primary immunodeficiency disorders

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Primary Immunodeficiency Disorders
Author : Amos Etzioni,Hans D. Ochs
Publisher : Academic Press
Release Date : 2014-09-13
ISBN 10 : 0124115543
Pages : 376 pages

Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way. Facilitates communication among physicians and other investigators concerned with immunological and inflammatory diseases Summarizes for the first time all the known facts from 60 years of primary immunodeficiency research, and teaches how an important field in medicine was established Provides stimulating discussions on developing new medical therapies Highlights the importance of studying humans to understand mechanisms of disease that affect humans

Primary Immunodeficiency Diseases
Author : Nima Rezaei,Asghar Aghamohammadi,Luigi D. Notarangelo
Publisher : Springer
Release Date : 2016-11-30
ISBN 10 : 3662529092
Pages : 582 pages

The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Primary Immunodeficiency Diseases
Author : Hans D. Ochs,C. I. Edvard Smith,Jennifer Puck
Publisher : Oxford University Press, USA
Release Date : 2007
ISBN 10 : 019514774X
Pages : 726 pages

The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

Clinical Cases in Primary Immunodeficiency Diseases
Author : Asghar Aghamohammadi,Nima Rezaei
Publisher : Springer Science & Business Media
Release Date : 2012-12-13
ISBN 10 : 3642317855
Pages : 380 pages

Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the invaluable cooperation of more than 40 scientists in the field of immunodeficiency. They focus both on the presenting features of patients with PIDs and on the required further investigation and management. Each of the numbered cases is followed by the questions, their answers, and additional discussion. Each question focuses on a particular aspect of the PID under consideration, and the topics covered include clinical diagnosis, laboratory findings, molecular mechanisms, and therapy.

Pulmonary Manifestations of Primary Immunodeficiency Diseases
Author : Seyed Alireza Mahdaviani,Nima Rezaei
Publisher : Springer
Release Date : 2019-02-04
ISBN 10 : 9783030008796
Pages : 286 pages

This book provides a broad overview of the respiratory manifestations associated with Primary Immune deficiencies (PID) congenital genetic defects such as infections, chronic inflammation, autoimmunity, lymphoproliferation, allergic manifestations and rare forms of cancer. Since the most common site of involvement in PID is the lung, the pulmonologists (pediatrics or adult), Internists and General Practitioners may be among the first to recognize the pattern of pulmonary disorders, leading to diagnosis of PID. Pulmonary complications present a significant cause of morbidity and also mortality among patients suffering from different forms of PID. With the prevalence of lung infections and disease so high in PID patients, respiratory professionals will find this book to be an essential resource for diagnosing, managing and referring PID related pulmonary disorders in clinical practice.

Primary Immunodeficiencies Worldwide
Author : Menno C. van Zelm,Antonio Condino-Neto,Mohamed-Ridha Barbouche
Publisher : Frontiers Media SA
Release Date : 2020-02-19
ISBN 10 : 2889635201
Pages : 329 pages

Primary Immunodeficiency Diseases
Author : Hans D. Ochs, MD,,C. I. Edvard Smith, PhD,Jennifer M. Puck, MD
Publisher : Oxford University Press
Release Date : 2013-11-01
ISBN 10 : 019997103X
Pages : 800 pages

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options -- from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy -- this volume will remain an authoritative resource on this increasingly important area.

Primary Immunodeficiency Disorders
Author : Lisa Kobrynski
Publisher : Elsevier Health Sciences
Release Date : 2018-11-22
ISBN 10 : 0323654428
Pages : 329 pages

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.

Stiehm's Immune Deficiencies
Author : Kathleen E Sullivan,E. Richard Stiehm
Publisher : Academic Press
Release Date : 2014-08-08
ISBN 10 : 0124058604
Pages : 1156 pages

Stiehm's Immune Deficiencies focuses on immunodeficiencies in children and adults. This book covers the many advances in the study of immunodeficiency. Stiehm's Immune Deficiencies includes 62 chapters covering topics such as newly described syndromes, genetic diagnosis, molecular abnormalities, newborn screening, and current therapies. Provides practical guidance to practitioners dealing with the day-to-day issues of diagnosis and management of immune deficient patients Covers both clinical management and scientific advances in one place Includes newly described disorders in various periodic updates to maintain the breadth of the reference

The EBMT Handbook
Author : Enric Carreras,Carlo Dufour,Mohamad Mohty,Nicolaus Kröger
Publisher : Springer
Release Date : 2018-12-12
ISBN 10 : 3030022781
Pages : 702 pages

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.

Screening for Primary Immunodeficiency Disorders (PIDDs) in Neonates
Author : Elham Hossny,Antonio Condino-Neto,Lennart Hammarström,Jolan Eszter Walter
Publisher : Frontiers Media SA
Release Date : 2021-02-04
ISBN 10 : 2889664546
Pages : 329 pages

Topic Editor Prof. Lennart Hammarström holds equity in ImmunoIVD. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Primary Immunodeficiency Disorders, An Issue of Immunology and Allergy Clinics of North America 35-4,
Author : Anthony Montanaro
Publisher : Elsevier Health Sciences
Release Date : 2016-01-07
ISBN 10 : 0323413358
Pages : 778 pages

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Anthony Montanaro, MD, is devoted to Primary Immunodeficiency Disorders. Dr. Montanaro has assembled a group of expert authors to review the following topics: Overview of Immunodeficiency Disorder; Severe Combined Immunodeficiency Disorder; Specific Antibody Deficiencies; Common Variable Immunodeficiency; Pulmonary Manifestations of Primary Immunodeficiency Disorders; Approach to the Child with Recurrent Infections; Immunoglobulin Treatment for Primary Immunodeficiency; Bone Marrow Transplantation for Primary Immunodeficiency; and Autoimmune Manifestations of Primary Immunodeficiency.