|Author||: Rebecca Sanft,Anne Walter|
|Publisher||: Academic Press|
|Release Date||: 2020-03-30|
|ISBN 10||: 0128195967|
|Pages||: 254 pages|
Exploring Mathematical Modeling in Biology through Case Studies and Experimental Activities provides supporting materials for courses taken by students majoring in mathematics, computer science or in the life sciences. The book's cases and lab exercises focus on hypothesis testing and model development in the context of real data. The supporting mathematical, coding and biological background permit readers to explore a problem, understand assumptions, and the meaning of their results. The experiential components provide hands-on learning both in the lab and on the computer. As a beginning text in modeling, readers will learn to value the approach and apply competencies in other settings. Included case studies focus on building a model to solve a particular biological problem from concept and translation into a mathematical form, to validating the parameters, testing the quality of the model and finally interpreting the outcome in biological terms. The book also shows how particular mathematical approaches are adapted to a variety of problems at multiple biological scales. Finally, the labs bring the biological problems and the practical issues of collecting data to actually test the model and/or adapting the mathematics to the data that can be collected. Presents a single volume on mathematics and biological examples, with data and wet lab experiences suitable for non-experts Contains three real-world biological case studies and one wet lab for application of the mathematical models Includes R code templates throughout the text, which are also available through an online repository, along with the necessary data files to complete all projects and labs
Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices). Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence. Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation
Fish travel in schools, birds migrate in flocks, honeybees swarm, and ants build trails. How and why do these collective behaviors occur? Exploring how coordinated group patterns emerge from individual interactions, Collective Animal Behavior reveals why animals produce group behaviors and examines their evolution across a range of species. Providing a synthesis of mathematical modeling, theoretical biology, and experimental work, David Sumpter investigates how animals move and arrive together, how they transfer information, how they make decisions and synchronize their activities, and how they build collective structures. Sumpter constructs a unified appreciation of how different group-living species coordinate their behaviors and why natural selection has produced these groups. For the first time, the book combines traditional approaches to behavioral ecology with ideas about self-organization and complex systems from physics and mathematics. Sumpter offers a guide for working with key models in this area along with case studies of their application, and he shows how ideas about animal behavior can be applied to understanding human social behavior. Containing a wealth of accessible examples as well as qualitative and quantitative features, Collective Animal Behavior will interest behavioral ecologists and all scientists studying complex systems.
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Accessible text features over 100 reality-based examples pulled from the science, engineering, and operations research fields. Prerequisites: ordinary differential equations, continuous probability. Numerous references. Includes 27 black-and-white figures. 1978 edition.
Focuses on research and development centers in the areas of medical and biomedical sciences including those in anatomy, biochemistry, clinical medicine, dentistry, drugs, genetics, immunology, neoplasms, pharmaceutical technology, and surgery.
What are "essential questions," and how do they differ from other kinds of questions? What's so great about them? Why should you design and use essential questions in your classroom? Essential questions (EQs) help target standards as you organize curriculum content into coherent units that yield focused and thoughtful learning. In the classroom, EQs are used to stimulate students' discussions and promote a deeper understanding of the content. Whether you are an Understanding by Design (UbD) devotee or are searching for ways to address standards—local or Common Core State Standards—in an engaging way, Jay McTighe and Grant Wiggins provide practical guidance on how to design, initiate, and embed inquiry-based teaching and learning in your classroom. Offering dozens of examples, the authors explore the usefulness of EQs in all K-12 content areas, including skill-based areas such as math, PE, language instruction, and arts education. As an important element of their backward design approach to designing curriculum, instruction, and assessment, the authors *Give a comprehensive explanation of why EQs are so important; *Explore seven defining characteristics of EQs; *Distinguish between topical and overarching questions and their uses; *Outline the rationale for using EQs as the focal point in creating units of study; and *Show how to create effective EQs, working from sources including standards, desired understandings, and student misconceptions. Using essential questions can be challenging—for both teachers and students—and this book provides guidance through practical and proven processes, as well as suggested "response strategies" to encourage student engagement. Finally, you will learn how to create a culture of inquiry so that all members of the educational community—students, teachers, and administrators—benefit from the increased rigor and deepened understanding that emerge when essential questions become a guiding force for learners of all ages.
This comprehensive summary of the state of the art and the ideas behind the reaction engineering approach (REA) to drying processes is an ideal resource for researchers, academics and industry practitioners. Starting with the formulation, modelling and applications of the lumped-REA, it goes on to detail the use of the REA to describe local evaporation and condensation, and its coupling with equations of conservation of heat and mass transfer, called the spatial-REA, to model non-equilibrium multiphase drying. Finally, it summarises other established drying models, discussing their features, limitations and comparisons with the REA. Application examples featured throughout help fine-tune the models and implement them for process design and the evaluation of existing drying processes and product quality during drying. Further uses of the principles of REA are demonstrated, including computational fluid dynamics-based modelling, and further expanded to model other simultaneous heat and mass transfer processes.