porous silicon for biomedical applications

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Porous Silicon for Biomedical Applications
Author : Hélder A. Santos
Publisher : Elsevier
Release Date : 2014-02-14
ISBN 10 : 0857097156
Pages : 558 pages
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Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous Silicon for Biomedical Applications provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial. Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing, and explores the optical properties of porous silicon materials; in vivo imaging assessment and radiolabelling of porous silicon; and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumor targeting and imaging, and porous silicon scaffolds for functional tissue engineering, stem cell growth, and osteodifferentiation. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in the field. Comprehensive review of porous silicon focusing on the fabrication and properties of this emerging material Specifically discusses drug delivery and orthopedic applications of porous silicon Aimed at materials researchers and scientists in the biomaterials industry – particularly those concerned with drug delivery and orthopedics

Porous Silicon: From Formation to Application: Biomedical and Sensor Applications, Volume Two
Author : Ghenadii Korotcenkov
Publisher : CRC Press
Release Date : 2016-01-05
ISBN 10 : 1482264579
Pages : 410 pages
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Porous silicon is rapidly attracting increasing interest from various fields, including optoelectronics, microelectronics, photonics, medicine, chemistry, and biosensing. This nanostructured and biodegradable material has a range of unique properties that make it ideal for many applications. For example, the pores and surface chemistry of the material can be manipulated to change the rate of drug release from hours to months. Porous Silicon: Biomedical and Sensor Applications, Volume Two is part of the three-book series Porous Silicon: From Formation to Application. It discusses applications of porous silicon in bioengineering and in various sensors, including gas sensors, biosensors, pressure sensors, mechanical sensors, optical sensors, and many other types. It also thoroughly reviews the fabrication, parameters, and applications of devices that use porous silicon. Drawing upon a vast amount of recently published literature, the book guides readers through practical implementations that span environmental control, chemistry, spectroscopy, gas chromatography, microelectronics, micromachining, microfluidics, medicine, biotechnology, and the car industry. It is divided into three sections that focus on: Types of sensors that use porous silicon Auxiliary devices that use porous silicon Biomedical applications such as drug delivery, tissue engineering, and in vivo imaging Representing the most recent progress in applications of porous silicon to biomedical and sensory technology, this reference is indispensable for those involved in the research, development, and application of porous silicon in several scientific disciplines. It also serves as a starting point for the interested but unfamiliar reader to gain a thorough understanding of the unusual properties of porous silicon, other porous materials, and possible areas for current and future applications.

Porous Silicon
Author : Ghenadii Korotcentkov
Publisher : CRC Press
Release Date : 2016-01-04
ISBN 10 : 9781482264562
Pages : 440 pages
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Porous silicon is rapidly attracting increasing interest from various fields, including optoelectronics, microelectronics, photonics, medicine, chemistry, and biosensing. This nanostructured and biodegradable material has a range of unique properties that make it ideal for many applications. For example, the pores and surface chemistry of the material can be manipulated to change the rate of drug release from hours to months. Porous Silicon: Biomedical and Sensor Applications, Volume Two is part of the three-book series Porous Silicon: From Formation to Application. It discusses applications of porous silicon in bioengineering and in various sensors, including gas sensors, biosensors, pressure sensors, mechanical sensors, optical sensors, and many other types. It also thoroughly reviews the fabrication, parameters, and applications of devices that use porous silicon. Drawing upon a vast amount of recently published literature, the book guides readers through practical implementations that span environmental control, chemistry, spectroscopy, gas chromatography, microelectronics, micromachining, microfluidics, medicine, biotechnology, and the car industry. It is divided into three sections that focus on: Types of sensors that use porous silicon Auxiliary devices that use porous silicon Biomedical applications such as drug delivery, tissue engineering, and in vivoimaging Representing the most recent progress in applications of porous silicon to biomedical and sensory technology, this reference is indispensable for those involved in the research, development, and application of porous silicon in several scientific disciplines. It also serves as a starting point for the interested but unfamiliar reader to gain a thorough understanding of the unusual properties of porous silicon, other porous materials, and possible areas for current and future applications.

