|Author||: Paolo Netti,Maurizio Ventre|
|Publisher||: Woodhead Publishing|
|Release Date||: 2020-11-26|
|ISBN 10||: 0081029381|
|Pages||: 258 pages|
Cell Instructive Materials to Control and Guide Cell Function: Programmable Bioactive Interfaces looks at the key determinants of the dynamic interface between cell and materials and how this can be applied in developing new, bioactive biomaterials surfaces. The interface between cell and synthetic materials has attracted considerable scientific and technological interest, leading to the awareness that functional interfaces can actively guide and control specific adhesion and recognitions events. Introduces readers to the fundamentals of complex cell-material interface dynamics Provides valuable tools for the control of the interfacial dynamics to instruct and control cells or tissues functions Covers the prospect of encoding specific cell instructions on, or within, a biomaterial by micro- and nano-patterning materials features
|Author||: Roberto Cingolani|
|Release Date||: 2014-06-04|
|ISBN 10||: 3319049240|
|Pages||: 334 pages|
The present book discusses topics related to research and development of materials and devices at nanoscale size and their respective application in medicine and biomedicine. The individual chapters give a detailed state of the art overview to the distinct topic. Apparently disconnected fields - life sciences, biomedicine, chemistry, physics, medicine and engineering - will be bridged with a highly interdisciplinary view onto each subject.
|Author||: Giuseppe Orlando|
|Publisher||: Academic Press|
|Release Date||: 2013-10-11|
|ISBN 10||: 012398520X|
|Pages||: 1050 pages|
Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions
This book is a printed edition of the Special Issue " Hydrogels in Tissue Engineering" that was published in Gels
This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.
|Author||: Ratmir Derda|
|Release Date||: 2008|
|Pages||: 271 pages|
|Author||: Justin Brown,Sangamesh Kumbar,Brittany Banik|
|Publisher||: Academic Press|
|Release Date||: 2016-11-03|
|ISBN 10||: 0128033991|
|Pages||: 252 pages|
Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine Focuses on how materials of structures can be designed to be resistant while promoting viable grafts Contains major tissue types that are covered with a strategy for each material and structure
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume focuses on stem cell regulators. Longest running series published by Academic Press Contributions by leading international authorities
|Author||: Mario Barbosa,M Cristina L Martins|
|Publisher||: Woodhead Publishing|
|Release Date||: 2017-09-25|
|ISBN 10||: 008100852X|
|Pages||: 390 pages|
Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers
In order to grow replacement tissues, 3D scaffolds are widely used as a template for tissue engineering and regeneration. These scaffolds, which are typically ‘seeded’ with cells, support the growth of new tissues. However, in order to achieve successful tissue growth, the scaffold must meet specific requirements and are often ‘functionalized’ to accentuate particular properties. Functional 3D tissue engineering scaffolds: materials, technologies, and applications, is a comprehensive review of functional 3D scaffolds, providing information on the fundamentals, technologies, and applications. Part 1 focuses on the fundamentals of 3D tissue scaffolds, examining information on materials, properties, and trends. Part 2 discusses a wide range of conventional technologies for engineering functional 3D scaffolds, leading the way to a discussion on CAD and advanced technologies for functional 3D scaffold engineering. Chapters in part 3 study methods for functionalizing scaffolds to support a variety of in vivo functions whilst the final set of chapters provides an important review of the most significant applications of functional 3D scaffolds within tissue engineering. This book is a valuable resource for biomaterial scientists and biomedical engineers in academia and industry, with interests in tissue engineering and regenerative medicine. Provides a self-contained work for the field of biomaterials and tissue engineering Discusses all the requirements a scaffold must meet and a wide range of strategies to create them Highlights significant and successful applications of functional 3D scaffolds
Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering
First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references
Takashi Hoshiba and Tetsuji Yamaoka have brought together, for the first time, leading contributors to provide a fundamental guide to the decellularized extracelluar matrix. Focussing on the sources of dECM, preparation, characterization and applications of dECM in regenerative medicine and biological systems, this is a must-have resource for those working in regenerative medicine and tissue engineering.
Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs
-Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology
A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer's disease, and Parkinson's disease. Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In this book, neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer's disease, Parkinson's disease, and spinal cord injuries. Certainly brain disorders are in need of effective treatments. These disorders don't just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells—and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinson's and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body. New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair?
Pacific Northwest National Laboratory, Richland, WA. Presents the proceedings of the Pacific Northwest National Laboratory inaugural meeting of the Northwest Symposium for Systems Biology, held October 17-18, 2002, in Richland, Washington.