tailor made polysaccharides in biomedical applications

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Tailor-Made Polysaccharides in Biomedical Applications
Author : Amit Kumar Nayak,Md Saquib Hasnain,Tejraj Aminabhavi
Publisher : Academic Press
Release Date : 2021-03-01
ISBN 10 : 0128213566
Pages : 370 pages
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Tailor-Made Polysaccharides in Biomedical Applications provides extensive details on the vital precepts, basics and fundamental aspects of tailored polysaccharides in pharmaceuticals and biotechnologicals. The utilization of natural polymeric excipients in numerous healthcare applications demands the replacement of synthetic polymers with natural ones due to their biocompatibility, biodegradability, economic extraction and availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and can tender an incessant supply of raw materials. This book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to biomedical researchers, chemical engineers, regulatory scientists, and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in biomedical applications. Provides methodologies on the design, development and selection of tailor-made polysaccharides in biomedical applications for particular therapeutic applications Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides Discusses regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

Functional Polysaccharides for Biomedical Applications
Author : Sabyasachi Maiti,Sougata Jana
Publisher : Woodhead Publishing
Release Date : 2019-06-11
ISBN 10 : 0081025564
Pages : 526 pages
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Functional Polysaccharides for Biomedical Applications examines the fundamentals and properties of these natural materials and their potential biomedical applications. With an emphasis on therapeutic and sensing applications, the book also reviews how polysaccharides can be modified for tissue engineering applications. Sections discuss the basics of polysaccharides, give an overview of the potential applications, look at novel materials and technologies for use in tissue regeneration and therapeutics, and detail current biomedical applications. With a strong focus on materials, engineering and applications, this book is a valuable resource for those with an interest in harnessing the biomedical potential of natural polymers. Describes strategies for developing polysaccharides-based biomedical devices Illustrates concepts and encompasses scope for clinical development Provides advanced and comprehensive information on biomedical constructs

Natural Polysaccharides in Drug Delivery and Biomedical Applications
Author : Md Saquib Hasnain,Amit Kumar Nayak
Publisher : Academic Press
Release Date : 2019-07-23
ISBN 10 : 0128170565
Pages : 654 pages
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Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field. Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications

Biomedical Applications of Hydrogels Handbook
Author : Raphael M. Ottenbrite,Kinam Park,Teruo Okano
Publisher : Springer Science & Business Media
Release Date : 2010-09-05
ISBN 10 : 9781441959195
Pages : 432 pages
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Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.

Polysaccharide Based Graft Copolymers
Author : Susheel Kalia,M.W. Sabaa
Publisher : Springer Science & Business Media
Release Date : 2013-05-23
ISBN 10 : 3642365663
Pages : 353 pages
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Renowned experts give all essential aspects of the techniques and applications of graft copolymers based on polysaccharides. Polysaccharides are the most abundant natural organic materials and polysaccharide based graft copolymers are of great importance and widely used in various fields. Natural polysaccharides have recently received more attention due to their advantages over synthetic polymers by being non-toxic, biodegradable and available at low cost. Modification of polysaccharides through graft copolymerization improves the properties of polysaccharides. Grafting is known to improve the characteristic properties of the backbones. Such properties include water repellency, thermal stability, flame resistance, dye-ability and resistance towards acid-base attack and abrasion. Polysaccharides and their graft copolymers find extensive applications in diversified fields. Applications of modified polysaccharides include drug delivery devices, controlled release of fungicides, selective water absorption from oil-water emulsions, purification of water etc.

Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications
Author : Hriday Bera,Chowdhury Mobaswar Hossain,Sudipta Saha
Publisher : Academic Press
Release Date : 2021-01-18
ISBN 10 : 0128208759
Pages : 628 pages
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Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications presents a clear and detailed body of information on biopolymer chemistry and polymer sciences in drug delivery. The book covers the recently reported nanomaterials consisting of biopolymers such as polysaccharides (i.e., plant, animal, bacteria, algae and fungi-derived) and proteins in terms of their structures, synthetic protocols and characterizations. In addition, their applications as therapeutic drug and gene delivery carriers and in other biomedical fields are reviewed. This book compiles chapters contributed by internationally renowned scholars working in biopolymer-based nanomaterials, offering a wide vision on the new and ongoing potential of different biopolymeric nanomaterials. The information related to concepts, design protocols and applications of biopolymer-based nanoplatforms is presented here, with detailed chapters on Pectin based nanomaterials, Konjac glucomannan based nanomaterials, Guar gum-based nanomaterials, tailor-made gum Arabic based nanomaterials, among others. Such systems are widely being used as functional materials for drug delivery and other therapeutic applications. Provides a critical and detailed examination in the recent development of biopolymer-based nanomaterials Focuses on modified biopolymer-based, diverse cutting-edge techniques in drug delivery and biomedical applications Assesses the opportunities and challenges of biopolymer-based nano-carriers in pharmaceutical and biomedical fields

Natural Polysaccharides in Drug Delivery and Biomedical Applications
Author : Md Saquib Hasnain,Amit Kumar Nayak
Publisher : Academic Press
Release Date : 2019-07-23
ISBN 10 : 0128170565
Pages : 654 pages
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Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field. Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications

Polysaccharides
Author : Severian Dumitriu
Publisher : CRC Press
Release Date : 1998-05-12
ISBN 10 : 9780849335693
Pages : 1176 pages
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Offers comprehensive coverage of the structural characterization of polysaccharides-emphasizing commercially available and potential exopolysaccharides as well as new applications. Presents the major chemical and physical properties of polysaccharides and derivatives.

Polysaccharide Carriers for Drug Delivery
Author : Sabyasachi Maiti,Sougata Jana
Publisher : Woodhead Publishing
Release Date : 2019-06-14
ISBN 10 : 0081025548
Pages : 802 pages
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Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter. Focuses on biopolysaccharide-based, distinct approaches for drug delivery applications Illustrates new concepts and highlights future scope for clinical development Provides comprehensive, up-to-date information on different aspects of drug delivery technology

Polysaccharide Hydrogels
Author : Pietro Matricardi,Franco Alhaique,Tommasina Coviello
Publisher : CRC Press
Release Date : 2016-01-05
ISBN 10 : 9814613622
Pages : 540 pages
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Hydrogels are an emerging area of interest in medicine as well as pharmaceutics, and their physico-chemical characterization is fundamental to their practical applications. Compared with synthetic polymers, polysaccharides that are widely present in living organisms and come from renewable sources are extremely advantageous for hydrogel formation. Furthermore, polysaccharides are usually non-toxic and biocompatible and show a number of peculiar physico-chemical properties that make them suitable for a wide variety of biomedical applications. This book bridges the gap between the preparation of hydrogels and their characterization techniques. It aims to offer a valid support that can help the readers find appropriate keys to open the doors to the complex world of polysaccharide hydrogels.

Biological Activities and Application of Marine Polysaccharides
Author : Emad Shalaby
Publisher : BoD – Books on Demand
Release Date : 2017-01-11
ISBN 10 : 9535128590
Pages : 328 pages
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Marine organisms have been under research for the last decades as a source for different active compounds with various biological activities and application in agriculture, pharmacy, medicine, environment, and industries. Marine polysaccharides from these active compounds are used as antibacterial, antiviral, antioxidant, anti-inflammation, bioremediations, etc. During the last three decades, several important factors that control the production of phytoplankton polysaccharides have been identified such as chemical concentrations, temperature, light, etc. The current book includes 14 chapters contributed by experts around the world; the chapters are categorized into three sections: Marine Polysaccharides and Agriculture, Marine Polysaccharides and Biological Activities, and Marine Polysaccharides and Industries.

Layer-by-Layer Films for Biomedical Applications
Author : Catherine Picart,Frank Caruso,Jean-Claude Voegel
Publisher : John Wiley & Sons
Release Date : 2014-12-22
ISBN 10 : 3527675884
Pages : 592 pages
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The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance. In the last 15 years the LbL technique has seen considerable developments and has now reached a point where it is beginning to find applications in bioengineering and biomedical engineering. The book gives a thorough overview of applications of the LbL technique in the context of bioengineering and biomedical engineering where the last years have witnessed tremendous progress. The first part familiarizes the reader with the specifics of cell-film interactions that need to be taken into account for successful application of the LbL method in biological environments. The second part focuses on LbL-derived small drug delivery systems and antibacterial agents, and the third part covers nano- and microcapsules as drug carriers and biosensors. The fourth and last part focuses on larger-scale biomedical applications of the LbL method such as engineered tissues and implant coatings.

