neurotherapeutics in the era of translational medicine

Download Neurotherapeutics In The Era Of Translational Medicine ebooks in PDF, epub, tuebl, textbook from Skinvaders.Com. Read online Neurotherapeutics In The Era Of Translational Medicine books on any device easily. We cannot guarantee that Neurotherapeutics In The Era Of Translational Medicine book is available. Click download or Read Online button to get book, you can choose FREE Trial service. READ as many books as you like (Personal use).

Neurotherapeutics in the Era of Translational Medicine
Author : Richard A. Smith,Brian K. Kaspar,Clive N. Svendsen
Publisher : Academic Press
Release Date : 2020-11-28
ISBN 10 : 0128172746
Pages : 518 pages
GET BOOK!

For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis‎, spinal muscular atrophy, multiple sclerosis, Parkinson’s disease, myasthenia gravis, migraine, and glioblastoma. The "story behind the story" of these translational efforts is told, with authors depicting the ups and downs encountered on the path of their drug discovery and development effort. In parallel with this path, advances in identifying novel biomarkers and disease models are summarized, as are contemporary issues focusing on clinical trial design, bioethics, innovative funding strategies, and collaborations between government and academia in an effort to facilitate breakthrough treatments. The book is written by members of the biotech and pharmaceutical ecosystem for those who belong to it and aspire to become part of it. Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders Discusses important issues in clinical trials such as design and ethical issues Written for neuroscientists, neurologists and pharmacologists

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2007: Testimony of members of Congress and other interested individuals and organizations
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : N.A
Release Date : 2006
ISBN 10 :
Pages : 329 pages
GET BOOK!

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2007
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : N.A
Release Date : 2006
ISBN 10 :
Pages : 329 pages
GET BOOK!

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness
Author : Anne Harrington
Publisher : W. W. Norton & Company
Release Date : 2019-04-16
ISBN 10 : 1324001976
Pages : 384 pages
GET BOOK!

Mind Fixers tells the history of psychiatry’s quest to understand the biological basis of mental illness and asks where we need to go from here. In Mind Fixers, Anne Harrington, author of The Cure Within, explores psychiatry’s repeatedly frustrated struggle to understand mental disorder in biomedical terms. She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds. But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time. Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well. In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones. A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

Encyclopedia of Tissue Engineering and Regenerative Medicine
Author : N.A
Publisher : Academic Press
Release Date : 2019-06-04
ISBN 10 : 0128137002
Pages : 1418 pages
GET BOOK!

Encyclopedia of Tissue Engineering and Regenerative Medicine provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the fields of tissue engineering and regenerative medicine Contains multimedia features, including hyperlinked references and further readings, cross-references and diagrams/images Represents the most comprehensive and exhaustive product on the market on the topic

Genetics of Epilepsy
Author : N.A
Publisher : Elsevier
Release Date : 2014-09-04
ISBN 10 : 0444633332
Pages : 346 pages
GET BOOK!

The book chapters cover different aspects of epilepsy genetics, starting with the "classical" concept of epilepsies as ion channel disorders. The second part of the book gives credit to the fact that by now non-ion channel genes are recognized as equally important causes of epilepsy. The concluding chapters are designed to offer the reader insight into current methods in epilepsy research. Each chapter is self-contained and deals with a selected topic of interest. Authors are the leading experts in the field of epilepsy research Book covers the most important aspects of epilepsy Interesting for both scientists and clinicians

Surgical Neuro-Oncology
Author : Russell R. Lonser,J. Bradley Elder
Publisher : Neurosurgery by Example
Release Date : 2018-11-09
ISBN 10 : 0190696699
Pages : 312 pages
GET BOOK!

Part of the Neurosurgery by Example series, this volume on surgical neuro-oncology presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore a number of different types of nervous systems tumors, including glioblastoma, medulloblastoma, skull tumors, and more. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Surgical Neuro-Oncology is appropriate for neurosurgeons who wish to learn more about this subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

Visually Memorable Neuroanatomy for Beginners
Author : Min Suk Chung,Beom Sun Chung
Publisher : Academic Press
Release Date : 2020-07-04
ISBN 10 : 012819913X
Pages : 198 pages
GET BOOK!

Visually Memorable Neuroanatomy for Beginners takes a close look at the anatomy of the human brain and teaches readers to identify and examine its structures in a relatable way. Unlike large textbooks that deliver a superficial overview of the subject, this book explores the anatomy and physiology of the brain using mnemonic techniques and informative comic figures that present brain regions at an introductory level, allowing readers to easily identify different parts of the brain. This volume is appropriate for undergraduate and graduate students, postdoctoral fellows, and researchers in the medicine, health sciences, and biological sciences. Beginning with the morphology of the brain and spinal cord, this book then explores the somatic nerve and autonomic nerve, the cranial nerve and spinal nerve, the function of the brain, and concludes with the development of the nervous system. Features simplified illustrations for understanding the complicated neuroanatomy structures Introduces memorizing tips (mnemonics) to help students learn Describes how best to identify structures in cadaver specimens Includes comic-style figures to make neuroanatomy approachable for newcomers

The Senses: A Comprehensive Reference
Author : N.A
Publisher : Academic Press
Release Date : 2020-09-30
ISBN 10 : 0128054093
Pages : 5208 pages
GET BOOK!

The Senses: A Comprehensive Reference, Second Edition, is a comprehensive reference work covering the range of topics that constitute current knowledge of the neural mechanisms underlying the different senses. This important work provides the most up-to-date, cutting-edge, comprehensive reference combining volumes on all major sensory modalities in one set. Offering 264 chapters from a distinguished team of international experts, The Senses lays out current knowledge on the anatomy, physiology, and molecular biology of sensory organs, in a collection of comprehensive chapters spanning 4 volumes. Topics covered include the perception, psychophysics, and higher order processing of sensory information, as well as disorders and new diagnostic and treatment methods. Written for a wide audience, this reference work provides students, scholars, medical doctors, as well as anyone interested in neuroscience, a comprehensive overview of the knowledge accumulated on the function of sense organs, sensory systems, and how the brain processes sensory input. As with the first edition, contributions from leading scholars from around the world will ensure The Senses offers a truly international portrait of sensory physiology. The set is the definitive reference on sensory neuroscience and provides the ultimate entry point into the review and original literature in Sensory Neuroscience enabling students and scientists to delve into the subject and deepen their knowledge. All-inclusive coverage of topics: updated edition offers readers the only current reference available covering neurobiology, physiology, anatomy, and molecular biology of sense organs and the processing of sensory information in the brain Authoritative content: world-leading contributors provide readers with a reputable, dynamic and authoritative account of the topics under discussion Comprehensive-style content: in-depth, complex coverage of topics offers students at upper undergraduate level and above full insight into topics under discussion

Pain Management and the Opioid Epidemic
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publisher : National Academies Press
Release Date : 2017-09-28
ISBN 10 : 0309459575
Pages : 482 pages
GET BOOK!

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Regenerative Pharmacology
Author : George J. Christ,Karl-Erik Andersson
Publisher : Cambridge University Press
Release Date : 2013-04-15
ISBN 10 : 1107354730
Pages : 329 pages
GET BOOK!

Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Translational Regenerative Medicine
Author : Anthony Atala,Julie Allickson
Publisher : Academic Press
Release Date : 2014-12-01
ISBN 10 : 0124104576
Pages : 606 pages
GET BOOK!

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Clinical Neuroanatomy, 28th Edition
Author : Stephen G. Waxman
Publisher : McGraw Hill Professional
Release Date : 2017-04-22
ISBN 10 : 0071847715
Pages : 384 pages
GET BOOK!

A concise, highly visual overview of neuroanatomy and its functional underpinnings Clinical Neuroanatomy, Twenty-Eighth Edition offers an accessible, easy-to-remember synopsis of neuroanatomy and its functional and clinical implications. Since many of us learn and remember better when material is presented visually, this acclaimed resource includes not only clinical material such as brain scans and pathological specimens, but also hundreds of diagrams and tables that are designed to be clear and memorable. Here's why Clinical Neuroanatomy is essential for board review or as a clinical refresher: • NEW SECTION summarizes the most important take-away lessons from each chapter • More than 300 full-color illustrations • A unique chapter on Introduction to Clinical Thinking puts neuroanatomy in clear clinical perspective • Numerous CT and MRI scans • Block diagrams illustrate actions of each muscle (essential for the clinical motor examination) • Hundreds of diagrams and tables encapsulate important information • Essentials for the Clinical Neuroanatomist list appears in each chapter • Clear and memorable root-by-root and nerve-by-nerve illustrations of sensory areas and muscle intervention • Coverage of the basic structure and function of the brain, spinal cord, and peripheral nerves as well as clinical presentations of disease processes involving specific structures • Emphasizes must-know concepts, facts, and structures • Appendices include The Neurologic Examination, Testing Muscle Function, Spinal Nerves and Plexuses, and Questions and Answers • Case studies demonstrate how concepts apply to real-world situations If your practice or education would benefit from an engagingly written, well-illustrated overview of neuroanatomy and its functional underpinnings, this trusted resource belongs on your desk.

Nervous System Drug Delivery
Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
Publisher : Academic Press
Release Date : 2019-06-25
ISBN 10 : 0128139986
Pages : 556 pages
GET BOOK!

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry

The Neurobiology of Childhood
Author : Susan L. Andersen,Daniel S. Pine
Publisher : Springer
Release Date : 2014-05-13
ISBN 10 : 3642549136
Pages : 370 pages
GET BOOK!

During the past years there has been rapid progress in the understanding of how early life stress impacts psychopathology in children. The first two parts of this book present the basic principles of brain development and describe the most important neuronal systems. This includes systems involved in emotion processing, cognitive control, and social processes. These first two general sections are followed by an overview about recent research on various neuronal and psychiatric disorders, where environmental exposures and altered brain development play an important role: sleep, autism, ADHD and other developmental forms of psychopathology.

Emerging Cognitive Neuroscience and Related Technologies
Author : National Research Council,Division on Behavioral and Social Sciences and Education,Board on Behavioral, Cognitive, and Sensory Sciences,Division on Engineering and Physical Sciences,Standing Committee for Technology Insight--Gauge, Evaluate, and Review,Committee on Military and Intelligence Methodology for Emergent Neurophysiological and Cognitive/Neural Science Research in the Next Two Decades
Publisher : National Academies Press
Release Date : 2008-12-06
ISBN 10 : 0309118948
Pages : 214 pages
GET BOOK!

Emerging Cognitive Neuroscience and Related Technologies, from the National Research Council, identifies and explores several specific research areas that have implications for U.S. national security, and should therefore be monitored consistently by the intelligence community. These areas include: neurophysiological advances in detecting and measuring indicators of psychological states and intentions of individuals the development of drugs or technologies that can alter human physical or cognitive abilities advances in real-time brain imaging breakthroughs in high-performance computing and neuronal modeling that could allow researchers to develop systems which mimic functions of the human brain, particularly the ability to organize disparate forms of data. As these fields continue to grow, it will be imperative that the intelligence community be able to identify scientific advances relevant to national security when they occur. To do so will require adequate funding, intelligence analysts with advanced training in science and technology, and increased collaboration with the scientific community, particularly academia. A key tool for the intelligence community, this book will also be a useful resource for the health industry, the military, and others with a vested interest in technologies such as brain imaging and cognitive or physical enhancers.

Evidence-based Psychotherapy
Author : Carol D. Goodheart,Alan E. Kazdin,Robert J. Sternberg
Publisher : Amer Psychological Assn
Release Date : 2006
ISBN 10 :
Pages : 295 pages
GET BOOK!

This book engages the voices of a broad range of clinical researchers, practitioners, educators, and public policy advocates in a comprehensive discussion of the spectrum of issues and arguments in the current debate about EBP.

The Biopsychosocial Model of Health and Disease
Author : Derek Bolton,Grant Gillett
Publisher : Springer
Release Date : 2019-03-28
ISBN 10 : 3030118991
Pages : 149 pages
GET BOOK!

This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.

Warlow's Stroke
Author : Graeme J. Hankey,Malcolm Macleod,Philip B. Gorelick,Christopher Chen,Fan Z. Caprio,Heinrich Mattle
Publisher : John Wiley & Sons
Release Date : 2019-01-22
ISBN 10 : 1118492420
Pages : 1008 pages
GET BOOK!

A practical textbook, based on a problem-oriented workflow, that will improve patients' likelihood of full recovery from stroke and prevent future strokes from occurring Stroke is the leading cause of adult disability and is in the top five causes of death globally. Warlow's Stroke: Practical Management, 4th Edition takes a problem-oriented approach and addresses the questions posed by a stroke patient in the order they are likely to present in clinical practice, for instance, 'Is it a stroke?', 'What sort of stroke?', 'What caused it?', and 'What can be done about it?'. Beginning with chapters phrased as questions, the book walks the reader through a standard clinical workflow, exploring the practical skills and assessment required at each stage of patient management. Early chapters cover: locating the vascular lesion, identifying the involved arterial territory, the role imaging should play, and the application thereof. Subsequent chapters look at what causes a transient or persistent ischemic event, an intracerebral hemorrhage and a subarachnoid hemorrhage. Unusual causes of ischemic stroke and transient ischemic attack are also covered. The book then presents a practical approach to the management of stroke and transient ischemic attack; offers specific treatments for acute ischemic stroke and aneurysmal subarachnoid hemorrhage; provides ways for professionals to prevent first or recurrent stroke; and more. Final chapters of the book discuss rehabilitation after stroke, how patients and carers can be supported in the short term and long term, prevention of recurrent stroke, and the organization of stroke services. Warlow's Stroke: Practical Management, 4th Edition Follows clinical workflow for stroke analysis Features evidence-based approach throughout Offers practical application aimed at improving patient outcomes Written and edited by internationally renowned experts in the field An essential resource for all practitioners involved in the care of patients who suffer from cerebrovascular disease, but particularly suitable for neurologists, residents, geriatricians, stroke physicians, radiologists and primary care physicians.

Practical Guide to Transcranial Direct Current Stimulation
Author : Helena Knotkova,Michael A. Nitsche,Marom Bikson,Adam J. Woods
Publisher : Springer
Release Date : 2019-01-23
ISBN 10 : 3319959484
Pages : 651 pages
GET BOOK!

This book provides a comprehensive overview on Transcranial Direct Current Stimulation (tDCS) and the clinical applications of this promising technique. Separated into three parts, the book begins with basic principles, mechanisms and approaches of tDCS. This is followed by a step-by-step practicum, methodological considerations and ethics and professional conduct pertaining to this novel technique. Chapters are authored by renowned experts who also direct and plan tDCS educational events worldwide. Bridging the existing gap in instructional materials for tDCS while addressing growing interest in education in this field, professionals within a broad range of medical disciplines will find this text to be an invaluable guide.