hematopoietic cell transplantation for malignant conditions

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Hematopoietic Cell Transplantation for Malignant Conditions
Author : Qaiser Bashir,Mehdi Hamadani
Publisher : Elsevier Health Sciences
Release Date : 2019-02-14
ISBN 10 : 0323568033
Pages : 438 pages
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Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy. Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation. Includes practical information on complications, infectious disease, and special populations such as patients with HIV infection. Consolidates today’s available information in this fast-changing area into one convenient resource.

Hematopoietic Cell Transplantation for Malignant Conditions
Author : Qaiser Bashir,Mehdi Hamadani
Publisher : Elsevier Health Sciences
Release Date : 2019-02-14
ISBN 10 : 0323568033
Pages : 438 pages
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Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy. Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation. Includes practical information on complications, infectious disease, and special populations such as patients with HIV infection. Consolidates today’s available information in this fast-changing area into one convenient resource.

Thomas' Hematopoietic Cell Transplantation
Author : Frederick R. Appelbaum,Stephen J. Forman,Robert S. Negrin,Karl G. Blume
Publisher : John Wiley & Sons
Release Date : 2011-09-26
ISBN 10 : 144435745X
Pages : 1752 pages
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This outstanding reference source on bone marrow transplantation has become recognised as the bible in the field. This fourth edition has been fully revised to reflect latest developments, and now features over 500 illustrations, including a colour plate section. The need for this new edition cannot be overstated - more than 13,000 new cases per year of haematopoietic stem cell transplantation have been reported to the International Bone Marrow Transplant Registry The original editor, Donnall Thomas, was a pioneer in stem cell research and won the 1990 Nobel Prize for his discoveries concerning organ and cell transplantation in the treatment of human diseases. The book also now includes a fully searchable CD with PDFs of the entire content.

Stem Cell Transplantation for Hematologic Malignancies
Author : Robert J. Soiffer
Publisher : Springer Science & Business Media
Release Date : 2004-01-29
ISBN 10 : 1592597335
Pages : 486 pages
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A comprehensive survey of the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic GVHD, delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation.

The EBMT Handbook
Author : Enric Carreras,Carlo Dufour,Mohamad Mohty,Nicolaus Kröger
Publisher : Springer
Release Date : 2018-12-12
ISBN 10 : 3030022781
Pages : 702 pages
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This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.

Hematopoietic Stem Cell Transplantation
Author : Jennifer Treleaven,Austin John Barrett
Publisher : Churchill Livingstone
Release Date : 2009
ISBN 10 : 9780443101472
Pages : 555 pages
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A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. Has a practical, accessible approach with free use of algorithms, list tables. Aimed at the whole transplant team - this is an interdisciplinary field. International contributor team with editors in the UK and USA. Illustrated in colour throughout.

Thomas' Hematopoietic Cell Transplantation
Author : Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum
Publisher : John Wiley & Sons
Release Date : 2015-12-14
ISBN 10 : 1118416120
Pages : 1416 pages
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Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

The European Blood and Marrow Transplantation Textbook for Nurses
Author : Michelle Kenyon,Aleksandra Babic
Publisher : Springer
Release Date : 2018-03-14
ISBN 10 : 3319500260
Pages : 311 pages
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This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Haploidentical Transplantation
Author : Stefan O. Ciurea,Rupert Handgretinger
Publisher : Springer
Release Date : 2018-05-03
ISBN 10 : 3319543105
Pages : 337 pages
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In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.

Hematopoietic Stem Cell Transplantation
Author : Michael R. Bishop
Publisher : Springer Science & Business Media
Release Date : 2009-09-25
ISBN 10 : 9780387785806
Pages : 589 pages
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The dogmas of the quiet past are inadequate to the stormy present. The occasion is piled high with difficulty, and we must rise with the occasion. As our case is new, so we must think anew and act anew. Abraham Lincoln, 1862 When I came across this quote, it made me recall my first participation at an international meeting on bone marrow transplantation, at a time when this was the only term that was used to describe the field. During a particular session there was a presentation on the use of peripheral blood as the sole source of stem cells for transplantation, and a member of the audience rose to state that it was medically unethical to consider such treatment, as it certainly could not contain stem cells. Now nearly twenty years later, peripheral blood is the predominant source of stem cells used for hematopoietic stem cell transplantation. In the same period of time there have been several other dogmatic opinions, which permeate all of medicine, that have come and gone in the field of hematopoietic stem cell transplantation, and will continue to do so with advancements from basic and clinical research. It is within this context that the format of this book was devised. Traditionally reviews on specific topics related to hematopoietic stem cell transplantation reflect the views of a single author or a research group.

Stem Cells in Clinical Practice and Tissue Engineering
Author : Rakesh Sharma
Publisher : BoD – Books on Demand
Release Date : 2018-05-02
ISBN 10 : 1789230101
Pages : 352 pages
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Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Hematopoietic Cell Transplantation in Children with Cancer
Author : Franklin O. Smith,Gregory H. Reaman,Judy M. Racadio
Publisher : Springer Science & Business Media
Release Date : 2013-11-26
ISBN 10 : 3642399207
Pages : 358 pages
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This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.

