organofluorine chemistry

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Organofluorine Chemistry
Author : Kenji Uneyama
Publisher : John Wiley & Sons
Release Date : 2008-04-15
ISBN 10 : 1405172932
Pages : 352 pages
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The replacement of hydrogen with fluorine in organic molecules canprofoundly influence their chemical and physical properties,leading to a range of compounds with highly desirable properties.These molecules are of interest across the wide spectrum ofindustrial and academic organic chemistry, so that organofluorinechemistry is economically highly important. Organofluorine Chemistry will help chemists to develop a systematicknowledge of the chemistry of fluorine with a view towards itsapplication in the design of new reactions and syntheses, and thecreation of novel fluorinated molecules and materials. With initialchapters focusing on why fluorine creates such unique properties inorganic compounds, the book then covers general reactions offluorine. Coverage is chosen from the recent research literature,concentrating on the development of novel bioactive compounds andcatalytic ligands, and explaining, in the context of the initialchapters, how and why fluorine is so effective. With a finalchapter covering the general synthetic chemistry of organofluorinecompounds, the book is a cohesive summary of the fundamentalprincipals of organofluorine chemistry.

Organofluorine Chemistry
Author : V. Prakash Reddy
Publisher : Elsevier
Release Date : 2020-03-20
ISBN 10 : 0128132876
Pages : 358 pages
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Organofluorine Chemistry: Synthesis and Applications gives a comprehensive outlook on modern synthetic methodologies for organofluorine compounds. It illustrates chemical, biochemical, and materials applications of fluorine-containing compounds, including synthesis and applications of small molecule compounds in drug discovery, positron emission tomography, and fluorinated polymers in solar cells. This book is of use to scientists working in the interdisciplinary areas, such as chemical, biochemical, and biomedical engineering, as well as those involved in materials science and medicinal chemistry. It is also a useful reference for researchers and graduate students interested in organofluorine chemistry. Provides modern synthetic methods and reactions of organofluorine compounds Incorporates the synthesis and chemical, biochemical and biomedical applications of fluorine-containing compounds, nanomaterials, PET imaging agents, pharmaceuticals, and polymeric materials Features emerging "hot" topics, such as late-stage fluorinations and drug discovery

Organofluorine Chemistry
Author : Richard D. Chambers
Publisher : Springer
Release Date : 2003-09-05
ISBN 10 : 3540691979
Pages : 252 pages
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The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.

Frontiers Of Organofluorine Chemistry
Author : Ojima Iwao
Publisher : World Scientific
Release Date : 2019-12-24
ISBN 10 : 1786347342
Pages : 844 pages
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This book focuses on the new frontiers of organofluorine chemistry in synthetic, organometallic, bioorganic, medicinal, agricultural, and materials chemistry as well as chemical physics and their applications to biomedical and material sciences. The extraordinary potential of fluorine-containing molecules in biology, pharmaceuticals, agrochemical, materials and their wide range of applications has been recognized by researchers who are not in the traditional fluorine chemistry field, and thus the new wave of organofluorine chemistry is rapidly expanding its frontiers.Featuring major leading researchers from all over the world and their cutting-edge research projects, this title reviews the recent advances and envision the new exciting developments in the future. Frontiers of Organofluorine Chemistry is an excellent reference book for professional researchers, and graduate students, in both industry and academia to get inspirations and new ideas for their projects.

Organofluorine Chemistry
Author : R.E. Banks,B.E. Smart,J.C. Tatlow
Publisher : Springer Science & Business Media
Release Date : 2013-11-11
ISBN 10 : 1489912029
Pages : 644 pages
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During the past fifteen years commercial interest in compounds containing carbon fluorine bonds has burgeoned beyond all expectations, mainly owing to business opportunities arising from work on biologically active fluoroorganics-particularly agrochemicals, the relentless search for new markets for fluoropolymers and fluoro carbon fluids, developments in the field of medical diagnostics, and the drive to find replacements for ozone-depleting CFCs and Halon fire-extinguishing agents. Judging the situation to warrant the publication of a comprehensive collection of up-to-date reviews dealing with commercial organofluorine compounds within a single volume of manageable size (and hence reasonable cost), we were delighted to be invited by Plenum Publishing Corporation to produce a suitable book. In order to provide an authentic and wide-ranging account of current commercial applications of fluoroorganic materials, it clearly was necessary to assemble a sizeable team of knowledgeable contributing authors selected almost entirely from industry. Through their efforts we have been able to produce an almost complete coverage of the modem organofluorochemicals business in a manner designed to attract a reader ship ranging from experts in the field, through chemists and technologists currently unaware of the extent of industrial involvement with fluoroorganics, to students of applied chemistry. Promised chapters dedicated to perfluoroolefin oxides and 18F labeling of radiopharmaceuticals failed to materialize. This is somewhat unfortunate in view of our aim to achieve comprehensive coverage of the subject.

