biomimetic biomaterials

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Biomimetic Biomaterials
Author : Andrew J Ruys
Publisher : Elsevier
Release Date : 2013-09-30
ISBN 10 : 0857098888
Pages : 344 pages
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A significant proportion of modern medical technology has been developed through biomimetics, which is biologically inspired by studying pre-existing functioning systems in nature. Typical biomimetically inspired biomaterials include nano-biomaterials, smart biomaterials, hybrid biomaterials, nano-biocomposites, hierarchically porous biomaterials and tissue scaffolds. This important book summarises key research in this important field. The book is divided into two parts: Part one is devoted to the biomimetics of biomaterials themselves while part two provides overviews and case studies of tissue engineering applications from a biomimetics' perspective. The book has a strong focus on cutting edge biomimetically inspired biomaterials including chitin, hydrogels, calcium phosphates, biopolymers and anti-thrombotic coatings. Since many scaffolds for skin tissue engineering are biomimetically inspired, the book also has a strong focus on the biomimetics of tissue engineering in the repair of bone, skin, cartilage, soft tissue and specific organs. With its distinguished editor and international team of contributors, Biomimetic biomaterials is a standard reference for both the biomaterials research community and clinicians involved in such areas as bone regeneration, skin tissue and wound repair. Places strong focus on cutting edge biomimetically-inspired biomaterials including chitin, hydrogels, calcium phosphates, biopolymers and anti-thrombotic coatings Provides overviews and case studies of tissue engineering applications from a biomimetics perspective Also places focus on the biomimetics of tissue engineering in the repair of bone, skin, cartilage, soft tissue and specific organs

Biomimetic biomaterials
Author : S. Sprio,M. Sandri,M. Iafisco,S. Panseri,C. Cunha,A. Ruffini,N. Zini,R. Toni,A. Tampieri
Publisher : Elsevier Inc. Chapters
Release Date : 2013-09-30
ISBN 10 : 0128088087
Pages : 344 pages
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Scientific research on tissue regeneration is increasingly becoming the most promising response to a number of disabling pathologies with huge impact on the progressively growing and ageing world population. The biomimicry of scaffolds with the target tissue is now universally considered to be a key requirement to properly instruct cells towards the restoration of physiological functioning. In this respect, the present chapter presents an overview of recent findings on biomimetic materials and devices addressed to bone and osteochondral tissues as well as soft organ regeneration. Particular focus is given to new apatite phases, including the newly discovered superparamagnetic apatite and processes to develop ceramic, polymeric and hybrid regenerative scaffolds.

Biomimetic biomaterials
Author : H. Ehrlich
Publisher : Elsevier Inc. Chapters
Release Date : 2013-09-30
ISBN 10 : 0128088095
Pages : 344 pages
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Chitin is an evolutionarily ancient and fundamental template in biomineralization, commonly found in invertebrate species and biological systems across the globe. The chapter first discusses structural peculiarities of chitin from sponges (Porifera) with regards to its role in both calcification and silicification. It then describes strategies for applications of this unique chitin towards biomedical and technical goals.

Biomimetic biomaterials
Author : R. Rabiei,A.K. Dastjerdi,M. Mirkhalaf,F. Barthelat
Publisher : Elsevier Inc. Chapters
Release Date : 2013-09-30
ISBN 10 : 0128088109
Pages : 344 pages
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This chapter investigates the concept of hierarchy widely found in biological materials. First, natural hierarchical materials are explored in terms of their high order structures formed from universal building blocks. Hierarchical arrangement is claimed to give rise to remarkable mechanical properties of biological structures. Therefore at the next step, the significance of hierarchical structuring on mechanical properties is investigated through available analytical models. Finally, fabrication methods which could potentially lead to artificial hierarchical structures are briefly reviewed in the domain of biomimetics.

Biomimetic biomaterials
Author : P. Boughton,G. Roger,R. Rohanizadeh,R.S. Mason,A. Ruys
Publisher : Elsevier Inc. Chapters
Release Date : 2013-09-30
ISBN 10 : 0128088125
Pages : 344 pages
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Naturally occurring gradients have been identified in the natural spinal disk joint. Emulating these gradients within a total joint arthroplasty may allow the motion-moderating function of the disk to be more closely replicated. Biomimetic functionally gradient materials have been developed for providing rigid bone-engaging caudal and coronal bioactive surfaces that transition to a flexible fibrocartilage-like portion. Methods are detailed for forming thermoplastic elastomers, bioactive reinforcement, radially aligned anisotropic composites and functionally graded materials with axial and radial gradients. Employing these methods to the vertebral-interlocking spinal disk design provides a biomimetic approach to reduce risk of hypermobility, stress concentration and implant migration.

Biomimetic biomaterials
Author : D. Campbell
Publisher : Elsevier Inc. Chapters
Release Date : 2013-09-30
ISBN 10 : 0128088176
Pages : 344 pages
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This chapter discusses recent developments of injectable biomimetic hydrogel systems found in soft tissue repair applications. It begins by introducing how biomimesis and biomaterials are related, and how tissue repair systems can be considered biomimetic. We introduce hydrogels by discussing their classification, synthesis and applications, then discuss how injectable biomimetic hydrogels have been investigated for use in soft tissue repair. Different approaches to the use of biomimetic hydrogels for soft tissue repair are covered, focusing on synthetic, non-biodegrable polymers. We include so-called conventional polymers and more biomimetic polymers. The chapter concludes with the likely future trends and highlights further reading materials.

