This new book reviews the latest advances in the embryology, genetics, diagnosis, imaging, and therapy of congenital heart disease. The international cast of authors has combined its talents to produce a unique, expert perspective. This publication arrives at a very exciting time when new genetic, imaging, and therapeutic developments are changing the field. It is relevant to pediatricians, internal medicine specialists, medical geneticists, both pediatric and adult cardiologists, embryologists, imaging physicians, and cardiac surgeons. The reader is taken on a journey that begins with a historical overview of congenital cardiovascular anomalies and ends with developments in stem cell and tissue engineering. In between are chapters on cardiac embryogenesis; epidemiology; genetic syndromes associated with cardiovascular anomalies; single gene disorders; cardiac imaging; surgical and interventional therapies; and ethical considerations.
This book combines an exceptional wealth of precise, exquisite schematic drawings and high-quality images with clear explanatory text in order to provide readers with a crisp and clear understanding of all aspects of congenital heart disease, from diagnosis to treatment and from the fetus to the adult. In format the book appears similar to a large collection of case reports covering all types of congenital heart disease, including complex lesions such as single ventricle and atrial isomerism. For each lesion, the illustrations are placed before the text so that the reader can gain a quick and general overview before going into more detail. The contents are as practical and concise as possible. The intention is that, despite its size, the book will serve as a handy reference for cardiologists, surgeons, intensivists, obstetricians specializing in fetal sonography, nurses, trainees, students, researchers, and even patients and their families. This is a “must-have” bedside reference in the cardiac ward, the ICU, and the fetal sonography room and will even be valuable in outpatient clinics.
|Author||: Michael A. Gatzoulis,Gary D. Webb,Piers E. F. Daubeney|
|Publisher||: Elsevier Health Sciences|
|Release Date||: 2017-02-02|
|ISBN 10||: 0702069310|
|Pages||: 576 pages|
Designed to meet the needs of clinicians working with adults with congenital heart disease, Diagnosis and Management of Adult Congenital Heart Disease , by Drs. Michael A. Gatzoulis, Gary D. Webb, and Piers E. F. Daubeney, offers essential guidance on the anatomical issues, clinical presentation, diagnosis, and treatment options available to practitioners today. This latest edition features completely updated content, including new information for nurses and nurse practitioners who, now more than ever, are playing an important role in the care of adults with CHD. You'll also access four new chapters, illustrated congenital defects, coverage of long-term outcomes, and much more. Drs. Gatzoulis, Webb, and Daubeney lead a team of experts ideally positioned to provide state-of-the-art global coverage of this increasingly important topic. Each disease-oriented chapter is written to a highly structured template and provides key information on incidence, genetics, morphology, presentation, investigation and imaging, and treatment and intervention. Congenital defects are illustrated with full-color line drawings and by the appropriate imaging modality (for example, EKG, x-ray, echocardiogram, MRI, CT, ). Provides coverage of long-term outcomes, including the management of pregnant patients and patients undergoing non-cardiac surgery. Features the addition of four new chapters: A Historic Perspective; Quality of Life in Patients with Pulmonary Hypertension; Psychosocial Issues in ACHD; Supportive and Palliative Care for End-Stage ACHD.
Congenital Heart Disease is a general term for a range of birth defects that affect the normal workings of the heart. It is one of the most common types of birth defect occurring in 1% of live births and affects up to 9 in every 1,000 babies born in the United Kingdom. It was estimated that 34.3 million people had a congenital heart abnormality in 2013. Abnormalities can arise in 3-5% of off spring in cases of de novo family history. Congenital heart disease was responsible for 223,000 deaths in 2010. This short volume details the common birth defects affecting the structure and functioning of the heart concentrating on the genetic basis and epidemiology, as well as risk factors, diagnostic modalities and treatment options.
|Author||: Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi|
|Release Date||: 2016-06-24|
|ISBN 10||: 4431546286|
|Pages||: 383 pages|
This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.
Highly Commended at the British Medical Association Book Awards 2016 The third edition of Anesthesia for Congenital Heart Disease, the recognized gold-standard reference in this field, offers a major update and expansion of the textbook to reflect the ongoing development of the practice of pediatric and congenital cardiac anesthesia and the burgeoning knowledge base in this exciting field. Includes two new chapters addressing key areas; anesthetic and sedative neurotoxicity in the patient with congenital heart disease, and anesthesia in the patient with pulmonary hypertension Now in full color, with over 200 illustrations and photographs Multiple-choice questions accompany each chapter covering the most crucial learning points to optimize the learning experience for readers at all levels
Nowadays, nobody can imagine practicing obstetrics without using obstetrical ultrasound. Working in the prenatal diagnosis field requires dedication, patience, skills, experience, caution, and empathy. The concept of this book was guided by the desire to provide some help to the ultrasound operators. On a daily basis, they are confronted with the challenging task of ruling out or suspecting/confirming the diagnosis of fetal anomalies, either structural or chromosomal. The chapters of this book contain objective and exhaustive updated reviews of the pertinent literature, so that the reader would have a wide reference basis on each subject. Yet, many authors scan the fetus themselves or are directly involved with managing pregnancies with structural malformations or chromosomal anomalies. They kindly shared their personal experience and lessons learned over the years. This book is beneficial for all the professionals working in the prenatal diagnosis.
