the developing microbiome

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The Developing Microbiome
Author : Erika Chiong Claud
Publisher : Academic Press
Release Date : 2020-05-23
ISBN 10 : 0128206179
Pages : 240 pages
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The Developing Microbiome: Lessons from Early Life focuses on the establishment of the microbiome in early life, exposing it as a key mediator of diseases and health throughout the lifecycle. The content presents a comprehensive view of the status of the field and draws real-world correlations to health and disease states. It collates the significant research being done in the pediatric microbiome research space and bridges the knowledge gap showing the factors that impact health and disease states throughout the lifecycle. Finally, it offers knowledge on how the microbiome is and can be manipulated to promote change. This is a perfect reference for both researchers and clinical scientists who are interested in the role of the infant microbiome in health and disease, as well as gastroenterologists and pediatricians looking to affect change in their patients. Provides comprehensive coverage of the factors that influence microbiome development Links research in pediatric patients to later life stages Examines increasing evidence on the impact of the microbiome beyond the gut

Adiposity
Author : Jan Gordeladze
Publisher : BoD – Books on Demand
Release Date : 2017-03-22
ISBN 10 : 953512997X
Pages : 296 pages
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This book is the second in a series of two, featuring the Adiposity - Omics and Molecular Understanding, serving as an introduction to modern views on how the adipocytes are reciprocally interacting with organ systems in order to explain the biology of the body's fat cells and how they are integrated with other organ systems, like muscle cells and the liver, in order to control the lipid metabolism in our bodies, to finally preserve a positive balance between white and brown/beige adipocyte tissues (WAT and BAT). The understanding of the "omics" of obesity will therefore enable clinicians and researchers to better pursue the untoward incidents of metabolic deviations from a defined and health-bringing homeostasis, with fully responding WAT and BAT, being able to preserve a healthy balance between fat-producing and fat-metabolizing tissues for the benefit of the host, and thus longevity (optimal health with healthy, well-functioning organ systems) throughout a lifetime.

Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications
Author : Joel Faintuch,Salomao Faintuch
Publisher : Academic Press
Release Date : 2019-01-03
ISBN 10 : 0128152508
Pages : 504 pages
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Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike. Provides comprehensive coverage on diagnosis, therapy, pharmacotherapy and disease prevention in context of the microbiome and metabolome Focuses on the proposed physiological or pathological conditions Presents an up-to-date, useful reference

The Microbiome in Health and Disease
Author : N.A
Publisher : Academic Press
Release Date : 2020-05-29
ISBN 10 : 0128200014
Pages : 520 pages
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The Microbiome in Health and Disease, Volume 171 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Microbiome in health and disease, CNS development and microbiome in infants, A gut feeling in ALS, Microbiome (Virome) and virus infection, Bugs and Drugs: microbiome in medicine metabolism, Immunity, T cells, and microbiome, Salmonella (Bacterial) infection and cancer: of mice and men, and many other highly researched topics. Provides a novel theme and multiple disciplinary topics of microbiome research in basic and translational studies Presents an updated collection on bacteria, virus, fungi and their interactions in microbiome Includes a timely discussion on the tools and methods used for modeling and analysis of microbiome data

The Human Microbiome, Diet, and Health
Author : Food Forum,Food and Nutrition Board,Institute of Medicine
Publisher : National Academies Press
Release Date : 2013-02-27
ISBN 10 : 030926586X
Pages : 161 pages
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The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.

Skin Microbiome Handbook
Author : Nava Dayan
Publisher : John Wiley & Sons
Release Date : 2020-08-11
ISBN 10 : 1119593042
Pages : 432 pages
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The idea to compile and edit the book is the result of over a decade of work by the editor, Dr. Nava Dayan, on various projects related to skin barrier, innate immunity, microbiome, developing products, testing methods and paths of products to the market, both for pharmaceutical and the cosmetic industries. The book is a summary of current status of knowledge, research tools and approaches in skin microbiome, in health and disease. It contains the following categories: healthy skin microbiome and oral-skin interaction, skin microbiome observational research, skin microbiome in disequilibrium and disease, skin’s innate immunity, testing and study design, regulatory and legal aspects for skin microbiome related products. The 18 chapters of the book are written by carefully selected leaders in the academia, industry exhibiting extensive experience and understanding in the areas of interest.