Porous Silicon: From Formation to Application: Formation and Properties, Volume One
Author : Ghenadii Korotcenkov
Publisher : CRC Press
Release Date : 2016-04-21
ISBN 10 : 1482264552
Pages : 423 pages
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Porous silicon is rapidly attracting increasing interest in various fields, including optoelectronics, microelectronics, photonics, medicine, chemistry, biosensing, and energy. Porous Silicon: Formation and Properties fills a gap in the literature of the field today, providing a thorough introduction to current knowledge of the formation, processing, and properties of porous silicon. It also analyzes present and potential applications of porous silicon in technology, including various devices. With contributions from an international team of well-known experts, this book presents the most recent progress in the field of porous silicon. Focused chapters cover the fundamentals of silicon porosification, the qualities of porous silicon, including its electrical, luminescent, optical, and thermal properties, and the processing of porous silicon for use in the technology of other fields. It also gives valuable insights on what can be expected from the field in the near future. The book includes extensive references to recently published literature on the subject, allowing for deeper exploration of information on the porosification process, designing porous silicon-based technology, and improving performance of devices fabricated using porous silicon. It is an indispensable addition to the library of any scientist or technician involved or interested in the research, development, and application of porous silicon.

Handbook of Porous Silicon
Author : Leigh Canham
Publisher : Springer
Release Date : 2021-01-14
ISBN 10 : 9783319045085
Pages : 1000 pages
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The Handbook of Porous Silicon brings together the expertise of a large, international team of almost 100 academic researchers, engineers, and product developers from industry across electronics, medicine, nutrition and consumer care to summarize the field in its entirity with 150 chapters and 5000 references. The volume presents 5 parts which cover fabrication techniques, material properties, characterization techniques, processing and applications. Much attention was given in the the past to its luminescent properties, but increasingly it is the biodegradability, mechanical, thermal and sensing capabilities that are attracting attention. The volume is divided into focussed data reviews with, wherever possible, quantitative rather than qualitative descriptions of both properties and performance. The book is targeted at undergraduates, postgraduates, and experienced researchers.

Porous Silicon: Biomedical and sensor applications
Author : Gennadiĭ Sergeevich Korotchenkov
Publisher : CRC Press, Taylor & Francis Group, CRC Press is
Release Date : 2016
ISBN 10 :
Pages : 329 pages
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Electrochemically Engineered Nanoporous Materials
Author : Dusan Losic,Abel Santos
Publisher : Springer
Release Date : 2015-07-18
ISBN 10 : 3319203460
Pages : 364 pages
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This book provides in-depth knowledge about the fabrications, structures, properties and applications of three outstanding electrochemically engineered nanoporous materials including porous silicon, nanoporous alumina and nanotubular titania. The book integrates three major themes describing these materials. The first theme is on porous silicon reviewing the methods for preparation by electrochemical etching, properties and methods for surface functionalization relevant for biosensing applications. Biomedical applications of porous silicon are major focus, described in several chapters reviewing recent developments on bioanalysis, emerging capture probes and drug delivery. The second theme on nanoporous alumina starts with describing the concept of self-organized electrochemical process used for synthesis nanopore and nanotube structures of valve metal oxides and reviewing recent development and progress on this field. The following chapters are focused mainly on optical properties and biosensing application of nanoporous alumina providing the reader with the depth of understanding of the structure controlled optical and photonic properties and design of optical biosensing devices using different detection principles such as photoluminescence, surface plasmon resonance, reflective spectrometry, wave guiding, Raman scattering etc. The third theme is focused on nanotubular titania reviewing three key applications including photocatalysis, solar cells and drug delivery. The book represents an important resource for academics, researchers, industry professionals, post-graduate and high-level undergraduate students providing them with both an overview of the current state-of-the-art on these materials and their future developments.

Inorganic Frameworks as Smart Nanomedicines
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release Date : 2018-04-09
ISBN 10 : 0128136626
Pages : 726 pages
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Inorganic Frameworks as Smart Nanocarriers for Drug Delivery brings together recent research in the area of inorganic frameworks for drug delivery. Different types of nanocarriers are presented and discussed in detail, providing an up-to-date overview on inorganic nanoparticles with pharmaceutical applications. Written by a diverse range of international academics, this book is a valuable reference resource for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of inorganic smart nanocarriers. Includes assembly methods for a variety of smart nanocarrier systems, also showing how they are applied Highlights how metal-oxide nanoparticles are effectively used in drug delivery Assesses the pros and cons of different metallic nanomaterials as drug carriers

