Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus. Discusses heterogeneity of topics and audience, from basic immunology to clinical aspects and therapeutics Provides novel lines of investigation and supports the management of patients requiring novel therapeutic approaches Presents a deeper knowledge on SS clinical management as well as on immunological aspects possibly leading to new lines of investigation Offers a bridge between the clinician and the scientist, and vice versa Provides the reader with most recent and relevant updates due to the novelty of topics
Written by leaders in the field and edited by Dr. Frederick Vivino, this concise, practical resource provides best practices for the diagnosis and treatment of Sjogren’s Syndrome. It offers a concise overview of this complex autoimmune disease, including information on specific clinical settings, childhood Sjogren’s, extra-oral and extra-ocular manifestations, vaccine safety, complementary and alternative medicine, and much more. Provides concise, clinically focused content with an emphasis on diagnosis and treatment. Includes Sjogren's Syndrome Foundation Practice Guidelines and the most recent ACR-EULAR classification criteria. Consolidates today's available information and experience in this important area into one convenient resource.
Afflicting one in seventy Americans, Sjögren's syndrome is an autoimmune disease that commonly causes dryness of the eyes, mouth, and nose, and that can lead to complications including profound fatigue, depression, and lymphoma. While there is no cure for Sjögren's, much can be done to alleviate the suffering of patients. This extensively revised handbook offers everything you need to know to cope with this disease. The Sjögren's Book, Fourth Edition is a comprehensive and authoritative guide, produced by the Sjögren's Syndrome Foundation and its medical advisors and edited by physician Daniel J. Wallace, a leading authority on autoimmune disorders. This expanded edition provides readers with the best medical and practical information on this disorder, bringing together the current thinking about Sjögren's in an easily readable and understandable book, with an entirely new section on lifestyle issues aimed at improving the quality of life for Sjögren's sufferers. With more than thirty chapters written by leading experts, the handbook illuminates the major clinical aspects of the syndrome and is loaded with practical tips and advice. Indeed, it offers a wide-ranging look at the many faces of Sjögren's, covering diagnosis, the various organ systems that can be affected, the possible psychological problems, and the many treatment options, as well as a concluding chapter listing the web, print, and media resources available. It is a valuable aid that patients can use while discussing their illness with their physician and an excellent resource for family members. And because Sjögren's is greatly underdiagnosed, this handbook is a particularly valuable resource for healthcare professionals. Recognized as the bible for Sjögren's suffers, this reliable and informative guide is the first place for patients to look when they have questions about this little known but serious chronic disease.
This second edition of 'Oral and Maxillofacial Medicine' continues to present the basics of the speciality in an accessible and digestible format. The book offers sound guidance on the whole range of common and potentially serious disorders that are routinely encountered in clinical practice.
Afflicting nearly four million Americans, Sjogren's syndrome is an autoimmune disease that commonly causes dryness of the eyes, mouth, and nose, and that can lead to complications including profound fatigue, depression, and lymphoma. While there is no cure for Sjogren's, much can be done to alleviate the suffering of patients. This extensively revised handbook offers everything you need to know to cope with this disease. The New Sjogren's Syndrome Handbook, Third Edition is a comprehensive and authoritative guide, produced by the Sjogren's Syndrome Foundation and its medical advisors and edited by physician Daniel J. Wallace, a leading authority on auto-immune disorders. This expanded edition provides readers with the best medical and practical information on this disorder, bringing together the current thinking about Sjogren's in an easily readable and understandable book. The handbook illuminates the major clinical aspects of the syndrome and is loaded with practical tips and advice to assist those seeking information. Indeed, it offers a wide-ranging look at the many faces of Sjogren's, covering diagnosis, the various organ systems that can be affected, the possible psychological problems, and the many treatment options, as well as an appendix listing the resources available for patients with the disease. It is a valuable aid that patients can use while discussing their illness with their physician and an excellent resource for family members. And because Sjogren's is greatly underdiagnosed, this handbook is a particularly valuable resource for healthcare professionals. The most reliable and informative guide available, The New Sjogren's Syndrome Handbook, Third Edition is the first place for patients to look when they have questions about this little known but serious chronic disease.
A comprehensive guide defining the autoimmune disease known as Sjogren's syndrome, its symptoms, treatment options, and information on living with the disease.
The key knowledge assembled in this book comprises today’s most comprehensive resource on Sjögren’s syndrome. Sjögren’s patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others. This practical clinical resource begins with an overview of Sjögren’s myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria. The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics. The third section is devoted to clinical manifestations and therapeutic considerations. It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book’s contributors. With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets. Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren’s patients and physicians.
|Author||: David A. Sullivan,Darlene A. Dartt,Michele A. Meneray|
|Publisher||: Springer Science & Business Media|
|Release Date||: 2012-12-06|
|ISBN 10||: 1461553598|
|Pages||: 1051 pages|
During the past two decades, a significant international research effort has been di rected toward understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays an essential role in maintaining corneal and conjunctival integrity, protecting against microbial challenge, and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in countless individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perfo ration of the cornea, an increased incidence of infectious disease, and, potentially, pro nounced visual disability and blindness. To promote further progress in this field of vision research, the Second International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance was held at the Southampton Princess Resort in Bermuda November 16-19, 1996. This conference was organized and directed by David A. Sullivan, Ph. D. , codirected by Darlene A. Dartt, Ph. D. , and Michele A. Meneray, Ph. D. , and sponsored by the Schepens Eye Research Institute (Boston, MA), an affiliate of Harvard Medical School. The meeting was designed to assess critically the current knowledge and "state of the art" research on the structure and function of lacrimal tissue, tears, and the ocular sur face in both health and disease.
Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.
In this book, experts provide a comprehensive review of current knowledge regarding nutrition and dietary management for the complex set of rheumatic conditions. Within the disease-specific chapters, the authors present a historical perspective, a discussion of the major clinical features, current management and treatment, a review of the literature related to nutritional status and diet, and dietary recommendations, based on current scientific evidence. The field of rheumatic diseases includes a wide variety of pathologic processes. This book will greatly benefit physicians specializing in internal medicine, family practice, and rheumatology.