hyphenations of capillary chromatography with mass spectrometry

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Hyphenations of Capillary Chromatography with Mass Spectrometry
Author : Peter Q. Tranchida,Luigi Mondello
Publisher : Elsevier
Release Date : 2019-12-13
ISBN 10 : 012809639X
Pages : 514 pages

Hyphenations of Capillary Chromatography with Mass Spectrometry provides comprehensive coverage of capillary chromatography with mass spectrometry—both single and multidimensional approaches. The book examines nearly all capillary chromatography approaches, combined with a variety of MS forms, giving readers a wide and detailed view on current-day analytical strategies and applications. Of particular focus are novel developments in the field of MS, such as the Orbitrap, HR ToF, ToF MS with variable electron-impact energy, fast MS-MS and APGC technology. Junior scientists conducting research on mono-dimensional chromatography-MS fundamental relationships and experienced analytical chemists working in conventional capillary chromatography and classical multidimensional chromatography will find this an ideal application-based reference on the hyphenations of these domains. Combines mass spectrometry with a range of chromatographic approaches Emphasizes the importance of both capillary chromatography and mass spectrometry methods, thus stimulating separation scientists to fully exploit both analytical dimensions Authored by two of the world’s leading analytical chemists who have a total of more than 40 years of experience in research and instruction

Handbook of Advanced Chromatography /Mass Spectrometry Techniques
Author : Michal Holcapek,Wm. Craig Byrdwell
Publisher : Elsevier
Release Date : 2017-09-07
ISBN 10 : 0128117338
Pages : 520 pages

Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques. Includes UHPLC, HILIC, nano-liquid chromatographic separations, two-dimensional LC-MS (LCxLC), multiple parallel MS, 2D-GC (GCxGC) methodologies for lipids analysis, and more Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research

Handbook of Spectroscopy
Author : G¿nter Gauglitz,David S. Moore
Publisher : John Wiley & Sons
Release Date : 2014-05-05
ISBN 10 : 3527654720
Pages : 1993 pages

This second, thoroughly revised, updated and enlarged edition provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that may be derived from spectra. It also features new chapters on spectroscopy in nano-dimensions, nano-optics, and polymer analysis. Clearly structured into sixteen sections, it covers everything from spectroscopy in nanodimensions to medicinal applications, spanning a wide range of the electromagnetic spectrum and the physical processes involved, from nuclear phenomena to molecular rotation processes. In addition, data tables provide a comparison of different methods in a standardized form, allowing readers to save valuable time in the decision process by avoiding wrong turns, and also help in selecting the instrumentation and performing the experiments. These four volumes are a must-have companion for daily use in every lab.

Capillary Electromigration Separation Methods
Author : Colin F. Poole
Publisher : Elsevier
Release Date : 2018-04-13
ISBN 10 : 0128096144
Pages : 626 pages

Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins. Edited and authored by world-leading capillary electrophoresis experts Presents comprehensive coverage on the subject Includes extensive referencing that facilitates the identification of key research developments Provides more than 50 figures and tables that aid in the retention of key concepts

Capillary Electrochromatography
Author : F. Svec,Z. Deyl
Publisher : Elsevier
Release Date : 2001-03-14
ISBN 10 : 9780080528472
Pages : 448 pages

This book discusses the evolution and uses for capillary electrochromatography as a new dimension to current separation science. With the emergence of this technique the selection of available separation mechanisms increases dramatically. The book also discusses the new horizons in the separation of non-polar compounds which have been opened as a result of CEC. Over ten chapters authors cover a wide variety of topics and provide the reader with necessary theoretical background, description of the instrumentation, modes of operation and methods of detection and an overview of the broad variety of applications of capillary electrochromatography. To view the full contents as a pdf, please click /inca/publications/misc/621924_contents.pdfhere.

Fundamentals of Contemporary Mass Spectrometry
Author : Chhabil Dass
Publisher : John Wiley & Sons
Release Date : 2007-05-11
ISBN 10 : 0470118482
Pages : 512 pages

Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

Technology in Forensic Science
Author : Deepak Rawtani,Chaudhery Mustansar Hussain
Publisher : John Wiley & Sons
Release Date : 2020-08-19
ISBN 10 : 3527827676
Pages : 416 pages

The book "Technology in Forensic Science" provides an integrated approach by reviewing the usage of modern forensic tools as well as the methods for interpretation of the results. Starting with best practices on sample taking, the book then reviews analytical methods such as high-resolution microscopy and chromatography, biometric approaches, and advanced sensor technology as well as emerging technologies such as nanotechnology and taggant technology. It concludes with an outlook to emerging methods such as AI-based approaches to forensic investigations.

Journal of Chromatography
Author : N.A
Publisher : N.A
Release Date : 2003
ISBN 10 :
Pages : 329 pages

Advances in Chemical Bioanalysis
Author : Frank-Michael Matysik
Publisher : Springer
Release Date : 2014-06-03
ISBN 10 : 3319001825
Pages : 264 pages

Expert authors provide critical, in-depth reviews of available methods for retrieving selective information out of complex biological systems. Sensors, probes and devices are present and future tools of medicinal diagnostics, environmental monitoring, food analysis and molecular biology. These are based on fluorescence, electrochemistry and mass spectrometry. Coverage of this volume includes sensor development for the detection of small analytes, monitoring of biomolecular interactions, analysis of cellular function, development of diagnostic tools.