Hydroxyapatite (HAp) for Biomedical Applications
Author : Michael Mucalo
Publisher : Elsevier
Release Date : 2015-03-06
ISBN 10 : 178242041X
Pages : 404 pages
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Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. Reviews the important properties of hydroxyapatite as a biomaterial Considers a range of specific forms of the material and their advantages Reviews a range of specific medical applications for this important material

Nanosilicon
Author : Vijay Kumar
Publisher : Elsevier
Release Date : 2011-07-28
ISBN 10 : 9780080549514
Pages : 388 pages
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Properties of nanosilicon in the form of nanoparticles, nanowires, nanotubes, and as porous material are of great interest. They can be used in finding suitable components for future miniature devices, and for the more exciting possibilities of novel optoelectronic applications due to bright luminescence from porous silicon, nanoparticles and nanowires. New findings from research into metal encapsulated clusters, silicon fullerenes and nanotubes have opened up a new paradigm in nanosilicon research and this could lead to large scale production of nanoparticles with control on size and shape as well as novel quasi one-dimensional structures. There are possibilities of using silicon as an optical material and in the development of a silicon laser. In Nanosilicon, leading experts cover state-of-the-art experimental and theoretical advances in the different forms of nanosilicon. Furthermore, applications of nanosilicon to single electron transistors, as photonic material, chemical and biological sensors at molecular scale, and silicon nanowire devices are also discussed. Self-assemblies of silicon nanoforms are important for applications. These developments are also related to cage structures of silicon in clathrates. With an interesting focus on the bottlenecks in the advancement of silicon based technology, this book provides a much-needed overview of the current state of understanding of nanosilicon research. Latest developments in nanoparticles, nanowires and nanotubes of silicon Focus on nanosilicon - a very timely subject attracting large interest Novel chapters on metal encapsulated silicon clusters and nanotubes

New Research on Silicon
Author : Vitalyi Igorevich Talanin
Publisher : BoD – Books on Demand
Release Date : 2017-05-31
ISBN 10 : 9535131591
Pages : 304 pages
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The knowledge of fundamental silicon questions and all aspects of silicon technology gives the possibility of improvement to both initial silicon material and devices on silicon basis. The articles for this book have been contributed by the much respected researchers in this area and cover the most recent developments and applications of silicon technology and some fundamental questions. This book provides the latest research developments in important aspects of silicon including nanoclusters, solar silicon, porous silicon, some technological processes, and silicon devices and also fundamental question about silicon structural perfection. This book is of interest both to fundamental research and to practicing scientists and also will be useful to all engineers and students in industry and academia.

Porous Silicon Nanomaterials for Bioimaging and Nanomedicine
Author : Jinyoung Kang
Publisher : N.A
Release Date : 2018
ISBN 10 :
Pages : 209 pages
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There is increased interest in porous silicon nanomaterials for biomedical applications due to their biodegradability, their biocompatibility, and their intrinsic photoluminescence. This thesis describes cargo loading chemistry, surface chemistry, molecularly targeted delivery and bioimaging applications using porous silicon nanomaterials. After a brief introduction to porous silicon materials for biomedical applications, Chapter 2 describes a single-step procedure to simultaneously load and protect a model siRNA therapeutic in porous silicon nanoparticles (pSiNPs). Exogenous calcium ions precipitate with locally generated silicic acid to form calcium silicate, which serves to encapsulate the siRNA payload in pSiNPs. The target gene knockdown efficiency in vitro and target tissue accumulation of delivered siRNA in vivo are demonstrated. Chapter 3 presents a facile chemical modification of the surface of the hydroxylated silicon nanostructure. The reaction, a ring-opening heterocyclic silane "click" reaction, is a rapid and efficient means to obtain high surface coverage while preserving the open pore structure and intrinsic photoluminescence of the original silicon nanostructure. This chemistry is sufficiently mild to maintain the activity of payload proteins. Chapter 4 presents the example of pSiNPs as an imaging agent, which are targeted to tumor tissues in vivo using an iRGD peptide targeting probe, and the nanoparticles are imaged by two-photon microscopy. Superior photostability and low systemic toxicity are observed. Chapter 5 discusses enhanced photoacoustic signals that can be obtained from indocyanine green (ICG) when it is encapsulated in pSiNPs. The photoacoustic response from ICG is enhanced 17-fold when it is sealed in pSiNPs. The substantially improved performance is attributed to the low thermal conductivity of pSiNPs and their ability to protect loaded ICG from photolytic degradation.