from pasteur to post genomic era

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Index Medicus
Author : N.A
Publisher : N.A
Release Date : 2004
ISBN 10 :
Pages : 329 pages
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Neurosciences at the Postgenomic Era
Author : Jacques Mallet
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
ISBN 10 : 3642555438
Pages : 189 pages
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In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.

RTD Info
Author : N.A
Publisher : N.A
Release Date : 2002-11
ISBN 10 :
Pages : 329 pages
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Spirochete Biology: The Post Genomic Era
Author : Ben Adler
Publisher : Springer
Release Date : 2018-08-21
ISBN 10 : 3319896385
Pages : 295 pages
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Spirochetes comprise a fascinating group of bacteria. Although diverse in terms of their habitat, ecology and infectivity for vertebrate and non-vertebrate hosts, they are often considered together because of their similar cellular morphologies. This volume brings together an international group of experts to provide essential insights into spirochete biology, with an emphasis on recent advances made possible by the availability of genome sequences. As such, it offers a valuable resource for microbiologists and other scientists with an interest in spirochete biology.

Metabolic Engineering in the Post Genomic Era
Author : Boris N. Kholodenko,Hans V. Westerhoff
Publisher : Garland Science
Release Date : 2004
ISBN 10 : 9780954523220
Pages : 456 pages
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The Horizon Scientific Press titles focus on high-level microbiology and molecular biology topics. Written by internationally renowned and highly respected leaders in the field, titles in this series comprise of review manuals, practical manuals, and reference texts for research scientists, bioscience professionals and graduate students. Engineering living cells continues to pose immense challenges to the researcher. In fact many bioengineers have only just started to appreciate the full extent of the hierarchical control used by living systems: upon attempts to increase the activity of a "rate-limiting" step, the multiple feedbacks at the metabolic, signaling and genetic levels result in the rate limiting step shifting to elsewhere in that pathway or even to elsewhere in the whole organism. The advent of full-force genomics should enable preventing this response, however, it has been difficult for researchers to know where to turn for guidance. This book aims to help the reader understand and deal with the plasticity of living cell factories and to turn the plasticity into the desired rather than the adverse direction. The book brings together all the recent, most important breakthroughs in this exciting field: Internationally renowned key scientists have reviewed each topic in detail. In the Introduction, the editors give an overview of new approaches and spell out what the engineer and the industry may now really begin to aim for; they even adapt the definition of metabolic engineering to befit the post-genomics era. Other topics included are: the experimental approaches necessary to understand cellular regulation at all of its hierarchical levels, including proteomics [Chapter 2], metabolomics [Chapter 3] and fluxomics [Chapter 4]; new tools that help metabolic engineering [Chapters 5-7]; modeling of living cells, e.g. finding metabolic pathways [Chapter 8] and comparing the actual and predicted use of these in living organisms such as E. coli and Corynebacteria [Chapters 9, 10]; the optimization of cell factories as production organisms (e.g., use of whole cell models, silicon cells, and coordinate manipulation of multiple genes [Chapters 12-15]). A chapter on future perspectives directs further developments of the field in the near future. Metabolic Engineering in the Post Genomic Erais an essential reading for everyone with an interest in engineering living cells including: Metabolic egnineers, bioengineers, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.

ASM News
Author : American Society for Microbiology
Publisher : N.A
Release Date : 1999
ISBN 10 :
Pages : 329 pages
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The Science and Applications of Microbial Genomics
Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Release Date : 2013-05-02
ISBN 10 : 0309268192
Pages : 428 pages
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Over the past several decades, new scientific tools and approaches for detecting microbial species have dramatically enhanced our appreciation of the diversity and abundance of the microbiota and its dynamic interactions with the environments within which these microorganisms reside. The first bacterial genome was sequenced in 1995 and took more than 13 months of work to complete. Today, a microorganism's entire genome can be sequenced in a few days. Much as our view of the cosmos was forever altered in the 17th century with the invention of the telescope, these genomic technologies, and the observations derived from them, have fundamentally transformed our appreciation of the microbial world around us. On June 12 and 13, 2012, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to discuss the scientific tools and approaches being used for detecting and characterizing microbial species, and the roles of microbial genomics and metagenomics to better understand the culturable and unculturable microbial world around us. Through invited presentations and discussions, participants examined the use of microbial genomics to explore the diversity, evolution, and adaptation of microorganisms in a wide variety of environments; the molecular mechanisms of disease emergence and epidemiology; and the ways that genomic technologies are being applied to disease outbreak trace back and microbial surveillance. Points that were emphasized by many participants included the need to develop robust standardized sampling protocols, the importance of having the appropriate metadata, data analysis and data management challenges, and information sharing in real time. The Science and Applications of Microbial Genomics summarizes this workshop.

Science
Author : John Michels (Journalist)
Publisher : N.A
Release Date : 2006
ISBN 10 :
Pages : 329 pages
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High-Throughput Protein Production and Purification: Methods and Protocols
Author : Renaud Vincentelli
Publisher : Methods in Molecular Biology
Release Date : 2020-07-19
ISBN 10 : 9781493996261
Pages : 537 pages
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The Philosopher's Index
Author : N.A
Publisher : N.A
Release Date : 2008
ISBN 10 :
Pages : 329 pages
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Vols. for 1969- include a section of abstracts.

Annual report
Author : South African Institute for Medical Research
Publisher : N.A
Release Date : 1999
ISBN 10 :
Pages : 329 pages
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Genomics, Proteomics and Vaccines
Author : Guido Grandi
Publisher : John Wiley & Sons
Release Date : 2004-08-13
ISBN 10 : 0470093927
Pages : 336 pages
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While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions