Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis. The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas. Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes Provides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surface Unlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics
|Author||: Ali Khademhosseini|
|Publisher||: Artech House|
|Release Date||: 2008-02-28|
|ISBN 10||: 1596931493|
|Pages||: 627 pages|
Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography.
Fuel cells are clean and efficient energy conversion devices expected to be the next generation power source. During more than 17 decades of research and development, various types of fuel cells have been developed with a view to meet the different energy demands and application requirements. Scientists have devoted a great deal of time and effort
|Release Date||: 2006|
|Pages||: 329 pages|
|Author||: Vuk Uskokovic|
|Release Date||: 2017-11-22|
|ISBN 10||: 0323480640|
|Pages||: 616 pages|
Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments
Combining robotics with nanotechnology, this ready reference summarizes the fundamentals and emerging applications in this fascinating research field. This is the first book to introduce tools specifically designed and made for manipulating micro- and nanometer-sized objects, and presents such examples as semiconductor packaging and clinical diagnostics as well as surgery. The first part discusses various topics of on-chip and device-based micro- and nanomanipulation, including the use of acoustic, magnetic, optical or dielectrophoretic fields, while surface-driven and high-speed microfluidic manipulation for biophysical applications are also covered. In the second part of the book, the main focus is on microrobotic tools. Alongside magnetic micromanipulators, bacteria and untethered, chapters also discuss silicon nano- and integrated optical tweezers. The book closes with a number of chapters on nanomanipulation using AFM and nanocoils under optical and electron microscopes. Exciting images from the tiniest robotic systems at the nano-level are used to illustrate the examples throughout the work. A must-have book for readers with a background ranging from engineering to nanotechnology.
The book outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells. In the following chapters the influence of biological, chemical, mechanical, and physical properties of surfaces in micro and nano-scale on stem cell behavior are discussed including the mechanotransduction. Biomimetic and bioinspired approaches are highlighted for developing microenvironment of several tissues, and surface engineering applications are discussed in tissue engineering, regenerative medicine and different type of biomaterials in various chapters of the book. This book brings together innovative methodologies and strategies adopted in the research and development of Advanced Surfaces in Stem Cell Research. Well-known worldwide researchers deliberate subjects including: Extracellular matrix proteins for stem cell fate The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator Effects of mechanotransduction on stem cell behavior Modulation of stem cells behavior through bioactive surfaces Influence of controlled micro and nanoengineered surfaces on stem cell fate Nanostructured polymeric surfaces for stem cells Laser surface modification techniques and stem cells applications Plasma polymer deposition: a versatile tool for stem cell research Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments Substrates and surfaces for control of pluripotent stem cell fate and function Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering Silk as a natural biopolymer for tissue engineering
|Author||: Murugan Ramalingam,Esmaiel Jabbari,Seeram Ramakrishna,Ali Khademhosseini|
|Publisher||: John Wiley & Sons|
|Release Date||: 2013-05-10|
|ISBN 10||: 111857480X|
|Pages||: 328 pages|
A cutting-edge look at the application of micro andnanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stemcells/tissue engineering has seen an explosion of activity inrecent years. This book provides a much-needed overview of theseexciting developments, covering all aspects of micro andnanotechnologies, from the fundamental principles to the latestresearch to applications in regenerative medicine. Written and edited by the top researchers in the field, Microand Nanotechnologies in Engineering Stem Cells and Tissuesdescribes advances in material systems along with currenttechniques available for cell, tissue, and organ studies. Readerswill gain tremendous insight into the state of the art of stemcells and tissue engineering, and learn how to use the technologyin their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissuegrowth Various engineering approaches for stem cell, vascular tissue,and bone regeneration The design and processing of biocompatible polymers and otherbiomaterials Characterization of the interactions between cells andbiomaterials Unrivaled among books of this kind, Micro andNanotechnologies in Engineering Stem Cells and Tissues is theultimate forward-looking reference for researchers in numerousdisciplines, from engineering and materials science to biomedicine,and for anyone wishing to understand the trends in thistransformative field.
Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline—from biomedical discovery to clinical implementation—aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation. Provides broad coverage in all research areas focused on the applications of nanotechnology in musculoskeletal regeneration Offers useful guidance for physician-scientists with expertise in orthopedics, regenerative medicine, bioengineering, biomaterials, nanoengineering, stem cell biology, and chemistry Serves as a practical reference for many disciplines, including bioengineering, biomaterials, tissue engineering, regenerative medicine, musculoskeletal regenerative medicine, and nanomedicine
self-assembly and responsiveness of cellular systems; the biomineral formation in bacteria, plants, invertebrates, and vertebrates; the multi-layer structure of skin; the organization of tissue fibers; DNA structures with metal-mediated artificial base pairs; and the anisotropic microstructure of jellyfish mesogloea. In this volume, sensor and microfluidic technologies combined with surface patterning are explored for the diagnosis and monitoring of diseases. The high throughput combinatorial testing of biomaterials in regenerative medicine is also covered. The second volume presents nature-oriented studies and developments in the field of electromechanical devices and systems.
|Author||: Nabeel Ahmad,P. Gopinath|
|Release Date||: 2020-03-29|
|ISBN 10||: 0128178310|
|Pages||: 212 pages|
Intelligent Nanomaterials for Drug Delivery Applications discusses intelligent nanomaterials with a particular focus on commercial and premarket tools. The book looks at the applications of intelligent nanomaterials within the field of medicine and discusses their future role. This includes the use of intelligent nanomaterials for drugs used in cardiovascular and cancer treatments and examines the promising market of nanoparticles for biomedical and biosensing applications. This resource will be of great interest to scientists and researchers involved in multiple disciplines, including micro- and nano-engineering, bionanotechnology, biomedical engineering, and nanomedicine, as well as pharmaceutical and biomedical industries. Focuses on applications of intelligent nanomaterials within the field of medicine and discusses their role in the future Discusses intelligent nanomaterials, with a particular focus on commercial and premarket tools Examines the promising market of nanoparticles for biomedical and biosensing applications