Neuroscience is, by definition, a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry using electrophysiology and high-resolution optics. A single topic can be studied using techniques from genetics, imaging, biochemistry, or electrophysiology. Therefore, it can be daunting for young scientists or anyone new to neuroscience to learn how to read the primary literature and develop their own experiments. This volume addresses that gap, gathering multidisciplinary knowledge and providing tools for understanding the neuroscience techniques that are essential to the field, and allowing the reader to design experiments in a variety of neuroscience disciplines. Written to provide a "hands-on" approach for graduate students, postdocs, or anyone new to the neurosciences Techniques within one field are compared, allowing readers to select the best techniques for their own work Includes key articles, books, and protocols for additional detailed study Data analysis boxes in each chapter help with data interpretation and offer guidelines on how best to represent results Walk-through boxes guide readers step-by-step through experiments
Neuroscience is by definition a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry. A single topic such as the auditory system can be studied using techniques from genetics, imaging, biochemistry, or electrophysiology. A young scientist must learn how to read the primary literature and then develop their own experiments. This book offers that scientist an overview of mainstream research techniques, provides guidelines on how to choose one technique over another, offers tips on analyzing data, and provides a list of references for additional detailed study. This book can also assist an experienced scientist understand published studies conducted outside their own subfield. *Written by Stanford University graduate students in neuroscience to provide a "hands-on" approach for other neuroscience graduate students *Techniques within one field will be compared so that user can select best technique for their experiment *Chapters include references (key articles, books, protocols) for additional detailed study *Data Analysis boxes in each chapter help with data interpretation and offer guidelines on how best to represent results *"Walk-through" boxes guide students through the experiment step-by-step
Neuroscience is, by definition, a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry using electrophysiology and high-resolution optics. A single topic can be studied using techniques from genetics, imaging, biochemistry, or electrophysiology. Therefore, it can be daunting for young scientists or anyone new to neuroscience to learn how to read the primary literature and develop their own experiments.This volume addresses that gap, gathering multidisciplinary knowledge and providing tools for understanding the neuroscience techniques that are essential to the field, and allowing the reader to design experiments in a variety of neuroscience disciplines.
This fresh, new textbook provides a thorough and student-friendly guide to the different techniques used in cognitive neuroscience. Given the breadth of neuroimaging techniques available today, this text is invaluable, serving as an approachable text for students, researchers, and writers. This text provides the right level of detail for those who wish to understand the basics of neuroimaging and also provides more advanced material in order to learn further about particular techniques. With a conversational, student-friendly writing style, Aaron Newman introduces the key principles of neuroimaging techniques, the relevant theory and the recent changes in the field.
Unique in its coverage of such an extensive range of methods, Neuroscience Methods: A Guide for Advanced Students provides easy-to-understand descriptions of the many different techniques that are currently being used to study the brain at the molecular and cellular levels. This valuable reference text will help rescue undergraduate and postgraduate students from continuing bewilderment at the methods sections of current neuroscience publications. Topics covered include in vivo and in vitro preparations, electrophysiological, histochemical, hybridization and genetic techniques, measurement of cellular ion concentrations, methods of drug application, production of antibodies, expression systems, and neural grafting.
|Author||: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Guidelines for the Use of Animals in Neuroscience and Behavioral Research|
|Publisher||: National Academies Press|
|Release Date||: 2003-08-22|
|ISBN 10||: 9780309167857|
|Pages||: 223 pages|
Expanding on the National Research Councilâ€™s Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animalâ€™s well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
|Author||: Huangui Xiong,Howard E. Gendelman|
|Release Date||: 2013-11-20|
|ISBN 10||: 9781461487937|
|Pages||: 585 pages|
Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a “blueprint” for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
Brain imaging has revolutionised the field of Psychology - once more concerned with IQ tests, reaction times and questionnaires. Most Psychology departments now have access to an MRI scanner - some have even renamed themselves as departments of cognitive neuroscience. Yet brain imaging can be a minefield, whichever discipline you approach it from. If you are a psychologist, you will have been taught how to do behavioural experiments, but may know little neuroanatomy or neurophysiology. If you are a neurologist or psychiatrist, then you may know the neuroanatomy and neurophysiology, but not know how to carry out experiments on mental phenomena. This is a practical guide to brain imaging, showing how it can advance a true neuroscience of human cognition. It is accessible to those starting out in imaging, whilst also informative for those who have already acquired some expertise. At the heart of the book are 6 main chapters, focusing on - the signal, experimental methods, anatomy, functional specialisation, functional systems, and other methods. For students and researchers in psychology and neuroscience, this is the essential companion when embarking on brain imaging studies.
