nanotechnology based targeted drug delivery systems for lung cancer

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Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer
Author : Prashant Kesharwani
Publisher : Academic Press
Release Date : 2019-01-26
ISBN 10 : 0128163674
Pages : 340 pages
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Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer
Author : Prashant Kesharwani
Publisher : Academic Press
Release Date : 2019-02-15
ISBN 10 : 9780128157206
Pages : 340 pages
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Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors
Author : Prashant Kesharwani,Umesh Gupta
Publisher : Academic Press
Release Date : 2018-04-10
ISBN 10 : 9780128122181
Pages : 466 pages
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Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors
Author : Prashant Kesharwani,Umesh Gupta
Publisher : Academic Press
Release Date : 2018-04-20
ISBN 10 : 0128122498
Pages : 478 pages
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Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors

Nano Medicine and Nano Safety
Author : Malay K. Das
Publisher : Springer Nature
Release Date :
ISBN 10 : 9811562555
Pages : 329 pages
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Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy
Author : Muhammad Raza Shah,Muhammad Imran,Shafi Ullah
Publisher : Elsevier
Release Date : 2019-07-13
ISBN 10 : 0128163119
Pages : 310 pages
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Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites. This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment. Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers

Nano Drug Delivery Strategies for the Treatment of Cancers
Author : Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Publisher : Academic Press
Release Date : 2020-09-03
ISBN 10 : 0128197943
Pages : 374 pages
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Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Application of Nanotechnology in Drug Delivery
Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Release Date : 2014-07-25
ISBN 10 : 9535116282
Pages : 554 pages
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This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems
Author : Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams
Publisher : Academic Press
Release Date : 2020-08-04
ISBN 10 : 0128208880
Pages : 616 pages
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Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Nano Drug Delivery Strategies for the Treatment of Cancers
Author : Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Publisher : Academic Press
Release Date : 2020-09-16
ISBN 10 : 0128197935
Pages : 376 pages
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Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Smart Drug Delivery System
Author : Ali Demir Sezer
Publisher : BoD – Books on Demand
Release Date : 2016-02-10
ISBN 10 : 9535122479
Pages : 398 pages
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This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management
Author : Aamir Ahmad,Shirish M. Gadgeel
Publisher : Springer
Release Date : 2015-12-24
ISBN 10 : 3319249320
Pages : 231 pages
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This, the second of two volumes on personalized medicine in lung cancer, touches upon the recent progress in targeted drug development based on genomics; emerging biomarkers and therapeutic targets such as EMT, cancer stem cells, and the tumor microenvironment; current personalized clinical management and radiation therapy for lung cancers; and the promise of epigenetics and next-generation sequencing for the advancements towards personalized therapy of lung cancer patients. With chapters on state-of-the-art therapies and technologies written by leading experts working to develop novel companion diagnosis tools for the personalized treatment of lung cancer patients, this volume brings readers up-to-date by presenting the current knowledge on the efforts to make personalized management of lung cancer patients a reality.

Nanoparticles in Lung Cancer Therapy - Recent Trends
Author : Abhijit Bandyopadhyay,Tamalika Das,Sabina Yeasmin
Publisher : Springer
Release Date : 2014-11-14
ISBN 10 : 8132221753
Pages : 65 pages
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This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early stage. Currently, lung cancer is the subject of major concern owing to the very high mortality rate throughout the world. Most of the conventional treatment methods such as surgery, chemotherapy, radiotherapy, etc., fail to prolong life of the patients. Incidents of recurrence are also very common in case of lung cancer. Researchers have shown that nanoparticles may act as a powerful anti cancer tool, especially for lung cancer. Unique surface properties and easy surface functionalization of nanoparticles enable early detection, diagnosis, imaging and treatment of lung cancer. The authors have elaborately presented how various nanoparticles (natural, semi synthetic and synthetic) may help in the treatment of lung cancer. They have also detailed works of various scientists who succeeded in developing effective nanoparticles and enabled very specific lung cancer therapy without any undesirable side effects and minimized death.

