salivary biomarkers for oral and systemic diseases

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Salivary Acute Phase Proteins as Biomarker in Oral and Systemic Disease
Author : Assya Krasteva
Publisher : N.A
Release Date : 2011
ISBN 10 :
Pages : 329 pages
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Salivary Acute Phase Proteins as Biomarker in Oral and Systemic Disease.

Salivary Glands
Author : Işıl Adadan Güvenç
Publisher : BoD – Books on Demand
Release Date : 2019-01-30
ISBN 10 : 1789849888
Pages : 136 pages
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Saliva is a complex fluid that maintains oral health and has many physiological functions. It is a noninvasive diagnostic fluid as well. Lately, salivary diagnostics has proven its potential to reach clinical practice in the near future for the early detection, diagnosis, and monitoring of various diseases. Salivary Glands - New Approaches in Diagnostics and Treatment is a comprehensive reference, which brings together information on salivary secretion and its disorders, the novel salivary diagnostic methods for numerous diseases, and new techniques in the treatment of salivary diseases. This book contains information for a diverse audience, including dentists, oral biologists, experimental biologists, molecular biologists, oncologists, radiologists, oral and maxillofacial surgeons, and otorhinolaryngologists.

Advances in Salivary Diagnostics
Author : Charles F. Streckfus
Publisher : Springer
Release Date : 2015-02-03
ISBN 10 : 3662453991
Pages : 204 pages
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This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of “salivaomics” is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.

Salivary Diagnostics
Author : David T. Wong
Publisher : John Wiley & Sons
Release Date : 2009-03-16
ISBN 10 : 081380664X
Pages : 320 pages
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Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.

Saliva in Health and Disease
Author : Asta Tvarijonaviciute
Publisher : Springer Nature
Release Date :
ISBN 10 : 3030376818
Pages : 329 pages
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Use of Saliva in Diagnosis of Periodontitis: Cumulative Use of Bacterial and Host-Derived Biomarkers
Author : Ulvi Kahraman Gürsoy,Eija Könönen
Publisher : Frontiers Media SA
Release Date : 2017-03-15
ISBN 10 : 2889451240
Pages : 329 pages
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Periodontitis is an infection-induced inflammatory disease of the tooth supporting tissues. Treatment of periodontal diseases and regeneration of the effected tissues can be possible only in the early diagnosis of the disease. If left undiagnosed or untreated, periodontitis leads to irreversible soft and hard tissue destruction and finally to tooth loss. Saliva is known to contain inflammatory mediators, host tissue and cell degradation products as well as microbial metabolites and enzymes, reflecting the health status of the oral cavity. In this topic, in collaboration with the well-known scientists working on the field of salivary diagnostics, we demonstrate evidence on monitoring periodontitis by salivary analysis.

Emerging Trends in Oral Health Sciences and Dentistry
Author : Mandeep Virdi
Publisher : BoD – Books on Demand
Release Date : 2015-03-11
ISBN 10 : 9535120247
Pages : 854 pages
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Emerging Trends in Oral Health Sciences and Dentistry is the second book on Oral Health Science. The first book is Oral Health Care-Pediatric, Research, Epidemology and clinical Practices and Oral Health Care-Prosthodontics, Periodontology, Biology, Research and systemic Conditions published in February 2012. The present book is a reflection of the progress in Oral Health Sciences, practices and dentistry indicating the direction in which this stream of knowledge and education is likely to head forward. The book covers areas of General Dentistry, Paediatric and Preventive Dentistry, Geriatric and Prosthodontics, Orthodontics, Periodontology, Conservative Dentistry and Radiology and Oral Medicine.

Studies on Periodontal Disease
Author : Daisuke Ekuni,Maurizio Battino,Takaaki Tomofuji,Edward E. Putnins
Publisher : Springer Science & Business Media
Release Date : 2014-01-09
ISBN 10 : 1461495571
Pages : 370 pages
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The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease. This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.

