This volume, Bioresponsive Polymers: Design and Application in Drug Delivery, focuses on recent advancements in bioresponsive polymers and their design, characterization, and applications in varied fields, such as drug delivery and gene delivery. It looks at several carriers for drug delivery and biological molecules using different bioresponsive polymers. To address the many difficulties in existing dosage forms, this book provides information on recent developments to overcome drawbacks of conventional forms of the drug delivery. The chapters cover most areas of bioresponsive polymers, starting with a basic introduction to bioresponsive polymers, followed by chapters on design, characterization, and mechanism of bioresponsive polymers; and applications of drug and gene delivery using bioresponsive polymers via oral, topical, nasal, ocular, and parenteral methods. The book also reviews recent advancements in bioresponsive polymers and advanced applications, such as engineering particulate moieties, biomedical applications, hydrogels as emerging therapy, and electrochemical responses, bioresponsive nanoparticles, and bioresponsive hydrogels.
This book summarizes the recent advances in the science and engineering of polymer-gel-based materials in different fields. It also discusses the extensive research developments for the next generation of smart materials. It takes an in-depth look at the current perspectives and market opportunities while pointing to new possibilities and applications. The book addresses important topics such as stimuli responsive polymeric nanoparticles for cancer therapy; polymer gel containing metallic materials; chemotherapeutic applications in oncology; conducting polymer-based gels and their applications in biological sensors; imprinted polymeric gels for pharmaceutical and biomedical purposes; applications of biopolymeric gels in the agricultural sector; application of polymer gels and their nanocomposites in electrochemistry; smart polyelectrolyte gels as a platform for biomedical applications; agro-based polymer gels and their application in purification of industrial water wastes; polymer gel composites for bio-applications. It will be of interest to researchers working in both industry and academia.
|Author||: Masoud Mozafari,Narendra Pal Singh Chauhan|
|Release Date||: 2019-06-14|
|ISBN 10||: 0128166045|
|Pages||: 430 pages|
Advanced Functional Polymers for Biomedical Applications presents novel techniques for the preparation and characterization of functionalized polymers, enabling researchers, scientists and engineers to understand and utilize their enhanced functionality in a range of cutting-edge biomedical applications. Provides systematic coverage of the major types of functional polymers, discussing their properties, preparation techniques and potential applications Presents new synthetic approaches alongside the very latest polymer processing and characterization methods Unlocks the potential of functional polymers to support ground-breaking techniques for drug and gene delivery, diagnostics, tissue engineering and regenerative medicine
Functionalized polymers are macromolecules to which chemically bound functional groups are attached which can be used as catalysts, reagents, protective groups, etc. Functionalized polymers have low cost, ease of processing and attractive features for functional organic molecules. Chemical reactions for the introduction of functional groups in polymers and the conversion of functional groups in polymers depend on different properties. Such properties are of great importance for functionalization reactions for possible applications of reactive polymers. This book deals with the synthesis and design of various functional polymers, the modification of preformed polymer backbones and their various applications.
This book exclusively focuses on the science and fundamentals of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the core science and fundamentals of both synthetic and natural polymer-based gels, and pays particular attention to applications in the various research fields of biomedicine and engineering. Key topics addressed include: polysaccharide-based gels and their fundamentals; stimuli-responsive polymer gels; polymer gels applied to enzyme and cell immobilization; chitosan-based gels for cancer therapy; natural polymeric and gelling agents; radiation dosimetry; polymeric gels as vehicles for enhanced drug delivery across the skin; transport in and through gel; and polymer gel nanocomposites and functional gels. The book’s extensive and highly topical coverage will appeal to researchers working in a broad range of fields in industry and academia alike.
|Author||: Sutapa Biswas Majee|
|Publisher||: BoD – Books on Demand|
|Release Date||: 2016-08-24|
|ISBN 10||: 9535125095|
|Pages||: 266 pages|
This book is an Up-to-date and authoritative account on physicochemical principles, pharmaceutical and biomedical applications of hydrogels. It consists of eight contributions from different authors highlighting properties and synthesis of hydrogels, their characterization by various instrumental methods of analysis, comprehensive review on stimuli-responsive hydrogels and their diverse applications, and a special section on self-healing hydrogels. Thus, this book will equip academia and industry with adequate basic and applied principles related to hydrogels.
This reference/text addresses concepts and synthetic techniques for the preparation of polymers for state-of-the-art use in biomedicine, synthetic biology, and bionanotechnology.
Polypeptide-Polymer Conjugates, by Henning Menzel Chemical Strategies for the Synthesis of Protein-Polymer Conjugates, by Björn Jung and Patrick Theato Glycopolymer Conjugates, by Ahmed M. Eissa and Neil R. Cameron DNA-Polymer Conjugates: From Synthesis, Through Complex Formation and Self-assembly to Applications, by Dawid Kedracki, Ilyès Safir, Nidhi Gour, Kien Xuan Ngo and Corinne Vebert-Nardin Synthesis of Terpene-Based Polymers, by Junpeng Zhao and Helmut Schlaad
This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
This book provides a general introduction to nanogels, and designs of various stimuli-sensitive nanogels that are able to control drug release in response to specific stimuli. Nanogels are three-dimensional nanosized networks that formed by physically or chemically crosslinking polymers. They have highly interesting properties such as biocompatibility, high stability, particle size adjustment, drug loading capability and modification of the surface for active targeting. They can respond to stimuli which results in the controlled release of drug and targeting of the site.
Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.
Science of the stimuli-responsive materials, and in particular polymers and coatings will play a key role in the developments of future technologies and new knowledge in this field. The book provides the highlights for newcomes as well as a comprehensive review for experienced practitioners of recent advances to stimuli-responsive polymeric films and coatings. Two sections of the book focus on synthetic and physocao-chemical aspects and this book is a must to those involved in the growing field of nanotechnologies of stimuli-responsive polymers.