|Author||: Annette M. B. de Groot,Peter Hagoort|
|Publisher||: John Wiley & Sons|
|Release Date||: 2017-10-23|
|ISBN 10||: 1119109841|
|Pages||: 392 pages|
The first comprehensive guide to research methods and technologies in psycholinguistics and the neurobiology of language Bringing together contributions from a distinguished group of researchers and practitioners, editors Annette M. B. de Groot and Peter Hagoort explore the methods and technologies used by researchers of language acquisition, language processing, and communication, including: traditional observational and behavioral methods; computational modelling; corpus linguistics; and virtual reality. The book also examines neurobiological methods, including functional and structural neuroimaging and molecular genetics. Ideal for students engaged in the field, Research Methods in Psycholinguistics and the Neurobiology of Language examines the relative strengths and weaknesses of various methods in relation to competing approaches. It describes the apparatus involved, the nature of the stimuli and data used, and the data collection and analysis techniques for each method. Featuring numerous example studies, along with many full-color illustrations, this indispensable text will help readers gain a clear picture of the practices and tools described. Brings together contributions from distinguished researchers across an array of related disciplines who explain the underlying assumptions and rationales of their research methods Describes the apparatus involved, the nature of the stimuli and data used, and the data collection and analysis techniques for each method Explores the relative strengths and weaknesses of various methods in relation to competing approaches Features numerous real-world examples, along with many full-color illustrations, to help readers gain a clear picture of the practices and tools described
"A unique and important resource, full of critical practical knowledge and technical details made readily accessible." - Tiffany Ito, University of Colorado at Boulder "A comprehensive and engaging guide to EEG methods in social neuroscience; Dickter and Kiefabber offer practical details for conducting EEG research in a social/personality lab, with a broad perspective on how neuroscience can inform psychology. This is a unique and invaluable resource - a must-have for scientists interested in the social brain." - David M. Amodio, New York University Electroencephalography (EEG) has seen a dramatic increase in application as a research tool in the psychological sciences in recent years. This book provides an introduction to the technology and techniques of EEG in the context of social and cognitive neuroscience research that will appeal to investigators (students or researchers) wishing to broaden their research aims to include EEG, and to those already using EEG but wishing to expand their analytic repertoire. It can also serve as a textbook for a postgraduate course or upper-level undergraduate course in any area of behavioural neuroscience. The book provides an introduction to the theory, technology, and techniques of EEG data analysis along with the practical skills required to engage this popular technology. Beginning with a background in the neural origins and physical principles involved in recording EEG, readers will also find discussions of practical considerations regarding the recording of EEG in humans as well as tips for the configuration of an EEG laboratory. The analytic methods covered include event-related brain potentials (ERPs), spectral asymmetry, and time-frequency analyses. A conceptual background and review of domain-specific applications of the method is provided for each type of analysis. There's also comprehensive guided analysis for each analytic method that includes tutorial-style instruction and sample datasets. This book is perfect for advanced students and researchers in the psychological sciences and related disciplines who are using EEG in their research.
With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates. The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More concise and manageable than the previous edition, this book has been retooled to better serve its audience in the neuroscience and medical communities. Key Features * Logically organized into 7 sections, with uniform editing of the content for a "one-voice" feel throughout all 54 chapters * Includes numerous text boxes with concise, detailed descriptions of specific experiments, disorders, methodological approaches, and concepts * Well-illustrated with over 850 full color figures, also included on the accompanying CD-ROM
Since the first implant of a carbon microelectrode in a rat 35 years ago, there have been substantial advances in the sensitivity, selectivity and temporal resolution of electrochemical techniques. Today, these methods provide neurochemical information that is not accessible by other means. The growing recognition of the versatility of electrochemical techniques indicates a need for a greater understanding of the scientific foundation and use of these powerful tools. Electrochemical Methods for Neuroscience provides an updated summary of the current, albeit evolving, state of the art and lays the scientific foundation for incorporating electrochemical techniques into on-going or newly emerging research programs in the neuroscience disciplines. With contributions from pioneers in the field, the text outlines the applications and benefits of a wide range of electrochemical techniques. It explores the methodology behind the acquisition of neurochemical and neurobiological data through continuous amperometry, fast scan cyclic voltammetry, high-speed chronoamperometry, ion-selective microelectrodes, enzyme based microelectrodes, and in vivo voltammetry with telemetry. The text also introduces emerging concepts in the field such as the correlation of electrochemical recordings with information obtained from patch clamp, electrophysiological, and behavioral techniques. By presenting up-to-date information on the growing collection of electrochemical methods, microsensors, and research techniques, Electrochemical Methods for Neuroscience assists seasoned researchers and newcomers to the field in making sound decisions about adopting the most appropriate of these tools for their future research objectives.