nanomaterials for clinical applications

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Nanomaterials for Clinical Applications
Author : Costas Demetzos,Natassa Pippa
Publisher : Elsevier
Release Date : 2020-02-14
ISBN 10 : 0128168765
Pages : 322 pages

Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice

Nanomaterials for Medical Applications
Author : Zoraida Aguilar
Publisher : Newnes
Release Date : 2012
ISBN 10 : 0123850894
Pages : 461 pages

This title covers recent advances in a variety of biomedical applications of nanostructured materials, as the field evolves from prototype device to real-world application. It presents the main types of nanomaterial used in medical application today: semiconductor nanomaterials, Magnetic nanomaterials, metal nanoparticles, Carbon nanomaterials, Hydrogel nanocomposites, Liposomes, Dendrimers, Polymer nanocomposites, and Biodegradable polymers. Structurally the work is demarcated into the six most popular areas of research: (1) biocompatibility of nanomaterials with living organisms in their various manifestations (2) nanobiosensors for clinical diagnostics, detecting biomolecules which are useful in the clinical diagnosis of genetic, metabolically acquired, induced or infectious disease (3) targeted drug delivery for nanomaterials in their various modifications (4) nanomedical devices and structures which are used in the development of implantable medical devices and structures such as nanorobots (5) nanopharmacology, as novel nanoparticles are increasingly engineered to diagnose conditions and recognize pathogens, identify ideal pharmaceutical agents to treat the condition or pathogens,fuel high-yield production of matched pharmaceuticals (potentially in vivo), locate, attach or enter target tissue, structures or pathogens; and dispense the ideal mass of matched biological compound to the target regions (6) nanotoxicology and remediation, which focuses on finished and on-going various toxicity evaluations on various nanomaterials that are used and currently being developed for medical applications Discusses the most important biomedical applications and devices of nanomaterials: drug delivery, medical imaging, gene therapy, nanorobots, biosensors and diagnostics Focuses on current commercialized techniques and applications, ensuring the work is entirely relevant to a rapidly evolving field Reviews the most recent studies on nanomaterial toxicity, thereby responding to the widescale private, policy and public interest in nanoscience

Clinical Applications of Magnetic Nanoparticles
Author : Nguyen TK Thanh
Publisher : CRC Press
Release Date : 2018-02-06
ISBN 10 : 1351685422
Pages : 490 pages

Offering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.

Handbook of Clinical Nanomedicine
Author : Raj Bawa,Gerald F. Audette,Israel Rubinstein
Publisher : CRC Press
Release Date : 2016-02-22
ISBN 10 : 9814669210
Pages : 1708 pages

This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosim

Nanoparticles for Biomedical Applications
Author : Eun Ji Chung,Lorraine Leon,Carlos Rinaldi
Publisher : Elsevier
Release Date : 2019-11-19
ISBN 10 : 0128166630
Pages : 440 pages

Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions and Clinical Applications brings into one place information on the design and biomedical applications of different classes of nanoparticles. While aspects are dealt with in individual journal articles, there is not one source that covers this area comprehensively. This book fills this gap in the literature. Outlines an in-depth review of biomedical applications of a variety of nanoparticle classes Discusses the major techniques for designing nanoparticles for use in biomedicine Explores safety and regulatory aspects for the use of nanoparticles in biomedicine

Biomedical Applications of Functionalized Nanomaterials
Author : Bruno Sarmento,Jose Das Neves
Publisher : William Andrew
Release Date : 2018-03-01
ISBN 10 : 0323508790
Pages : 778 pages

Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies. Provides an overview of the methodologies for biological target identification and ligand screening Includes case studies showing the development of functionalized nanomaterials and their biomedical applications Highlights the importance of functionalized nanomaterials for drug delivery, diagnostics and regenerative medicine applications

Nanotechnology for Biomedical Imaging and Diagnostics
Author : Mikhail Y. Berezin
Publisher : John Wiley & Sons
Release Date : 2015-02-02
ISBN 10 : 1118873149
Pages : 520 pages

Nanotechnology for Biomedical Imaging and Diagnostics: FromNanoparticle Design to Clinical Applications reflects upon theincreasing role of nanomaterials in biological and medical imaging,presenting a thorough description of current research as wellas future directions. With contributions from experts innanotechnology and imaging from academia, industry, andhealthcare, this book provides a comprehensive coverage of thefield, ranging from the architectural design of nanomaterials totheir broad imaging applications in medicine. Grouped into three sections, the book: Elucidates all major aspects of nanotechnology andbioimaging Provides comprehensive coverage of the field, ranging from thearchitectural design of nanomaterials to their broad imagingapplications in medicine Written by well-recognized experts in academia, industry, andhealthcare, will be an excellence source of reference With a multidisciplinary approach and a balance of research anddiagnostic topics, this book will appeal to students, scientiests,and healthcare professionals alike

Nanobiomaterials in Clinical Dentistry
Author : Karthikeyan Subramani,Waqar Ahmed
Publisher : Elsevier
Release Date : 2019-04-14
ISBN 10 : 0128158875
Pages : 692 pages

Nanobiomaterials in Clinical Dentistry, Second Edition shows how a variety of nanomaterials are being used to solve problems in clinical dentistry. New nanomaterials are leading to a range of emerging dental treatments that utilize more biomimetic materials that more closely duplicate natural tooth structure (or bone, in the case of implants). The book's chapters discuss the advantages and challenges of using nanomaterials and include case studies to illustrate how a variety of materials are best used in research and practice. Contains information from an interdisciplinary, international group of scientists and practitioners in the fields of nanomaterials, dental implants, medical devices and clinical practice Presents a comprehensive reference on the subject that covers material fabrication and the use of materials for all major diagnostic and therapeutic dental applications--repair, restoration, regeneration, implants and prevention Complements the editors' previous book on nanotechnology applications for dentistry

Nano-inspired Biosensors for Protein Assay with Clinical Applications
Author : Genxi Li
Publisher : Elsevier
Release Date : 2018-08-29
ISBN 10 : 0128150548
Pages : 378 pages

Nano-inspired Biosensors for Protein Assay with Clinical Applications introduces the latest developments in nano-inspired biosensing, helping readers understand both the fundamentals and frontiers in this rapidly advancing field. In recent decades, there has been increased interest in nano-inspired biosensors for clinical application. Proteins, e.g. antigen-antibody, tumor markers and enzymes are the most important target in disease diagnosis, and a variety of biosensing techniques and strategies have been developed for protein assay. This book brings together all the current literature on the most recent advances of protein analysis and new methodologies in designing new kinds of biosensors for clinical diagnostic use. Provides a single source of information on the latest developments in the field of biosensors for protein analysis and clinical diagnosis Focuses on biosensors fabricated with nanomaterials and nanotechnology Gives detailed methodologies for designing and fabricating nano-inspired biosensors

Handbook of Nanomaterials for Industrial Applications
Author : Chaudhery Mustansar Hussain
Publisher : Elsevier
Release Date : 2018-07-19
ISBN 10 : 012813352X
Pages : 1142 pages

Handbook of Nanomaterials for Industrial Applications explores the use of novel nanomaterials in the industrial arena. The book covers nanomaterials and the techniques that can play vital roles in many industrial procedures, such as increasing sensitivity, magnifying precision and improving production limits. In addition, the book stresses that these approaches tend to provide green, sustainable solutions for industrial developments. Finally, the legal, economical and toxicity aspects of nanomaterials are covered in detail, making this is a comprehensive, important resource for anyone wanting to learn more about how nanomaterials are changing the way we create products in modern industry. Demonstrates how cutting-edge developments in nanomaterials translate into real-world innovations in a range of industry sectors Explores how using nanomaterials can help engineers to create innovative consumer products Discusses the legal, economical and toxicity issues arising from the industrial applications of nanomaterials

