| Author | : Stephen D. Meriney,Erika Fanselow |
| Publisher | : Academic Press |
| Release Date | : 2019-06-12 |
| ISBN 10 | : 0128153210 |
| Pages | : 528 pages |
Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic
| Author | : STEPHEN D.. FANSELOW MERINEY (ERIKA.),Erika Fanselow |
| Publisher | : Academic Press |
| Release Date | : 2019-06-15 |
| ISBN 10 | : 9780128153208 |
| Pages | : 550 pages |
Synaptic transmission is the process by which neurons communicate with one another at synapses, which is essential for normal function of the central and peripheral nervous systems. Synaptic dysfunction is linked to a number of conditions affecting the nervous system, including schizophrenia, Alzheimer's disease, Parkinson's disease, impairments in muscle control, and other neurological disorders. Synaptic Transmission is a comprehensive guide to the topic of neurotransmission, providing an in-depth discussion of many aspects of synapse structure and function, a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on the topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders, training future researchers and clinicians in this critical discipline. A comprehensive reference on synaptic structure, physiology, function, and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Chapters include references to primary scientific literature, relevant review articles, and books, many of which could be assigned as discussion material for courses focused on this topic
| Author | : T. W. Stone |
| Publisher | : Taylor & Francis |
| Release Date | : 1991 |
| ISBN 10 | : 9780850668285 |
| Pages | : 404 pages |
A collection of reviews on selected areas of synaptic transmission from neuroscientists in a number of areas of work in the nervous system and related disciplines. Five areas are covered - long-term potentiation, galanin, autonomic, opioids and 5-hydroxytryptamine.
| Author | : Joseph D. Robinson |
| Publisher | : Oxford University Press |
| Release Date | : 2001-05-17 |
| ISBN 10 | : 0198031459 |
| Pages | : 472 pages |
Synaptic transmission plays a central role in the nervous system as the mechanism that allows for chemical and electrical communication between cells and thus connects discrete elements into the functioning whole. This is a broad account of anatomical, biochemical, embryological, medical, pathological, pharmacological, and physiological studies on synaptic transmission during the hundred years beginning in 1890. During this century, the process of synaptic transmission came to be recognized not only as the most fundamental neurophysiological process, but also as a seat of pathological changes, and as the predominant site of action for drugs used to treat a wide range of psychiatric and neurological disorders. At the same time, research from these various disciplines was transformed into a new and unifying field, neuroscience. The course of these investigations reveals ingenious experiments, powerful new techniques, and imaginative insights. The author describes broadly who did what, when, where, and how (and, in cases where it is apparent, why) and uses experimental results and interpretations to display the evolutionary course to our current understanding of how nerve cells communicate: the basic principle of neural functioning. The book will be of interest to basic and clinical neuroscientists, pharmacologists, and physiologists, to historians and philosophers of the life sciences and medicine, and to their respective students.
| Author | : Stephen D. Meriney,Erika Fanselow |
| Publisher | : Academic Press |
| Release Date | : 2019-06-12 |
| ISBN 10 | : 0128153210 |
| Pages | : 528 pages |
Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic
| Author | : Frotscher,Misgeld |
| Publisher | : Birkhäuser |
| Release Date | : 2013-03-07 |
| ISBN 10 | : 3034891385 |
| Pages | : 324 pages |
Our knowledge of cholinergic synaptic transmission in the peripheral nervous system (PNS) has expanded enormously since the early 1930's, at which time O. Loewi discovered chemical neurotransmission through acetylcholine (ACh) and the pharmacological actions of ACh were described by H. Dale and his colleagues. Description of ACh's actions and receptors in various parts of the brain was followed by a detailed analysis of ACh's synthesis, release mechanism, removal from the synaptic cleft, modes of agonist-receptor interactions, properties of regulated conductances and of the pre-and postsynaptic modulation of cholinergic synapses. Our knowledge has been increasingly consolidat ing, leading us to the recent clarification of the structure of the periph eral nicotinic receptor-ion channel and its functional properties. It is appropriate to maintain the claim that the fundamentals of our under standing of synaptic transmission come from studies on cholinergic synapses in the PNS. Contrastingly, views held on the role of cholinergic synapses in the mammalian central nervous system (CNS) are extremely controversial, although it has been clear for some time that ACh is present in the brain. Illustrating this, no unanimous view is held on the role of nicotinic receptors in the CNS. There is one notable exception to this confusion: Studies begun by J. C. Eccles and associates in the 1960's and completed by D. R. Curtis and R. W.
| Author | : N.A |
| Publisher | : Elsevier |
| Release Date | : 1969 |
| ISBN 10 | : 9780080861562 |
| Pages | : 360 pages |
Mechanisms of Synaptic Transmission
| Author | : Jiajie Diao,Cong Ma |
| Publisher | : Frontiers Media SA |
| Release Date | : 2020-05-05 |
| ISBN 10 | : 2889636925 |
| Pages | : 329 pages |
| Author | : Menahem Segal,Harmen J. Krugers,Nicola Maggio |
| Publisher | : Frontiers E-books |
| Release Date | : |
| ISBN 10 | : 9782889191031 |
| Pages | : 329 pages |
Recently, several pioneering discoveries have identified new roles of stress and steroid hormones in modulating CNS functions. Specifically, glucocorticoids, mineralocorticoids, sex hormones and neurosteroids have been shown to affect synaptic receptors and ion channels and therefore regulate in a complex manner physiological processes ranging from homeostatic to cognitive functions. Likewise, in some disorders of the nervous system, steroid hormones have been shown to play different roles: either favoring or combating the disease process. In this Frontier Research Topic, we have put together leaders in the field to provide novel opinions on the effects of steroid hormones on synaptic transmission and plasticity from ion channels to pathophysiological processes. We expect critical reviews of the work that has been conducted recently in this area and enrich these discussions with the novel, exciting new findings.