Biopolymer-Based Composites
Author : Sougata Jana,Sabyasachi Maiti,Subrata Jana
Publisher : Woodhead Publishing
Release Date : 2017-06-15
ISBN 10 : 0081019157
Pages : 422 pages
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Biopolymer-Based Composites: Drug Delivery and Biomedical Applications presents a comprehensive review on recent developments in biopolymer-based composites and their use in drug delivery and biomedical applications. The information contained in this book is critical for the more efficient use of composites, as detailed up-to-date information is a pre-requirement. The information provided brings cutting-edge developments to the attention of young investigators to encourage further advances in the field of bio-composite research. Currently, biopolymers are being investigated for the design of various drug delivery and biomedical devices due to their non-toxic, biodegradable and biocompatible nature. Mostly, biopolymer-based solid orals, gels, hydrogel beads, and transdermal matrices have been designed in order to control drug/protein release in simulated bio-fluids. Presents the most updated information in the field of pharmaceutical and biological sciences Contains color figures and illustrations to help users understand key topics Useful guide for young researchers working towards new innovations Includes chapters covered by eminent scientists in the field

Biomedical Foams for Tissue Engineering Applications
Author : Paulo Netti
Publisher : Elsevier
Release Date : 2014-02-28
ISBN 10 : 0857097032
Pages : 446 pages
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Biomedical foams are a new class of materials, which are increasingly being used for tissue engineering applications. Biomedical Foams for Tissue Engineering Applications provides a comprehensive review of this new class of materials, whose structure can be engineered to meet the requirements of nutrient trafficking and cell and tissue invasion, and to tune the degradation rate and mechanical stability on the specific tissue to be repaired. Part one explores the fundamentals, properties, and modification of biomedical foams, including the optimal design and manufacture of biomedical foam pore structure for tissue engineering applications, biodegradable biomedical foam scaffolds, tailoring the pore structure of foam scaffolds for nerve regeneration, and tailoring properties of polymeric biomedical foams. Chapters in part two focus on tissue engineering applications of biomedical foams, including the use of bioactive glass foams for tissue engineering applications, bioactive glass and glass-ceramic foam scaffolds for bone tissue restoration, composite biomedical foams for engineering bone tissue, injectable biomedical foams for bone regeneration, polylactic acid (PLA) biomedical foams for tissue engineering, porous hydrogel biomedical foam scaffolds for tissue repair, and titanium biomedical foams for osseointegration. Biomedical Foams for Tissue Engineering Applications is a technical resource for researchers and developers in the field of biomaterials, and academics and students of biomedical engineering and regenerative medicine. Explores the fundamentals, properties, and modification of biomedical foams Includes intense focus on tissue engineering applications of biomedical foams A technical resource for researchers and developers in the field of biomaterials, and academics and students of biomedical engineering and regenerative medicine

Hydrogels and Biodegradable Polymers for Bioapplications
Author : Raphael M. Ottenbrite,American Chemical Society,Samuel J. Huang,Kinam Park
Publisher : Amer Chemical Society
Release Date : 1996
ISBN 10 :
Pages : 268 pages
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Examines the use of reversible hydrogels, stimuli-sensitive hydrogels, and in vivo applications of hydrogels. Discusses current issues in biodegradation, including controlled release from degradable matrices, degradation of synthetic materials in marine and soil environments, and time-related degradation of support devices and other applications of biomaterials. Reviews applications of biomaterials and hydrogels.

