Sex and Gender Differences in Alzheimer's Disease: The Women's Brain Project offers, for the first time, a critical overview of the evidence documenting sex and gender differences in AD neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes and impact on caregivers. This knowledge is crucial for clinical development, digital health solutions, and as social and psychological support to AD families. Presents comprehensive and critical reviews of sex differences in Alzheimer's disease Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists and AI experts for a 360 degree view on the topic and its possible implications Edited by the Women's Brain Project, the leading NGO in the field of sex differences in neuroscience
|Author||: Gorazd Drevensek|
|Publisher||: BoD – Books on Demand|
|Release Date||: 2018-05-02|
|ISBN 10||: 1789230144|
|Pages||: 358 pages|
The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
|Author||: Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences|
|Publisher||: National Academies Press|
|Release Date||: 2001-07-02|
|ISBN 10||: 9780309132978|
|Pages||: 288 pages|
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context
How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges
There is a wide scope of clinical phenomenology in Alzheimers disease, regarding the age of onset, presenting features, rate of progression and appearance of other clinical manifestation. Although clinical appearance and neuropathological hallmarks have been defining AD since its first description, major factors which trigger pathology are still unknown. The role of comorbidity is discussed controversially. Important environmental risk factors in AD development are continuous stress, low education and cardiovascular risk factors such as alcohol intake, smoking, hypertension. The role of lipids and cholesterol has been recognized, but the relevant pathogenetic steps are still to be identified. There is an urgent need to understand molecular disease pathogenesis in order to develop early therapeutic targets for the disease.
This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.
Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population. The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included. Details how sex hormones have widespread effects on the nervous system and influence the way males and females function Assists readers in determining how sex impacts their research and practice, and assists in determining how to adjust research programs to incorporate sex influences Includes discussions of research in both animal models and human patient populations, and at various developmental stages Features revised and updated chapters by leaders in the field around the globe—the broadest, most expert coverage available
Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases
|Author||: National Center for Health Statistics|
|Publisher||: Government Printing Office|
|Release Date||: 2017-08-16|
|ISBN 10||: 9780160939778|
|Pages||: 570 pages|
This annual overview report of national trends in health statistics contains a Chartbook that assesses the nation's health by presenting trends and current information on selected measures of morbidity, mortality, health care utilization and access, health risk factors, prevention, health insurance, and personal health-care expenditures. Chapters devoted to population characteristics, prevention, health risk factors, health care resources, personal health care expenditures, health insurance, and trend tables may provide the health/medical statistician, data analyst, biostatistician with additional information to complete experimental studies or provide necessary research for pharmaceutical companies to gain data for modeling and sampling. Undergraduate students engaged in applied mathematics or statistical compilations to graduate students completing biostatistics degree programs to include statistical inference principles, probability, sampling methods and data analysis as well as specialized medical statistics courses relating to epidemiology and other health topics may be interested in this volume. Related products: Your Guide to Choosing a Nursing Home or Other Long-Term Services & Supports available here: https://bookstore.gpo.gov/products/your-guide-choosing-nursing-home-or-other-long-term-services-supports Health Insurance Coverage in the United States, 2014 available here: https://bookstore.gpo.gov/products/health-insurance-coverage-united-states-2014 "Some System of the Nature Here Proposed": Joseph Lovell's Remarks on the Sick Report, Northern Department, U.S. Army, 1817, and the Rise of the Modern US Army Medical Department can be found here: https://bookstore.gpo.gov/products/some-system-nature-here-proposed-joseph-lovells-remarks-sick-report-northern-department-us Guide to Clinical Preventive Services 2014: Recommendations of the U.S. Preventive Services Task Force (ePub) -Free digital eBook download available at the US Government Online Bookstore here: https://bookstore.gpo.gov/products/guide-clinical-preventive-services-2014-recommendations-us-preventive-services-task-force --Also available for FREE digital eBook download from Apple iBookstore, BarnesandNoble.com (Nook Bookstore), Google Play eBookstore, and Overdrive -Please use ISBN: 9780160926426 to search these commercial platforms.
