new targeting in the reversal of resistant glioblastomas

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New Targeting in The Reversal of Resistant Glioblastomas
Author : Ali Syed Arbab
Publisher : Academic Press
Release Date : 2021-03-18
ISBN 10 : 0128232765
Pages : 202 pages
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New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field. Explains the effect of bone marrow derived cells on the development of resistance to clinically practiced therapies Provides information on the availability of alternate therapies for recurrent glioblastoma when standard practices have failed Discusses targeting tumor microenvironment using available FDA approved drugs as an alternative treatment strategy for glioblastoma

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies
Author : Tarik F. Massoud,Ramasamy Paulmurugan
Publisher : Academic Press
Release Date : 2021-03-15
ISBN 10 : 9780128215678
Pages : 350 pages
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Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

Journal of the National Cancer Institute
Author : N.A
Publisher : N.A
Release Date : 1991
ISBN 10 :
Pages : 329 pages
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Cumulated Index Medicus
Author : N.A
Publisher : N.A
Release Date : 1995
ISBN 10 :
Pages : 329 pages
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Index Medicus
Author : N.A
Publisher : N.A
Release Date : 2004
ISBN 10 :
Pages : 329 pages
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Biomedical Index to PHS-supported Research
Author : N.A
Publisher : N.A
Release Date : 1992
ISBN 10 :
Pages : 329 pages
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Anticancer Research
Author : N.A
Publisher : N.A
Release Date : 1990
ISBN 10 :
Pages : 329 pages
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Pharmacotherapy
Author : N.A
Publisher : N.A
Release Date : 1996
ISBN 10 :
Pages : 329 pages
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Cancer Research
Author : N.A
Publisher : N.A
Release Date : 2008
ISBN 10 :
Pages : 329 pages
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Breast Cancer Management
Author : Lynda R. Wiseman
Publisher : Lippincott Williams & Wilkins
Release Date : 2000
ISBN 10 :
Pages : 133 pages
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Journal of the National Cancer Institute
Author : N.A
Publisher : N.A
Release Date : 1996
ISBN 10 :
Pages : 329 pages
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"Summaries of papers" contained in the journal accompany each issue, 19--

Cancer Drug Resistance
Author : Jose Rueff,António Sebastião Rodrigues
Publisher : Humana Press
Release Date : 2016-02-25
ISBN 10 : 9781493933457
Pages : 314 pages
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This volume discusses the latest advancements and technologies used in cancer drug resistance research. Cancer Drug Resistance: Overviews and Methods contains chapters that cover topics such as: studying the mechanics of resistance to DNA damaging therapeutic drugs; studies to delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; the role of microRNAs in current pancreatic cancer treatment; and cancer exosomes as mediators of drug resistance or clinical and molecular methods in drug development and the use of bioinformatics in the management of cancer drug resistance data. Written in the highly successful Methods in Molecular Biology series format, chapters include overviews of the main issues in cancer drug resistance and the respective mechanisms, as well as introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Drug Resistance: Overviews and Methods, is a valuable resource to researchers, oncobiologists and clinical oncologists or anyone else who is interested in the study of cancer and its drug resistances.