Coeliac Disease and Gluten-Related Disorders provides an updated and comprehensive overview on the crucial aspects and clinical management of gluten-related disorders. It provides an overview of the scientific background, mechanisms involved, and emphasizes the translational effect of research on clinical practice. Highlighted throughout are insights into future research areas likely to have a crucial impact in the clinical management of these common conditions. The book is perfect for researchers and gastroenterologists involved in Coeliac Disease and other gluten-related disorders. Presents both research and clinically based perspectives on the most relevant issues of gluten-related disorders Provides a wide-ranging discussion and the most updated opinions by international experts in the field of coeliac disease and gluten-related disorders Translates the latest research insights into practical suggestions for specialists
Celiac disease is a systemic autoimmune process and appears in genetically predisposed individuals, with a well-known cause, consisting in a permanent intolerance to gluten, a protein contained in the flour of wheat, rye, barley and oats. Worldwide celiac disease affects to 1% of the Caucasian and there is recent evidence that the disease is increasing in USA and Finland among other regions in the world. It is considered to be the most prevalent disease with a genetic predisposition. The clinical forms of presentation are varied. The classical form consisting of diarrhea, anemia and failure to thrive is still common in children, but in the adult patients the symptoms resemble the irritable bowel syndrome. Mono-symptomatic forms with extra-intestinal manifestations are frequent. Hematological, cutaneous, articular, hepatic, bone and neurological manifestations are often described. This protean presentation and the lack of awareness explain the delay in diagnosis and suggest that screening in high-risk groups is indicated. The publication of this book written mainly by Spanish and Latin-American clinicians, researchers, and teachers, demonstrates the wide interest and the involvement of different disciplines that are necessary to understand celiac disease and gluten-related pathologies, such as non-celiac gluten-sensitivity. This has a great impact in the general public and in the industry. However, the knowledge of non-celiac gluten-related pathologies remains scarce but presently in the process of being properly defined. This book also highlights the importance of recognizing non-celiac gluten-sensitivity and briefly discusses a new definition. It also provides some perspectives to take into account when studying celiac disease in China and Central America. It describes new observations in Mexico, El Salvador and Costa Rica. The psychosocial impact as studied and reported by Argentinean investigators also adds to the value of this book. Written with a multidisciplinary team, we think that this book could be of interest to a great variety of medical specialists. Due to the systemic nature and variable presentation of celiac disease it certainly is of interest to pediatricians, gastroenterologists, hepatologists, specialists in internal medicine, general practitioners as well as hematologists, immunologists, geneticists, pathologists, rheumatologists, dermatologists, neurologists, gynecologists, neurologists, psychiatrists, psychologists, orthopedic surgeons, specialists in rehabilitation medicine, endocrinologists. Being gluten the cause of these disorders, the food industry, dietitians and nutritionists will benefit from the valuable information presented in this book.
A Clinical Guide to Gluten-Related Disorders provides primary health care providers the succinct material they need to immediately evaluate and support their patients. Gluten-related disorders have a wide presentation, and this text covers the recognition, evaluation, and multi-disciplinary approach to the management of disease. Readers will benefit from the general overview of gluten intolerance and from the common sense approach to developing treatment and dietary plans. Clinical vignettes offer clinicians real-life scenarios to help put the disease and its treatment in context for their patients.
Gluten-related disorders are prevalent among human societies, specifically in developing countries. These diseases have similar clinical manifestations and although they are characterized by a specific pathophysiological response to ingestion of gluten, differential diagnosis of these disorders is very challenging and failure to diagnosis and treat these disorders at an early stage, can lead to irreparable health and cost damages. Gluten Related Disorders: Diagnostic Approaches, Treatment Pathways and Future Perspectives reports up-to-date scientific findings within a historical perspective to identify the main differences and distinctive features of each of these diseases leading to better diagnosis and treatment options as well as pathogenesis of gluten disorders for use in future research endeavors. This reference is perfect for researchers, scientists and medical practitioners currently addressing gluten-related diseases. Delivers a wide perspective of gluten-related disorders highlighting the differences and overlaps in clinical presentations of these disorders, aiding in the process of differential diagnosis Offers the pathogenesis of gluten disorders for use in future research endeavors Provides a comprehensive overview on all aspects of gluten-related disorders incorporating several up-to-date scientific findings bringing recognition to the main differences and distinctive features between the diseases
Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities is a unique reference work—the first to integrate the insights of the causes and effects of celiac disease from the chemistry of reaction-causing foods to the diagnosis, pathogenesis, and symptoms that lead to proper diagnoses and treatment. With an estimated three million people in the United States alone affected by celiac disease, an autoimmune digestive disease, only five percent are properly diagnosed. Drawing on the connection between foods containing gluten and the resulting symptoms, this resource offers distinctive information that directly explores and links food science, medical diagnostics, and treatment information. A helpful tool for researchers and medical practitioners alike, Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities helps refine research targets, and provides a comprehensive overview on the multidisciplinary approaches to all crucial aspects related to celiac disease. Presents key information from medical and food science research, as well as provides clinical insights Provides direct corollary insights between source and symptom Written by experts whose detailed experiments and results have shaped our understanding of celiac disease
This unique book is a first-of-its-kind resource, comprehensively guiding readers through the epidemiology, pathophysiology, recent diagnostic criteria, and management options for patients with Food Protein-Induced Enterocolitis Syndrome (FPIES). Food-Protein Induced Enterocolitis Syndrome: Diagnosis and Management opens with a historical perspective of this condition, before moving into discussions of epidemiology and pathophysiology. FPIES can be difficult to diagnose as the symptoms overlap with multiple other conditions, and so clear differential diagnosis will be reviewed for both chronic FPIES, as well as acute FPIES. Later chapters are case-based, providing detailed multiple perspectives on the diagnosis and management of FPIES in patients with varying complicating factors and severity. Later chapters will tackle issues of quality of life in patient care, nutritional management for patients, and discussing working with parents and families to improve communication and at-home care. Parents, families and caregivers will also find chapters useful and relatable. A final chapter will look to the future of FPIES, addressing new research, guidelines, and implications for clinicians working with pediatric patients with FPIES, and for their families. Concise and practical, this book will be an ideal reference for allergists, pediatricians, family practice clinicians, gastroenterologists, nutritionists, and all other health care providers who encounter FPIES, and assist them in providing up-to-date, quality care for pediatric patients affected by this condition.
Practical, delicious ways to manage a gluten-free diet. If you have a wheat allergy, gluten intolerance, celiac disease, or just want to enjoy the benefits of a diet free of wheat, barley, and rye, then this handy pocket guide gets you on the gluten-free path. You’ll get a handle on the whos, whats, whys, and hows of going gluten-free as well as trusted advice on how to manage gluten sensitivity. Packed with practical advice ranging from what to eat and what to avoid to how to shop and cook, this book gets you started living — and loving — a gluten-free lifestyle.
New from Mayo Clinic-the essential guide to living gluten-free. Whether diagnosed with celiac disease or just deciding if a gluten-free diet is right for you, Mayo Clinic Going Gluten-Free will help you create and maintain a gluten-free lifestyle. Both authoritative and approachable, the book includes core medical information on celiac disease in addition to focusing on practical, everyday issues, such as: --Determining if gluten-free is right for you --Common signs, symptoms and myths of celiac --Dealing with celiac if you are newly diagnosed --Maintaining a gluten-free lifestyle while traveling, during the holidays, on-the-go and at college --Helping your child manage a gluten-free diet --Properly reading and understanding food labels --A few recipes and meals to jumpstart your gluten-free life
Today, supermarkets have dedicated gluten-free aisles, restaurants highlight gluten-free dishes on their menus, and millions of people have cut gluten out of their diets in the hopes of boosting health and losing weight. But despite all the attention, gluten confusion still reigns. Enter cardiologist Arthur Agatston, MD, author of the groundbreaking The South Beach Diet. With that book, Dr. Agatston ended the diet debates and cleared up the high-carb versus low-carb confusion. In The South Beach Diet Gluten Solution, he does the same for gluten, demystifying the effects of the difficult-to-digest protein in wheat and some other grains. The truth is, not everyone needs to give up gluten permanently—nor does doing so guarantee weight loss. With Dr. Agatston's phased Gluten Solution Program, based on proven South Beach Diet eating principles, you'll be able to determine your own level of gluten sensitivity—and you'll drop up to 10 pounds in just two weeks. What makes Dr. Agatston's approach unique is that he shows you how to become gluten aware, not gluten phobic. He shares his own personal journey to gluten awareness and explores the latest research to determine the real connection between gluten and health. He explains that a number of factors, including our vast overconsumption of highly processed grains, have increased the incidence of gluten sensitivity and celiac disease. These conditions contribute to a host of health issues, including brain fog, mood swings, digestive disorders, joint pain, and skin problems. You can find relief from these and other symptoms by following the South Beach Diet Gluten Solution Program. With detailed daily meal plans, tips for traveling and dining out, inspiring stories, and 20 delicious recipes (that sacrifice neither taste nor health), The South Beach Diet Gluten Solution gives you everything you need to feel great, lose weight, and navigate the gluten-free world with ease.