FINALLY A DIET DESIGNED FOR YOU Based on the latest research showing that men and women metabolize food and lose weight differently, Eat Like a Woman (And Never Diet Again) is a groundbreaking three-step program tailored specifically to the needs of the female body. Staness Jonekos, author of The Menopause Makeover, and leading women's health expert Dr. Marjorie Jenkins show you how to lose weight without deprivation, look younger and feel better than ever. Eat Like a Woman will revolutionize the way you think about food. You'll learn to understand the relationship between stress and your health, interpret the messages your body is sending you, and how to eat to support hormone balance and emotional health. Begin to eat like a woman and in just three weeks you can •Drop those stubborn pounds •Effortlessly maintain a healthy weight •Change your relationship with food •Reduce your risk of disease •Slow the aging process •Exercise smarter Includes favorite recipes from Sheryl Crow, Padma Lakshmi, Florence Henderson, Dolly Parton, Nancy Cartwright, Devin Alexander, Cristina Ferrare, and other popular chefs and celebrities.
A breakthrough work in neuroscience--and an incisive corrective to a long history of damaging pseudoscience--that finally debunks the myth that there is a hardwired distinction between male and female brains We live in a gendered world, where we are ceaselessly bombarded by messages about sex and gender. On a daily basis, we face deeply ingrained beliefs that sex determines our skills and preferences, from toys and colors to career choice and salaries. But what does this constant gendering mean for our thoughts, decisions and behavior? And what does it mean for our brains? Drawing on her work as a professor of cognitive neuroimaging, Gina Rippon unpacks the stereotypes that surround us from our earliest moments and shows how these messages mold our ideas of ourselved and even shape our brains. By exploring new, cutting-edge neuroscience, Rippon urges us to move beyond a binary view of the brain and to see instead this complex organ as highly individualized, profoundly adaptable and full of unbounded potential. Rigorous, timely and liberating, Gender and Our Brains has huge implications for women and men, for parents and children, and for how we identify ourselves.
The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities.
The neurology of sex and bladder disorders requires specialized knowledge and represents a challenge for clinical neurologists focused on the neurological condition. Sex and bladder disorders are often related to more general neurological disorders like Parkinson’s disease and multiple sclerosis, and often the sex and bladder disorders are passed to specialists in urology. Neurology of Sexual and Bladder Disorders: Handbook of Clinical Neurology is a focused, yet comprehensive overview that provides complete tutorial reference to the science, diagnosis and treatment of sex and bladder disorders from a neurologic perspective. Comprehensive coverage of the neurology of sex and bladder disorders Details the latest techniques for the study, diagnosis and treatment of sex and bladder dysfunction from a neurological perspective A focused reference for clinical practitioners and neurology research communities
Biologists have known for decades that many traits involved in competition for mates or other resources and that influence mate choice are exaggerated, and their expression is influenced by the individuals’ ability to tolerate a variety of environmental and social stressors. Evolution of Vulnerability applies this concept of heightened sensitivity to humans for a host of physical, social, psychological, cognitive, and brain traits. By reframing the issue entirely, renowned evolutionary psychologist David C. Geary demonstrates this principle can be used to identify children, adolescents, or populations at risk for poor long-term outcomes and identify specific traits in each sex and at different points in development that are most easily disrupted by exposure to stressors. Evolution of Vulnerability begins by reviewing the expansive literature on traits predicted to show sex-specific sensitivity to environmental and social stressors, and details the implications for better assessing and understanding the consequences of exposure to these stressors. Next, the book reviews sexual selection—mate competition and choice—and the mechanisms involved in the evolution of condition dependent traits and the stressors that can undermine their development and expression, such as poor early nutrition and health, parasites, social stress, and exposure to man-made toxins. Then it reviews condition dependent traits (physical, behavioral, cognitive, and brain) in birds, fish, insects, and mammals to demonstrate the ubiquity of these traits in nature. The focus then turns to humans and covers sex-specific vulnerabilities in children and adults for physical traits, social behavior, psychological wellbeing, and brain and cognitive traits. The sensitivity of these traits is related to exposure to parasites, poor nutrition, social maltreatment, environmental toxins, chemotherapy, and Alzheimer’s disease, among others. The book concludes with an implications chapter that outlines how to better assess vulnerabilities in children and adults and how to more fully understand how, why, and when in development some types of environmental and social stressors are particularly harmful to humans. Describes evolved sex differences, providing predictions on the traits that will show sex-specific vulnerabilities Presents an extensive review of condition-dependent traits in non-human species, greatly expanding existing reviews published in scientific journals, and more critically, extending these to humans Applies condition-dependent traits to humans to identify children, adolescents, or populations at risk for poor long-term outcomes