Milk, Mucosal Immunity and the Microbiome
Author : Pearay L. Ogra,W. Allan Walker,Bo Lönnerdal
Publisher : N.A
Release Date : 2020
ISBN 10 : 3318066850
Pages : 329 pages
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"This publication covers the 94th Nestle Nutritional Institute Workshop, which was designed to provide a comprehensive overview on the latest human milk research and its role in modulating mucosal immunity, the microbiome, and its impact on the neonate. This publication should provide scientific support to anyone seeking a deeper understanding of human milk and its immunological properties, and enlarge the knowledge of those who specialize in human milk research"--

COPD
Author : Cormac McCarthy
Publisher : BoD – Books on Demand
Release Date : 2018-02-21
ISBN 10 : 9535137824
Pages : 162 pages
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Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide and is estimated to become the third most common cause of death over the next decade. The knowledge of COPD pathogenesis and the disease course has greatly improved this progression in understanding and continues to have significant implications in the management of this condition. Novel areas of interest in COPD pathogenesis include further development of animal models, a better understanding of the genetics and epigenetics, the role of the microbiome, and an increasing appreciation of the associated comorbidities. This book intends to provide the reader with a brief overview of these topics and also provide an in-depth review of the current nonpharmacological clinical approaches to managing patients with COPD.

The Gut-Brain Axis
Author : Niall Hyland,Catherine Stanton
Publisher : Academic Press
Release Date : 2016-05-13
ISBN 10 : 0128025441
Pages : 508 pages
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The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. Focuses on specific areas in which the microbiota has been implicated in gut-brain communication Examines common mechanisms and pathways by which the microbiota may influence brain and behavior Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior

The Microbiome and the Brain
Author : David Perlmutter
Publisher : CRC Press
Release Date : 2019-12-06
ISBN 10 : 1351235680
Pages : 214 pages
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Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

Gastroenterology and Nutrition
Author : Josef Neu
Publisher : Elsevier Health Sciences
Release Date : 2018-07-06
ISBN 10 : 0323568459
Pages : 355 pages
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Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today’s practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient. Stay fully up to date in this fast-changing field with Gastroenterology and Nutrition, 3rd Edition. Emerging knowledge about the basic developmental physiology of upper intestinal motility as it relates to reflux and feeding tolerance, and immaturities in motility by altering composition of feedings and pharmacologic means. New content on genetics and pharmacology, the role of inflammation in systemic diseases in other organs as well as necrotizing enterocolitis, optimizing administration of lipids to preterm infants, and administering lipids to infants who are at high risk for complications secondary to suboptimal lipid therapies. Current coverage of the composition of human milk and clinical trials that address the efficacy of donor milk in comparison to formula and own mother’s milk. Consistent chapter organization to help you find information quickly and easily. The most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care. Purchase each volume individually, or get the entire 7-volume set! Gastroenterology and Nutrition Hematology, Immunology and Genetics Hemodynamics and Cardiology Infectious Disease and Pharmacology New Volume! Nephrology and Fluid/Electrolyte Physiology Neurology The Newborn Lung

The Microbiome and the Brain
Author : David Perlmutter
Publisher : CRC Press
Release Date : 2019-12-06
ISBN 10 : 1351235680
Pages : 214 pages
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Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

The Chemistry of Microbiomes
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable
Publisher : National Academies Press
Release Date : 2017-07-19
ISBN 10 : 0309458390
Pages : 132 pages
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The 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.

Microbiota in health and disease: from pregnancy to childhood
Author : Pamela D. Browne,Eric Claassen,Michael D. Cabana
Publisher : Wageningen Academic Publishers
Release Date : 2017-07-20
ISBN 10 : 9086868398
Pages : 344 pages
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This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant’s gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system. The book discusses a range of infant and childhood diseases that are associated with microbial changes or dysbiosis, such as gastrointestinal disorders, allergic diseases, autoimmune disorders and respiratory disorders. Additionally mechanisms by which microbial dysbiosis may influence behaviour in infants are discussed. Other topics include the use of current tools in molecular microbiology for microbiota-related research and clinical practice. In the management of particular paediatric disorders, the potential of microbial manipulation with pre- and probiotics during infancy and childhood is increasingly being investigated. This book presents the evidence supporting their use in practice and reviews safety aspects. Microbiota in health and disease: from pregnancy to childhood has the ambition to provide the reader with an overview of the most recent and stunning advances in the field of infant and child microbiota and their role in health, disease and prevention. As such, it is an excellent resource for health care professionals, students and researchers in the field of life sciences.

The Gut Microbiome
Author : Gyula Mozsik
Publisher : BoD – Books on Demand
Release Date : 2016-11-02
ISBN 10 : 9535127500
Pages : 112 pages
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In the last decades, the importance of gut microbiome has been linked to medical research on different diseases. Developments of other medical disciplines (human clinical pharmacology, clinical nutrition and dietetics, everyday medical treatments of antibiotics, changes in nutritional inhabits in different countries) also called attention to study the changes in the gut microbiome. This book contains five excellent review chapters in the field of gut microbiome, written by researchers from the USA, Canada, China, and India. These chapters present a critical review about some clinically important changes in the gut microbiome in the development of some human diseases and therapeutic possibilities (liver disease, cardiovascular diseases, brain diseases, gastrointestinal diseases). The book brings to attention the essential role of gut microbiome in keeping our life healthy. This book is addressed to experts of microbiology, podiatrists, gastroenterologists, internists, nutritional experts, cardiologists, basic and clinical researchers, as well as experts in the field of food industry.