Ultra Performance Liquid Chromatography Mass Spectrometry
Author : Mu Naushad,Mohammad Rizwan Khan
Publisher : CRC Press
Release Date : 2014-03-18
ISBN 10 : 1466591552
Pages : 480 pages

Due to its high sensitivity and selectivity, liquid chromatography–mass spectrometry (LC–MS) is a powerful technique. It is used for various applications, often involving the detection and identification of chemicals in a complex mixture. Ultra Performance Liquid Chromatography Mass Spectrometry: Evaluation and Applications in Food Analysis presents a unique collection of up-to-date UPLC-MS/MS methods for the separation and quantitative determination of components, contaminants, vitamins, and aroma and flavor compounds in a wide variety of foods and food products. The book begins with an overview of the history, principles, and advancement of chromatography. It discusses the use of UHPLC techniques in food metablomics, approaches for analysis of foodborne carcinogens, and details of UPLC-MS techniques used for the separation and determination of capsaicinoids. Chapters describe the analysis of contaminants in food, including pesticides, aflatoxin, perfluorochemicals, and acrylamide, as well as potentially carcinogenic heterocyclic amines in cooked foods. The book covers food analysis for beneficial compounds, such as the determination of folate, vitamin content analysis, applications for avocado metabolite studies, virgin olive oil component analysis, lactose determination in milk, and analysis of minor components of cocoa and phenolic compounds in fruits and vegetables. With contributions by experts in interdisciplinary fields, this reference offers practical information for readers in research and development, production, and routing analysis of foods and food products.

Mass Spectrometry Handbook
Author : Mike S. Lee
Publisher : John Wiley & Sons
Release Date : 2012-04-16
ISBN 10 : 1118180720
Pages : 1368 pages

Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Advances in Clinical Chemistry
Author : N.A
Publisher : Academic Press
Release Date : 2014-11-20
ISBN 10 : 0128024666
Pages : 284 pages

Volume 67 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory. Expertise of international contributors Latest cutting-edge technologies Comprehensive in scope

Capillary Electrophoresis–Mass Spectrometry for Metabolomics
Author : Rawi Ramautar
Publisher : Royal Society of Chemistry
Release Date : 2018-07-13
ISBN 10 : 178801104X
Pages : 283 pages

Capillary electrophoresis–mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In this book, the unique features of CE-MS for metabolomics studies are highlighted including CE separation modes, capillary coatings and practical aspects of CE-MS coupling alongside a comprehensive overview of recent technological developments and applications. CE-MS can be considered a relatively new technique in the field of metabolomics and it is therefore important to inform the scientific community about the possibilities of advanced CE-MS approaches for metabolomics studies. This book outlines the potential of this technique for researchers working in metabolomics, bioanalytics and biomarker analysis.

Sample Preparation in Biological Mass Spectrometry
Author : Alexander R. Ivanov,Alexander V. Lazarev
Publisher : Springer Science & Business Media
Release Date : 2011-06-15
ISBN 10 : 9789400708280
Pages : 1089 pages

The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.

Journal of Capillary Electrophoresis
Author : N.A
Publisher : N.A
Release Date : 2004
ISBN 10 :
Pages : 329 pages

Fast Liquid Chromatography–Mass Spectrometry Methods in Food and Environmental Analysis
Author : Oscar Núñez,Héctor Gallart-Ayala,Claudia P B Martins,Paolo Lucci
Publisher : World Scientific
Release Date : 2015-02-13
ISBN 10 : 1783264950
Pages : 624 pages

There is a growing need for high-throughput separations in food and environmental research that are able to cope with the analysis of a large number of compounds in very complex matrices. Whereas the most common approach for solving many analytical problems has often been high-performance liquid chromatography (HPLC), the recent use of fast or ultra-fast chromatographic methods for environmental and food analysis has increased the overall sample throughput and laboratory efficiency without loss (and even with an improvement) in the resolution obtained by conventional HPLC systems. This book brings together researchers at the top of their field from across the world to discuss and analyze recent advances in fast liquid chromatography–mass spectrometry (LC–MS) methods in food and environmental analysis. First, the most novel approaches to achieve fast and ultra-fast methods as well as the use of alternative and complementary stationary phases are described. Then, recent advances in fast LC–MS methods are addressed, focusing on novel treatment procedures coupled with LC–MS, new ionization sources, high-resolution mass spectrometry, and the problematic confirmation and quantification aspects in mass spectrometry. Finally, relevant LC–MS applications in food and environmental analysis such as the analysis of pesticides, mycotoxins, food packaging contaminants, perfluorinated compounds and polyphenolic compounds are described. The scope of the book is intentionally broad and is aimed at worldwide analytical laboratories working in food and environmental applications as well as researchers in universities worldwide. Contents: Fast Liquid Chromatography Advances:UHPLC Separations Using Sub-2 μm Particle Size Columns (Julie Schappler, Jean-Luc Veuthey and Davy Guillarme)Core-Shell Column Technology in Fast Liquid Chromatography (Oscar Núñez and Héctor Gallart-Ayala)Monolithic Columns in Fast Liquid Chromatography (Takeshi Hara, Oscar Núñez, Tohru Ikegami and Nobuo Tanaka)High-Temperature Liquid Chromatography (Thorsten Teutenberg)Hydrophilic Interaction Liquid Chromatography (HILIC) and Perfluorinated Stationary Phases (Cristina C Jacob, Héctor Gallart-Ayala and Gonçalo Gamboa da Costa)Advances in Fast Liquid Chromatography–Mass Spectrometry Methods:On-Line Sample Pre-Treatment Procedures Applied to LC–MS (Tony Edge and Joseph Herman)Ambient Mass Spectrometry: Food and Environmental Applications (Tiina J Kauppila and Anu Vaikkinen)Liquid Chromatography–High–Resolution Mass Spectrometry in Environmental and Food Analysis (Paolo Lucci and Claudia P B Martins)Liquid Chromatography–Mass Spectrometry: Quantification and Confirmation Aspects (Jaume Aceña, Daniel Rivas, Bozo Zonja, Sandra Pérez and Damià Barceló)Relevant LC–MS Applications in Food and Environmental Analysis:Multiresidue Analysis of Pesticides: LC–MS/MS versus LC–HRMS (Juan V Sancho and María Ibáñez)Food-Packaging Contaminants (Silvia Lacorte, Montse Cortina, Albert Guart and Antonio Borrell)Liquid Chromatography–Mass Spectrometry for the Analysis of Perfluorinated Compounds in Water Samples (Marianna Rusconi, Stefano Polesello and Sara Valsecchi)Determination of Phenolic Compounds in Food Matrices: Application to Characterization and Authentication (Javier Saurina and Sonia Sentellas)Liquid Chromatography–Mass Spectrometric Analysis of Mycotoxins in Food (Veronica M T Lattanzio and Angelo Visconti) Readership: Scientists or students in mass spectrometry, chemists, biologists, and analysts. Keywords:Mass Spectrometry;Fast Liquid Chromatography;Food Analysis;Environmental Analysis

Gas Chromatographic Techniques and Applications
Author : Alan John Handley,E. R. Adlard
Publisher : Taylor & Francis
Release Date : 2001
ISBN 10 : 9780849305146
Pages : 337 pages

This volume provides an overview of the state of the art in gas chromatography with an emphasis on new technologies. The authors-all drawn from respected industrial and academic laboratories-consider developments in gas chromatographic techniques over the last decade. Application areas are addressed within individual chapters.

Analysis of Antioxidant-Rich Phytochemicals
Author : Zhimin Xu,Luke R. Howard
Publisher : John Wiley & Sons
Release Date : 2012-02-03
ISBN 10 : 111822938X
Pages : 408 pages

To quantify antioxidants in natural sources, the application of chromatography techniques with different detectors followed by skillful sample preparation is necessary. Analysis of Antioxidant-Rich Phytochemicals is the first book that specifically covers and summarizes the details of sample preparation procedures and methods developed to identify and quantify various types of natural antioxidants in foods. Focusing on the principle of quantification methods for natural antioxidants, the book reviews and summarizes current methods used in the determination of antioxidant-rich phytochemicals in different sources. Chapter by chapter, the distinguished team of authors describes the various methods used for analysis of the different antioxidant-rich phytochemicals – phenolic acids; carotenoids; anthocyanins; ellagitannins, flavonols and flavones; catechins and procyanidins; flavanones; stilbenes; phytosterols; and tocopherols and tocotrienols. Going beyond extensive reviews of the scientific literature, the expert contributors call on their accumulated experience in sample extraction and analysis to outline procedures, identify potential problems in dealing with different samples, and offer trouble-shooting tips for the analysis. Analysis of Antioxidant-Rich Phytochemicals covers the important food applications and health-promoting functions of the major antioxidant phytochemicals, presents general analysis principles and procedures, and systematically reviews and summarizes the various analytical methods necessary for each type of natural antioxidant in different food sources.

Encyclopedia of Separation Science
Author : Ian D. Wilson,E. R. Adlard,Michael Cooke,C. F. Poole
Publisher : N.A
Release Date : 2000
ISBN 10 :
Pages : 4954 pages

Volume 1 of this resource encyclopedia contains Level 1, which provides a broad overview of the theory of the 12 main categories of separation techniques. Volumes 2-4 (Level 2) expand coverage with detailed theoretical and technical descriptions of particular techniques. The remaining Volumes 5-9 (Level 3) cover applications of these techniques from the micro to the macro, and from the analytical laboratory bench to large-scale industrial processes. The last volume consists mainly of the index.

Liquid Chromatography
Author : Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola
Publisher : Elsevier
Release Date : 2017-06-23
ISBN 10 : 0128093447
Pages : 838 pages

Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making