gastrointestinal diseases and their associated infections

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Gastrointestinal Diseases and Their Associated Infections
Author : Guy D. Eslick
Publisher : Elsevier Health Sciences
Release Date : 2019-01-17
ISBN 10 : 032354844X
Pages : 400 pages
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Many bacteria, viruses, protozoa, and fungi play key roles in the development of gastrointestinal diseases, and this practical reference brings you up to speed with this increasingly important area. Covering a broad range of GI diseases and cancers, this resource provides an expert overview of the field, ideal for all gastroenterologists and infectious disease physicians. Covers infections associated with gastroesophageal reflux disease and Barrett’s esophagus, gallbladder disease, acute pancreatitis, small intestinal bacterial overgrowth, irritable bowel syndrome, inflammatory bowel disease, appendicitis, Whipple Disease, Crohn’s Disease, and more. Discusses esophageal cancer, gastric cancer, cholangiocarcinoma, hepatocellular carcinoma, and colorectal cancer. Includes chapters on gut microbiome, fecal transplants, and the molecular pathgenesis of gastrointestinal infections. Consolidates today’s available information on this timely topic into a single convenient resource.

Dietary Interventions in Gastrointestinal Diseases
Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Release Date : 2019-01-10
ISBN 10 : 0128144696
Pages : 358 pages
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Dietary Interventions in Gastrointestinal Diseases: Foods, Nutrients and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the gastrointestinal system. It provides nutritional treatment options for those suffering from gastrointestinal diseases including Crohn’s Disease, Inflammatory Bowel Disease, Ulcerative Colitis and Allergies, among others. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus showing that changes in intake can change antioxidant and disease preventing non-nutrients and affect gastrointestinal health and/or disease promotion. This book serves as a valuable resource for biomedical researchers who focus on identifying the causes of gastrointestinal diseases and food scientists targeting health-related product development. Provides information on agents that affect metabolism and other health-related conditions in the gastrointestinal tract Explores the impact of composition, including differences based on country of origin and processing techniques to highlight compositional differences and their effect on the gastrointestinal tract Addresses the most positive results from dietary interventions using bioactive foods to impact gastrointestinal diseases, including reduction of inflammation and improved function of organs

Diseases of the Gastrointestinal Tract and Associated Infections
Author : Connor Dyer
Publisher : N.A
Release Date : 2018
ISBN 10 : 9781684691777
Pages : 329 pages
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Infections of the Gastrointestinal Tract
Author : Martin J. Blaser,Phillip D. Smith,Jonathan I. Ravdin, M.D.,Harry B. Greenberg
Publisher : N.A
Release Date : 2002
ISBN 10 :
Pages : 1319 pages
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This updated second edition examines the gastrointestinal tract in relation to both immunocompetent and immunocompromised hosts. Written by specialists in infectious diseases and gastroenterology, this edition features discussion on the many infections of the gastrointestinal tract faced by adult and pediatric populations. The text traces the historical and epidemiological aspects of these disorders and provides detailed discussions on diagnosis, treatment, prevention and control, and should be of interest to the infectious disease specialist, gastroenterologist, primary care provider, internist, paediatrician and surgeon.

Hunter's Tropical Medicine and Emerging Infectious Diseases E-Book
Author : Edward T Ryan,David R Hill,Tom Solomon,Timothy P Endy,Naomi Aronson
Publisher : Elsevier Health Sciences
Release Date : 2019-03-25
ISBN 10 : 0323625509
Pages : 1264 pages
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New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules ... all significant, recent developments in the fast-changing field of tropical medicine. Hunter’s Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You’ll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control. Includes important updates on malaria, leishmaniasis, tuberculosis and HIV, as well as coverage of Ebola, Zika virus, Chikungunya, and other emerging pathogens. Provides new vaccine schedules and information on implementation. Features five all-new chapters: Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration; Health System and Health Care Delivery; Zika; Medical Entomology; and Vector Control – as well as 250 new images throughout. Presents the common characteristics and methods of transmission for each tropical disease, as well as the applicable diagnosis, treatment, control, and disease prevention techniques. Contains skills-based chapters such as dentistry, neonatal pediatrics and ICMI, and surgery in the tropics, and service-based chapters such as transfusion in resource-poor settings, microbiology, and imaging. Discusses maladies such as delusional parasitosis that are often seen in returning travelers, including those making international adoptions, transplant patients, medical tourists, and more.