Targeted Drug Delivery : Concepts and Design
Author : Padma V. Devarajan,Sanyog Jain
Publisher : Springer
Release Date : 2014-12-08
ISBN 10 : 3319113550
Pages : 790 pages
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This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Nanotechnology Applications for Cancer Chemotherapy
Author : Sanyog Jain,Kaisar Raza,Ashish Kumar Agrawal,Ankur Vaidya
Publisher : Elsevier
Release Date : 2020-10-01
ISBN 10 : 0128178477
Pages : 702 pages
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Applications of Nanotechnology in Cancer Chemotherapy offers a complete and concise summary of nanotechnological interventions for cancer management. It highlights the basics of oncology, the cancer microenvironment, targets for active drug delivery, the underlying mechanisms and molecular pathways to enhance the drug delivery to the cancer site. The book discusses the principles of basic and innovative nanocarrier-based therapeutic approaches to modulate the progression of the disease. In addition, this book also explores the evolving targeting approaches specific to the cancer site and type. The scope of the book is not limited to targeted drug delivery for various cancers, but also explores the advancements in cancer imaging and diagnostics employing the nanotechnological tools. Emphasis has been given on the important evaluation techniques like in-vitro cell culture and in-vivo animal models to assess the performance of cancer nanomedicines. The book includes clinical study reports of various drug moieties explored using variety of nanoconstructs in myriad cancer conditions with the input of global market and pharmacoeconomics. Discusses how organic and inorganic nanoplatforms are being used in cancer treatment Shows how nanotechnology is being used to create new and more accurate diagnostic tools Surveys the current generation of cancer nanomedicines, assessing their advantages and challenges

Surface Modification of Nanoparticles for Targeted Drug Delivery
Author : Yashwant V Pathak
Publisher : Springer
Release Date : 2019-03-11
ISBN 10 : 3030061159
Pages : 499 pages
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This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release Date : 2017-05-03
ISBN 10 : 0323527264
Pages : 372 pages
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Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriented guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment. Explores the benefits of using a variety of nanomaterials as drug delivery agents Explains how nanocarriers can reduce the side effects of therapeutic agents Provides an analysis of the pros and cons of using specific nanocarriers to solve particular diagnosis and delivery problems

Nanotheranostics for Cancer Applications
Author : Prakash Rai,Stephanie A. Morris
Publisher : Springer
Release Date : 2018-11-12
ISBN 10 : 3030017753
Pages : 480 pages
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This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Breast Cancer
Author : Phuc Van Pham
Publisher : BoD – Books on Demand
Release Date : 2017-04-05
ISBN 10 : 9535129996
Pages : 568 pages
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Breast Cancer - From Biology to Medicine thoroughly examines breast cancer from basic definitions, to cellular and molecular biology, to diagnosis and treatment. This book also has some additional focus on preclinical and clinical results in diagnosis and treatment of breast cancer. The book begins with introduction on epidemiology and pathophysiology of breast cancer in Section 1. In Section 2, the subsequent chapters introduce molecular and cellular biology of breast cancer with some particular signaling pathways, the gene expression, as well as the gene methylation and genomic imprinting, especially the existence of breast cancer stem cells. In Section 3, some new diagnostic methods and updated therapies from surgery, chemotherapy, hormone therapy, immunotherapy, radiotherapy, and some complementary therapies are discussed. This book provides a succinct yet comprehensive overview of breast cancer for advanced students, graduate students, and researchers as well as those working with breast cancer in a clinical setting.

Biomimetic Nanoengineered Materials for Advanced Drug Delivery
Author : Afeesh Rajan Unnithan,Arathyram Ramachandra Kurup Sasikala,Cheol Sang Kim,Chan Hee Park
Publisher : N.A
Release Date : 2019-10
ISBN 10 : 9780128149447
Pages : 445 pages
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Biomimetic Nanoengineered Materials for Advanced Drug Delivery is an indispensable guide for new developments in biomimetic nanoengineering for advanced drug delivery applications. Focusing on the fundamentals of a new type of nanocarriers for drug delivery in the most recent miRNA therapeutics, the book provides readers with detailed knowledge from the basics, to the most recent innovations. Early chapters of the book discuss a range of drug delivery techniques, including nanofibers, biomimetic polymers, 3D bioprinting, nanotechnology and radiofrequency sensitive nanocarriers. Later chapters explore miRNA therapeutics, magnetic nanoparticles, nanogel-based and ROS-mediated drug delivery systems. The book is a vital reference for biomaterials and nanomedicine researchers and clinicians with an interest in advanced drug delivery. Analyzes nanoparticle-plasma protein interactions, making it one of the first books on this topic Includes the latest trends in nanotherapeutic drug delivery Presents comprehensive chapters that cover a specific drug delivery carrier and its mode of operation, stimuli and the target site of action Provides an essential tool for researchers in nanomedicine and nanobiomaterials