numerical pde analysis of retinal neovascularization mathematical model computer implementation in r

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Numerical PDE Analysis of Retinal Neovascularization
Author : William E. Schiesser
Publisher : Academic Press
Release Date : 2019-06-14
ISBN 10 : 0128184531
Pages : 144 pages

Numerical PDE Analysis of Retinal Neovascularization Mathematical Model Computer Implementation in R provides a methodology for the analysis of neovascularization (formation of blood capillaries) in the retina. It describes the starting point—a system of three partial differential equations (PDEs)—that define the evolution of (1) capillary tip density, (2) blood capillary density and (3) concentration of vascular endothelial growth factor (VEGF) in the retina as a function of space (distance along the retina), x, and time, t, the three PDE dependent variables for (1), (2) and (3), and designated as u1(x, t), u2(x, t), u3(x, t), amongst other topics. Includes PDE routines based on the method of lines (MOL) for computer-based implementation of PDE models Offers transportable computer source codes for readers in R, with line-by-line code descriptions as it relates to the mathematical model and algorithms Authored by a leading researcher and educator in PDE models

Ocular Fluid Dynamics
Author : Giovanna Guidoboni,Alon Harris,Riccardo Sacco
Publisher : Springer Nature
Release Date : 2019-11-25
ISBN 10 : 3030258866
Pages : 612 pages

The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical modeling. Because each fluid receives a thorough analysis from experts in their respective fields, this volume stands out among the existing ophthalmology literature. Ocular Fluid Dynamics is ideal for current and future graduate students in applied mathematics and ophthalmology who wish to explore the field by investigating open questions, experimental technologies, and mathematical models. It will also be a valuable resource for researchers in mathematics, engineering, physics, computer science, chemistry, ophthalmology, and more.

Proceedings of the International Conference on Recent Cognizance in Wireless Communication & Image Processing
Author : Nitin Afzalpulkar,Vishnu Srivastava,Ghanshyam Singh,Deepak Bhatnagar
Publisher : Springer
Release Date : 2016-04-28
ISBN 10 : 8132226380
Pages : 1002 pages

This volume comprises the proceedings of the International Conference on Recent Cognizance in Wireless Communication & Image Processing. It brings together content from academicians, researchers, and industry experts in areas of Wireless Communication and Image Processing. The volume provides a snapshot of current progress in computational creativity and a glimpse of future possibilities. The proceedings include two kinds of paper submissions: (i) regular papers addressing foundation issues, describing original research on creative systems development and modeling; and (ii) position papers describing work-in-progress or research directions for computational creativity. This work will be useful to professionals and researchers working in the core areas of wireless communications and image processing.

High Resolution Imaging in Microscopy and Ophthalmology
Author : Josef F. Bille
Publisher : Springer
Release Date : 2019-08-13
ISBN 10 : 3030166384
Pages : 407 pages

This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Computer Vision for Biomedical Image Applications
Author : Yanxi Liu,Tianzi Jiang,China) Cvbia 200 (2005 Beijing,Changshui Zhang
Publisher : Springer Science & Business Media
Release Date : 2005-10-10
ISBN 10 : 9783540294115
Pages : 563 pages

This book constitutes the refereed proceedings of the First International Workshop on Computer Vision for Biomedical Image Applications: Current Techniques and Future Trends, CVBIA 2005, held in Beijing, China, in October 2005 within the scope of ICCV 20.

Ocular Disease: Mechanisms and Management E-Book
Author : Leonard A Levin,Daniel M. Albert
Publisher : Elsevier Health Sciences
Release Date : 2010-03-10
ISBN 10 : 0702047414
Pages : 704 pages

Ocular Disease—a newly introduced companion volume to the classic Adler’s Physiology of the Eye—correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert—two of the world’s leading ophthalmic clinician-scientists—have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color—with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. This comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment. Covers all areas of disease in ophthalmology including retina, cornea, cataract, glaucoma, and uveitis for the comprehensive information you need for managing clinical cases. Presents a unique and pragmatic blend of necessary basic science and clinical application to serve as a clinical guide to understanding the cause and rational management of ocular disease. Features 330 full-color line artworks that translate difficult concepts and discussions into concise schematics for improved understanding and comprehension. Provides the expert advice of internationally recognized editors with over 40 years of experience together with a group of world class contributors in basic science and clinical ophthalmology.

