No book has been published that gives a detailed description of all the types of plastic materials used in medical devices, the unique requirements that the materials need to comply with and the ways standard plastics can be modified to meet such needs. This book will start with an introduction to medical devices, their classification and some of the regulations (both US and global) that affect their design, production and sale. A couple of chapters will focus on all the requirements that plastics need to meet for medical device applications. The subsequent chapters describe the various types of plastic materials, their properties profiles, the advantages and disadvantages for medical device applications, the techniques by which their properties can be enhanced, and real-world examples of their use. Comparative tables will allow readers to find the right classes of materials suitable for their applications or new product development needs.
|Author||: Ajay Padsalgikar|
|Publisher||: William Andrew|
|Release Date||: 2017-02-01|
|ISBN 10||: 0323371221|
|Pages||: 196 pages|
Plastics in Medical Devices for Cardiovascular Applications enables designers of new cardiovascular medical devices to make decisions about the kind of plastics that can go into the manufacture of their device by explaining the property requirements of various applications in this area, including artificial valves, lead insulation, balloons, vascular grafts, and more. Enables designers to improve device performance and remain compliant with regulations by selecting the best material for each application Presents a range of applications, including artificial valves, stents, and vascular grafts Explains which materials can be used for each application, and why each is appropriate, thus assisting in the design of better tools and processes
|Author||: Sina Ebnesajjad|
|Publisher||: Elsevier Inc. Chapters|
|Release Date||: 2013-12-05|
|ISBN 10||: 0128076682|
|Pages||: 368 pages|
This chapter focuses on adhesives used in direct physiological contact in dental and medical procedures. Activity in both areas has been quite extensive outside the United States for decades. In contrast, adhesive use in medical devices, patches, and plasters has been ongoing in the United States for a long time. In the case of medical devices, adhesion is concerned with the joining of materials such as plastics, elastomers, textiles, metals, and ceramics, which are examined in other chapters of the present volume and are covered in various references [1–6], The coverage of this chapter is devoted to applications where to adhesives are in direct contact with tissues and other live organs.
The use of plastics is widespread. Less widespread, however, is a clear understanding and examination of the many forms of degradation inherent within the very environments these materials must perform. Medical PlasticsùDegradation Resistance & Failure Analysis fills that void. The introductory chapter gives an overview of the medical applications of plastics and the specific performance requirements they need to meet. The following chapters discuss various degrading environments and their effects including environmental stress cracking, effect of body liquids, effect of harsh environments, and various methods of sterilization. The book also discusses the failure of medical devices due to contamination, low temperature, the effects of UV light, migration of formulation components, mechanical stresses, and problems with design and fabrication. Case histories of failures of some common products used in medicine are also provided.
|Author||: Markus Schönberger,Marc Hoffstetter|
|Publisher||: William Andrew|
|Release Date||: 2016-01-06|
|ISBN 10||: 0323374654|
|Pages||: 302 pages|
Emerging Trends in Medical Plastic Engineering and Manufacturing gives engineers and materials scientists working in the field detailed insights into upcoming technologies in medical polymers. While plastic manufacturing combines the possibility of mass production and wide design variability, there are still opportunities within the plastic engineering field which have not been fully adopted in the medical industry. In addition, there are numerous additional challenges related to the development of products for this industry, such as ensuring tolerance to disinfection, biocompatibility, selecting compliant additives for processing, and more. This book enables product designers, polymer processing engineers, and manufacturing engineers to take advantage of the numerous upcoming developments in medical plastics, such as autoregulated volume-correction to achieve zero defect production or the development of ‘intelligent’ single use plastic products, and methods for sterile manufacturing which reduce the need for subsequent sterilization processes. Finally, as medical devices get smaller, the book discusses the challenges posed by miniaturization for injection molders, how to respond to these challenges, and the rapidly advancing prototyping technologies. Provides a roadmap to the emerging technologies for polymers in the medical device industry, including coverage of ‘intelligent’ single use products, personalized medical devices, and the integration of manufacturing steps to improve workflows Helps engineers in the biomedical and medical devices industries to navigate and anticipate the special requirements of this field with relation to biocompatibility, sterilization methods, and government regulations Presents tactics readers can use to take advantage of rapid prototyping technologies, such as 3D printing, to reduce defects in production and develop products that enable entirely new treatment possibilities
|Author||: Y N Zhou,M D Breyen|
|Release Date||: 2013-05-31|
|ISBN 10||: 0857096427|
|Pages||: 574 pages|
As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications. Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications. Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives
|Author||: Laurence W. McKeen|
|Publisher||: William Andrew|
|Release Date||: 2018-02-22|
|ISBN 10||: 0128145129|
|Pages||: 468 pages|
The Effect of Sterilization Methods on Plastics and Elastomers, Fourth Edition brings together a wide range of essential data on the sterilization of plastics and elastomers, thus enabling engineers to make optimal material choices and design decisions. The data tables in this book enable engineers and scientists to select the right materials and sterilization method for a given product or application. The book is a unique and essential reference for anybody working with plastic materials that are likely to be exposed to sterilization methods, be it in medical device or packaging development, food packaging or other applications. Presents essential data and practical guidance for engineers and scientists working with plastics in applications that require sterile packaging and equipment Updated edition removes obsolete data, updates manufacturers, verifies data accuracy, and adds new plastics materials for comparison Provides essential information and guidance for FDA submissions required for new medical devices