Anti-cancer Drugs
Author : Jasna Bankovic
Publisher : BoD – Books on Demand
Release Date : 2016-12-07
ISBN 10 : 9535128132
Pages : 196 pages
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We are in constant search for new therapeutic options to cure cancer. In this book, you can find out how scientists throughout the world deal with this problem. Readers will learn how to engage nature, chemical synthesis, and cell machinery to design new anticancer agents. Nature has already been very generous in providing us different compounds which are in widespread application. Starting from these resources, various synthetic processes are applied to create synthetic drugs which can be then obtained in large quantities. Also, the cell by itself provides different possibilities to meet the constantly increasing requirements for successful therapy. Explore the book and find out what are the new ways to fight cancer.

Microbiomics
Author : N.A
Publisher : Academic Press
Release Date : 2020-02-21
ISBN 10 : 0128172827
Pages : 392 pages
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Microbiomics: Dimensions, Applications, and Translational Implications of Human and Environmental Microbiome Research describes a new, holistic approach to microbiomics. International experts provide in-depth discussion of current research methods for studying human, environmental, viral and fungal microbiomes, as well as the implications of new discoveries for human health, nutrition, disease, cancer research, probiotics and in the food and agricultural industries. Distinct chapters covering culturomics and sub-microbiomes, such as the viriome and mycetobiome, provide an integrative framework for the expansion of microbiomics into new areas of application, as well as crosspollination between research areas. Detailed case studies include the use of microbiomics to develop natural products with antimicrobial properties, microbiomic enhancements in food and beverage technology, microbes for bioprotection and biopreservation, microbial tools to reduce antibiotic resistance, and maintenance and cultivation of human microbial communities. Provides an integrated approach for realizing the potential of microbiomics across the life, environmental, food and agricultural sciences Includes thorough analysis of human, environmental, viral and mycetol microbiomes, as well as methods and technology for identifying microbiotes Features chapter contributions from international leaders in microbiomic methods, technology and applications

Human Microbiota in Health and Disease
Author : Bryan Tungland
Publisher : Academic Press
Release Date : 2018-05-25
ISBN 10 : 0128146508
Pages : 680 pages
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Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease

Avery's Diseases of the Newborn E-Book
Author : Christine A. Gleason,Sherin Devaskar
Publisher : Elsevier Health Sciences
Release Date : 2011-08-12
ISBN 10 : 1455727148
Pages : 1520 pages
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Avery’s Diseases of the Newborn, edited by Christine A. Gleason and Sherin U. Devaskar, is a practical, clinical reference for diagnosing and managing of all the important diseases affecting newborns. Thoroughly revised by a team of new editors, this edition provides new perspectives and updated coverage of genetics, nutrition, respiratory conditions, MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and more. This authoritative reference is ideal as a clinical resource or subspecialty review tool. Treat newborns effectively with focused coverage of diagnosis and management, including pertinent developmental physiology and the pathogenesis of neonatal problems. Meet every challenge you face in neonatology with Avery’s authoritative, comprehensive clinical resource and subspecialty review tool. Navigate quickly and easily with extensive cross-referencing throughout the organ-related sections. Stay current with coverage of hot topics including MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and the developing intestinal microbiome. Tap into the fresh perspectives of new editors who provide extensive updates throughout, particularly on genetic and respiratory disorders. Apply the latest nutritional findings with thorough discussions of this valuable information in the more comprehensive nutrition section. Master the fundamentals of neonatology through the greater emphasis on developmental biology and pathobiology.

The Microbiome Diet
Author : Raphael Kellman
Publisher : Da Capo Lifelong Books
Release Date : 2014-07-01
ISBN 10 : 0738217662
Pages : 272 pages
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The groundbreaking program that connects the microbiome and gut health to healthy weight loss, complete with a 3-phase plan and recipes Cutting-edge science has shown that the microbiome is the key to overall mental and physical health--and the secret behind healthy, sustainable weight loss. Drawing on nearly two decades of experience as a specialist in functional medicine and intestinal health, Dr. Raphael Kellman has developed the first diet based on these scientific breakthroughs. Offering a proven program to heal your gut and reset your metabolism, along with meal plans and 50 delicious chef-created recipes, The Microbiome Diet is the key to safe, sustainable weight loss and a lifetime of good health. "Dr. Kellman masterfully presents a life enhancing, actionable plan based on this emerging science in a way that is user-friendly, for all of us." --Dr. David Perlmutter, New York Times bestselling author of Grain Brain