Carbon Nanomaterials for Biological and Medical Applications
Author : Sekhar Chandra Ray,Nikhil Ranjan Jana
Publisher : Elsevier
Release Date : 2017-03-07
ISBN 10 : 0323479073
Pages : 250 pages

Nanomaterials for Biological and Medical Applications explores the different applications of carbon nanomaterials in drug and gene therapies and their use in tissue regeneration, biosensor diagnosis, enantiomer separation of chiral drugs, extraction and analysis of drugs and pollutants, and as antitoxents. The book describes the synthesis processing of carbon nanomaterials, carbon composite nanomaterials, and their different biological and biomedical applications, including the removal of biologically toxic materials, optical biosensor applications, bio-imaging probe, drug delivery, cancer treatments, and other biomedical applications. Explains the major synthesis chemical process of carbon nanomaterials for biological applications Discusses how carbon nanomaterials can be practically used to create more efficient nanodevices in biosensing, medical imaging, and drug delivery Explores how the unique physical properties of carbon nanomaterials allows them to remove biologically toxic materials

Nanomaterials and Neoplasms
Author : Valerio Voliani
Publisher : CRC Press
Release Date : 2021-01-26
ISBN 10 : 0429650892
Pages : 1282 pages

Nanomaterials have the potential to shift the paradigm for the diagnosis and treatment of many diseases, especially neoplasms, because of the intriguing behaviors associated with their unique size-/shape-influenced chemical, physical, and physiological features. Currently, there is a huge imbalance between the several nanoplatforms reported in the literature and the few ones approved for clinical applications. This disequilibrium affects, in particular, plasmonic nanomaterials, which present no approved platforms and few candidates in clinical trials. This trend can be reversed by promoting collaborations among scientists from different fields as well as by improving the multidisciplinary background of researchers interested in this area. This book is a collection of must-read peer-reviewed papers focusing on (i) the main behaviors of nanomaterials for nanomedicine, (ii) key features nanomaterials need for successful translation to the clinical setting, and (iii) market analysis of nanomaterials at the bedside or on the way. The main aim of this book is to offer a comprehensive point of view to students and researchers in order to promote the translation of new technologies to patients. It is a unique reference for advanced undergraduate- and graduate-level students of nanotechnology and researchers in materials science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in cancer theranostics.

Nanotechnology in Endodontics
Author : Anil Kishen
Publisher : Springer
Release Date : 2015-03-18
ISBN 10 : 3319135759
Pages : 199 pages

This book provides detailed information on the emerging applications of nanomaterials and nanoparticles within endodontics, highlighting the exciting potential clinical impact of nanotechnology in the field. The range of applications covered is diverse, encompassing drug and gene delivery, tissue engineering, antibacterial strategies, dentin tissue stabilization, dentin pulp regeneration and use in restorative and endodontic materials. Important scientific background information relating to each application is provided, with clear coverage of basic principles. In addition, potential pitfalls are identified and explained. The cytotoxicity of nanomaterials and nanoparticles is also addressed in a separate chapter. The book will be of value both for endodontic practitioners and for all scientists and graduate students who are interested in the application of nanotechnology in endodontics.

Biological and Pharmaceutical Applications of Nanomaterials
Author : Polina Prokopovich
Publisher : CRC Press
Release Date : 2015-06-26
ISBN 10 : 1482250179
Pages : 444 pages

Biological and Pharmaceutical Applications of Nanomaterials presents the findings of cutting-edge research activities in the field of nanomaterials, with a particular emphasis on biological and pharmaceutical applications. Divided into four sections—nanomaterials for drug delivery, antimicrobial nanomaterials, nanomaterials in biosensors, and safety of nanomaterials—this book: Covers topics such as stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for targeting drug delivery and dental applications Describes the use of nanocarriers and nanoparticles as cancer and peptide therapeutics, the influence of surface characteristics on microbial adhesion, and the latest developments in antimicrobial nanostructured polymers for medical applications Discusses recent advances in nanodiagnostic techniques for infectious agents, chromogenic biosensors for pathogen detection, electrochemical biosensors for detecting DNA damage and genotoxicity, and molecular imaging with quantum dots including surface modifications by polymers for biosensing applications Featuring contributions from field experts and researchers in industry and academia, Biological and Pharmaceutical Applications of Nanomaterials provides state-of-the-art information on nanomaterials and their use in drug delivery, infection control, and biomedicine.