This book describes the risks facing patients with congenital heart disease who wish to become pregnant and the ways in which these patients can best be followed and treated during pregnancy. In addition, the organization of care around the delivery is discussed in detail. The first section provides clear advice on pre-pregnancy risk estimation, counseling of patients, medication use, and inheritance. The specific risks associated with congenital heart defects of differing severity are then explained, with guidance on monitoring and management. The coverage includes simple lesions such as atrial and ventricular septal defects, conditions associated with moderate risk, including tetralogy of Fallot and coarctation, and complex disease such as a Fontan or Mustard repair. The final section is devoted to delivery and considers the mode of delivery, anesthetic use, and postpartum care. Readers will find much information that is underreported in the literature, and the book goes well beyond the European Society of Cardiology guidelines, for example, by considering medical conditions not defined as high risk and addressing the organization of care thoroughly.
Congenital Heart Disease and Neurodevelopment: Understanding and Improving Outcomes brings together the work of leading researchers from the U.K., Europe, and the U.S. to provide a comprehensive examination of the causes, risks, and neurodevelopmental and psychological outcomes in children with congenital heart disease. The book includes longitudinal studies which have tracked outcomes from birth through late childhood and explores the emergent phenotype and etiologies, risk, and protective factors that strengthen proposed models. Medical and surgical advances have meant that greater numbers of children with even the most severe congenital heart disease (CHD) now survive well into adulthood. Studies over the past 20 years have suggested certain neurodevelopmental and psychological features are common, with clinical interventions being internationally articulated. The U.K. Belfast Center has developed and evaluated unique early intervention programs to circumvent the common problems discerned and promote optimal adjustment and outcomes. The first edition of Congenital Heart Disease and Neurodevelopment: Understanding and Improving Outcomes describes these programs in detail and outlines promising results obtained by researchers worldwide. Such interventions, together with the U.S. consensus statement (Circulation, 2012) on neurodevelopmental screening, hold great promise for clinical interventions. Features input from leading research experts in the field Describes cutting-edge research on longitudinal studies that link neurodevelopmental phenotypes with cutting-edge neuroimaging studies Discusses the first series of early intervention studies developed in Belfast targeted at key developmental transitions—birth and diagnosis, early childhood, and adolescence Includes clinical implications and action points in each section Features generalizable potential of interventions across other pediatric populations
Here's the thoroughly revised and expanded 2nd Edition of the definitive resource on adult congenital heart disease! Written by leading authorities in the field, this book presents a comprehensive examination of the subspecialty, including basic unoperated malformations, medical and surgical perspectives, postoperative residua and sequelae, and more. All chapters have been painstakingly rewritten * and all illustrations meticulously reviewed * to ensure they reflect the full range of new advances in the field. two new chapters, Transthoracic and Transesophageal Echocardiology Imaging, and Neurologic Disorders. Presents a comprehensive examination of all aspects of the field, including basic unoperated malformations, medical and surgical perspectives, postoperative residua and sequelae, and more. Contains a separate chapter on the noncardiac disorders that make cyanotic congenital heart disease in adults a multi-system disorder. Clarifies important material with more than 530 illustrations - many brand new - that depict virtually all imaging modalities in current use, plus much more. Offers a great deal of previously unpublished data throughout. Discusses topics not comprehensively covered in other texts, such as Psychosocial Disorders and Normal Myocardiac Growth and the Development and Regression of Increased Ventricular Mass. Includes extensive references to make further reading easy.
Introductory Chapter: Congenital Heart Disease.
|Author||: Horst Sievert,Shakeel Qureshi,Neil Wilson,Ziyad M. Hijazi|
|Publisher||: CRC Press|
|Release Date||: 2007-03-20|
|ISBN 10||: 9780203018262|
|Pages||: 672 pages|
Percutaneous Interventions for Congenital Heart Disease is written for pediatric cardiologists specializing in interventional cardiology and need a step-by-step guide to carrying out procedures, as well as adult cardiologists. Covering all kinds of interventions in congenital heart disease and the new field of structural heart disease, the book examines: Acquired valvular heart disease Post-myocardial infarction ventricular septal defects PFO closure Closure of the left atrial appendage Paravalvular leak closure Techniques for treating diseases of the aorta Hybrid procedures An essential text on how to perform interventional cardiology for congenital heart disease in both the pediatric and adult patient, this expertly written work will help to overcome barriers between pediatric and adult cardiologists, and pave the way for new cardiovascular interventionalists.