Polymeric Hydrogels as Smart Biomaterials
Author : Susheel Kalia
Publisher : Springer
Release Date : 2015-11-18
ISBN 10 : 3319253220
Pages : 234 pages
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This book is concerned with polymeric hydrogels, which are considered as one of the most promising types of new polymer-based materials. Each chapter in this book describes a selected class of polymeric hydrogels, such as superabsorbent hybrid nanohydrogels, conducting polymer hydrogels, polysaccharide-based or protein-based hydrogels, or gels based on synthetic polymers. In this way, the book also addresses some of the fascinating properties and applications of polymeric hydrogels: they are three-dimensional, hydrophilic, polymeric networks that can absorb, swell and retain large quantities of water or aqueous fluids. In combination with metal nanoparticles, nanofibrils or nanowhiskers, which may be embedded in the gels, they find widespread applications, ranging from agriculture, and waste water treatment, over electronics, to pharmaceutical and biomedical applications. Applications mentioned in this book include electro sensors, capacitors, electromechanical actuators, and even artificial muscles.

Extracellular Sugar-Based Biopolymers Matrices
Author : Ephraim Cohen,Hans Merzendorfer
Publisher : Springer
Release Date : 2019-07-02
ISBN 10 : 3030129195
Pages : 820 pages
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The extracellular matrix (ECM) is an acellular three-dimensional network composed of proteins, glycoproteins, proteoglycans and exopolysaccharides. It primarily serves as a structural component in the tissues and organs of plants and animals, or forms biofilms in which bacterial cells are embedded. ECMs are highly dynamic structures that undergo continuous remodeling, and disruptions are frequently the result of pathological processes associated with severe diseases such as arteriosclerosis, neurodegenerative illness or cancer. In turn, bacterial biofilms are a source of concern for human health, as they are associated with resistance to antibiotics. Although exopolysaccharides are crucial for ECM formation and function, they have received considerably little attention to date. The respective chapters of this book comprehensively address such issues, and provide reviews on the structural, biochemical, molecular and biophysical properties of exopolysaccharides. These components are abundantly produced by virtually all taxa including bacteria, algae, plants, fungi, invertebrates and vertebrates. They include long unbranched homopolymers (cellulose, chitin/chitosan), linear copolymers (alginate, agarose), peptoglycans such as murein, heteropolymers like a variety of glycosaminoglycans (hyaluronan, dermatan, keratin, heparin, Pel), and branched heteropolymers such as pectin and hemicellulose. A separate chapter is dedicated to modern industrial and biomedical applications of exopolysaccharides and polysaccharide-based biocomposites. Their unique chemical, physical and mechanical properties have attracted considerable interest, inspired basic and applied research, and have already been harnessed to form structural biocomposite hybrids for tailor-made applications in regenerative medicine, bioengineering and biosensor design. Given its scope, this book provides a substantial source of basic and applied information for a wide range of scientists, as well as valuable textbook for graduate and advanced undergraduate students.

Alginates in Drug Delivery
Author : Amit Kumar Nayak,Md Saquib Hasnain
Publisher : Academic Press
Release Date : 2020-07-23
ISBN 10 : 0128176415
Pages : 434 pages
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Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields Includes high quality illustrations, along with practical examples and research case studies Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

Natural and Synthetic Biomedical Polymers
Author : Sangamesh Kumbar,Cato Laurencin,Meng Deng
Publisher : Newnes
Release Date : 2014-01-21
ISBN 10 : 0123972906
Pages : 420 pages
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Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future

Advances in Sustainable Polymers
Author : Vimal Katiyar,Raghvendra Gupta,Tabli Ghosh
Publisher : Springer Nature
Release Date : 2019-11-05
ISBN 10 : 9813298049
Pages : 483 pages
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This book provides a systematic overview of the processing and applications of sustainable polymers. The volume covers recent advances in biomedical, food packaging, fuel cell, membrane, and other emerging applications. The book begins by addressing different sections of biomedical application including use of carbohydrate-based therapeutics, nanohybrids, nanohydrogels, bioresorbable polymers and their composites, polymer-grafted nanobiomaterials for biomedical devices and implants, nanofibres, and others. The second part of this book discusses various processing and packaging materials for food packaging applications. The last section discusses other emerging applications, including using microbial fuel cells for waste water treatment, microfluidic fuel cells for low power applications, among others. This volume will be relevant to researchers working to improve the properties of bio-based materials for their advanced application and wide commercialization.