On the Power of Fuzzy Markup Language
Author : Giovanni Acampora,Vincenzo Loia,Chang-Shing Lee,Mei-Hui Wang
Publisher : Springer
Release Date : 2012-12-14
ISBN 10 : 3642354882
Pages : 188 pages

One of the most successful methodology that arose from the worldwide diffusion of Fuzzy Logic is Fuzzy Control. After the first attempts dated in the seventies, this methodology has been widely exploited for controlling many industrial components and systems. At the same time, and very independently from Fuzzy Logic or Fuzzy Control, the birth of the Web has impacted upon almost all aspects of computing discipline. Evolution of Web, Web2.0 and Web 3.0 has been making scenarios of ubiquitous computing much more feasible; consequently information technology has been thoroughly integrated into everyday objects and activities. What happens when Fuzzy Logic meets Web technology? Interesting results might come out, as you will discover in this book. Fuzzy Mark-up Language is a son of this synergistic view, where some technological issues of Web are re-interpreted taking into account the transparent notion of Fuzzy Control, as discussed here. The concept of a Fuzzy Control that is conceived and modeled in terms of a native web wisdom represents another step towards the last picture of Pervasive Web Intelligence.

Absolute Rheumatology Review
Author : Petros Efthimiou
Publisher : Springer Nature
Release Date : 2019-09-13
ISBN 10 : 3030230228
Pages : 478 pages

This book provides a concise and up-to-date review of key rheumatology topics along with extensive practice questions to assist in preparing for the American Board of Internal Medicine (ABIM) Rheumatology Certification Exam. Each chapter focuses on a single disease and starts with a short review (primarily tables and figures) to highlight the main points and key issues. The review is followed by 10-20 board-style multiple choice questions with detailed explanations for each topic. The chapters and associated preparation questions are written by established experts from top institutions in the United States. The book concludes with a 50-question practice test reflecting the format used by the ABIM Board Certification Exam. Absolute Rheumatology Review is an essential resource for not only graduate students, residents, and fellows in rheumatology and internal medicine studying for board exams but also rheumatologists, physicians, and related professionals preparing for recertification.

Adaptive Method of Lines
Author : A, Vande Wouwer,Ph. Saucez,W.E. Schiesser
Publisher : CRC Press
Release Date : 2001-04-18
ISBN 10 : 1420035614
Pages : 432 pages

The general Method of Lines (MOL) procedure provides a flexible format for the solution of all the major classes of partial differential equations (PDEs) and is particularly well suited to evolutionary, nonlinear wave PDEs. Despite its utility, however, there are relatively few texts that explore it at a more advanced level and reflect the method's current state of development. Written by distinguished researchers in the field, Adaptive Method of Lines reflects the diversity of techniques and applications related to the MOL. Most of its chapters focus on a particular application but also provide a discussion of underlying philosophy and technique. Particular attention is paid to the concept of both temporal and spatial adaptivity in solving time-dependent PDEs. Many important ideas and methods are introduced, including moving grids and grid refinement, static and dynamic gridding, the equidistribution principle and the concept of a monitor function, the minimization of a functional, and the moving finite element method. Applications addressed include shallow water flow, combustion and flame propagation, transport in porous media, gas dynamics, chemical engineering processes, solitary waves, and magnetohydrodynamics. As the first advanced text to represent the modern era of the method of lines, this monograph offers an outstanding opportunity to discover new concepts, learn new techniques, and explore a wide range of applications.

Advanced Techniques in Diagnostic Microbiology
Author : Yi-Wei Tang,Charles W. Stratton
Publisher : Springer Science & Business Media
Release Date : 2007-01-16
ISBN 10 : 0387328920
Pages : 540 pages