Polymeric Nanomaterials in Nanotherapeutics
Author : N.A
Publisher : Elsevier
Release Date : 2018-10-26
ISBN 10 : 0128139331
Pages : 558 pages

Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods of administration discussed include oral, dental, topical and transdermal, pulmonary and nasal, ocular, vaginal, and brain drug delivery and targeting. Drug delivery topics treated in several subchapters includes materials for active targeting and cases study of polymeric nanomaterials in clinical trials. The toxicity and regulatory status of therapeutic polymeric nanomaterials are also examined. The book gives a broad perspective on the topic for researchers, postgraduate students and professionals in the biomaterials, biotechnology, and biomedical fields. Shows how the properties of polymeric nanomaterials can be used to create more efficient medical treatments/therapies Demonstrates the potential and range of applications of polymeric nanomaterials in disease prevention, diagnosis, drug development, and for improving treatment outcomes Accurately explains how nanotherapeutics can help in solving problems in the field through the latest technologies and formulations

Nanomaterials for Food Applications
Author : N.A
Publisher : Elsevier
Release Date : 2018-11-16
ISBN 10 : 012814131X
Pages : 444 pages

Nanomaterials for Food Applications highlights recent developments in nanotechnologies, covering the different food areas where these novel products or technologies can be applied. The book covers five major themes, showing how nanotechnology is used in food, the use of ingredients in nanoform to improve bioavailability or nanoencapsulation technologies, nanotechnologies for food processing, nanosensors for food quality and safety, nanotechnologies for food packaging, and methods to evaluate potential risks and regulatory issues. This is an important research reference that will be of great value to academic and industrial readers, as topics of importance, both at a research level and for commercial applications, are covered. Regulatory agencies will also be interested in the latest developments covered in the book as they will help set the foundation for further regulations. Demonstrates how nanotechnology can improve food quality and safety Shows how nanotechnology is used to create more effective food processing techniques Discusses the regulatory issues surrounding the use of nanomaterials in food to ensure they are used safely and responsibly

Medical Nanotechnology and Nanomedicine
Author : Harry F. Tibbals
Publisher : CRC Press
Release Date : 2010-09-29
ISBN 10 : 1439808767
Pages : 527 pages

Considering the fluid nature of nano breakthroughs—and the delicate balance between benefits and consequences as they apply to medicine—readers at all levels require a practical, understandable base of information about these developments to take greatest advantage of them. Medical Nanotechnology and Nanomedicine meets that need by introducing non-experts to nanomedicine and its evolving organizational infrastructure. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects—an ideal foundation upon which to plan and make decisions. Covers the use of nanotechnology in medical applications including imaging, diagnosis and monitoring, drug delivery systems, surgery, tissue regeneration, and prosthetics Part of the Perspectives in Nanotechnology series—which contains broader coverage of the societal implications of nanotechnology—this book can be used as a standalone reference. Organized by historical perspective, current status, and future prospects, this powerful book: Explores background, definitions and terms, and recent trends and forces in nanomedicine Surveys the landscape of nanomedicine in government, academia, and the private sector Reviews projected future directions, capabilities, sustainability, and equity of nanomedicine, and choices to be made regarding its use Includes graphical illustrations, references, and keywords to reinforce concepts and aid further research In its assessment of alternative and sometimes conflicting concepts proposed for the application of nanotechnology to medicine, this book surveys major initiatives and the work of leading labs and innovators. It uses informative examples and case summaries to illustrate proven accomplishments and imagined possibilities in research and development.