In the third edition of her popular text, Sex Differences in Cognitive Abilities, Diane Halpern tackles fundamental questions about the meaning of sex differences in cognition and why people are so afraid of the differences. She provides a comprehensive context for understanding the theories and research on this controversial topic. The author employs the psychobiosocial model of cognition to negotiate a cease fire on the nature-nurture wars and offers a more holistic and integrative conceptualization of the forces that make people unique. This new edition reflects the explosion of theories and research in the area over the past several years. New techniques for peering into the human brain have changed the nature of the questions being asked and the kinds of answers that can be expected. There have been surprising new findings on the influence of sex hormones on cognitive abilities across the life span, as well as an increasing number of studies examining how attention paid to category variables such as one's sex, race, or age affects unconscious and automatic cognitive processes. Written in a clear, engaging style, this new edition takes a refreshing look at the science and politics of cognitive sex differences. Although it is a comprehensive and up-to-date synthesis of scientific theory and research into how, why, when, and to what extent females and males differ in intellectual abilities, it conveys complex ideas and interrelationships among variables in an engrossing and understandable manner, bridging the gap between sensationalized 'pop' literature and highly technical scientific journals. Halpern's thought-provoking perspectives on this controversial topic will be of interest to students and professionals alike. [features used for book mailer] FEATURES: *Includes new information about sex differences and similarities in the brain, the role of sex hormones on cognition (including exciting new work on hormone replacement therapy during menopause), new perspectives from evolutionary psychology, the way stereotypes and other group-based expectations unconsciously and automatically influence thought, the influence of pervasive sex-differentiated child rearing and other sex role effects, and understanding how research is conducted and interpreted. *Takes a cognitive process approach that examines similarities and differences in visuospatial working memory, verbal working memory, long-term acquisition and retrieval, sensation and perception, and other stages in information processing. *Provides a developmental analysis of sex differences and similarities in cognition extending from the early prenatal phase into very old age. *Tackles both political and scientific issues and explains how they influence each other--readers are warned that science is not value-free. *Uses cross-cultural data and warns readers about the limitations on conclusions that have not been assessed in multiple cultures. *Includes many new figures and tables that summarize complex issues and provide section reviews. It is a beautifully written book by a master teacher who really cares about presenting a clear and honest picture of contemporary psychology's most politicized topic.
Within the basic and clinical biomedical research community, there is increasing recognition that differences between males and females across the lifespan affect an individual's health, his/her development of disease, signs and symptoms of pathophysiology, and response to therapy. This book is intended as a resource for scientists, clinicians, and students of the nervous system and behavior- a trove of practical information about how to study sex differences in the brain as well as a discussion of what is already known on the topic.
|Author||: Richard C. Friedman,Jennifer I. Downey|
|Publisher||: Columbia University Press|
|Release Date||: 2008-03-24|
|ISBN 10||: 0231504896|
|Pages||: 363 pages|
This book bridges psychoanalytic thought and sexual science. It brings sexuality back to the center of psychoanalysis and shows how important it is for students of human sexuality to understand motives that are often irrational and unconscious. The authors present a new perspective about male and female development, emphasizing the ways in which sexual orientation and homophobia appear early in life. The clinical section of the book focuses on the psychodynamics and treatment of homophobia and internalized homophobia.
|Author||: John L. Oliffe,Lorraine Greaves|
|Release Date||: 2011-04-18|
|ISBN 10||: 1452236550|
|Pages||: 280 pages|
This book provides the first resource dedicated to critically examining gender and sex in study designs, methods, and analysis in health research. In order to produce ethical, accurate, and effective research findings it is vital to integrate both sex (biological characteristics) and gender (socially constructed factors) into any health study. This book draws attention to some of the methodological complexities in this enterprise and offers ways to thoughtfully address these by drawing on empirical examples across a range of topics and disciplines.