Infections of the Gastrointestinal System
Author : Chetana Vaishnavi
Publisher : JP Medical Ltd
Release Date : 2013-03-31
ISBN 10 : 9350903520
Pages : 644 pages
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Infections of the gastrointestinal (GI) system can be caused by many organisms, including bacteria, parasites, viruses and funghi. This manual is a practical guide providing gastroenterologists and infectious disease specialists with up to date knowledge on GI infections. Beginning with general topics including etiology and prevention, imaging and dietary management, the following chapters present different micro-organisms and the infections and diseases they may cause. The agents responsible for infection, diagnosis, clinical features and therapy for each syndrome are discussed in detail. This comprehensive text includes more than 300 full colour illustrations, slides and photographs, and contributions from experts in microbiology, pathology, histopathology and gastroenterology. Key points Practical guide to gastrointestinal infections Discusses many different micro-organisms and resulting infections and diseases Includes more than 300 illustrations, slides and photographs Contributions from experts in microbiology, pathology, histopathology and gastroenterology

Microbiology
Author : Nina Parker,OpenStax,Mark Schneegurt,AnhHue Thi Tu,Brian M. Forster,Philip Lister
Publisher : N.A
Release Date : 2016-05-30
ISBN 10 : 9781938168147
Pages : 1301 pages
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"Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs. Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology."--BC Campus website.

Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease
Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Release Date : 2012-10-22
ISBN 10 : 0123977649
Pages : 802 pages
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Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related gastrointestinal disease including Crohn’s, allergies, and colitis among others. Information is presented on a variety of foods including herbs, fruits, soy and olive oil. This book serves as a valuable resource for researchers in nutrition, nephrology, and gastroenterology. Addresses the most positive results from dietary interventions using bioactive foods to impact diseases of the liver and gastrointestinal system, including reduction of inflammation, improved function, and nutritional efficiency Presents a wide range of liver and gastrointestinal diseases and provides important information for additional research Associated information can be used to understand other diseases, which share common etiological pathways

Surgical Pathology of Non-neoplastic Gastrointestinal Diseases
Author : Lizhi Zhang,Vishal S. Chandan,Tsung-Teh Wu
Publisher : Springer
Release Date : 2019-06-24
ISBN 10 : 3030155730
Pages : 572 pages
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This book covers the entire spectrum of non-neoplastic diseases within the gastrointestinal (GI) tract including new entities, recent developments, and questions that arise in the practice of GI pathology. The text is organized by specific organ site, with related disorders of each organ site subgrouped into several chapters based on their common features. Pathologists can quickly find the disorders they are interested and review similar disorders in the same chapter to help them make a correct diagnosis. Each major and common entity is described in detail with its definition, clinical features, pathological features (covering both the gross and microscopic details), differential diagnosis and treatment/prognosis. All chapters also highlight the use of special/immunohistochemical stains and other supporting studies as needed with a focus on providing a practical differential diagnosis rather than just a list of potential associations. This book is extensively illustrated with both gross and microscopic images that act as an integral part of the information provided in the text. Written by practicing GI/liver pathologists and gastroenterologists from the Mayo Clinic, Surgical Pathology of Non-neoplastic Gastrointestinal Diseases serves as a comprehensive yet practical guide for diagnostic surgical pathologists with a passion for GI pathology.

Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas
Author : Robert D. Odze,John R. Goldblum
Publisher : Elsevier Health Sciences
Release Date : 2009
ISBN 10 : 1416040595
Pages : 1368 pages
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This one-of-a-kind reference provides a comprehensive and practical guide to help you interpret endoscopic biopsies and resection specimens of all organs related to the digestive system. Plus, thanks to Expert Consult, you'll be able to access the entire contents of this title online and download all images, from anywhere there's an internet connection. The more than 2250 high quality illustrations, 30% more than in the first edition, help you recognize and diagnose any tissue sample under the microscope. Five new chapters, additional expert authors, expanded tables, and coverage of the current clinical approach to management and treatment options, particularly screening and surveillance recommendations for preneoplastic disorders, round out this unique reference. Acts as a one-stop resource for the entire gastrointestinal system, liver, biliary tract, and pancreas. Incorporates over 2250 high quality color illustrations so you can recognize and diagnose any tissue sample under the microscope. Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. Simplifies complex topics and streamlines decision-making using extensive tables, graphs, and flowcharts. Helps you avoid diagnostic errors thanks to practical advice on pitfalls in differential diagnosis. Uses a new "road map" at the beginning of each chapter, as well as a new, more clinical focus to help you navigate through the book more quickly. Reflects the latest classification and staging systems available so you can provide the clinician with the most accurate and up-to-date diagnostic and prognostic indicators, including key molecular aspects of tumor pathology. Includes access to the entire contents online, from anywhere there's an internet connection. Adds five new chapters including "Screening and Surveillance of the GI Tract", "Congenital and Developmental Disorders of the GI Tract", "Pediatric Enteropathies of the GI Tract", "Vascular Disorders of the GI Tract", and "Fatty Liver Disease". Expands appropriate chapters with new coverage of the normal histology of the GI tract, liver, biliary tract and pancreas. Uses expanded tables to outline specific differential diagnostic points helpful for surgical pathologists. Discusses the key molecular aspects of tumor progression and risk assessment in all chapters that cover neoplastic disorders. Helps you evaluate diagnostically challenging cases using diagnostic algorithms. Increases the number of high quality photographs by at least 30% to include even more normal and abnormal tissue samples. Updates all chapters to include the latest references, concepts, data, and controversies. Incorporates expanded coverage of the pancreas and liver, eliminating the need for a separate text. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Blackwell's Five-Minute Veterinary Consult Clinical Companion
Author : Jocelyn Mott,Jo Ann Morrison
Publisher : John Wiley & Sons
Release Date : 2019-07-18
ISBN 10 : 1119376343
Pages : 1000 pages
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Blackwell's Five-Minute Veterinary Consult Clinical Companion: Small Animal Gastrointestinal Diseases offers a highly accessible resource for the most common and not-so common diseases of the gastrointestinal system, pancreas, liver, and gallbladder in small animals. Covers diseases and disorders of the oral cavity and salivary glands, esophagus, stomach, small intestine, colon, anus and perianal region, pancreas, liver, and gall bladder Provides a comprehensive yet concise reference to gastrointestinal and hepatologic diseases encountered in daily veterinary practice Presents the most important information for each disease in a highly accessible format Depicts the clinical conditions discussed with helpful color photographs

Pathology of Infectious Diseases E-Book
Author : Gary W. Procop,Bobbi Pritt
Publisher : Elsevier Health Sciences
Release Date : 2014-07-21
ISBN 10 : 145575384X
Pages : 544 pages
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Pathology of Infectious Diseases, by Gary W. Procop, MD, A Volume in the Foundations in Diagnostic Pathology Series, packs all of today's most essential information on infectious disease pathology into a compact, high-yield format! Well-organized and segmented by type of infectious organism, the book's pragmatic approach complemented by abundant full-color, high-quality photomicrographs and clinical photos, and at-a-glance tables makes it easy to access the information you need to quickly and accurately detect and identify pathogenic organisms. Chapters on immunohistochemical and molecular techniques as well as artifacts and pitfalls guide you to accurate detection and identifications. Quickly find the information you need thanks to a well-organized, user-friendly format with templated headings, detailed illustrations, at-a-glance tables, and segmentation by type of infectious organism—viral, bacterial, fungal, and parasitic. Avoid common problems that can lead to an incorrect diagnosis. A special section on artifacts and pitfalls shows you what to look for. Get superb visual guidance from an abundance of full-color, high-quality photomicrographs and clinical photos. Employ the latest diagnostic advancements including immunohistochemical and molecular techniques. Learn from one of the very best. Dr. Gary W. Procop, one of the most outstanding young clinical pathologists in medical microbiology in American medicine, shares his vision about how new technologies may be used to rapidly identify pathogenic organisms and detect resistance to treatment regimens. Recognized for distinguished research contributions to the discipline of clinical microbiology, he was the recipient of the 2007 American Society for Microbiology (ASM) BD Award for Research in Clinical Microbiology and elected to the American Academy of Microbiology in recognition of his scientific achievements. Implement proven diagnostic approaches such as real-time PCR assays and pepticnucleic acid probes with guidance from the pioneer of these techniques!