World-renowned gluten-related disorders expert Dr. Alessio Fasano presents the groundbreaking roadmap to a gluten-free lifestyle, and how millions can live better by going gluten free. For centuries, bread has been known as the "staff of life." But for millions of Americans affected by gluten-related disorders, consuming gluten, the complex protein found in wheat, rye, and barley, can be hazardous to their health. In a recent poll presented by Scientific American, over 30% of Americans reported wanting to cut down or eliminate gluten from their diets; the gluten-free market is a $6.3 billion industry and continues to expand. Now, in Gluten Freedom, Alessio Fasano, MD, world-renowned expert and founder of Massachusetts General Hospital's Center for Celiac Research, reveals the latest developments in scientific research and treatment, and the answers they provide for this rapidly expanding audience. This groundbreaking, authoritative guide is an invaluable roadmap for the newly diagnosed, for those already dealing with gluten-related issues, and for anyone who thinks they may have an issue with gluten. Distinguishing scientific fact from myth, Gluten Freedom explains the latest research, diagnostic procedures, and treatment/diet recommendations, helping consumers make the best choices for themselves and their families. Gluten Freedom also discusses important nutritional implications for behavior-related diagnoses such as autism and conditions such as depression, anxiety, and "foggy mind." Other highlights include: - The differences between celiac disease, gluten sensitivity, and wheat allergy - Current best practices for gluten-related disorders at any age - Practical information on setting up a gluten-free kitchen, reading labels, and staying safe and healthy in a world filled with hidden sources of gluten - The psychological impact of a diagnosis and its effect on a family - Groundbreaking research for prevention and therapy - Reliable and accurate resources for patients, parents, and physicians - And even recipes for an authentic gluten-free Italian dinner from Dr. Fasano's home kitchen
Celiac disease (CD) occurs in about 1% of people worldwide. Diagnosis rates are increasing due to a true rise in incidence, rather than increased awareness and detection. CD affects genetically susceptible individuals who are triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal chronic inflammation, and most patients have circulating antibodies against tissue transglutaminase. Our understanding of the basic and clinical aspects of CD increases, which is as a major health problem of almost global occurrence. Case finding, distinguishing CD from other gluten-sensitive conditions, better care, and balanced use of resources are the current challenges.
What do osteoporosis, anemia, diabetes and depression have in common? They can all be caused by celiac disease. Celiac disease, also know as gluten intolerance, is a major problem for millions of Americans. The Celiac Disease Foundation estimates that 2 million adults, children, and infants, or 1 in 133 people in the United States, have celiac disease. Celiac disease is hereditary and can affect entire families. This digestive disorder is caused by a sensitivity to the protein gluten in wheat flour, which in turn can damage the small intestine and interferes with the absorption of nutrients from food. Symptoms range from diarrhea, weight loss, and abdominal pain to fatigue, depression, and malnutrition. Celiac Disease: A Guide to Living with Gluten Intolerance is the first book on this important topic co-written by a nurse, a dietician, and a clinical pharmacist. The authors' diverse backgrounds ensure complete and clear information on all aspects of this disease, including symptoms, diagnosis, management, complications, and current research. While many cookbooks and dietary manuals on gluten intolerance exist, Celiac Disease is the only book to educate individuals on how to live fully and richly while maintaining a gluten-free lifestyle. Not only will readers learn how to set up and maintain a gluten-free kitchen, but they will also find strategies for tackling emotional issues, nutrition and dietary guidelines, handling dining outside the home, and parental advice on raising a celiac child. In addition, a chapter on medications and a list of educational resources will aid readers in their transition to a gluten-free lifestyle. Celiac Disease: A Guide to Living with Gluten Intolerance is an indispensable guide for patients, dieticians, nutritionists and medical professionals working with celiac patients.