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
The field of cardiothoracic surgery continues to evolve at a rapidly expanding rate. New technologies are under constant development and as patients present with more advanced pathophysiology and complex comorbidities, management becomes more dependent on multi-disciplinary Teams. While there are a variety of innovative and high-profile topics that dominate the literature and the interests of clinicians, sometimes is it the basics both in terms of acute and sometimes unusual problems that often challenge cardiothoracic surgeons on a day to day basis. The goal of Principles and Practice of Cardiothoracic Surgery is to hopefully highlight the current state of the art management of these problems.
This book provides a concise yet comprehensive source of current information on Down syndrome. It focuses on exciting areas of research on chromosome editing, neurogenomics and diseases associated with Down syndrome. Research workers, scientists, medical graduates and physicians will find this book as an excellent source for consultation and references. Key features of this book are chromosome engineering in Down syndrome, mental retardation and cognitive disability, prenatal diagnosis and diseases associated with Down syndrome. Although aimed primarily for research workers on Down syndrome, we hope that the appeal of this book will extend beyond the narrow confines of academic interest and be exciting to wider audience, especially parents, relatives and health care providers who work with infants and children with Down syndrome.
Congenital heart disease with its worldwide incidence of 1% is themost common inborn defect. Increasingly, patients are living intoadulthood, with ongoing congenital heart and other medical needs.Sadly, only a small minority have specialist follow-up. However,all patients see their family doctor and may also seek advice fromother health professionals. This practical guide with its straightforward a,b,c approach iswritten for those professionals. Special features of this book: • Introduces the principles of congenital heart diseaseand tells you whom and when to refer for specialist care • Discusses common congenital heart lesions in a practical,easy-to-follow way, with an emphasis on diagnosis and managementissues • Includes an extensive chapter on 'Pregnancy andContraception' (by Philip J. Steer), essential both for familyplanning and for managing safely the pregnant woman with congenitalheart disease • Includes chapters on non-cardiac surgery and lifestyleissues such as work, insurability, travel and driving • Provides invaluable information on dealing with commonemergencies; what to do and what not to do With a wealth of illustrations (including diagrams, EKGs, CXRs,Echos and cardiac MRIs) and with key point tables, this is anessential guide for all health care professionals managing patientswith adult congenital heart disease.
|Author||: Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent|
|Publisher||: World Bank Publications|
|Release Date||: 2017-11-17|
|ISBN 10||: 1464805202|
|Pages||: 466 pages|
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
This book provides the theoretical and practical basis of technical nursing in congenital heart disease; it is intended for nurses and nursing students, and for anyone involved in the treatment of these patients. The improvements in diagnosis and management of patients with congenital heart disease (CHD) are due to the recent advances in cardiac surgery and interventional cardiology and have meant that an increasing number of infants are reaching adolescence and adulthood. This manual is a practical and easy-to-use guide, which promotes effective cooperation between health professionals. Congenital heart disease is a disorder that is present at birth, and studies show that the incidence is around eight cases per thousand live births. The heart is formed during the first four - ten weeks of gestation, and alterations to this process can affect normal development, leading to heart defects. There are various types of heart defects: abnormalities that affect a single part of the heart (for example a valve) but also, highly complex abnormalities where there is severe damage to the cardiac architecture. The seriousness of the disease and the effects on child health vary: some forms have no real impact on child health and allow a normal life, while others are incompatible with life.
|Author||: Robert M. Freedom,Shi-joon Yoo,Haverj Mikailian,William G. Williams|
|Publisher||: John Wiley & Sons|
|Release Date||: 2008-04-15|
|ISBN 10||: 0470986891|
|Pages||: 904 pages|
Exhaustive in its scope, this book provides a comprehensive study of the natural and modified history of congenital heart disease. Focusing particularly on the discussion of fetal and post-natal outcomes, the contributors seek to place developments in historical perspective. Virtually all surgical and catheter-based strategies to enhance outcomes of all forms of congenitally malformed heart are analysed, covering the morphology and genetic basis of each particular abnormality, and issues that were germane to evolving different therapeutic strategies. Using data from the records of the Toronto Hospital for Sick Children, contributors highlight the complications of the various forms of therapies and identifies particular risk factors for mortality and morbidity.