Biomimetic biomaterials
Author : E. Mázl Chánová,F. Rypáček
Publisher : Elsevier Inc. Chapters
Release Date : 2013-09-30
ISBN 10 : 0128088117
Pages : 344 pages
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This chapter outlines the role of surface modifications for biomaterials used in tissue engineering, and reviews approaches to creating biomimetic coatings on several types of biomaterial. In the first section, the principles used in preparing non-fouling surfaces with minimized non-specific interactions with proteins are discussed, followed by the creation of biomimetic structures which promote controlled cell-surface interactions. The following sections go on to provide examples of key methods used in relation to specific materials, including polymers, metals and ceramics. Finally, methods for the characterization of coating efficiency are reviewed.

Biomimetic Materials And Design
Author : Angela Dillow,Anthony Lowman
Publisher : CRC Press
Release Date : 2002-08-28
ISBN 10 : 9780203908976
Pages : 696 pages
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Detailing techniques in wound healing and reconstruction, this reference describes the mechanisms and architecture of biological systems to formulate and design natural and synthetic compounds, degradable and non-degradable scaffolds, and targeted drug delivery devices. It offers strategies to control adhesive interactions, elicit specific cellular responses, and improve the biocompatibility, performance, and durability of prosthetic materials. Covering advances in the field, the book discusses the effect of topographical features on cell behaviors such as orientation, adhesion, migration, proliferation, and differentation.

Biomimetic, Bioresponsive, and Bioactive Materials
Author : Matteo Santin,Gary J. Phillips
Publisher : John Wiley & Sons
Release Date : 2012-04-10
ISBN 10 : 0470056711
Pages : 248 pages
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The accessible introduction to biomaterials and their applications in tissue replacement, medical devices, and more Molecular and cell biology is being increasingly integrated into the search for high-performance biomaterials and biomedical devices, transforming a formerly engineering- and materials science–based field into a truly interdisciplinary area of investigation. Biomimetic, Bioresponsive, and Bioactive Materials presents a comprehensive introduction to biomaterials, discussing how they are selected, designed, and modified for integration with living tissue and how they can be utilized in the development of medical devices, orthopedics, and other related areas. Examining the physico chemical properties of widely used biomaterials and their uses in different clinical fields, the book explores applications including soft and hard tissue replacement; biointeractive metals, polymers, and ceramics; and in vitro, in vivo, and ex vivo biocompatibility tests and clinical trials. The book critically assesses the clinical level of research in the field, not only presenting proven research, but also positing new avenues of exploration. Biomimetic, Bioresponsive, and Bioactive Materials contains everything needed to get a firm grasp on materials science, fast. Written in an accessible style and including practice questions that test comprehension of the material covered in each chapter, the book is an invaluable tool for students as well as professionals new to the field.

Journal of Biomimetics, Biomaterials & Tissue Engineering
Author : Trans Tech Publications, Limited
Publisher : Trans Tech Publications Ltd
Release Date : 2012-10-08
ISBN 10 : 3038268348
Pages : 104 pages
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This volume of the "Journal of Biomimetics, Biomaterials and Biomedical Engineering" covers topical issue of biomimetic approach to the development of modern means of a wide range of industrial applications, the new solutions in the field of biomedical engineering and of pharmacological practice and also illuminates the results of the latest solutions in the field of development of biomaterials and their application.

Journal of Biomimetics, Biomaterials and Biomedical Engineering
Author : Trans Tech Publications, Limited
Publisher : Trans Tech Publications Ltd
Release Date : 2014-06-06
ISBN 10 : 3038268399
Pages : 96 pages
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This volume of the "Journal of Biomimetics, Biomaterials and Biomedical Engineering" covers topical issue of biomimetic approach to the development of modern means of a wide range of industrial applications, the new solutions in the field of biomedical engineering and of pharmacological practice and also illuminates the results of the latest solutions in the field of development of biomaterials and their application.

Biomimetic Approaches for Biomaterials Development
Author : Joao F. Mano
Publisher : John Wiley & Sons
Release Date : 2013-02-11
ISBN 10 : 3527652302
Pages : 606 pages
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Biomimetics, in general terms, aims at understanding biological principles and applying them for the development of man-made tools and technologies. This approach is particularly important for the purposeful design of passive as well as functional biomaterials that mimic physicochemical, mechanical and biological properties of natural materials, making them suitable, for example, for biomedical devices or as scaffolds for tissue regeneration. The book comprehensively covers biomimetic approaches to the development of biomaterials, including: an overview of naturally occurring or nature inspired biomaterials; an in-depth treatment of the surface aspects pivotal for the functionality; synthesis and self-assembly methods to prepare devices to be used in mineralized tissues such as bone and teeth; and preparation of biomaterials for the controlled/ sustained release of bioactive agents. The last part reviews the applications of bioinspired materials and principles of design in regenerative medicine such as in-situ grown bone or cartilage as well as the biomimetic techniques for soft tissue engineering. The comprehensive scope of this book makes it a must-have addition to the bookshelf of everyone in the fields of Materials Science/Engineering, Nanotechnologies / Nanosciences, Medical Sciences, Biochemistry, Polymer Chemistry, and Biomedical Engineering.