Novel Nanomaterials for Biomedical, Environmental and Energy Applications
Author : Xiaoru Wang,Xi Chen
Publisher : Elsevier
Release Date : 2018-11-16
ISBN 10 : 012814498X
Pages : 493 pages

Novel Nanomaterials for Biomedical, Environmental, and Energy Applications is a comprehensive study on the cutting-edge progress in the synthesis and characterization of novel nanomaterials and their subsequent advances and uses in biomedical, environmental and energy applications. Covering novel concepts and key points of interest, this book explores the frontier applications of nanomaterials. Chapters discuss the overall progress of novel nanomaterial applications in the biomedical, environmental and energy fields, introduce the synthesis, characterization, properties and applications of novel nanomaterials, discuss biomedical applications, and cover the electrocatalytical and photothermal effects of novel nanomaterials for efficient energy applications. The book will be invaluable to academic researchers and biomedical clinicians working with nanomaterials. Offers comprehensive details on novel and emerging nanomaterials Presents a comprehensive view of new and emerging tactics for the synthesis of efficient nanomaterials Describes and monitors the functions of applications of new and emerging nanomaterials in the biomedical, environmental and energy fields

Nanomaterials in Diagnostic Tools and Devices
Author : Suvardhan Kanchi,D. Sharma
Publisher : Elsevier
Release Date : 2020-06-04
ISBN 10 : 0128179244
Pages : 618 pages

Nanomaterials in Diagnostic Tools and Devices provides a complete overview of the significance of nanomaterials in fabricating selective and performance enhanced nanodevices. It is an interdisciplinary reference that includes contributing subjects from nanomaterials, biosensors, materials science, biomedical instrumentation and medicinal chemistry. This book is authored by experts in the field of nanomaterial synthesis, modeling, and biosensor applications, and provides insight to readers working in various science fields on the latest advancements in smart and miniaturized nanodevices. These devices enable convenient real-time diagnosis of diseases at clinics rather than laboratories, and include implantable devices that cause less irritation and have improved functionality. Research in the field of nanomaterials is growing rapidly, creating a significant impact across different science disciplines and nanotechnology industries. This synthesis and modeling of nanomaterials has led to many technology breakthroughs and applications, especially in medical science. Provides a distinctive platform for the latest trends in the synthesis of smart nanomaterials for nanodevices in disease diagnostics Presents a broad range of advancements and applications of lateral-flow nanostrip for point-of-care applications Examines smart-phone based nanodevices for field-based diagnosis with accurate information Comprises more than 70 figures and illustrations that will help readers visualize and easily understand the role of nanodevices in the field of nanomedicine Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time and in-situ clinical diagnosis and drug delivery

Emerging Nanotechnologies in Dentistry
Author : Karthikeyan Subramani,Waqar Ahmed
Publisher : William Andrew
Release Date : 2012
ISBN 10 : 1455778621
Pages : 410 pages

Nanotechnology and the future of Dentistry -- Nanoparticles for Dental Materials: Synthesis, analysis and Applications -- Antimicrobial nanoparticles in Restorative Composites -- Nanotechnology in operative dentistry: a perspective approach of history, mechanical behavior and clinical application -- Nanotechnology and dental implants -- Titanium surface modification techniques for dental implants - From microscale to nanoscale -- Titanium nanotubes as carriers of osteogenic growth factors and antibacterial drugs for applications in dental implantology -- Cellular responses to nanoscale surface modifications of titanium implants for dentistry and bone tissue engineering applications -- Corrosion Resistance of Ti6Al4V with Nanostructured TiO2 Coatings -- Multiwalled Carbon Nanotubes/Hydroxyapatite Nanoparticles incorporated GTR membranes -- Fabrication of PEG hydrogel micropatterns by Soft-photolithography and PEG hydrogel as Guided Bone Regeneration membrane in dental implantology -- Na ...