sex gender and epigenetics

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Exploring the Biological Contributions to Human Health
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publisher : National Academies Press
Release Date : 2001-07-02
ISBN 10 : 9780309132978
Pages : 288 pages
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It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Gender Medicine
Author : Marek Glezerman
Publisher : Duckworth Overlook
Release Date : 2017-09-21
ISBN 10 : 9780715652244
Pages : 288 pages
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Despite the fact that cultural differences between genders are becoming obsolete, the differences between male and female bodies are nevertheless very real, and go well beyond the obvious sexual and reproductive variances: men and women absorb medication, feel pain, and even display early symptoms of heart attacks differently. And yet the medical establishment treats male and female patients as though their needs were identical. In fact, medical research is still done predominately on men, and the results applied to the treatment of women. This is clearly problematic, and Gender Medicine calls for the reform of attitudes and practices, for all of us: GP and surgeon, researcher and patient.

Evolution's Rainbow
Author : Joan Roughgarden
Publisher : Univ of California Press
Release Date : 2013-09-14
ISBN 10 : 0520957970
Pages : 496 pages
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In this innovative celebration of diversity and affirmation of individuality in animals and humans, Joan Roughgarden challenges accepted wisdom about gender identity and sexual orientation. A distinguished evolutionary biologist, Roughgarden takes on the medical establishment, the Bible, social science—and even Darwin himself. She leads the reader through a fascinating discussion of diversity in gender and sexuality among fish, reptiles, amphibians, birds, and mammals, including primates. Evolution's Rainbow explains how this diversity develops from the action of genes and hormones and how people come to differ from each other in all aspects of body and behavior. Roughgarden reconstructs primary science in light of feminist, gay, and transgender criticism and redefines our understanding of sex, gender, and sexuality. Witty, playful, and daring, this book will revolutionize our understanding of sexuality. Roughgarden argues that principal elements of Darwinian sexual selection theory are false and suggests a new theory that emphasizes social inclusion and control of access to resources and mating opportunity. She disputes a range of scientific and medical concepts, including Wilson's genetic determinism of behavior, evolutionary psychology, the existence of a gay gene, the role of parenting in determining gender identity, and Dawkins's "selfish gene" as the driver of natural selection. She dares social science to respect the agency and rationality of diverse people; shows that many cultures across the world and throughout history accommodate people we label today as lesbian, gay, and transgendered; and calls on the Christian religion to acknowledge the Bible's many passages endorsing diversity in gender and sexuality. Evolution's Rainbow concludes with bold recommendations for improving education in biology, psychology, and medicine; for democratizing genetic engineering and medical practice; and for building a public monument to affirm diversity as one of our nation's defining principles.

Sex and Gender Differences in Pharmacology
Author : Vera Regitz-Zagrosek
Publisher : Springer Science & Business Media
Release Date : 2012-10-02
ISBN 10 : 3642307256
Pages : 602 pages
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A trailblazing assessment of sex and gender differences in reactions to drug therapy, this volume reflects the topic’s growing recognition. Analyses by international experts on both pharmacokinetics and drug development are informed by an extensive data set.

Sex Differences in Neurology and Psychiatry
Author : N.A
Publisher : Elsevier
Release Date : 2020-09-30
ISBN 10 : 0444641246
Pages : 476 pages
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Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

The Plasticity of Sex
Author : Marianne J. Legato
Publisher : Academic Press
Release Date : 2020-05-19
ISBN 10 : 0128159693
Pages : 318 pages
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The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior provides a comprehensive view on the development of human sexuality. As there has been a crescendo of interest over the past several decades about the nature and diversity of human sexuality, this reference brings the evidence-based research into one place. The emergence of issues surrounding gender identity, genital ambivalence and the transition from one sex to another is striking, with the public and treating physicians alike clamoring for an evidence-based, comprehensive treatment of human sexuality and all its variations. This is a must-have reference for biomedical researchers in endocrinology, neuroscience, development biology, medical students, residents, and practicing physicians from all medical areas. Discusses the role of biology in gender identity from research in genetics, endocrinology and neuroscience Addresses important health disparities and how to address them when treating the transgender patient Reviews evidence-based information on the biological basis and impact of environmental and hormonal factors at different life stages Outlines schema for treating variations in the sexuality and sexual function of the individual patient

Bridging Gaps Between Sex and Gender in Neurosciences
Author : Annie Duchesne,Meng-Chuan Lai,Gillian Einstein,Belinda Pletzer,Marina A. Pavlova
Publisher : Frontiers Media SA
Release Date : 2020-07-14
ISBN 10 : 2889638650
Pages : 329 pages
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The International Society for Gender Medicine
Author : Marianne J. Legato,Marek Glezerman
Publisher : Academic Press
Release Date : 2017-08-24
ISBN 10 : 0128118512
Pages : 160 pages
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The International Society for Gender Medicine: History and Highlights is about a major step in the improvement of quality in medicine, namely the long overdue understanding that women are different from men in every system of the body and may require different approaches in diagnosis and treatment. This is not a textbook, nor is it a scientific publication. It is the story of the International Society for Gender Medicine (IGM) as soon through the eyes of 12 pioneers of Gender and Sex Specific Medicine (GSSM) from seven countries, five of whom were the founds of IGM in 2006. It describes the development of this new science in the respective countries and academic environments of the authors, their very personal experience while promoting, and implementing their vision of GSSM, their frustrations, successes, and achievements. The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender and sex. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, cancer, osteoporosis, diabetes, obesity, and infectious diseases. This book is essential reading for all researchers, graduate students, practitioners, and anyone interested in this diverse and thriving field. From the early beginning, to the recent NIH mandate that females be included in pre-clinical as well as clinical research and that research results be reported by sex, the quick read will broaden your understanding of the history of the field and highlight where the future is headed. Illustrates how major universities and organizations around the world concentrated first on the unexplored world of women's biology and then progressively adopted the larger view of the importance of investigating and comparing both sexes through all levels of biomedical research Notes the recent NIH statement that funding would depend on inclusion of two sexes in scientific protocols wherever possible as an important affirmation of the legitimacy of gender specific science Addresses challenges for the future: how to incorporate both sexes in investigative protocols in a scientifically valid way, and whether or not the cost of including two sexes in protocols will be prohibitively expensive Dispels the idea that gender-specific medicine is women's medicine and how changing the name of most of the organizations currently advocating and developing gender specific medicine to include men and women (rather than just women) in their group name would help dispel this notion

