The second edition of Nanotechnology in Biology and Medicine is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in life sciences. This technology, which is on the scale of molecules, has enabled the development of devices smaller and more efficient than anything currently available. To understand complex biological nanosystems at the cellular level, we urgently need to develop a next-generation nanotechnology tool kit. It is believed that the new advances in genetic engineering, genomics, proteomics, medicine, and biotechnology will depend on our mastering of nanotechnology in the coming decades. The integration of nanotechnology, material sciences, molecular biology, and medicine opens the possibility of detecting and manipulating atoms and molecules using nanodevices, which have the potential for a wide variety of biological research topics and medical uses at the cellular level. This book presents the most recent scientific and technological advances of nanotechnology for use in biology and medicine. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a collection of published data with an extensive list of references for further details. The goal of this book is to provide a comprehensive overview of the most recent advances in instrumentation, methods, and applications in areas of nanobiotechnology, integrating interdisciplinary research and development of interest to scientists, engineers, manufacturers, teachers, and students.
The combination of biology and nanotechnology has led to a new generation of nanodevices that make it possible to characterize the chemical, mechanical, and other molecular properties, as well as discover novel phenomena and biological processes occurring at the molecular level. These advances provide science with a wide range of tools for biomedical applications in therapeutic, diagnostic, and preventive medicine. Nanotechnology in Biology and Medicine: Methods, Devices, and Applications integrates interdisciplinary research and recent advances in instrumentation and methods for applying nanotechnology to various areas in biology and medicine. Pioneers in the field describe the design and use of nanobiosensors with various analytical techniques for the detection and monitoring of specific biomolecules, including cancer cells. The text focuses on the design of novel bio-inspired materials, particularly for tissue engineering applications. Each chapter provides introductory material including a description of methods, protocols, instrumentation, and applications, as well as a collection of published data with an extensive list of references. An authoritative reference written for a broad audience, Nanotechnology in Biology and Medicine: Methods, Devices, and Applications provides a comprehensive forum that integrates interdisciplinary research to present the most recent advances in protocols, methods, instrumentation, and applications of nanotechnology in biology and medicine.
This text book will bring together a mix of both internationally known and established senior scientists along side up and coming (but already accomplished) junior scientists that have varying expertise in fundamental and applied nanotechnology to biology and medicine.
The nanotechnology revolution that will transform human health and longevity Nano Comes to Life opens a window onto the nanoscale—the infinitesimal realm of proteins and DNA where physics and cellular and molecular biology meet—and introduces readers to the rapidly evolving nanotechnologies that are allowing us to manipulate the very building blocks of life. Sonia Contera gives an insider's perspective on this new frontier, revealing how nanotechnology enables a new kind of multidisciplinary science that is poised to give us control over our own biology, our health, and our lives. Drawing on her perspective as one of today's leading researchers in the field, Contera describes the exciting ways in which nanotechnology makes it possible to understand, interact with, and manipulate biology—such as by designing and building artificial structures and even machines at the nanoscale using DNA, proteins, and other biological molecules as materials. In turn, nanotechnology is revolutionizing medicine in ways that will have profound effects on our health and longevity, from nanoscale machines that can target individual cancer cells and deliver drugs more effectively, to nanoantibiotics that can fight resistant bacteria, to the engineering of tissues and organs for research, drug discovery, and transplantation. The future will bring about the continued fusion of nanotechnology with biology, physics, medicine, and cutting-edge fields like robotics and artificial intelligence, ushering us into a new "transmaterial era." As we contemplate the power, advantages, and risks of accessing and manipulating our own biology, Contera offers insight and hope that we may all share in the benefits of this revolutionary research.
Bio-nanotechnology is the key functional technology of the 21stcentury. It is a fusion of biology and nanotechnology based on theprinciples and chemical pathways of living organisms, and refers tothe functional applications of biomolecules in nanotechnology. Itencompasses the study, creation, and illumination of theconnections between structural molecular biology, nutrition andnanotechnology, since the development of techniques ofnanotechnology might be guided by studying the structure andfunction of the natural nano-molecules found in living cells.Biology offers a window into the most sophisticated collection offunctional nanostructures that exists. This book is a comprehensive review of the state of the art inbio-nanotechnology with an emphasis on the diverse applications infood and nutrition sciences, biomedicine, agriculture and otherfields. It describes in detail the currently available methods andcontains numerous references to the primary literature, making thisthe perfect “field guide” for scientists who want toexplore the fascinating world of bio-nanotechnology. Safety issuesregarding these new technologies are examined in detail. The book is divided into nine sections – an introductorysection, plus: Nanotechnology in nutrition and medicine Nanotechnology, health and food technology applications Nanotechnology and other versatile applications Nanomaterial manufacturing Applications of microscopy and magnetic resonance innanotechnology Applications in enhancing bioavailability and controllingpathogens Safety, toxicology and regulatory aspects Future directions of bio-nanotechnology The book will be of interest to a diverse range of readers inindustry, research and academia, including biologists, biochemists,food scientists, nutritionists and health professionals.
The modern fascination with micro- and nano-sized materials can actually be traced back further to the 1960s and ‘70s when the first few reported attempts were made to use nanoparticles for controlled drug delivery. In Nanoparticles in Biology and Medicine: Methods and Protocols, experts in the field present a wide range of methods for synthesis, surface modification, characterization, and application of nano-sized materials (nanoparticles) in life science and medical fields, mostly for drug delivery. The methods presented cover all stages of nanoparticle manufacturing, modification, analysis, and applications. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Nanoparticles in Biology and Medicine: Methods and Protocols will help the beginner become familiar with this fascinating field and will provide scientists at all levels of expertise with easy-to-follow practical advice needed to make, modify, and analyze nanoparticles of their choice and to use them in a wide range of biomedical and pharmaceutical applications, including functional protein studies, drug delivery, immunochemistry, imaging, and many others.
Considering the fluid nature of nano breakthroughs—and the delicate balance between benefits and consequences as they apply to medicine—readers at all levels require a practical, understandable base of information about these developments to take greatest advantage of them. Medical Nanotechnology and Nanomedicine meets that need by introducing non-experts to nanomedicine and its evolving organizational infrastructure. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects—an ideal foundation upon which to plan and make decisions. Covers the use of nanotechnology in medical applications including imaging, diagnosis and monitoring, drug delivery systems, surgery, tissue regeneration, and prosthetics Part of the Perspectives in Nanotechnology series—which contains broader coverage of the societal implications of nanotechnology—this book can be used as a standalone reference. Organized by historical perspective, current status, and future prospects, this powerful book: Explores background, definitions and terms, and recent trends and forces in nanomedicine Surveys the landscape of nanomedicine in government, academia, and the private sector Reviews projected future directions, capabilities, sustainability, and equity of nanomedicine, and choices to be made regarding its use Includes graphical illustrations, references, and keywords to reinforce concepts and aid further research In its assessment of alternative and sometimes conflicting concepts proposed for the application of nanotechnology to medicine, this book surveys major initiatives and the work of leading labs and innovators. It uses informative examples and case summaries to illustrate proven accomplishments and imagined possibilities in research and development.
|Author||: Michael Giersig,Gennady B. Khomutov|
|Publisher||: Springer Science & Business Media|
|Release Date||: 2008-01-03|
|ISBN 10||: 1402068298|
|Pages||: 187 pages|
This book unites the multi-faceted work of international scientists from various domains as they cooperate to present the role of nanomaterials in modern medicine with particular emphasis on cell growth, manipulation, and modification. Not only does this book provide the reader with the necessary theoretical background information, it also gives valuable experimental data, allowing for an exact comprehension and observation of the relevance of this modern technology.
Nanotechnology plays a key leading role in developing tools able to identify, measure, and study cellular events at the nanometric level as well as in contributing to the disclosure of unknown biological interactions and mechanisms, which opens the door for advances including nanodevices for diagnostic and therapy, drug delivery systems, and regenerative medicine. In Nanotechnology in Regenerative Medicine: Methods and Protocols, expert researchers in the field provide an overview of a very wide range of currently used technologies and methods that involve nanotechnology principles applicable to tissue regeneration. Being that the application of nanotechnology to regenerative medicine is a very broad field, this book focuses its interests on particular areas such as its use as a means to produce efficient platforms and structures for tissue engineering, delivery systems and biosensors, as well as the use of some techniques to study materials surfaces and the interactions between cells, biomolecules, and surfaces at the nanoscale. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their related topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Nanotechnology in Regenerative Medicine: Methods and Protocols provides established scientists, junior researchers, and students involved in the bioengineering, biotechnology, and biomedical fields with a sound foundation in a variety of vital nanotechnology approaches in regenerative medicine.
The rapidly developing field of nanomaterials has expanded in many commercial areas. More recent studies have begun to provide a foundation for understanding how nanomaterials influence cells and how they also can serve as methodological tools for studies in medicine and cell biology, including research into stem cells. Recent investigations have shown affects of nanomaterials on specific subcellular structures, such as the actin-based brush border network in cells with an increasing emphasis on the barrier function of epithelial tissues. While other studies have shown involvement of nanoparticles in specific cytoplasmic signal transduction events such as the rise in intracellular free calcium, a signaling event known to regulate many changes in cell architecture and function. In parallel, nanomaterials are increasingly used in medicine for drug delivery, treatment of cancer and an increasing number of new applications. This book investigates these areas and also includes new methods for assessment in cell biology and medicine.
|Author||: Noam Eliaz|
|Publisher||: Springer Science & Business Media|
|Release Date||: 2011-08-23|
|ISBN 10||: 9781461403470|
|Pages||: 425 pages|
The study of electrochemical nanotechnology has emerged as researchers apply electrochemistry to nanoscience and nanotechnology. These two related volumes in the Modern Aspects of Electrochemistry Series review recent developments and breakthroughs in the specific application of electrochemistry and nanotechnology to biology and medicine. Internationally renowned experts contribute chapters that address both fundamental and practical aspects of several key emerging technologies in biomedicine, such as the processing of new biomaterials, biofunctionalization of surfaces, characterization of biomaterials, discovery of novel phenomena and biological processes occurring at the molecular level.
Nanoparticles are considered to be the building blocks for nanotechnology and are referred to as the particles having more than one dimension of the order of 100 nm or less.The nanostructured materials are being offered as better built, long lasting, cleaner, safer, and smarter products for use in communications, medicine, transportation, agriculture and other industries. Topics in molecular recognition, biomolecule-nanocrystal conjugates as fluorescence label for biological cells, and DNA-mediated groupings of nanocrystals are widespread, intriguing researchers from both biological and engineering fields. The diversity of nanotechnology covers fields from biology to material science, physics to chemistry, and other fields with variety of specialties. Controlled size, shape, composition, crystallinity, and structure-dependent properties of nanoparticles govern the unique properties of nanotechnology. The controlled biosynthesis of nanoparticles is of high scientific and technological interest as the microorganisms grab target ions from their environment and then turn the metal ions into the element metal through enzymatic mechanism generated through their cellular (Intra/ Extra) activities. The project aims to introduce the basics and advancements made so far in the field of biosynthesis of nanoparticles for graduate students and researchers around the world. The main aims are to (a) introduce the reader to the variety of microorganisms and their ability to synthesize the nanoparticles, (b) provide an overview of the methodologies applied to biosynthesize the variety of nanoparticles of medical and commercial uses, (c) provide a literature review on diversity of microorganisms able to synthesize nanoparticles of different types, (d) to discuss the regulatory mechanisms in microorganism able to synthesize variety of nanoparticles, (e) discuss experimental design problems associated with the controlled biosynthesis of nanoparticles, (f) discuss the stability and toxicity of nanoparticles in varying environment towards their therapeutic implications. The regulations, challenges and implications of biosynthesized nanoparticles for commercial significance will also represent among the main sections of the book. These aims will be organized by invited research/ review articles from renowned researchers exploring biosynthesis of variety of nanoparticles, and differ in length and number of chapters, with the literature review section containing the bulk of the text.