Parkinsons disease is a disabling neurological condition with both motor and non-motor symptoms for which no cure is available at this stage. This book is unique in covering the most important topics related to Parkinsons disease. Current research and updates about some non-motor symptoms, as well as surgical treatment of Parkinsons disease, in addition to the long term complications of pharmacological treatments have been presented. This book can be used by physicians, researchers and neuroscientists who want to learn new information about these topics related to Parkinsons disease. Authors of the individual chapters are well known in their fields and the book has been edited by a world renowned Parkinsons disease expert.
Parkinson's disease (PD) is the second most common neurodegenerative disorder results due to loss of dopamine producing brain cells. Knowledge relating to PD condition has been known since 5000BC, however no effective therapeutic strategies are available till today. Therefore it is important for neurobiologists to work further by taking advantage of modern scientific methods and develop appropriate therapeutic strategies. Efforts in this direction are worthy as they will reduce the burden of PD among elderly, who are already burdened with age related systemic degenerative processes. This book is a humble effort in that progressive direction. It has chapters covering multiple aspects relating to etiology, pathophysiology of PD, available and futuristic therapeutics strategies. Therefore it will be of interest to common man, biomedical researchers and clinicians. This is one small step in a direction "to reduce the burden of neurological disease."
This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.
Many patients experience sleep disturbances secondary to their primary illness and this often has a negative effect on their quality of life. This book provides an evidence-based introduction to the interface between sleep wide range of medical disorders. A clinically focused, comprehensive review for physicians and other health providers, this state-of-the-art reference can also serve as a textbook for those who wish to become familiar with the impact of sleep on quality of life.
|Author||: Dag Aarsland,Jeffrey Cummings,Daniel Weintraub,K. Ray Chaudhuri|
|Publisher||: Cambridge University Press|
|Release Date||: 2013-08-29|
|ISBN 10||: 1107039223|
|Pages||: 307 pages|
Psychiatric and cognitive changes are common in patients with Parkinson's disease and have key clinical consequences but, despite this, these symptoms are often under-diagnosed and under-treated, leading to increased morbidity and costs. With chapters focused on the major neuropsychiatric features, Neuropsychiatric and Cognitive Changes in Parkinson's Disease and Related Movement Disorders rectifies this deficit. Written by experts in the field, with a consistent focus on relevant clinical knowledge, it provides a comprehensive overview including all the major behavioral changes associated with movement disorders. The book provides broad, in-depth, accurate and up-to-date scientific information as well as crucial understanding and practical tools to help patients. The book is essential reading for clinicians working in neurology, psychiatry and geriatric medicine.
|Author||: Edgar Garcia-Rill|
|Publisher||: Academic Press|
|Release Date||: 2015-04-28|
|ISBN 10||: 0128016329|
|Pages||: 330 pages|
Waking and the Reticular Activating System in Health and Disease provides a comprehensive overview on the “activating properties of the RAS. In health, the RAS provides the basis against which we assess the external world, and in disease it distorts that world and shatters our self-image. This book describes the physiology of each process, how it is disturbed in each disorder, and what the most appropriate treatment should be. Dr. Garcia-Rill, along with contributions from leading specialists, discusses the understanding of the RAS as a system not only modulating waking, but also in charge of survival mechanisms such as fight vs flight responses and reflexes. The full spectrum of these functions helps explain the complexity of symptoms evident in such disorders as disparate as schizophrenia and Parkinson’s disease. The book reviews the mechanisms that control waking and arousal, and especially how those mechanisms malfunction in certain neurological and psychiatric disorders. First comprehensive overview on the RAS and its role in schizophrenia, major depression, autism, Parkinson’s, Alzheimer’s, and other neurologic and mental diseases Offers a new way of thinking about brain function and the role of the RAS in our waking lives Written by a leading translational neuroscience researcher with contributions by specialists in the field
This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.
Sleep and Neurologic Disease reviews how common neurologic illnesses, such as Parkinson's Disease and Alzheimer's dementia impact sleep. In addition, the book discusses how common primary sleep disorders influence neurologic diseases, such as the relationship between obstructive sleep apnea and stroke, as well as their association with various primary headache disorders and epilepsy syndromes. The utilization of sleep technology, such as polysomnography, multiple sleep latency testing, actigraphy, laboratory and CSF testing is also covered. The book is written for the practicing neurologist, sleep physician, neuroscientist, and epidemiologist studying sleep. Reviews how common neurological illnesses impact sleep and the impact sleep disorders have on neurologic disease Up-to-date, comprehensive overview written for practicing neurologists, sleep physicians, neuroscientists, and epidemiologists Includes informative discussions on sleep physiology, circadian rhythms, sleep and stroke, and treatment options for neurologists
Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders Covers multiple neurological disorders, including epilepsy, Alzheimer’s disease, Parkinson’s disease and autism
The chemical basis of human emotions has been an exciting aspect in biology. The "feel-good chemical" dopamine (DA) is a hormone and also a neurotransmitter, which performs a critical role in reward and movement control in the brain. DA also performs multiple other functions outside the brain. Regulating unrelated critical biological functions makes this chemical a vital factor for sustaining life in both health and disease. Dopamine - Health and Disease is an endeavour with an objective to understand and appreciate the biological functions of DA in human wellbeing and its potential utility in biomedical research. This effort will supplement scientific and non-scientific communities in stimulating a critical understanding of the biological purpose of "ticklish" DA, which eventually supports the human relentless effort to reduce the burden of disease. As the most exciting molecule,dopamine directly impacts day-to-day life. Anyone who has an eye for health and disease-related concepts will find this book a good read.