biopharmaceutics and pharmacokinetics considerations

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Biopharmaceutics and Pharmacokinetics Considerations
Author : N.A
Publisher : Academic Press
Release Date : 2021-07-15
ISBN 10 : 9780128144251
Pages : 575 pages
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Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology

Applied Biopharmaceutics and Pharmacokinetics
Author : Leon Shargel,Andrew B. C. Yu
Publisher : McGraw-Hill/Appleton & Lange
Release Date : 1993
ISBN 10 :
Pages : 625 pages
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The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Biopharmaceutics Applications in Drug Development
Author : Rajesh Krishna,Lawrence Yu
Publisher : Springer Science & Business Media
Release Date : 2007-09-20
ISBN 10 : 038772379X
Pages : 396 pages
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The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Applied Biopharmaceutics and Pharmacokinetics
Author : Leon Shargel,Andrew B. C. Yu
Publisher : McGraw-Hill/Appleton & Lange
Release Date : 1993
ISBN 10 :
Pages : 625 pages
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The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Applications of Pharmacokinetic Principles in Drug Development
Author : Rajesh Krishna
Publisher : Springer Science & Business Media
Release Date : 2004
ISBN 10 : 9780306477669
Pages : 550 pages
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This book presents a collection of articles that represent individual and expert perspectives in both preclinical and clinical development, including case studies on real-life examples of successful drugs that add value to the pharmacokinetic principles learned and applied. Unlike existing books that focus on pharmacokinetic theory, the current book emphasizes application of pharmacokinetic principles in new drug development.

Applied Biopharmaceutics & Pharmacokinetics
Author : Leon Shargel,Andrew B. C. Yu
Publisher : McGraw-Hill/Appleton & Lange
Release Date : 1999
ISBN 10 :
Pages : 768 pages
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This new edition emphasizes the application and understanding of basic theoretical principles of biopharmaceutics and pharmacokinetics. Now with a second highlight color, this book helps students gain skills in problem solving and includes examples and practice problems and solutions.

Biopharmaceutics and clinical pharmacokinetics : an introduction
Author : Robert E. Notari
Publisher : N.A
Release Date : 1977
ISBN 10 :
Pages : 416 pages
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Dosage Form Design Considerations
Author : N.A
Publisher : Academic Press
Release Date : 2018-07-28
ISBN 10 : 0128144246
Pages : 820 pages
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Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. Examines the history and recent developments in drug dosage forms for pharmaceutical sciences Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Clinical Trials of Drugs and Biopharmaceuticals
Author : Chi-Jen Lee,Lucia H. Lee,Christopher L. Wu,Benjamin R. Lee,Mei-Ling Chen
Publisher : CRC Press
Release Date : 2005-09-19
ISBN 10 : 9781420039146
Pages : 520 pages
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The pharmaceutical industry is on the verge of an exciting and challenging century. Advances in pharmaceutical sciences have dramatically changed the processes of discovery and development of new therapeutic drugs and, in turn, resulted in an extraordinary increase in the potential prophylactic and therapeutic interventions. In this atmosphere, an

Developing Solid Oral Dosage Forms
Author : Yihong Qiu,Yisheng Chen,Geoff G.Z. Zhang,Lirong Liu,William Porter
Publisher : Academic Press
Release Date : 2009-03-10
ISBN 10 : 9780080932729
Pages : 978 pages
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Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies

ADME Processes in Pharmaceutical Sciences
Author : Alan Talevi,Pablo A. M. Quiroga
Publisher : Springer
Release Date : 2018-11-30
ISBN 10 : 3319995936
Pages : 362 pages
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Absorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. As an introduction oriented to pharmacy students, it is also written for scientist from different fields outside of pharmaceutics. (e.g. material scientist, material engineers, medicinal chemists) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and some biological background. Pedagogical features such as objectives, keywords, discussion questions, summaries and case studies add valuable teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters, multi-drug resistance related to pharmacokinetic phenomena, last generation pharmaceutical carriers (nanopharmaceuticals), in vitro and in vivo bioequivalence studies, biopharmaceuticals, pharmacogenomics, drug-drug and food-drug interactions, and in silico and in vitro prediction of ADME properties. In comparison with other similar textbooks, around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume, and was written with leading experts on the correspondent topic, including scientists and academics from USA and UK (Duquesne University School of Pharmacy, Indiana University School of Medicine, University of Utah College of Pharmacy, University of Maryland, University of Bath). Additionally, each of the initial chapters dealing with the generalities of drug absorption, distribution, metabolism and excretion would include relevant, classic examples related to each topic with appropriate illustrations (e.g. importance of active absorption of levodopa, implications in levodopa administration, drug drug interactions and food drug interactions emerging from the active uptake; intoxication with paracetamol as a result of glutathione depletion, CYP induction and its relationship with acute liver failure caused by paracetamol, etc). ADME Processes and Pharmaceutical Sciences is written as a core textbook for ADME processes, pharmacy, pharmacokinetics, drug delivery, biopharmaceutics, drug disposition, drug design and medicinal chemistry courses.

Biopharmaceutics and Clinical Pharmacokinetics
Author : Milo Gibaldi
Publisher : Lippincott Williams & Wilkins
Release Date : 1991
ISBN 10 :
Pages : 406 pages
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This updated introduction to the clinical applications of pharmacokinetics looks at gastrointestinal absorption, prolonged release medication, and drug disposition. The effects of disease, weight, age, sex and genetic factors on pharmacokinetic variability and drug response are detailed. Bioequivalence and regulatory considerations for generic drug.