UHMWPE Biomaterials Handbook describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated knowledge on these two classes of materials are a key feature of the 2nd edition, along with an additional 19 additional chapters providing coverage of the key engineering aspects (biomechanical and materials science) and clinical/biological performance of UHMWPE, providing a more complete reference for industrial and academic materials specialists, and for surgeons and clinicians who require an understanding of the biomaterials properties of UHMWPE to work successfully on patient applications. The UHMWPE Handbook is the comprehensive reference for professionals, researchers, and clinicians working with biomaterials technologies for joint replacement New to this edition: 19 new chapters keep readers up to date with this fast moving topic, including a new section on UHMWPE biomaterials; highly crosslinked UHMWPE for hip and knee replacement; Vitamin E stabilized UHMWPE for patients; clinical performance, tribology an biologic interaction of UHMWPE State-of-the-art coverage of UHMWPE technology, orthopedic applications, biomaterial characterisation and engineering aspects from recognised leaders in the field
This new text provides a practical guide to hydrophilic polymer coatings technology for applications in a wide range of medical materials and devices. It concisely provides both the scientific basics of this class of polymers and the up-to-date information needed for product development and evaluation, processing, manufacturing, and regulatory compliance. More than fifty schematics illustrate materials, processes, and equipment. The entire presentation is oriented to the practical needs of personnel involved in product development and evaluation, process engineering, and manufacturing management.
The Medical Device R&D Handbook presents a wealth of information for the hands-on design and building of medical devices. Detailed information on such diverse topics as catheter building, prototyping, materials, processes, regulatory issues, and much more are available in this convenient handbook for the first time. The Medical Device R&D Ha
|Author||: Sina Ebnesajjad|
|Publisher||: William Andrew|
|Release Date||: 2012-12-31|
|ISBN 10||: 1455730033|
|Pages||: 472 pages|
Biopolymers and Biodegradable Plastics are a hot issue across the Plastics industry, and for many of the industry sectors that use plastic, from packaging to medical devices and from the construction indusry to the automotive sector. This book brings together a number of key biopolymer and biodegradable plastics topics in one place for a broad audience of engineers and scientists, especially those designing with biopolymers and biodegradable plastics, or evaluating the options for switching from traditional plastics to biopolymers. Topics covered include preparation, fabrication, applications and recycling (including biodegradability and compostability). Applications in key areas such as films, coatings controlled release and tissue engineering are discussed. Dr Ebnesajjad provides readers with an in-depth reference for the plastics industry – material suppliers and processors, bio-polymer producers, bio-polymer processors and fabricators – and for industry sectors utilizing biopolymers – automotive, packaging, construction, wind turbine manufacturers, film manufacturers, adhesive and coating industries, medical device manufacturers, biomedical engineers, and the recycling industry. Essential information and practical guidance for engineers and scientists working with bioplastics, or evaluating a migration to bioplastics. Includes key published material on biopolymers, updated specifically for this Handbook, and new material including coverage of PLA and Tissue Engineering Scaffolds. Coverage of materials and applications together in one handbook enables engineers and scientists to make informed design decisions.
Thermosetting plastics are a distinct category of plastics whose high performance, durability and reliability at high temperatures makes them suitable for specialty applications ranging from automotive and aerospace through to electronic packaging and consumer products (your melamine kitchen worktop is a thermoset resin!). Recent developments in thermoset plastics technology and processes has broadened their use exponentially over recent years, and these developments continue: in November 2011, French scientists created a new lightweight thermoset that is as strong and stable as previous materials yet can be easily reworked and reshaped when heated which makes it unique amongst thermosets and allows for repair and recycling. The Handbook of Thermoset Plastics, now in its 3rd edition, provides a comprehensive survey of the chemical processes, manufacturing techniques and design properties of each polymer, along with their applications. Written by a team of highly experienced practitioners, the practical implications of using thermoset plastics are presented – both their strengths and weaknesses. The data and descriptions presented here enable engineers, scientists and technicians to form judgments and take action on the basis of informed analysis. The aim of the book is to help the reader to make the right decision and take the correct action – avoiding the pitfalls the authors’ experience has uncovered. The new edition has been updated throughout to reflect current practice in manufacturing and processing, featuring: Case Studies to demonstrate how particular properties make different polymers suitable for different applications, as well as covering end-use and safety considerations. A new chapter on using nanoparticles to enhance thermal and mechanical properties. A new chapter describing new materials based on renewable resources (such as soy-based thermoset plastics). A new chapter covering recent developments and potential future technologies such as new catalysts for Controlled Radical Polymerization. Goodman and Dodiuk-Kenig provide a comprehensive reference guide to the chemistry, manufacturing and applications of thermosets. Updated to include recent developments in manufacturing – from biopolymers to nanocomposites. Case Studies illustrate applications of key thermoset plastics.