Clinical microbiologists are engaged in the field of diagnostic microbiology to determine whether pathogenic microorganisms are present in clinical specimens collected from patients with suspected infections. If microorganisms are found, these are identified and susceptibility profiles, when indicated, are determined. During the past two decades, technical advances in the field of diagnostic microbiology have made constant and enormous progress in various areas, including bacteriology, mycology, mycobacteriology, parasitology, and virology. The diagnostic capabilities of modern clinical microbiology laboratories have improved rapidly and have expanded greatly due to a technological revolution in molecular aspects of microbiology and immunology. In particular, rapid techniques for nucleic acid amplification and characterization combined with automation and user-friendly software have significantly broadened the diagnostic arsenal for the clinical microbiologist. The conventional diagnostic model for clinical microbiology has been labor-intensive and frequently required days to weeks before test results were available. Moreover, due to the complexity and length of such testing, this service was usually directed at the hospitalized patient population. The physical structure of laboratories, staffing patterns, workflow, and turnaround time all have been influenced profoundly by these technical advances. Such changes will undoubtedly continue and lead the field of diagnostic microbiology inevitably to a truly modern discipline. Advanced Techniques in Diagnostic Microbiology provides a comprehensive and up-to-date description of advanced methods that have evolved for the diagnosis of infectious diseases in the routine clinical microbiology laboratory. The book is divided into two sections. The first techniques section covers the principles and characteristics of techniques ranging from rapid antigen testing, to advanced antibody detection, to in vitro nucleic acid amplification techniques, and to nucleic acid microarray and mass spectrometry. Sufficient space is assigned to cover different nucleic acid amplification formats that are currently being used widely in the diagnostic microbiology field. Within each technique, examples are given regarding its application in the diagnostic field. Commercial product information, if available, is introduced with commentary in each chapter. If several test formats are available for a technique, objective comparisons are given to illustrate the contrasts of their advantages and disadvantages. The second applications section provides practical examples of application of these advanced techniques in several "hot" spots in the diagnostic field. A diverse team of authors presents authoritative and comprehensive information on sequence-based bacterial identification, blood and blood product screening, molecular diagnosis of sexually transmitted diseases, advances in mycobacterial diagnosis, novel and rapid emerging microorganism detection and genotyping, and future directions in the diagnostic microbiology field. We hope our readers like this technique-based approach and your feedback is highly appreciated. We want to thank the authors who devoted their time and efforts to produce their chapters. We also thank the staff at Springer Press, especially Melissa Ramondetta, who initiated the whole project. Finally, we greatly appreciate the constant encouragement of our family members through this long effort. Without their unwavering faith and full support, we would never have had the courage to commence this project.

Recent Trends in Image Processing and Pattern Recognition
Author : K. C. Santosh,Ravindra S. Hegadi
Publisher : Springer
Release Date : 2019-07-19
ISBN 10 : 9811391815
Pages : 717 pages

This three-book set constitutes the refereed proceedings of the Second International Conference on Recent Trends in Image Processing and Pattern Recognition (RTIP2R) 2018, held in Solapur, India, in December 2018. The 173 revised full papers presented were carefully reviewed and selected from 374 submissions. The papers are organized in topical sections in the tree volumes. Part I: computer vision and pattern recognition; machine learning and applications; and image processing. Part II: healthcare and medical imaging; biometrics and applications. Part III: document image analysis; image analysis in agriculture; and data mining, information retrieval and applications.

Biological, Physical and Technical Basics of Cell Engineering
Author : Gerhard M. Artmann,Aysegül Artmann,Azhar A. Zhubanova,Ilya Digel
Publisher : Springer
Release Date : 2018-04-11
ISBN 10 : 9811079048
Pages : 481 pages

This book presents and discusses recent scientific progress on Cell and Stem Cell Engineering. It predominantly focuses on Biological, Physical and Technical Basics, and features new trends of research reaching far into the 21st century.

Aging and Health - A Systems Biology Perspective
Author : A.I. Yashin,S.M. Jazwinski
Publisher : Karger Medical and Scientific Publishers
Release Date : 2014-10-09
ISBN 10 : 3318027308
Pages : 206 pages

Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.

Bioeffects and Therapeutic Applications of Electromagnetic Energy
Author : Riadh Habash
Publisher : CRC Press
Release Date : 2007-11-19
ISBN 10 : 9781420062854
Pages : 400 pages

From cell phones to treating cancer, EM energy plays a part in many of the innovations that we take for granted everyday. A basic force of nature, like nuclear energy or gravity, this energy can be harnessed and used, but still holds the potential to be harmful. The question remains, how safe are EM products? Bioeffects and Therapeutic Applications of Electromagnetic Energy provides a review of cutting-edge research in EM health effects and EM therapy along with emerging areas of bioengineering and biomedical engineering. The book allows you to · Understand the necessary EM theory in the context of its interaction with the human body · Review cutting-edge research on EM health effects and EM therapy · Explore techniques developed to ensure adequate EM and thermal dosimetry required for health effects and thermal therapy · Strengthen your understanding of the rapidly emerging areas of bioengineering and biomedical engineering Taking a transdisciplinary approach drawn from several intellectual streams that include physics, epidemiology, medicine, environment, risk assessment, and various disciplines of engineering, this book ventures into the conflicting studies to access research on bioeffects and therapeutic applications of EM energy. It is the only resource currently available that covers bioeffects and risk assessment of both extremely low frequency (ELF) fields and radiofrequency radiation (RFR) along with the recent developments in thermal therapy and imaging techniques.

Cancer Modelling and Simulation
Author : Luigi Preziosi
Publisher : CRC Press
Release Date : 2003-06-18
ISBN 10 : 9780203494899
Pages : 454 pages

Understanding how cancer tumours develop and spread is vital for finding treatments and cures. Cancer Modelling and Simulation demonstrates how mathematical modelling and computer simulation techniques are used to discover and gain insight into the dynamics of tumour development and growth. It highlights the benefits of tumour modelling, such as discovering optimal tumour therapy schedules, identifying the most promising candidates for further clinical investigation, and reducing the number of animal experiments. By examining the analytical, mathematical, and biological aspects of tumour growth and modelling, the book provides a common language and knowledge for professionals in several disciplines.

Single-Cell-Based Models in Biology and Medicine
Author : Alexander Anderson,Katarzyna Rejniak
Publisher : Springer Science & Business Media
Release Date : 2007-08-08
ISBN 10 : 376438123X
Pages : 349 pages

Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.

Recent Advances in Intelligent Informatics
Author : Sabu M. Thampi,Ajith Abraham,Sankar Kumar Pal,Juan Manuel Corchado Rodriguez
Publisher : Springer Science & Business Media
Release Date : 2013-07-30
ISBN 10 : 3319017780
Pages : 466 pages

This book constitutes the thoroughly refereed post-conference proceedings of the Second International Symposium on Intelligent Informatics (ISI 2013) held in Mysore, India during August 23-24, 2013. The 47 revised papers presented were carefully reviewed and selected from 126 initial submissions. The papers are organized in topical sections on pattern recognition, signal and image processing; data mining, clustering and intelligent information systems; multi agent systems; and computer networks and distributed systems. The book is directed to the researchers and scientists engaged in various fields of intelligent informatics.

Standard Handbook of Biomedical Engineering and Design
Author : Myer Kutz
Publisher : McGraw-Hill Professional Publishing
Release Date : 2003
ISBN 10 : 9780071356374
Pages : 1500 pages

THE HANDBOOK THAT BRIDGES THE GAP BETWEEN ENGINEERING PRINCIPLES AND BIOLOGICAL SYSTEMS The focus in the "Standard Handbook of Biomedical Engineering and Design" is on engineering design informed by description and analysis using engineering language and methodology. Over 40 experts from universities and medical centers throughout North America, the United Kingdom, and Israel have produced a practical reference for the biomedical professional who is seeking to solve a wide range of engineering and design problems, whether to enhance a diagnostic or therapeutic technique, reduce the cost of manufacturing a medical instrument or a prosthetic device, improve the daily life of a patient with a disability, or increase the effectiveness of a hospital department. Heavily illustrated with tables, charts, diagrams, and photographs, most of them original, and filled with equations and useful references, this handbook speaks directly to all practitioners involved in biomedical engineering, whatever their training and areas of specialization. Coverage includes not only fundamental principles, but also numerous recent advances in this fast moving discipline. Major sections include: * Biomedical Systems Analysis * Mechanics of the Human Body * Biomaterials * Bioelectricity * Design of Medical Devices and Diagnostic Instrumentation * Engineering Aspects of Surgery * Rehabilitation Engineering * Clinical Engineering The "Handbook" offers breadth and depth of biomedical engineering design coverage unmatched in any other general reference.

International Conference on Advancements of Medicine and Health Care through Technology; 12th - 15th October 2016, Cluj-Napoca, Romania
Author : Simona Vlad,Nicolae Marius Roman
Publisher : Springer
Release Date : 2017-04-13
ISBN 10 : 3319528750
Pages : 367 pages

This volume presents the contributions of the fifth International Conference on Advancements of Medicine and Health Care through Technology (Meditech 2016), held in in Cluj-Napoka, Romania. The papers of this Proceedings volume present new developments in - Health Care Technology, - Medical Devices, Measurement and Instrumentation, - Medical Imaging, Image and Signal Processing, - Modeling and Simulation, - Molecular Bioengineering, - Biomechanics.

Application of Biomedical Engineering in Neuroscience
Author : Sudip Paul
Publisher : Springer Nature
Release Date : 2019-11-19
ISBN 10 : 9811371423
Pages : 490 pages

This book focuses on interdisciplinary research in the field of biomedical engineering and neuroscience. Biomedical engineering is a vast field, ranging from bioengineering to brain-computer interfaces. The book explores the system-level function and dysfunction of the nervous system from scientific and engineering perspectives. The initial sections introduce readers to the physiology of the brain, and to the biomedical tools needed for diagnostics and effective therapies for various neurodegenerative and regenerative disorders. In turn, the book summarizes the biomedical interventions that are used to understand the neural mechanisms underlying empathy disorders, and reviews recent advances in biomedical engineering for rehabilitation in connection with neurodevelopmental disorders and brain injuries. Lastly, the book discusses innovations in machine learning and artificial intelligence for computer-aided disease diagnosis and treatment, as well as applications of nanotechnology in therapeutic neurology.