Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment. Provides information on camptothecin producing plants and their anticancer properties for the development of new treatments Discusses new applications of camptothecin based on recent biotechnology advancements Presents comprehensive information on the pharmacology of camptothecin for leveraging new anticancer drugs developments
|Author||: Nitish Kumar|
|Release Date||: 2018-09-11|
|ISBN 10||: 9811305358|
|Pages||: 665 pages|
For the majority of the world’s population, medicinal and aromatic plants are the most important source of life-saving drugs. Biotechnological tools represent important resources for selecting, multiplying and conserving the critical genotypes of medicinal plants. In this regard, in-vitro regeneration holds tremendous potential for the production of high-quality plant-based medicines, while cryopreservation – a long-term conservation method using liquid nitrogen – provides an opportunity to conserve endangered medicinal and aromatic plants. In-vitro production of secondary metabolites in plant cell suspension cultures has been reported for various medicinal plants, and bioreactors represent a key step toward the commercial production of secondary metabolites by means of plant biotechnology. Addressing these key aspects, the book contains 29 chapters, divided into three sections. Section 1: In-vitro production of secondary metabolites Section 2: In-vitro propagation, genetic transformation and germplasm conservation Section 3: Conventional and molecular approaches
This 43rd volume of RAP includes a total of seven articles based on talks presented at the 50th Anniversary meeting of the PSNA, which was held at the Fairmont Orchid, in Waikoloa, Hawai’i, USA. These seven Perspectives give a very good picture of the breadth of plant (bio)chemistry research in North America, which is also indicative of the state of the field worldwide. Each of these articles describes the integration of several different approaches to ask and then answer interesting questions regarding the function of interesting plant metabolites, either in the plant itself or in interactions with the environment (natural setting or human health application). Two Perspectives outline very clearly the power of approaching biological questions from a modern, “omics” or systems biology approach. Beale and Ward outline how metabolomics approaches can be brought to bear on plant biosynthetic questions and quickly lead to important advances in our understanding or how plants produce important metabolites. Zandkarimi et al. outline the integration of ion mobility spectrometry into mass spectrometry-based metabolomics investigations and show clearly how powerful those two spectrometric technologies can be when used together.
Natural Products: Discourse, Diversity andDesign provides an informative and accessible overview ofdiscoveries in the area of natural products in the genomic era,bringing together advances across the kingdoms. As genomicsdata makes it increasingly clear that the genomes of microbes andplants contain far more genes for natural product synthesis thanhad been predicted from the numbers of previously identifiedmetabolites, the potential of these organisms to synthesize diversenatural products is likely to be far greater than previouslyenvisaged. Natural Products addresses notonly the philosophical questions of the natural role of thesemetabolites, but also the evolution of single and multiplepathways, and how these pathways and products may be harnessed toaid discovery of new bioactives and modes of action. Edited by recognized leaders in the fields of plant andmicrobial biology, bioorganic chemistry and natural productschemistry, and with contributions from researchers at top labsaround the world, Natural Products isunprecedented in its combination of disciplines and the breadth ofits coverage. Natural Produces: Discourse, Diversity andDesign will appeal to advanced students andexperienced researchers, from academia to industry, in diverseareas including ecology, industrial biotechnology, drug discovery,medicinal chemistry, agronomy, crop improvement, and naturalproduct chemistry.
Besides, recently molecular biology has assumed great importance with respect to plant biotechnology. The present book amalgamates all three aspects into one, practical applications of various techniques being the need of the hour. It discusses micropropagation studies on several crop plants, molecular basis of understanding various life processes including molecular basis of somatic embryogenesis and other physiological and biochemical processes having significant biotechnological applications. It also includes in vitro studies of some important plants like Aloe vera, Simmondsia chinensis, Anacyclus pyrethrum and Crataeva nurvala, Arachis hypogaea L., Phoenix dactylifera, Dendrocalamus asper, Asparagus adescendens Roxb., natural products of plant origin with their therapeutic potential and biotechnological production, genome analysis of crop plants with future applications in biotechnology etc.
These book series cover the distribution, economic importance, conventional propagation, micropropagation, tissue culture studies, and in vitro production of important medicinal and other pharmaceutical compounds in various medicinal and aromatic crops.
This book on medicinal plant biotechnology covers recent developments in this field. It includes a comprehensive up-to-date survey on established medicinal plants and on molecules which gained importance in recent years. No recently published book has covered these carefully selected topics. The contributing scientists have been selected on the basis of their involvement in the related plant material as evident by their internationally recognised published work.
Laboratory culture. Nutrition and metabolism. Secondary metabolism and biotransformation. Selection of plant cell lines which accumulate compounds. Storage of plant cell lines. Environmental factors. Light. Temperature, aeration and pH. Mass culture systems for plant cell suspensions. Industrial and government research. Product cost analysis. Products.
"The scope of the journal extends from plant molecular biology through classical botany to taxonomy and ecology."--TEPS Web site
|Author||: Plant Growth Regulation Society of America. Meeting|
|Release Date||: 2000|
|Pages||: 329 pages|
Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.