Organofluorine Compounds in Biology and Medicine
Author : V Prakash Reddy
Publisher : Newnes
Release Date : 2015-01-25
ISBN 10 : 044453749X
Pages : 330 pages
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This book covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry

Organofluorine Compounds
Author : Tamejiro Hiyama
Publisher : Springer Science & Business Media
Release Date : 2013-03-09
ISBN 10 : 3662041642
Pages : 272 pages
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In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and material sciences. In particular, the book will emphasize on the usefulness of fluorination reaction, availability of fluorination agents, so that even graduate students who are unfamiliar to this field can understand and participate in this fascinating heteroatom chemistry.

Organofluorine Chemistry: Principles and Commercial Applications
Author : B.E. Smart,J.C. Tatlow
Publisher : Springer Science & Business Media
Release Date : 1994-09-30
ISBN 10 : 9780306446108
Pages : 644 pages
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Highly fluorinated compounds; Fluorocarbon code numbers; HF problem; Synthesis of C-F bonds; Aliphatic fluorides go commercial; Perfluorocarbons; Wartime advances - the Manhatten project; Synthesis of organofluorine compounds; Characterictics of C-F systems; Perfluorocarbon fluids; Electrochemical fluorination; Chlorofluorocarbons (CFCs) and alternatives; Perfluoalkyl bromides and Iodides; Ring-fluorinated aromatic compounds; Side-chain fluorinated aromatic compounds routes to Benzotrifluorides; Recent developements in Fluorine-containing agrochemicals; Fluorinated liquid crystals; Fluorine-containing dyes; Textile finishes and fluorosurfactants; Fluorplastics; Fluoroelastomers; Fluoropolymer coatings; Fluorinated membranes; Monomers and polymers from Hexafluoroacetone; Perfluoropolethers (PFPEs); Surface fluorination of polymers; Fluorinated carbon; Fluorine in chemotherapy; Fluorinated inhalation anesthetics; Biomedical applications of Perfluorocarbons; Fluorochemical industry; CFCs and the environment.

Modern Fluoroorganic Chemistry
Author : Peer Kirsch
Publisher : John Wiley & Sons
Release Date : 2006-03-06
ISBN 10 : 3527604197
Pages : 320 pages
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In this handbook, Peer Kirsch clearly shows that this exciting field is no longer an exotic area of research. Aimed primarily at synthetic chemists wanting to gain a deeper understanding of the fascinating implications of including the highly unusual element fluorine in organic compounds, the main part of the book presents a wide range of synthetic methodologies and the experimental procedures selected undeniably show that this can be done with standard laboratory equipment. To round off, the author looks at fluorous chemistry and the applications of organofluorine compounds in liquid crystals, polymers and more besides. This long-awaited book represents an indispensable source of high quality information for everyone working in the field.

Organofluorine Chemistry
Author : B. Ameduri,V.V. Bardin
Publisher : Springer Science & Business Media
Release Date : 1997-09-18
ISBN 10 : 9783540631712
Pages : 244 pages
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The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.

Organofluorine Chemistry
Author : Kalman J. Szabo,Nicklas Selander
Publisher : John Wiley & Sons
Release Date : 2021-01-05
ISBN 10 : 3527825142
Pages : 464 pages
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By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

Organofluorine Chemistry
Author : Kenji Uneyama
Publisher : John Wiley & Sons
Release Date : 2008-04-15
ISBN 10 : 1405172932
Pages : 352 pages
GET BOOK!

The replacement of hydrogen with fluorine in organic molecules canprofoundly influence their chemical and physical properties,leading to a range of compounds with highly desirable properties.These molecules are of interest across the wide spectrum ofindustrial and academic organic chemistry, so that organofluorinechemistry is economically highly important. Organofluorine Chemistry will help chemists to develop a systematicknowledge of the chemistry of fluorine with a view towards itsapplication in the design of new reactions and syntheses, and thecreation of novel fluorinated molecules and materials. With initialchapters focusing on why fluorine creates such unique properties inorganic compounds, the book then covers general reactions offluorine. Coverage is chosen from the recent research literature,concentrating on the development of novel bioactive compounds andcatalytic ligands, and explaining, in the context of the initialchapters, how and why fluorine is so effective. With a finalchapter covering the general synthetic chemistry of organofluorinecompounds, the book is a cohesive summary of the fundamentalprincipals of organofluorine chemistry.

