Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology
A Certain Kind of Wisdom In Plato’s Apology, the Greek philosopher Socrates is on trial to defend himself against the allegation of corrupting the youth of Athens. Socrates denies this charge and offers an alternate reason for why he is on trial. He explains, “[w]hat has caused my reputation is none other than a certain kind of wisdom. What kind of wisdom? Human wisdom, perhaps(1). ” He proceeds to tell the story of his friend Chaerophon, who once asked the Oracle at Delphi whether there was anyone wiser than Socrates. The Oracle answered that there was not. Socrates did not agree and thought that he would try to prove the Oracle wrong. And so he set about seeking out Athenians with a reputation for wisdom in various regards in order to test their claims to knowledge through questioning. He discovered many with false claims to knowledge and none with genuine wisdom and ultimately concluded that he was the wisest. He reached this conclusion not because of any special knowledge he possessed that others did not, but rather because he recognized his own lack of knowledge and strived to learn more, while others thought that they were kno- edgeable but were not. Socrates’ conclusion that there is wisdom in recognizing the limitations of accepted knowledge represents the motivation for this book.
Includes fold-out companion website information guide.
|Author||: Robert C. Elston,William Johnson|
|Publisher||: John Wiley & Sons|
|Release Date||: 2008-11-20|
|ISBN 10||: 0470024917|
|Pages||: 384 pages|
Anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. This book, a revised new edition of the successful Essentials of Biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. Unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures. This Book: Surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares. Introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research. Is illustrated throughout with simple examples to clarify the statistical methodology. Explains Bayes’ theorem pictorially. Features exercises, with answers to alternate questions, enabling use as a course text. Written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. Graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.
This text is an easy-to-understand, application-oriented guidebook for learning the basic principles of epidemiologic investigation. Numerous opportunities are presented to apply and test learning through problems and application exercises. Answers are provided.
This book provides not only the theory of biostatistics, but also the opportunity of applying it in practice. In fact, each chapter presents one or more specific examples on how to perform an epidemiological or statistical data analysis and includes download access to the software and databases, giving the reader the possibility of replicating the analyses described.
Basic Statistics and Epidemiology is a straightforward primer in basic statistics that emphasizes its practical use in epidemiology and public health, providing an understanding of essential topics such as study design, data analysis and statistical methods used in the execution of medical research. Assuming no prior knowledge, the clarity of the text and care of presentation ensure those new to, or challenged by, these topics are given a thorough introduction without being overwhelmed by unnecessary detail. An understanding and appreciation of statistics is central to ensuring that professional practice is based on the best available evidence, in order to treat and help most appropriately the wider community. By reading this book, students, researchers, doctors, nurses and health managers will have the knowledge necessary to understand and apply the tools of statistics and epidemiology to their own practice.
Basic epidemiology provides an introduction to the core principles and methods of epidemiology, with a special emphasis on public health applications in developing countries. This edition includes chapters on the nature and uses of epidemiology; the epidemiological approach to defining and measuring the occurrence of health-related states in populations; the strengths and limitations of epidemiological study designs; and the role of epidemiology in evaluating the effectiveness and efficiency of health care. The book has a particular emphasis on modifiable environmental factors and encourages the application of epidemiology to the prevention of disease and the promotion of health, including environmental and occupational health.
Each disease section includes: disease name, description of the clinical features of the disease, infectious agent, occurrence, disease reservoir, mode of transmission, incubation period, period of communicability, susceptibility and resistance, and methods of control.
Biostatistics and Epidemiology/A Primer for Health Professionals offers practical guidelines and gives a concise framework for research and interpretation in the field. In addition to major sections covering statistics and epidemiology, the book includes a comprehensive exploration of scientific methodology, probability, and the clinical trial. The principles and methods described in this book are basic and apply to all medical subspecialties, psychology and education. The primer will be especially useful to public health officials and students looking for an understandable treatment of the subject.
Here is a book for clinicians, clinical investigators, trainees, and graduates who wish to develop their proficiency in the planning, execution, and interpretation of clinical and epidemiological research. Emphasis is placed on the design and analysis of research studies involving human subjects where the primary interest concerns principles of analytic (cause-and- effect) inference. The topic is presented from the standpoint of the clinician and assumes no previous knowledge of epidemiology, research design or statistics. Extensive use is made of illustrative examples from a variety of clinical specialties and subspecialties. The book is divided into three parts. Part I deals with epidemiological research design and analytic inference, including such issues as measurement, rates, analytic bias, and the main forms of observational and experimental epidemiological studies. Part II presents the principles and applications of biostatistics, with emphasis on statistical inference. Part III comprises four chapters covering such topics as diagnostic tests, decision analysis, survival (life-table) analysis, and causality.
This book contains a Foreword by Allyson Pollock, Professor and Head, Centre for International Public Health Policy, University of Edinburgh. Healthcare students, practitioners and researchers need a sound basis for making valid statistical inferences from health data. To make the best use of statistical software, it is necessary to understand how probabilistic inference works. This book explains that, along with the various ways statistical data can be described and presented. It is designed to develop insight rather than simply the mechanical skills found in other textbooks. This book is specifically designed to underpin the concepts of statistics and epidemiology. It is practical and easy to use and is ideal for people who can feel uncomfortable with mathematics. 'Excellent. A great primer for all students and research workers engaged in learning how to use statistical ideas in public health. It sets out the core concepts and explains them clearly, using worked examples as illustration. If followed carefully, the engaged reader should be able to use the standard statistical software packages intelligently and sensitively. It will stimulate the public health student, in whatever context, and new researchers, to approach the enterprise with enhanced confidence in interpreting and coherently explaining their findings.' - Allyson Pollock, in the Foreword.
|Author||: Julien I. E. Hoffman|
|Publisher||: Academic Press|
|Release Date||: 2015-09-03|
|ISBN 10||: 0128026073|
|Pages||: 770 pages|
Biostatistics for Practitioners: An Interpretative Guide for Medicine and Biology deals with several aspects of statistics that are indispensable for researchers and students across the biomedical sciences. The book features a step-by-step approach, focusing on standard statistical tests, as well as discussions of the most common errors. The book is based on the author’s 40+ years of teaching statistics to medical fellows and biomedical researchers across a wide range of fields. Discusses how to use the standard statistical tests in the biomedical field, as well as how to make statistical inferences (t test, ANOVA, regression etc.) Includes non-standards tests, including equivalence or non-inferiority testing, extreme value statistics, cross-over tests, and simple time series procedures such as the runs test and Cusums Introduces procedures such as multiple regression, Poisson regression, meta-analysis and resampling statistics, and provides references for further studies
|Author||: James F. Jekel,Joann G. Elmore,David L. Katz|
|Publisher||: Saunders Limited.|
|Release Date||: 1996-01-01|
|ISBN 10||: 9780721652580|
|Pages||: 297 pages|
This text focuses on the specific knowledge in this field needed by medical students for their course work and for the USMLE Step I exam. It includes 10-12 questions in each chapter using the same format as the USMLE Step I exam, followed by explanations of the answers. With a clinical focus and real-life medical examples, this exam guide includes chapters on: the US public health system, health promotion and disease prevention goals for the year 2000, and the strengths and weaknesses of the US medical care system.
|Author||: Bertram K.C. Chan, PhD|
|Publisher||: Springer Publishing Company|
|Release Date||: 2015-11-05|
|ISBN 10||: 0826110266|
|Pages||: 500 pages|
Since it first appeared in 1996, the open-source programming language R has become increasingly popular as an environment for statistical analysis and graphical output. This is the first textbook to present classical biostatistical analysis for epidemiology and related public health sciences to students using the R language. Based on the assumption that readers have minimal familiarity with statistical concepts, the author uses a step-by-step approach to building skills. The text encompasses biostatistics from basic descriptive and quantitative statistics to survival analysis and missing data analysis in epidemiology. Illustrative examples, including real-life research problems drawn from such areas as nutrition, environmental health, and behavioral health, engage students and reinforce the understanding of R. These examples illustrate the replication of R for biostatistical calculations and graphical display of results. The text covers both essential and advanced techniques and applications in biostatistics that are relevant to epidemiology. Also included are an instructor's guide, student solutions manual, and downloadable data sets. Key Features: First overview biostatistics textbook for epidemiology and public health that uses the open-source R program Covers essential and advanced techniques and applications in biostatistics as relevant to epidemiology Features abundant examples to illustrate the application of R language for biostatistical calculations and graphical displays of results Includes instructor's guide, student solutions manual, and downloadable data sets.
Basic Biostatistics is a concise, introductory text that covers biostatistical principles and focuses on the common types of data encountered in public health and biomedical fields. The text puts equal emphasis on exploratory and confirmatory statistical methods. Sampling, exploratory data analysis, estimation, hypothesis testing, and power and precision are covered through detailed, illustrative examples. The book is organized into three parts: Part I addresses basic concepts and techniques; Part II covers analytic techniques for quantitative response variables; and Part III covers techniques for categorical responses. The Second Edition offers many new exercises as well as an all new chapter on "Poisson Random Variables and the Analysis of Rates." With language, examples, and exercises that are accessible to students with modest mathematical backgrounds, this is the perfect introductory biostatistics text for undergraduates and graduates in various fields of public health. Features: Illustrative, relevant examples and exercises incorporated throughout the book. Answers to odd-numbered exercises provided in the back of the book. (Instructors may requests answers to even-numbered exercises from the publisher. Chapters are intentionally brief and limited in scope to allow for flexibility in the order of coverage. Equal attention is given to manual calculations as well as the use of statistical software such as StaTable, SPSS, and WinPepi. Comprehensive Companion Website with Student and Instructor's Resources.
Based on Kahn's An Introduction to Epidemiological Methods (Oxford, 1983), this book contains a wealth of new material, including a substantially expanded discussion of the statistical concepts and methods fundamental to epidemiology.
This workbook is designed to teach the major fundamental concepts in Epidemiology, Biostatistics, and clinical research design alongside the textbook "Epidemiology and Biostatistics, 2nd Edition". It is written in concise and organized fashion with many examples to illustrate the concepts deriving from a collection of written materials created to teach Epidemiology and Biostatistics to medical students. The major differences from related titles include a “story” based approach toward teaching the material, relative brevity while maintaining focus on key concepts, and taking the perspective of first-time learners (avoiding and/or clearly defining jargon, using clear common-sense language). It features a variety of questions: long, short, and multiple choice questions. The workbook is made to provide students with the tools necessary to form their own informed conclusions from the clinical research literature.
Get a quick, expert overview of the many key facets of heart failure research with this concise, practical resource by Dr. Longjian Liu. This easy-to-read reference focuses on the incidence, distribution, and possible control of this significant clinical and public health problem which is often associated with higher mortality and morbidity, as well as increased healthcare expenditures. This practical resource brings you up to date with what’s new in the field and how it can benefit your patients. Features a wealth of information on epidemiology and research methods related to heart failure. Discusses pathophysiology and risk profile of heart failure, research and design, biostatistical basis of inference in heart failure study, advanced biostatistics and epidemiology applied in heart failure study, and precision medicine and areas of future research. Consolidates today’s available information and guidance in this timely area into one convenient resource.