Allogeneic Immunotherapy for Malignant Diseases
Author : John Barrett,Yin-Zhen Jiang
Publisher : CRC Press
Release Date : 2000-01-27
ISBN 10 : 9780824746766
Pages : 408 pages
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This important reference offers a comprehensive review of the graft-versus-leukemia (GVL) or -tumor (GVT) effect following allogeneic stem cell transplantation and lymphocyte transfusion, covering a wide range of topics from alloimmune responses to clinical applications of GVL, and providing the basics to understand the mechanisms of the GVL effect while demonstrating methods that use the GVL effect to cure a greater number of cancer patients. Presents preliminary data supporting the idea that allogeneic cell therapy can be used not only for the treatment of leukemia but also for metastatic solid tumors! Written by over 40 world renowned experts in the field and containing more than 1450 references for in-depth exploration of the subject, Allogeneic Immunotherapy for Malignant Diseases investigates the capacity of the donor-and the host-to destroy residual leukemia cells by allogeneic immune reaction determines how to direct immune reactions against hematopoietic malignancies safely reveals which other malignant conditions may be responsive to allogeneic-mediated graft-versus-tumor reactions covers the mechanisms that contribute to the development of responses to minor histocompatibility complex (mHC) molecules focuses on the biology of effector cells and their role in mediating GVL reactions in chronic myeloid leukemia (CML) summarizes the putative impact of human mHag on the GVL effect in bone marrow transplantation (BMT) addresses the potential and limitations of oncogene-based immunotherapy examines ways to isolate and control the GVL component of allograft immunity discusses efforts to develop specific anti-leukemic T-cell immunotherapy and more! Attributing the curative effect of allogeneic stem cell transplantation to the GVL or GVT effect, Allogeneic Immunotherapy for Malignant Diseases is an indispensable reference for hematologists, clinical oncologists, immunologists and researchers in the fields of tumor immunology and cancer immunotherapy, internists, residents, and medical school students in these disciplines.

Pathogenesis and Therapy of Graft-versus-Host Disease
Author : Brian C. Betts,Xue-Zhong Yu
Publisher : Frontiers Media SA
Release Date : 2019-12-27
ISBN 10 : 2889631745
Pages : 329 pages
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Manual of Pediatric Hematology and Oncology
Author : Philip Lanzkowsky
Publisher : Elsevier
Release Date : 2005-06-06
ISBN 10 : 0080497314
Pages : 856 pages
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Entirely updated to reflect modern thinking and protocols, the Manual of Pediatric Hematology and Oncology provides concise information needed for the day-to-day management of children with pediatric hematologic and oncologic diseases. The clear style allows readers to make an accurate diagnosis and permits him/her to treat patients even if they have not had extensive previous hematologic or oncologic experience. Pertinent advances in molecular genetics, cytogenetics, immunology, transplantation and biochemistry are the result of 40 years of practical experience by the author in the management of patients and incorporates various contributors who have had extensive clinical experience. * Features numerous tables, flow diagrams, protocols, and algorithms for quick access of essential clinical information necessary for the diagnosis and management of these diseases in children * Designed as a concise, easy to use guide for medical students, residents, fellows, pediatric hematologists/oncologists, pediatric nurses and nurse practitioners * Much of the practical information contained in this manual is not found in standard textbooks * Straightforward style without any redundant words or references

Abeloff's Clinical Oncology E-Book
Author : John E. Niederhuber,James O. Armitage,James H Doroshow,Michael B. Kastan,Joel E. Tepper
Publisher : Elsevier Health Sciences
Release Date : 2013-09-12
ISBN 10 : 1455728810
Pages : 2224 pages
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Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

The BMT Data Book
Author : Reinhold Munker,Hillard M. Lazarus,Kerry Atkinson
Publisher : Cambridge University Press
Release Date : 2009-02-26
ISBN 10 : 0521711002
Pages : 528 pages
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An essential guide to the data, outcome studies and complex decision-making processes involved in blood and marrow stem cell transplantation.

Advances in Malignant Hematology
Author : Hussain I. Saba,Ghulam Mufti
Publisher : John Wiley & Sons
Release Date : 2011-02-23
ISBN 10 : 1444394002
Pages : 440 pages
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This comprehensive book captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward haematological malignancies. This recent and ongoing expansion of knowledge on malignant hematology has not previously been utilized to its full capacity due to its diffuse distribution scattered over the internet and research publications. This book is written by experts from the American and European continent, sharing their current thoughts and knowledge on the pathobiology of malignant haematological diseases of the blood, as well as current treatment strategies and future developments in the area of these haematological diseases.

Manual of Clinical Oncology
Author : Dennis Albert Casciato,Mary C. Territo
Publisher : Lippincott Williams & Wilkins
Release Date : 2009
ISBN 10 : 9780781768849
Pages : 794 pages
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Updated for its Sixth Edition, this pocket manual is a practical, accessible, comprehensive guide to the management of patients with cancer. In an outline format designed for rapid reference, the book provides the essential information needed for fast, effective clinical decision-making at the bedside. Coverage begins with principles of cancer management, proceeds through the specific malignancies, and then focuses on the organ-specific complications of cancer, whether due to the disease or its treatments. The unique appendices permit better readability within the chapters by placing frequently referenced, large, complex, and detailed tables at the end of the book. The appendices present cytogenetic nomenclature, toxicity of chemotherapy, critical tumor identifiers, and combination chemotherapy regimens for lymphomas.

Recent Advances in Hematology-3
Author : Manoranjan Mahapatra
Publisher : JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
Release Date : 2011-05-15
ISBN 10 : 9350258137
Pages : 279 pages
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This new edition offers state-of-the-art chapters by distinguished experts in the field of Hematology. The contributors have critically examined and analyzed into perspective some of the contemporary advances and developments and rising torrent of valuable literature of various aspects of hematology. The text is unique in providing the depth and breadth of knowledge in hematology and also a stimulus for further discussion and future research. A multidisciplinary approach with thought provoking articles on exciting topical issues related to hematology contributed by several experts drawn from I.