Polymeric Supports for Enzyme Immobilization: Opportunities and Applications offers in-depth discussions of known polymeric enzyme support materials, reaction processes and optimized methods to enhance enzyme immobilization. Case-based chapters examine uses across the fields of medicine, environmental science, industrial science, clean energy, and even space exploration. Discussions of immobilized enzymes in drug delivery systems, development of ELISA (enzyme linked immunosorbent assays), antibiotics production, biosensor production, planetary exploration, treatment for lactose intolerance, diabetes and arthritis are prominently featured. Throughout, emphasis is placed on future opportunities and next steps in each area of research application. Offers an in-depth, case-driven discussion of known polymeric enzyme support materials, associated reaction processes, and methods to enhance enzyme immobilization Examines applications across medicine, environmental science, the industrial sciences, clean energy and space exploration Provides optimal strategies for various enzymes, processes and applications, considering the enzyme itself, substrate and available support properties
This monograph contains manuscripts, poster abstracts and summary statements representing the contributions of a group of scientists who participated in the sixth annual Texas A&M Industry-University Cooperative Chemistry Program (IUCCP) at Texas A&M University in College Station, Texas, March 22-24, 1988. This symposium on "Functional Polymers" was organized by a university-industrial steering committee consisting of Dr. D. Keene, Hoechst Celanese; Dr. D. E. McLemore, Dow Chemical Company; Dr. B. Frushour, Monsanto Company; Dr. S. Corley, Shell Development; Dr. F. Hoffstadt, BPAmerica; Dr. D. E. Bergbreiter, Texas A&M University; Dr. C. A. J. Hoeve, Texas A&M University; Dr. C. R. Martin, Texas A&M University; Dr. A. Clearfield, Texas A&M University; and Dr. A. E. Martell, Texas A&M University. The symposium itself was generously supported by the industrial companies participating in the IUCCP program. These sponsoring chemical companies include; Shell Development Company, Dow Chemical Company, BPAmerica, Monsato Company and Hoechst Celanese. The choice of "Functional Polymers" as the subject for this symposium reflects the rapid developments occurring in the broad field of polymer science and the potential for using polymeric derivatives in many new exciting and potentially profitable applications. The invited papers and submitted posters reflect the diversity of this field and include many different topics ranging from biomedical applications of polymers to conducting polymers to use of polymers as lithographic masks and recording media. General topics included in the symposium were: photoresponsive polymers, polymer blends, electronically conductive polymers, polymers catalysts, biomedical polymers and membrane transport and permeability.
|Author||: Rui L. Reis,Nuno M. Neves,Joao F. Mano,Manuela E. Gomes,Alexandra P. Marques,Helena S. Azevedo|
|Release Date||: 2008-08-15|
|ISBN 10||: 1845694813|
|Pages||: 832 pages|
Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering. The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility. Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. Examines the sources, processing and properties of natural based polymers for biomedical applications Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine
|Author||: Rui L. Reis,Julio San Román|
|Publisher||: CRC Press|
|Release Date||: 2004-11-29|
|ISBN 10||: 9780203491232|
|Pages||: 592 pages|
Conventional materials technology has yielded clear improvements in regenerative medicine. Ideally, however, a replacement material should mimic the living tissue mechanically, chemically, biologically and functionally. The use of tissue-engineered products based on novel biodegradable polymeric systems will lead to dramatic improvements in health
This book is a printed edition of the Special Issue "Immobilized Biocatalysts" that was published in Catalysts
The first systematic overview of this key technique since the early 1990s, this authoritative reference is the only handbook available to include all recent developments. The author draws on his wide-ranging experience in both academia and industry to systematically cover all types of enzyme immobilization methods, such as adsorption-based and covalent immobilization, as well as enzyme entrapment and encapsulation. Throughout, a careful review of materials and techniques for the generation of functional immobilized enzymes benefits both developers and users of carrier-bound enzymes. A must for biotechnologists, biochemists and preparative chemists using enzymes in their daily work.
In reversible deactivation radical polymerization, some chemical links are dormant.
This book covers the latest developments in enzyme immobilization with its wide applications, such as for industry, agriculture, medicine, and the environment. Topics covered include basics of enzyme immobilization, its implication in therapeutics and disease diagnostics, and its significance in solving environmental problems. This is an ideal book for researchers, graduate and postgraduate students, as well as scientists in industry, agriculture and health sectors. This book is a complete summary of enzyme immobilization and also thoroughly covers all the latest research. This book covers: The last one-hundred years of innovative research done in enzyme immobilization Recent developments in immobilization techniques, such as types of matrices, immobilization methods, and linking agents, as well as enzyme immobilization without any matrices and its properties The physiological and industrial significance of enzymes from plants and the implementation of immobilized enzymes in the treatment of waste water and polluted air Biomedical and bioanalytical applications of immobilized enzymes
For most of industrial applications, enzymes and cells have to be immobilized, via very simple and cost-effective protocols, in order to be re-used for very long periods of time. From this point of view, immobilization, simplicity and stabilization have to be strongly related concepts. The third edition of Immobilization of Enzymes and Cells expands upon and updates the previous editions with current, detailed protocols for immobilization. With new chapters on protocols for immobilization of enzymes and cells which may be useful to greatly improve the functional properties of enzymes and cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immobilization of Enzymes and Cells, Third Edition demonstrates simple and efficient protocols for the preparation, characterization, and utilization of immobilized enzymes and cells.
This fourth edition volume expands on the previous editions with new insights on important aspects to take into accounting when immobilizing enzymes and cells, illustrating outstanding examples that support those aspects, and exploring ways to fabricate and characterize heterogeneous biocatalysts including both immobilized enzymes and cells. The transformation of soluble and usually instable enzymes into heterogeneous and highly stable biocatalysts is strongly emphasized. The chapters in this book cover topics such as the importance of enzyme orientation on the support surface; application and characterization of immobilized enzymes; different functionalization chemistries for the modulation of the immobilized enzyme properties; co-immobilization of multi-enzyme systems; new analytical techniques for the characterization of heterogeneous biocatalysts; protocols for cell entrapment in alginate; preparation and characterization of biofilms; and cell encapsulation technologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Immobilization of Enzymes and Cells: Methods and Protocols, Fourth Edition is a valuable resource for researchers interested in expanding their knowledge of this developing field.
During the past decade, monolithic materials in the shape of discs, stacked layers, rolled sheets, sponges, irregular chunks, tubes, and cylinders have all been successfully demonstrated. These formats were prepared from a wide variety of materials including natural polymers such as cellulose, synthetic polymers that involved porous styrene-, methacrylate-, and acrylamide-based polymers, and inorganic materials, mainly silica. Each approach is interesting from the point of view of both preparation and application. Although the current papers and patents concerned with monolithic separation media are quite numerous, the information is scattered throughout a vast number of journals. This book therefore fills the gap in the market for a comprehensive reference book on this subject. Monolithic materials concerns all of the current formats of monolithic materials and provides an integrated view of this novel format of separation media. Since the flow pattern in monolithic devices is different from that in packed beds, the hydrodynamics of the system and mass transport differ considerably from those derived for packed columns. Therefore, this book presents contributions concerned with both flow and mass transfer in the monolithic materials. A significant proportion of the book is devoted to the applications of monolithic materials. It also provides the reader with valuable information about the sources of the specific materials, their properties, and potential applications. · Monolithic materials are currently very popular within several scientific areas such as chromatography, optics, catalysis, diagnostics, genomics, proteomics, and microfluidics. · Provides valuable information about the sources of the specific materials, their properties, and potential applications. · Chapters written by leading experts in the area.