mutagenicity

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Mutagenicity: Assays and Applications
Author : Ashutosh Kumar,Vasily N. Dobrovolsky,Alok Dhawan,Rishi Shanker
Publisher : Academic Press
Release Date : 2017-09-26
ISBN 10 : 0128092602
Pages : 350 pages
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Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with practical and procedural detail, along with their presentation and data processing aspects. It is an essential reference covering the breadth and depth of the field of mutagenicity studies and regulation. By providing both important introductory material and practical assays and applications, this book is useful to graduate students, academic and industry researchers and regulators at various stages of their careers, leading to improved risk assessment and regulation. Presents an up-to-date and in-depth review of the current state of mutagenesis research Draws upon the combined experience and expertise of an international group of highly respected editors and chapter authors Provides an introduction to the concept of mutagenesis with particular consideration given to novel chemicals and materials

Mutagenicity of Puget Sound Sediment Extracts
Author : R. N. Dexter,S. P. Pavlou,Richard M. Kocan
Publisher : N.A
Release Date : 1979
ISBN 10 :
Pages : 27 pages
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Mutagenicity, Carcinogenicity, and Teratogenicity of Industrial Pollutants
Author : Micheline Kirsch-Volders
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
ISBN 10 : 1461326435
Pages : 336 pages
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This book is intended for anyone who cares about the health of people exposed to industrial pollutants. Attention is given to those pollutants which present a possible risk to the genetic material of exposed workers. Chapters are devoted to heavy metals such as arsenic, beryllium, cadmium, chromium, lead, mercury, nickel, etc.; insecticides (chlorinated, organophosphorus, and carbonate insecticides); monomers such as vinyl-chloride, acrylonitrile, styrene, vinylidene chloride, butadiene, chlorobutadiene, hexachlorobuta diene, etc.; and halogenated hydrocarbon solvents such as chloroform, carbon tetrachloride, trichloroethylene, I, 2-dichloroethane, tetrachloroethyl ene, dichloromethane, and I, I, I-trichloroethane. The main aim of this work is to provide the physician, the biologist, the pharmacologist, or anyone involved in genetic toxicology with a useful compendium of up-to-date information and references. Efforts are made to open the field to nonspecialists. An introductory chapter deals with the mechanisms whereby a given compound, reaching genetic material, either directly or indirectly, may increase the risk of a cancer developing in the exposed individual and of abnormalities being passed on to his or her progeny. Efforts are also made to allow easy and efficient reading for those who are not interested in detailed results. Comparative tables provide the following data on the compounds studied: chemical properties, production, occurrence, accepted standards in the industry, and positive or negative results with different test systems. Finally, senior research workers might find good descriptions in this book of the most recent results from mutagenesis and carcinogenesis testing in plant, nonmammalian, and mammalian systems.

Mutagenicity of Alternaria Alternata and A. Tenuis Extracts and Purified Toxins in the Ames Test
Author : Mary Alice Woody
Publisher : N.A
Release Date : 1986
ISBN 10 :
Pages : 504 pages
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Environmental Health Perspectives
Author : N.A
Publisher : N.A
Release Date : 1990
ISBN 10 :
Pages : 329 pages
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Mutagenicity Testing
Author : S. Venitt,J. M. Parry,Jennifer M. Parry
Publisher : Irl Press
Release Date : 1984
ISBN 10 :
Pages : 353 pages
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LABORATORY MANUAL. GENETIC TOXICOLOGY. BACTERIA. YEAST. FRUIT FLY. CULTURED MAMMALIAN CELLS. CYTOGENETIC TESTING. RODENTS. DOMINANT LETHAL TEST.

Handbook of Mutagenicity Test Procedures
Author : B.J. Kilbey,M. Legator,W. Nicholson,C. Ramel
Publisher : Elsevier
Release Date : 2012-12-02
ISBN 10 : 0444600981
Pages : 876 pages
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The compilation of this book was prompted by the necessity of a bench volume which could provide the necessary background information on materials, experimental design, pitfalls and dificulties, in order to perform a particular test in an acceptable way with a minimal need for additional expert help. This Second Edition updates this information, providing: - a comprehensive bench guide - methods known to be reliable - a broad spectrum of approaches - tips to avoid pitfalls when using unfamiliar techniques - data from population records - safety aspects of mutagens and carcinogens - basic statistical concepts for experiment design This `on the bench' methodological text provides the necessary information for most of the common assays for genetic damage in use. The book includes methods which have been sufficiently used and tested to make their use reliable, but also presents methods which are not widely used at present, but which might prove most useful in screening for mutagenic effects.

Use of the Ames Test for Investigating the Mutagenicity of Air Pollutants
Author : Katarina Victorin
Publisher : N.A
Release Date : 1988
ISBN 10 :
Pages : 182 pages
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Guidelines for the Testing of Chemicals for Mutagenicity
Author : Great Britain. Committee on Mutagenicity of Chemicals in Food, Consumer Products, and the Environment,Great Britain. Department of Health
Publisher : N.A
Release Date : 1989
ISBN 10 :
Pages : 98 pages
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Mutagenicity Testing in Environmental Pollution Control
Author : Friedrich K. Zimmermann,R. E. Taylor-Mayer
Publisher : Halsted Press
Release Date : 1985
ISBN 10 :
Pages : 195 pages
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Mutagenicity of Ethylene Oxide and Associated Health Hazard
Author : James Willard Embree
Publisher : N.A
Release Date : 1976
ISBN 10 :
Pages : 138 pages
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