Issues in Infectious and Vector-Borne Diseases: 2011 Edition
Author : N.A
Publisher : ScholarlyEditions
Release Date : 2012-01-09
ISBN 10 : 1464965943
Pages : 648 pages
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Issues in Infectious and Vector-Borne Diseases: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Infectious and Vector-Borne Diseases. The editors have built Issues in Infectious and Vector-Borne Diseases: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Infectious and Vector-Borne Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Infectious and Vector-Borne Diseases: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Surgical Pathology of the Gastrointestinal System: Bacterial, Fungal, Viral, and Parasitic Infections
Author : Laura W. Lamps
Publisher : Springer Science & Business Media
Release Date : 2010-03-24
ISBN 10 : 1441908617
Pages : 224 pages
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Surgical Pathology of the Gastrointestinal System: Bacterial, Fungal, Viral, and Parasitic Infections provides a unique diagnostic reference text for the pathologic diagnosis of infectious diseases of the gastrointestinal tract. Written for the practicing surgical pathologist, this text combines the superior illustrations of an atlas with carefully written prose to create a useful diagnostic companion. The text is divided into four sections covering bacterial, fungal, viral, and parasitic infections of the gastrointestinal tract. The descriptive sections of each chapter are organized into short paragraphs for easy reference and include the use of tables to compare and contrast organisms and summarize differential diagnoses. Each chapter is extensively illustrated, and contains prose discussions of diagnostic features, differential diagnoses, brief clinical descriptions, and ancillary tests that help confirm the diagnosis (i.e. immunohistochemistry, special histochemical stains, and molecular diagnostic techniques). Surgical Pathology of the Gastrointestinal System: Bacterial, Fungal, Viral, and Parasitic Infections provides pertinent clinical, diagnostic, and epidemiologic information that will be valuable to the practicing surgical pathologist. This volume will also help surgical pathologists gain familiarity with other contributory laboratory tests that are available to help confirm diagnosis.

Clinical Update on Inflammatory Disorders of the Gastrointestinal Tract
Author : Julia Mayerle,Herbert Tilg
Publisher : Karger Medical and Scientific Publishers
Release Date : 2010
ISBN 10 : 3805592949
Pages : 216 pages
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Digestive-disease-associated mortality accounts for a major part of all deaths in Western societies and inflammatory diseases such as GI infections, viral hepatitis, GERD or cancers due to chronic inflammation have a tangible economic and social impact. What further aggravates the situation is the fact that complex immunological disorders have surfaced where anti-infective treatments are not effective. Fortunately, due to breakthroughs in basic research that are being successfully translated into clinical practice, new treatment strategies are constantly evolving. In addition to the development of new therapeutic measures, however, it is also mandatory to review and periodically refine established treatment regimens to reflect current knowledge and ensure up-to-date medical care.Combining outstanding basic research reviews with cutting-edge treatment guidelines on inflammatory disorders of the GI tract, this book presents newly identified treatment targets and provides clinicians and practitioners in the field with a most useful account of the state of the art.

Biofilms in Human Diseases: Treatment and Control
Author : Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma
Publisher : Springer Nature
Release Date : 2019-11-19
ISBN 10 : 3030307573
Pages : 311 pages
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This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Digestive Diseases in the United States
Author : James E. Everhart
Publisher : DIANE Publishing
Release Date : 1994
ISBN 10 : 0788126040
Pages : 799 pages
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A compendium of descriptive statistics on digestive diseases in the U.S. Each chapter provides analyses of primary data from recent, large U.S. surveys as well as interpretative review of the known epidemiology of each disease or condition. Covers: infectious diarrheas; viral hepatitis; esophageal, colorectal, liver & pancreatic cancer; hemorrhoids; peptic ulcer; constipation; gallstones; inflammatory bowel diseases; pancreatitis; & many more. Also discusses cost of digestive diseases in the U.S.; ICD-9-CM & ICD-10 Digestive Disease Codes.

The Microbiota in Gastrointestinal Pathophysiology
Author : Martin H. Floch,Yehuda Ringel,W. Allen Walker
Publisher : Academic Press
Release Date : 2016-11-16
ISBN 10 : 0128040629
Pages : 442 pages
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The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects Explores the gut microbiota as a therapeutic target Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field Serves as a ‘one-stop’ shop for a topic that’s currently spread across a number of various journals

Gastrointestinal Tissue
Author : Jordi Gracia-Sancho,M. Josepa Salvadó
Publisher : Academic Press
Release Date : 2017-05-10
ISBN 10 : 0128093005
Pages : 394 pages
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Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants brings together leading experts from world renowned institutions, combining the basic mechanisms of gastrointestinal diseases with information regarding new and alternative treatments. The processes within the science of oxidative stress are described in concert with other processes, including apoptosis, cell signaling and receptor mediated responses, further recognizing that diseases are often multifactorial with oxidative stress as a component. By combining the critical molecular processes underlying free radical mediated pathologies and the role of dietary antioxidant molecules, a connection is made that helps advance therapies and the prevention of gastrointestinal pathological processes. This important reference is well designed with two complementary sections. Section One, Oxidative Stress and Gastroenterology, covers the basic processes of oxidative stress from molecular biology to whole organs, the gastrointestinal anatomy and sources of oxidative stress and free radicals and their products in gastrointestinal diseases. Section Two, Antioxidants and Gastroenterology covers antioxidants in foods, including plants and components. Covers the science of oxidative stress in gastrointestinal tissue and associated conditions and scenarios Provides information on optimal levels for human consumption of antioxidants, suggested requirements per day, recommended dietary allowances and curative/preventive effects of dietary antioxidants Presents an easy to reference guide with two complementary sections that discuss the pathophysiology of gastrointestinal diseases in relation to oxidative stress and antioxidant therapies

Healthcare-Associated Infections in Children
Author : J. Chase McNeil,Judith R. Campbell,Jonathan D. Crews
Publisher : Springer
Release Date : 2018-11-08
ISBN 10 : 9783319981215
Pages : 351 pages
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With advances in technology and medical science, children with previously untreatable and often fatal conditions, such as congenital heart disease, extreme prematurity and pediatric malignancy, are living longer. While this is a tremendous achievement, pediatric providers are now more commonly facing challenges in these medical complex children both as a consequence of their underlying disease and the delivery of medical care. The term healthcare-associated infections (HAIs) encompass both infections that occur in the hospital and those that occur as a consequence of healthcare exposure and medical complexity in the outpatient setting. HAIs are associated with substantial morbidity and mortality for the individual patient as well as seriously taxing the healthcare system as a whole. In studies from the early 2000s, over 11% of all children in pediatric intensive care units develop HAIs and this figure increases substantially if neonatal intensive care units are considered. While progress has been made in decreasing the rates of HAI in the hospital, these infections remain a major burden on the medical system. In a study published in 2013, the annual estimated costs of the five most common HAIs in the United States totaled $9.8 billion. An estimated 648,000 patients developed HAIs in hospitals within the US in 2011 and children with healthcare-associated bloodstream infection have a greater than three-fold increased risk of death. While a number of texts discuss HAIs in the broader context of infectious diseases or pediatric infectious diseases (such as Mandell’s Principles and Practice of Infectious Diseases or Long and Pickering’s Principles and Practice of Pediatric Infectious Diseases) no single text specifically focuses on the epidemiology, diagnosis and management of HAI in children. Many infectious diseases texts are organized based on the microbiology of infection and from this starting point then discussing the clinical syndromes associated with the organism of interest. For instance, a chapter on Staphylococcus aureus may contain a brief discussion of the role of S. aureus in surgical site infections in the wider context of all staphylococcal disease. For clinicians caring for children at the bedside, however, the clinical syndrome is typically appreciated and intervention necessary prior to organism identification. We propose a text that details both the general principles involved in HAIs and infection prevention but also provides a problem oriented approach. Such a text would be of interest to intensivists, neonatologists, hospitalists, oncologists, infection preventionists and infectious diseases specialists. The proposed text will be divided into three principle sections: 1) Basic Principles of Infection Control and Prevention, 2) Major Infectious Syndromes and 3) Infections in Vulnerable Hosts. Chapters in the Major Infectious Syndromes section will include discussion of the epidemiology, microbiology, clinical features, diagnosis, medical management (or surgical management as appropriate) and prevention of the disease entity of interest. Chapters will seek to be evidenced based as much as possible drawing from the published medical literature as well as from clinical practice guidelines (such as those from the Infectious Diseases Society of America) when applicable. We intend to include tables, figures and algorithms as appropriate to assist clinicians in the evaluation and management of these often complex patients. Finally, we intend to invite authors to participate in this project from across a number of medical specialties including infectious diseases, infection control, critical care, oncology and surgery to provide a multidisciplinary understanding of disease. It is our intent to have many chapters be co-written by individuals in different subspecialties; for instance, a chapter on ventilator-associated pneumonia may be co-written by both infectious disease and critical care medicine specialists. Such a unique text has the potential to provide important guidance for clinicians caring for these often fragile children.