, and war

Pain and Disability
Author : Institute of Medicine,Committee on Pain, Disability, and Chronic Illness Behavior
Publisher : National Academies Press
Release Date : 1987-01-01
ISBN 10 : 0309037379
Pages : 320 pages

Pain--it is the most common complaint presented to physicians. Yet pain is subjective--it cannot be measured directly and is difficult to validate. Evaluating claims based on pain poses major problems for the Social Security Administration (SSA) and other disability insurers. This volume covers the epidemiology and physiology of pain; psychosocial contributions to pain and illness behavior; promising ways of assessing and measuring chronic pain and dysfunction; clinical aspects of prevention, diagnosis, treatment, and rehabilitation; and how the SSA's benefit structure and administrative procedures may affect pain complaints.

Philosophy of Pain
Author : David Bain,Michael Brady,Jennifer Corns
Publisher : Routledge
Release Date : 2018-07-11
ISBN 10 : 1351115847
Pages : 224 pages

Over recent decades, pain has received increasing attention as philosophers, psychologists, and neuroscientists try to answer deep and difficult questions about it. What is pain? What makes pain unpleasant? How is pain related to the emotions? This volume provides a rich and wide-ranging exploration of these questions and important new insights into the philosophy of pain. Divided into three clear sections – pain and motivation, pain and emotion, and deviant pain – the collection covers fundamental topics in the philosophy and psychology of pain. These include pain and sensory affect, the neuroscience of pain, pain and rationality, placebos, and pain and consciousness. Philosophy of Pain: Unpleasantness, Emotion, and Deviance is essential reading for students and researchers in philosophy of mind, philosophy of psychology, cognitive and behavioral psychology, as well as those in health and medicine researching conceptual issues in pain.

Conn's Translational Neuroscience
Author : P. Michael Conn
Publisher : Academic Press
Release Date : 2016-09-28
ISBN 10 : 0128025964
Pages : 776 pages

Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment