interleukins in cancer biology

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Interleukins in Cancer Biology
Author : Arseniy Yuzhalin,Anton Kutikhin
Publisher : Academic Press
Release Date : 2014-06-27
ISBN 10 : 0128013338
Pages : 356 pages

Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and remembering the most important facts. . Summarizes and discusses existing facts on the impact of all known interleukins in occurrence, development, and progression of cancer Categorizes and clarifies all interleukins based on their role in cancer Contains comprehensive and exhaustive information on each molecule

Cytokines: Interleukins and Their Receptors
Author : Razelle Kurzrock,Moshe Talpaz
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
ISBN 10 : 1461312418
Pages : 388 pages

Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and abnormal human development. Today, it is apparent that cytokines orchestrate growth from the early embryonic stage to maturity and are responsible for the normal function of virtually every organ system. Furthermore, virtually all disease states have been associated, at least in part, with cytokine aberrations. In this volume, the editors have brought together internationally known experts in the field of interleukin research to provide a comprehensive review of the biology of the interleukins and their role in both health and illness, while maintaining a balance between the basic science and clinical aspects. Cytokines: Interleukins and their Receptors should be of interest to a wide variety of researchers including clinical hematologists, oncologists, immunologists, in addition to medical and PhD students and researchers with an interest in cytokines.

Tumor Microenvironment
Author : Alexander Birbrair
Publisher : Springer Nature
Release Date :
ISBN 10 : 3030556174
Pages : 329 pages

Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology
Author : Witold Lasek,Radoslaw Zagozdzon
Publisher : Springer
Release Date : 2016-09-23
ISBN 10 : 3319469061
Pages : 75 pages

This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies).

Advances in Cancer Research
Author : N.A
Publisher : Academic Press
Release Date : 2013-06-11
ISBN 10 : 0124072038
Pages : 416 pages

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Oustanding and original reviews Suitable for researchers and students

Growth Factors and their Receptors in Cancer Metastasis
Author : Wen G. Jiang,K. Matsumoto,T. Nakamura
Publisher : Springer Science & Business Media
Release Date : 2006-04-11
ISBN 10 : 0306483998
Pages : 303 pages

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem to The family of growth factors regulate many processes in human disease consists of more than thirty members in and, in particular, tumor development. humans alone (15, 16). They cluster in Our understanding of how two major groups, the group composed of initiated signals are mediated has both the bone morphogenetic proteins increased dramatically in the last fifteen (BMP) and growth and differentiation years. Firstly, the prototype of factors (GDFs), and the group formed by this still constantly growing family, was the Activins, and Nodals. The two identified and cloned (1). Secondly, the groups differ in their use of receptors for family receptors were transmembrane receptors and the identified by expression cloning from subsequent activation of the mammalian tissue culture (2-7). Thirdly, transcriptional mediators (for recent genetic screens in Drosophila reviews see (13, 14, 17)).

Author : Robert Schreiber,Warren J. Leonard
Publisher : Perspectives Cshl
Release Date : 2018
ISBN 10 : 9781621821250
Pages : 350 pages

" Cytokines are small proteins released by cells that regulate the behavior of other cells. They include interferons, interleukins, and tumor necrosis factor and are important regulators of the immune system. This book examines the spectrum of cytokines that are produced and their roles in normal physiology and disease. Topics covered in this essential volume include: - Cytokines and Long Noncoding RNAs - Negative Regulation of Cytokine Signaling in Immunity - Cytokines and metabolism - Cytokines and viral infection"--

Author : N.A
Publisher : Elsevier
Release Date : 2011-08-09
ISBN 10 : 0080466109
Pages : 600 pages

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

The Cytokine Handbook
Author : Angus W. Thomson,Michael T. Lotze
Publisher : Gulf Professional Publishing
Release Date : 2003
ISBN 10 : 9780126896633
Pages : 1396 pages

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features * Covers all main cytokines and chemokines * Written by experts * Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters * Includes major emphasis on clinical applications * Extensively illustrated with tables and figures

Cancer Research
Author : N.A
Publisher : N.A
Release Date : 2006
ISBN 10 :
Pages : 329 pages

Tumor Immunology and Cancer Therapy
Author : R. H. Goldfarb
Publisher : CRC Press
Release Date : 2020-07-25
ISBN 10 : 1000148300
Pages : 344 pages

Based on a Tumor Immunology Symposium held in Pittsburgh, this work provides comprehensive coverage of the most important aspects of tumor immunology. It reveals novel approaches to the immunotherapy of cancer and presents complex issues in an accessible manner.

Cancer Stem Cells
Author : N.A
Publisher : Academic Press
Release Date : 2019-01-26
ISBN 10 : 0128149957
Pages : 267 pages

Cancer Stem Cells, Volume 141 in the Advances in Cancer Research series, presents the latest release in this ongoing, well-regarded serial that provides invaluable information on the exciting and fast-moving field of cancer research. Topics covered in this new release include SIX-EYA-DACH network control of cancer stem cell properties, Dormancy and the cancer cell niche, Clonal hematopoiesis: A hematopoietic stem cell disorder of aging, Stringent assays to study human breast cancer stem cells, Regulation of breast cancer stem cell specification and maintenance by hypoxia-inducible factors, Cancer stem cells in breast and prostate: fact or fiction, and much more. Provides information on cancer research Offers outstanding and original reviews on a range of cancer research topics, with this release focusing on cancer stem cells Serves as an indispensable reference for researchers and students alike