Saliva as a Diagnostic Fluid
Author : Daniel Malamud,Lawrence A. Tabak
Publisher : N.A
Release Date : 1993
ISBN 10 :
Pages : 348 pages
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Reports on recent advances in detecting drugs, hormones, antibodies, and other molecules of diagnostic importance; research has been going on in such fields as dentistry, clinical chemistry, and steroid hormones, but the researchers have not been talking to each across the disciplinary back fence. A

Acute Phase Proteins as Early Non-Specific Biomarkers of Human and Veterinary Diseases
Author : Francisco Veas
Publisher : BoD – Books on Demand
Release Date : 2011-10-10
ISBN 10 : 9533078731
Pages : 422 pages
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The two volumes of Acute Phase Proteins book consist of chapters that give a large panel of fundamental and applied knowledge on one of the major elements of the inflammatory process during the acute phase response, i.e., the acute phase proteins expression and functions that regulate homeostasis. We have organized this book in two volumes - the first volume, mainly containing chapters on structure, biology and functions of APP, the second volume discussing different uses of APP as diagnostic tools in human and veterinary medicine.

Orofacial Pain Biomarkers
Author : Jean-Paul Goulet,Ana Miriam Velly
Publisher : Springer
Release Date : 2017-03-23
ISBN 10 : 3662539942
Pages : 155 pages
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This book provides up-to-date information on all aspects of orofacial pain biomarkers. It opens by presenting background information on clinical phenotypes and the neurobiological substrates underlying chronic orofacial pain and by explaining the potential role of biomarkers in the diagnosis, prognostic evaluation, and treatment of orofacial pain. The main section of the book examines the contribution of human and animal studies to the field of biomarkers for orofacial pain and discusses biomarkers for masticatory muscle pain, temporomandibular joint pain, neuropathic face pain, and autonomic nervous system involvement in trigeminal facial pain. The potential impacts of the immune system on orofacial pain biomarkers and candidate gene phenotypes with possible links to chronic orofacial pain conditions are also addressed, and differences and similarities between saliva and serum biomarkers for pain are explained as well. The final section covers research-related issues in assessment methods and statistical analyses used in evaluating biomarkers, identifies future challenges and suggests new directions in the field.

Translational Systems Medicine and Oral Disease
Author : Stephen Sonis,Alessandro Villa
Publisher : Academic Press
Release Date : 2019-09-14
ISBN 10 : 0128137630
Pages : 458 pages
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Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Oral Cancer Detection
Author : Prashanth Panta
Publisher : Springer
Release Date : 2019-01-04
ISBN 10 : 3319612557
Pages : 314 pages
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This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Biomarkers in Periodontal Health and Disease
Author : Nurcan Buduneli
Publisher : Springer Nature
Release Date : 2019-12-31
ISBN 10 : 3030373177
Pages : 90 pages
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This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarkers in periodontal diagnosis is then presented in the light of the published data. The biological samples in which potential biomarkers are sought are evaluated comparatively, drawing attention to their strengths and weaknesses, and the available technologies for biomarker studies are reviewed. The potential benefits of biomarkers are also discussed with regard to the possible bidirectional interactions between periodontal diseases and systemic health. Finally, the past, present, and future of periodontics are examined from a broader perspective. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.

Cancer Biomarkers in Body Fluids
Author : Gabriel D. Dakubo
Publisher : Springer Nature
Release Date : 2019-08-29
ISBN 10 : 3030247252
Pages : 296 pages
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The ability to measure and monitor cancer biomarkers in “body fluid biopsy” should greatly impact oncologic practice. “Biomarkers in Proximal Fluids”, the third of the “Cancer Biomarkers in Body Fluids” series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer. Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.

Oral Signs of Systemic Disease
Author : Nasim Fazel
Publisher : Springer
Release Date : 2019-03-26
ISBN 10 : 3030108635
Pages : 266 pages
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This book provides a comprehensive overview of oral signs of a broad spectrum of systemic diseases including gastrointestinal, hematologic, and endocrine, in addition to infectious, nutritional, autoimmune, genetic and connective tissue diseases. An overview of associated key signs and salient features to look for on oral exam is provided as well as other clinical manifestations, differential diagnoses, and treatment recommendations. The mouth is an important anatomical location with a role in many critical physiologic processes that are frequently involved in conditions that affect the skin or other organ systems. In many instances, oral manifestations of a disease precede the appearance of other stigmata. Therefore, early recognition of oral signs and symptoms associated with underlying systemic diseases can be invaluable to the clinician in establishing a diagnosis and prompt initiation of therapy. This book, written for dermatologists, dentists, otolaryngologists, and oral medicine specialists, offers a structured approach to the therapy and management of diseases affecting the oral mucosa.

Orofacial Pain
Author : Reny de Leeuw,American Academy of Orofacial Pain
Publisher : Quintessence Publishing Company
Release Date : 2008
ISBN 10 :
Pages : 316 pages
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Completely revised and updated, this new version of the AAOP Guidelines educates readers on the procedures of evidence-based assessment, diagnosis, and management of orofacial pain conditions based on the latest scientific knowledge. While the structure of the previous version has been maintained, this book offers evidence-based concepts where available and reflects many significant changes in the field of orofacial pain. For example, an entire chapter is now devoted to cervical disorders to emphasize the close relationships between some orofacial pain disorders and cervical pain disorders and to cast greater attention on their differences and similarities. Because they constitute a major part of orofacial pain and affect so many, temporomandibular disorders are the primary topic of several chapters as well as a major focus of the chapter of classification. Other important topics covered in detail include neuropathic pain conditions, odontogenic pain, and mucogingival disorders. This long-awaited edition arms clinicians with new insights and procedures for assessing, diagnosing, and managing patients who present with symptoms of orofacial pain.

Emerging Trends in Oral Health Sciences and Dentistry
Author : Mandeep Virdi
Publisher : BoD – Books on Demand
Release Date : 2015-03-11
ISBN 10 : 9535120247
Pages : 854 pages
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Emerging Trends in Oral Health Sciences and Dentistry is the second book on Oral Health Science. The first book is Oral Health Care-Pediatric, Research, Epidemology and clinical Practices and Oral Health Care-Prosthodontics, Periodontology, Biology, Research and systemic Conditions published in February 2012. The present book is a reflection of the progress in Oral Health Sciences, practices and dentistry indicating the direction in which this stream of knowledge and education is likely to head forward. The book covers areas of General Dentistry, Paediatric and Preventive Dentistry, Geriatric and Prosthodontics, Orthodontics, Periodontology, Conservative Dentistry and Radiology and Oral Medicine.

Saliva: Secretion and Functions
Author : A.J.M. Ligtenberg,E.C.I. Veerman
Publisher : Karger Medical and Scientific Publishers
Release Date : 2014-05-31
ISBN 10 : 3318025968
Pages : 166 pages
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Health professionals are more and more aware of the importance of saliva for oral health and well-being. As saliva secretion is steadily compromised with advancing age, it becomes a factor of concern in societies with an aging population, especially with a growing number of people who keep their own teeth. The numerous functions of saliva, like antimicrobial activity, lubrication, wound healing and its role in taste experience are only truly recognized when saliva secretion is hampered. In medical diagnostics, saliva shows its value as a safe and economical alternative to blood. This publication provides a comprehensive overview of the latest developments in salivary research by some of the world’s leading experts in the field. Chapters deal with various aspects: anatomy and physiology, e.g. regeneration of salivary glands, saliva functions, e.g. its protective and rheological properties, and diagnostics and disorders, e.g. xerostomia and hypersalivation. This book is not only recommended to basic scientists working in the field of oral biology, but also to dental students, dentists and health professionals who want to know more about one of the most underestimated bodily fluids.

Biomarkers in Toxicology
Author : Ramesh C. Gupta
Publisher : Academic Press
Release Date : 2019-02-13
ISBN 10 : 0128146567
Pages : 1246 pages
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Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more