| Author | : 廣川信隆 |
| Publisher | : Taylor & Francis |
| Release Date | : 1993 |
| ISBN 10 | : 9784762277498 |
| Pages | : 335 pages |
| Author | : Maria Elisa Calcagnotto,Alberto A. Rasia-Filho,Idan Segev |
| Publisher | : Frontiers Media SA |
| Release Date | : 2019-06-21 |
| ISBN 10 | : 2889458911 |
| Pages | : 329 pages |
| Author | : Janos Szentagothai |
| Publisher | : N.A |
| Release Date | : 1958 |
| ISBN 10 | : |
| Pages | : 309 pages |
| Author | : Armin Kargol |
| Publisher | : Morgan & Claypool Publishers |
| Release Date | : 2019-12-13 |
| ISBN 10 | : 1643277561 |
| Pages | : 106 pages |
All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists’ point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.
| Author | : M. Baudry,Joel L. Davis,Richard F. Thompson |
| Publisher | : MIT Press |
| Release Date | : 2000 |
| ISBN 10 | : 9780262024600 |
| Pages | : 335 pages |
This book, a follow-up to the editors' Synaptic Plasticity (MIT Press,1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Many neurons exhibit plasticity; that is, they can change structurally or functionally, often in a lasting way. Plasticity is evident in such diverse phenomena as learning and memory, brain development, drug tolerance, sprouting of axon terminals after a brain lesion, and various cellular forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression. This book, a follow-up to the editors' Synaptic Plasticity (MIT Press, 1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Contributors Yael Amitai, Michel Baudry, Theodore W. Berger, Pierre-Alain Buchs, A.K. Butler, Franck A. Chaillan, Gilbert A. Chauvet, Marie-Françoise Chesselet, Barry W. Connors, Taraneh Ghaffari, Jay R. Gibson, Ziv Gil, Michel Khrestchatisky, Dietmar Kuhl, Carole E. Landisman, Gilles Laurent, Jim-Shih Liaw, David J. Linden, Katrina MacLeod, Henry Markram, W.V. Morehouse, Dominique Muller, J.A. Napieralski, Santiago Rivera, François S. Roman, Bernard Soumireu-Mourat, Oswald Steward, Mark Stopfer, F.G. Szele, Richard F. Thompson, Nicolas Toni, Bernard Truchet, Misha Tsodyks, K. Uryu, Ascher Uziel, Christopher S. Wallace, Yun Wang, Michael Wehr, Paul F. Worley, Xiaping Xie
| Author | : Zach W. Hall,John G. Hildebrand,Edward A. Kravitz |
| Publisher | : N.A |
| Release Date | : 1974 |
| ISBN 10 | : |
| Pages | : 615 pages |
| Author | : Michael E. Selzer,Michael Selzer,Stephanie Clarke,Leonardo Cohen,Pamela Duncan,Fred Gage |
| Publisher | : Cambridge University Press |
| Release Date | : 2006-02-16 |
| ISBN 10 | : 9780521856416 |
| Pages | : 724 pages |
Covers the basic sciences relevant to recovery of function following injury to the nervous system.
"For both seasoned neurobiologists and interested newcomers to the field, this book is a worthwhile introduction to the wonders of synapses and the many opportunities for future study that they offer." -- Science
| Author | : Mark L. Latash |
| Publisher | : Human Kinetics |
| Release Date | : 2008 |
| ISBN 10 | : 9780736063678 |
| Pages | : 427 pages |
With eight new chapters and 130 pages of fresh material, this second edition covers a wide range of topics, including movement disorders and current theories of motor control and co-ordination.
| Author | : John I. Hubbard,Rodolfo Riascos Llinás,David M. J. Quastel |
| Publisher | : N.A |
| Release Date | : 1969 |
| ISBN 10 | : |
| Pages | : 372 pages |
| Author | : Ruth Heidelberger,M. Neal Waxham,John H. Byrne,James L. Roberts |
| Publisher | : Academic Press |
| Release Date | : 2009-01-27 |
| ISBN 10 | : 9780080920832 |
| Pages | : 656 pages |
An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease. • Written and edited by leading experts in the field, the second edition completely and comprehensively updates all chapters of this unique textbook • Discusses emerging new understanding of non-classical molecules that affect neuronal signaling • Full colour, professional graphics throughout • Includes two new chapters: Information Processing in Neural Networks - describes the principles of operation of neural networks and the key circuit motifs that are common to many networks in the nervous system. Molecular and Cellular Mechanisms of Neurodegenerative Disease - introduces the progress made in the last 20 years in elucidating the cellular and molecular mechanisms underlying brain disorders, including Amyotrophic Lateral Sclerosis (ALS), Parkinson disease, and Alzheimer’s disease.