The Oxford Handbook of Evolution, Biology, and Society
Author : Rosemary Hopcroft,Rosemary L. Hopcroft
Publisher : Oxford University Press
Release Date : 2018
ISBN 10 : 0190299320
Pages : 688 pages
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Evolution, biology, and society is a catch-all phrase encompassing any scholarly work that utilizes evolutionary theory and/or biological or behavioral genetic methods in the study of the human social group, and The Oxford Handbook of Evolution, Biology, and Society contains an much needed overview of research in the area by sociologists and other social scientists. The examined topics cover a wide variety of issues, including the origins of social solidarity; religious beliefs; sex differences; gender inequality; determinants of human happiness; the nature of social stratification and inequality and its effects; identity, status, and other group processes; race, ethnicity, and race discrimination; fertility and family processes; crime and deviance; and cultural and social change. The scholars whose work is presented in this volume come from a variety of disciplines in addition to sociology, including psychology, political science, and criminology. Yet, as the essays in this volume demonstrate, the potential of theory and methods from biology for illuminating social phenomena is clear, and sociologists stand to gain from learning more about them and using them in their own work. The theory focuses on evolution by natural selection, the primary paradigm of the biological sciences, while the methods include the statistical analyses sociologists are familiar with, as well as other methods that they may not be familiar with, such as behavioral genetic methods, methods for including genetic factors in statistical analyses, gene-wide association studies, candidate gene studies, and methods for testing levels of hormones and other biochemicals in blood and saliva and including these factors in analyses. This work will be of interest to any sociologist with an interest in exploring the interaction of biological and sociological processes. As an introduction to the field it is useful for teaching upper-level or graduate students in sociology or a related social science.

The Strategy of the Genes
Author : C.H. Waddington
Publisher : Routledge
Release Date : 2014-04-29
ISBN 10 : 1317657543
Pages : 274 pages
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First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology: the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate ‘things’ in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.

Sex Differences in the Central Nervous System
Author : Rebecca M. Shansky
Publisher : Academic Press
Release Date : 2015-09-14
ISBN 10 : 0128021985
Pages : 428 pages
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Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population. The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included. Details how sex hormones have widespread effects on the nervous system and influence the way males and females function Assists readers in determining how sex impacts their research and practice, and assists in determining how to adjust research programs to incorporate sex influences Includes discussions of research in both animal models and human patient populations, and at various developmental stages Features revised and updated chapters by leaders in the field around the globe—the broadest, most expert coverage available

Sex Control in Aquaculture
Author : Hanping Wang,Francesc Piferrer,Songlin Chen,Zhi-Gang Shen
Publisher : John Wiley & Sons
Release Date : 2018-11-08
ISBN 10 : 1119127289
Pages : 888 pages
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A comprehensive resource that covers all the aspects of sex control in aquaculture written by internationally-acclaimed scientists Comprehensive in scope, Sex Control in Aquaculture first explains the concepts and rationale for sex control in aquaculture, which serves different purposes. The most important are: to produce monosex stocks to rear only the fastest-growing sex in some species, to prevent precocious or uncontrolled reproduction in other species and to aid in broodstock management. The application of sex ratio manipulation for population control and invasive species management is also included. Next, this book provides detailed and updated information on the underlying genetic, epigenetic, endocrine and environmental mechanisms responsible for the establishment of the sexes, and explains chromosome set manipulation techniques, hybridization and the latest gene knockout approaches. Furthermore, the book offers detailed protocols and key summarizing information on how sex control is practiced worldwide in 35 major aquaculture species or groups, including fish and crustaceans, and puts the focus on its application in the aquaculture industry. With contributions from an international panel of leading scientists, Sex Control in Aquaculture will appeal to a large audience: aquaculture/fisheries professionals and students, scientists or biologists working with basic aspects of fish/shrimp biology, growth and reproductive endocrinology, genetics, molecular biology, evolutionary biology, and R&D managers and administrators. This text explores sex control technologies and monosex production of commercially-farmed fish and crustacean species that are highly in demand for aquaculture, to improve feed utilization efficiency, reduce energy consumption for reproduction and eliminate a series of problems caused by mixed sex rearing. Thus, this book: Contains contributions from an international panel of leading scientists and professionals in the field Provides comprehensive coverage of both established and new technologies to control sex ratios that are becoming more necessary to increase productivity in aquaculture Includes detailed coverage of the most effective sex control techniques used in the world's most important commercially-farmed species Sex Control in Aquaculture is the comprehensive resource for understanding the biological rationale, scientific principles and real-world practices in this exciting and expanding field.