the neurobiology of schizophrenia

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The Neurobiology of Schizophrenia
Author : Ted Abel,Thomas Nickl-Jockschat
Publisher : Academic Press
Release Date : 2016-07-08
ISBN 10 : 0128018771
Pages : 468 pages
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The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Integrating the Neurobiology of Schizophrenia
Author : N.A
Publisher : Elsevier
Release Date : 2007-02-27
ISBN 10 : 9780080475080
Pages : 480 pages
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This book examines the role that dopamine plays in schizophrenia, examining its role in not only the symptoms of the disease but also in its treatment. It also reviews all neurotransmitters that have been implicated in schizophrenia, exploring the genetic data, clinical data implicating the transmitter, and the preclinical data exploring how a transmitter may interact with dopamine and contribute to the dopaminergic phenotype observed in the illness. This book will serve as an educational tool for instructors, a guide for clinicians, and be of interest to researchers. It is a good reference for researchers specialized in one particular area and interested in learning about other areas of pathology in schizophrenia and how they may all feed into each other. The book concludes with an overall integrative model assembling as many of these elements as possible.

Neurobiology of Mental Illness
Author : Dennis S. Charney,Eric J. Nestler,Pamela Sklar,Joseph D. Buxbaum
Publisher : Oxford University Press
Release Date : 2013-07-04
ISBN 10 : 0199934959
Pages : 1222 pages
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Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Behavioral Neurobiology of Schizophrenia and Its Treatment
Author : Neal R. Swerdlow
Publisher : Springer Science & Business Media
Release Date : 2010-08-19
ISBN 10 : 9783642137174
Pages : 666 pages
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This book describes the state-of-the-art of treatment of schizophrenia and reflects its development in 22 chapters written by leading authorities in the field

Charney & Nestler's Neurobiology of Mental Illness
Author : Dennis S. Charney,Pamela B. Sklar
Publisher : Oxford University Press
Release Date : 2018-01-12
ISBN 10 : 019068142X
Pages : 1024 pages
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Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.

Schizophrenia and Related Disorders
Author : Michael J. Marcsisin,Jessica M. Gannon
Publisher : Oxford University Press
Release Date : 2016-10-20
ISBN 10 : 0199331502
Pages : 280 pages
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Psychotic disorders are common and important psychiatric conditions, and patients suffering from psychosis can be challenging to assess and manage. In this new monograph, experts in schizophrenia and related psychoses review the current state of science in this area, and provide a practical and readable overview of the how to diagnose and treat individuals presenting with these disorders. This pocket-sized text features call-out boxes, case descriptions, practical tips, and general guidelines that should be ideal for medical students, residents, young mental health professionals, and trainees in other fields. Beginning with a history of psychosis, the authors proceed to explore the phenomenology of symptoms and experiences and how these can be used in clinical assessment. Diagnostic criteria are reviewed, along with common conditions in the differential diagnosis. Subsequent chapters tackle epidemiology, course and prognosis, and the neurobiology of psychotic disorders. The book concludes with chapters on treatment, both somatic and psychosocial, including discussion of novel interventional approaches and service delivery. The authors of this text are a mix of clinician-educators and scientific investigators, all with experience teaching trainees; this pocket-sized book has been developed to help young professionals easily gain a basic understanding of the complexities and challenges of psychotic disorders. Self-assessment questions, resources, and references will assist, but what really sets this book apart is the accessibility and concision of the text, ideal for individuals learning about or reviewing psychosis.

Neurobiology of Brain Disorders
Author : Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publisher : Elsevier
Release Date : 2014-12-03
ISBN 10 : 0123982804
Pages : 824 pages
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Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Advances in the Neurobiology of Schizophrenia
Author : Johan A. den Boer,H. G. M. Westenberg,Herman M. Van Praag
Publisher : John Wiley & Son Limited
Release Date : 1995-07-11
ISBN 10 :
Pages : 469 pages
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Recent years have witnessed major advances in the study of neuroscience which have increased our understanding of the relationship between cerebral processes and behavioural, cognitive and emotional disorders. This series aims to monitor important research developments in the field of biological psychiatry and their relevance to clinical practice. Since the 1950s there has been significant progress in our understanding of the neurobiology of schizophrenia. This important volume illustrates these new developments, particularly in terms of pharmacotherapeutics, pathogenesis and research methodology. Eminent scientists from around the world discuss conceptual issues, epidemiology, genetic analysis of psychotic disturbances, neuropathological changes and brain imaging studies, atypical neuroleptics, psychopharmacology of schizophrenia, neuropeptide involvement, neurophysiology and information processing in schizophrenia. Also highlighted are the similarities between childhood developmental disorders and schizophrenia, as well as the relatively neglected area of biological factors in childhood psychosis and their predictive value in adult psychopathology. Psychiatrists, neuroscientists, pharmacologists, psychologists, physicians and general practitioners will find this authoritative state-of-the-art review important and informative reading.

