Biophotonics, Tryptophan and Disease is a comprehensive resource on the key role of tryptophan in wide range of diseases as seen by using optics techniques. It explores the use of fluorescence spectroscopy, Raman, imaging techniques and time-resolved spectroscopy in normal and diseased tissues and shows the reader how light techniques (i.e. spectroscopy and imaging) can be used to detect, distinguish and evaluate diseases. Diseases covered include cancer, neurodegenerative diseases and other age-related diseases. Biophotonics, Tryptophan and Disease offers a clear presentation of techniques and integrates material from different disciplines into one resource. It is a valuable reference for students and interdisciplinary researchers working on the interface between biochemistry and molecular biology, translational medicine, and biophotonics. Shows the key role of tryptophan in diseases Emphasizes how optical techniques can be potent means of assessing many diseases Points to new ways of understanding autism, aging, depression, cancer and neurodegenerative diseases
Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.
This third volume in the series represents the Proceedings of the 3rd International Nanophotonics Symposium, July 6-8, 2006, Icho-Kaikan, Osaka University, Osaka, Japan. Over a two-day symposium, distinguished scientists from around the world convened to discuss the latest progress in this field and the conclusions have been summarised in Nano Biophotonics: Science and Technology. The contents of this book have been compiled by invited lecturers, research members of the relevant projects/program, and some of general participants. The book has 27 chapters which are classified into 4 parts; nano bio-spectroscopy, nano bio-dynamics, nano bio-processing, and nano bio-devices. * Bridges the gap between conventional photophysics & photochemistry and nanoscience * Continuing the series that focuses on 'hot' areas of photochemistry, optics, material science and bioscience
Biophotonics for Medical Applications presents information on the interface between laser optics and cell biology/medicine. The book discusses the development and application of photonic techniques that aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states. Chapters cover the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications. Presents information on the interface between laser optics and cell biology/medicine Discusses the development and application of photonic techniques which aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states Presents the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications
Biophotonics involves understanding how light interacts with biological matter, from molecules and cells, to tissues and even whole organisms. Light can be used to probe biomolecular events, such as gene expression and protein–protein interaction, with impressively high sensitivity and specificity. The spatial and temporal distribution of biochemical constituents can also be visualized with light and, thus, the corresponding physiological dynamics in living cells, tissues, and organisms in real time. Light can also be used to alter the properties and behaviors of biological matter, such as to damage cancerous cells by laser surgery or therapy, and manipulate the neuronal signaling in a brain network. Fueled by the innovations in photonic technologies in the past half century, biophotonics continues to play a ubiquitous role in revolutionizing basic life science studies as well as biomedical diagnostics and therapies. Advancements in biophotonics in the past few decades can be seen not only in biochemistry and cell/molecular biology, but also in numerous preclinical applications. Researchers around the world are searching for ways to bring biophotonic technologies into real clinical practices, particularly cellular and molecular optical imaging. Meanwhile, emerging technologies, such as laser nanosurgery and nanoplasmonics, have created new insights for understanding, monitoring, and even curing diseases on a molecular basis. This book presents the essential basics of optics and biophotonics to newcomers (senior undergraduates or postgraduate researchers) who are interested in this multidisciplinary research field. With stellar contributions from leading experts, the book highlights the major advancements in preclinical diagnostics using optical microscopy and spectroscopy, including multiphoton microscopy, super-resolution microscopy, and endomicroscopy. It also introduces a number of emerging techniques and toolsets for biophotonics applications, such as nanoplasmonics, microresonators for molecular detection, and subcellular optical nanosurgery.
Neurophotonics and Biomedical Spectroscopy addresses the novel state-of-the-art work in non-invasive optical spectroscopic methods that detect the onset and progression of diseases and other conditions, including pre-malignancy, cancer, Alzheimer’s disease, tissue and cell response to therapeutic intervention, unintended injury and laser energy deposition. The book then highlights research in neurophotonics that investigates single and multi-photon excitation optical signatures of normal/diseased nerve tissues and in the brain, providing a better understanding of the underlying biochemical and structural changes of tissues and cells that are responsible for the observed spectroscopic signatures. Topics cover a wide array of well-established UV, visible, NIR and IR optical and spectroscopic techniques and novel approaches to diagnose tissue changes, including: label free in vivo and ex vivo fluorescence spectroscopy, Stoke shift spectroscopy, spectral imaging, Resonance Raman spectroscopy, multiphoton two Photon excitation, and more. Provides an overview of the spectroscopic properties of tissue and tissue-light interaction, describing techniques to exploit these properties in imaging Explores the potential and significance of molecule-specific imaging and its capacity to reveal vital new information on nanoscale structures Offers a concise overview of different spectroscopic methods and their potential benefits for solving diagnostic and therapeutic problems
Paras Prasad’s text provides a basic knowledge of a broadrange of topics so that individuals in all disciplines can rapidlyacquire the minimal necessary background for research anddevelopment in biophotonics. Introduction to Biophotonics serves asboth a textbook for education and training as well as a referencebook that aids research and development of those areas integratinglight, photonics, and biological systems. Each chapter contains atopic introduction, a review of key data, and description of futuredirections for technical innovation. Introduction to Biophotonicscovers the basic principles of Optics Optical spectroscopy Microscopy Each section also includes illustrated examples and reviewquestions to test and advance the reader’s knowledge.Sections on biosensors and chemosensors, important tools forcombating biological and chemical terrorism, will be of particularinterest to professionals in toxicology and other environmentaldisciplines. Introduction to Biophotonics proves a valuablereference for graduate students and researchers in engineering,chemistry, and the life sciences.
From the Lab to Clinical Settings—Advances in Quantitative, Noninvasive Optical Diagnostics Noninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of new therapeutic targets for drug discoveries. Natural Biomarkers for Cellular Metabolism: Biology, Techniques, and Applications delves into the current state of knowledge on intrinsic fluorescent biomarkers and highlights recent developments in using these biomarkers for the metabolic mapping and clinical diagnosis of healthy and diseased cells and tissues. Autofluorescent Biomarkers for Biomedical Diagnostics The book’s first section introduces the fundamentals of cellular energy metabolism as well as natural biomarkers within the context of their biological functions. The second section outlines the theoretical and technical background of quantitative, noninvasive, autofluorescence microscopy and spectroscopy methods, including experimental design, calibration, pitfalls, and remedies of data acquisition and analysis. The last two sections highlight advances in biomedical and biochemical applications, such as monitoring stem cell differentiation in engineered tissues and diagnosing cancer and ophthalmic diseases quantitatively and noninvasively. Tailored to Interdisciplinary Researchers Covering cell biology, imaging techniques, and clinical diagnostics, this book provides readers with a complete guide to studying cellular/tissue metabolism under healthy, diseased, and environment-induced stress conditions using natural biomarkers. The book is designed for graduate and advanced undergraduate students, biophysics instructors, medical researchers, and those in pharmaceutical R&D.
This book provides a comprehensive overview of laser sources and their applications in various fields of science, industry, and technology. After an introduction to the basics of laser physics, different laser types and materials for lasers are summarized in the context of a historical survey, outlining the evolution of the laser over the past five decades. This includes, amongst other aspects, gas lasers, excimer lasers, the wide range of solid-state and semiconductor lasers, and femtosecond and other pulsed lasers where particular attention is paid to high-power sources. Subsequent chapters address related topics such as laser modulation and nonlinear frequency conversion. In closing, the enormous importance of the laser is demonstrated by highlighting its current applications in everyday life and its potential for future developments. Typical applications in advanced material processing, medicine and biophotonics as well as plasma and X-ray generation for nanoscale lithography are discussed. The book provides broad and topical coverage of laser photonics and opto-electronics, focusing on significant findings and recent advances rather than in-depth theoretical studies. Thus, it is intended not only for university students and engineers, but also for scientists and professionals applying lasers in biomedicine, material processing and everyday consumer products. Further, it represents essential reading for engineers using or developing high-power lasers for scientific or industrial applications.
This book brings together more closely researchers working in the two fields of quantum optics and nano-optics and provides a general overview of the main topics of interest in applied and fundamental research. The contributions cover, for example, single-photon emitters and emitters of entangled photon pairs based on epitaxially grown semiconductor quantum dots, nitrogen vacancy centers in diamond as single-photon emitters, coupled quantum bits based on trapped ions, integrated waveguide superconducting nanowire single-photon detectors, quantum nano-plasmonics, nanosensing, quantum aspects of biophotonics and quantum metamaterials. The articles span the bridge from pedagogical introductions on the fundamental principles to the current state-of-the-art, and are authored by pioneers and leaders in the field. Numerical simulations are presented as a powerful tool to gain insight into the physical behavior of nanophotonic systems and provide a critical complement to experimental investigations and design of devices.
|Release Date||: 2008|
|Pages||: 329 pages|