Handbook of Fluorous Chemistry
Author : John A. Gladysz,Dennis P. Curran,István T. Horváth
Publisher : John Wiley & Sons
Release Date : 2006-03-06
ISBN 10 : 3527604499
Pages : 624 pages
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Edited by the leading experts John Gladysz, Dennis Curran, and István Horváth, this handbook is the first to summarize all the essential aspects of this emerging field of chemistry. Whether the reader is seeking an introduction to the concept of fluorous biphase catalysis, summaries of partition coefficients involving fluorous and organic solvents, or information on the latest fluorous mixture separation techniques, this authoritative compilation of contributions, written by the world's top authors, provides key information needed for successfully working with the diverse and fascinating families of fluorous molecules. The large number of reliable experimental procedures in particular makes this the ideal guide for newcomers wanting to use this elegant method in the laboratory. In addition, experts will also find a wealth of important information concisely contained in one ready reference. The result is an indispensable resource for everyone currently working or intending to work in this field.

Fluorine in Organic Chemistry
Author : Richard D. Chambers
Publisher : CRC Press
Release Date : 2004
ISBN 10 : 9780849317903
Pages : 406 pages
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Replacing hydrogen with fluorine in organic molecules can profoundly influence their chemical and physical properties, leading to a range of chemical compounds, from Prozac to Teflon, which rely on organic fluorine chemistry for their useful and highly desirable properties. Fluorine in Organic Chemistry introduces its subject by discussing the chemical properties and electronic effects of fluorocarbon systems. Subsequent chapters detail the most efficient methods for the preparation and synthesis of partially, selectively, and highly fluorinated systems, from electrochemical flourination, to the addition of fluorine to olefins and aceytylenes. Other topics include: the characteristics of fluorocarbon groups in terms of ions, acids, and bases; substitution effects of fluorocarbon groups on nucleophilic displacement; elimination reactions; flouroalkane, functional, and polyfluoroaromatic compounds; fluorine in biochemistry; and organometallic reagents. With applications that extend from pharmaceuticals to fine and specialty chemicals to polymers, Fluorine in Organic Chemistry is an excellent reference for all organic chemists.

Studies in Organofluorine Chemistry
Author : Donald Richard Bellew
Publisher : N.A
Release Date : 1991
ISBN 10 :
Pages : 124 pages
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Fluorination
Author : Jinbo Hu,Teruo Umemoto
Publisher : Springer
Release Date : 2020-08-12
ISBN 10 : 9789811038952
Pages : 668 pages
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This volume reviews the recent advances in formation of C-F bonds and X-F bonds (X = heteroatom) to produce useful fluorinated molecules for pharmaceuticals, materials and more. Reactions and methods associated with fluorination, including monofluorination, difluorination, trifluorination and other polyfluorination that have emerged within the past few years are systematically discussed. With contributions from front-line researchers in this field from both academia and industry, this book provides a valuable resource for scholars, graduate students as well as professionals.

Fluorine Chemistry at the Millennium
Author : R.E. Banks
Publisher : Elsevier
Release Date : 2000-12-04
ISBN 10 : 9780080531793
Pages : 660 pages
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This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest. There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.

Modern Synthesis Processes and Reactivity of Fluorinated Compounds
Author : Henri Groult,Frederic Leroux,Alain Tressaud
Publisher : Elsevier
Release Date : 2016-11-04
ISBN 10 : 0128037903
Pages : 760 pages
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Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials. The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds. Contains quality content edited, and contributed, by leading scholars in the field Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics

Fluorine Chemistry at the Millennium
Author : R.E. Banks
Publisher : Elsevier
Release Date : 2000-12-04
ISBN 10 : 9780080531793
Pages : 660 pages
GET BOOK!

This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest. There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.

Fluorine in Pharmaceutical and Medicinal Chemistry
Author : Véronique Gouverneur
Publisher : World Scientific
Release Date : 2012
ISBN 10 : 1848166346
Pages : 546 pages
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Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.