The Spectrum of Psychotic Disorders
Author : Daryl Fujii,Iqbal Ahmed
Publisher : Cambridge University Press
Release Date : 2007-03-08
ISBN 10 : 113946213X
Pages : 329 pages
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The spectrum of psychotic disorders encompasses as many as 25 different etiologies, ranging from the primary psychoses through those secondary to medical conditions, drugs and medications, and sensory impairments. This 2007 book provides a one-stop, comprehensive review of these disorders and gives quick comparisons for diagnostic decision-making to help with difficult differential diagnoses. Every chapter is uniformly structured to show comparisons between each disorder of presentation, course, and underlying neuropathology. Evidence for each etiology is also rated, indicating the confidence level the reader can place in the current findings. The international team of authors also examines data supporting a unitary neurobiological model of psychosis and the hypothesis that psychosis is a neurobiological syndrome similar to aphasia or apraxia. This book represents a paradigm shift in understanding, classifying and diagnosing these disorders, providing directions for future research and treatment. It will be of great interest to psychiatrists and neuroscientists alike.

Neurobiology of Psychiatric Disorders
Author : Thomas E. Schlaepfer,Charles B. Nemeroff
Publisher : Elsevier
Release Date : 2012
ISBN 10 : 0444520023
Pages : 760 pages
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This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Social Cognition in Psychosis
Author : Eve Lewandowski,Ahmed A. Moustafa
Publisher : Academic Press
Release Date : 2019-05
ISBN 10 : 0128153156
Pages : 348 pages
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Social Cognition in Psychosis combines current research on phenotypes, neurobiology, and existing evidence on the assessment and treatment of various forms of psychoses. The book presents various treatment options, including assessment approaches, tools and training methods that aid in the rehabilitation of patients with psychotic disorders. Social cognition is a set of psychological processes related to understanding, recognizing, processing and appropriately using social stimuli in one's environment. Individuals with psychotic disorders consistently exhibit impairments in social cognition. As a result, social cognition has been an important target for intervention, with recent efforts trying to enhance early recovery among individuals with psychotic disorders. Provides an overview of social cognition in relation to various forms of psychotic disorders Includes assessment and treatment for social cognition dysfunction in psychoses Discusses the genetics and heritability theory of social cognitive dysfunction in psychosis Defines the neurobiology of social cognitive dysfunctions

Advances in the Neurobiology of Schizophrenia
Author : Johan A. den Boer,H. G. M. Westenberg,Herman M. Van Praag
Publisher : John Wiley & Son Limited
Release Date : 1995-07-11
ISBN 10 :
Pages : 469 pages
GET BOOK!

Recent years have witnessed major advances in the study of neuroscience which have increased our understanding of the relationship between cerebral processes and behavioural, cognitive and emotional disorders. This series aims to monitor important research developments in the field of biological psychiatry and their relevance to clinical practice. Since the 1950s there has been significant progress in our understanding of the neurobiology of schizophrenia. This important volume illustrates these new developments, particularly in terms of pharmacotherapeutics, pathogenesis and research methodology. Eminent scientists from around the world discuss conceptual issues, epidemiology, genetic analysis of psychotic disturbances, neuropathological changes and brain imaging studies, atypical neuroleptics, psychopharmacology of schizophrenia, neuropeptide involvement, neurophysiology and information processing in schizophrenia. Also highlighted are the similarities between childhood developmental disorders and schizophrenia, as well as the relatively neglected area of biological factors in childhood psychosis and their predictive value in adult psychopathology. Psychiatrists, neuroscientists, pharmacologists, psychologists, physicians and general practitioners will find this authoritative state-of-the-art review important and informative reading.