approaches to the purification analysis and characterization of antibody based therapeutics

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Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics
Author : Allan Matte
Publisher : Elsevier
Release Date : 2020-09-07
ISBN 10 : 0081030193
Pages : 222 pages
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Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book. Covers the vital new area of R&D on therapeutic antibodies Written by leading scientists and researchers Up-to-date coverage and includes a detailed bibliography

Process Scale Purification of Antibodies
Author : Uwe Gottschalk
Publisher : John Wiley & Sons
Release Date : 2017-04-03
ISBN 10 : 1119126916
Pages : 752 pages
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Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing

Science
Author : John Michels
Publisher : N.A
Release Date : 2001-09
ISBN 10 :
Pages : 329 pages
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Monoclonal Antibodies
Author : Philip Shepherd,Christopher J. Dean
Publisher : Practical Approach (Paperback)
Release Date : 2000
ISBN 10 : 9780199637225
Pages : 479 pages
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Monoclonal Antibodies: A Practical Approach covers the preparation, testing, derivation, and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described, making the book of interest to established and inexperienced immunologists. Both the standard somatic hybridization technique and recombinant techniques, including the use of phage libraries, for the preparation of rodent and human monoclonal antibodies are described. Protocols for both the small and large scale production are detailed, as well as purification and labelling (with both radioisotopes and non-radioisotopes) methods. The applications of monoclonal antibodies in immunoblotting, enzyme linked immunoassays, immunofluorescence, and FACS analysis are all covered in detail. Finally protocols are given for the use of monoclonal antibodies in rheumatoid arthritis, tissue typing, detecting DNA modified during chemotherapy, and in the clinical analysis of transplantation samples for malignancy. This book will therefore be an invaluable laboratory companion to anyone using monoclonal antibodies in their research.

Purification and Analysis of Recombinant Proteins
Author : SEETHARAM
Publisher : CRC Press
Release Date : 1991-01-07
ISBN 10 : 9780824782771
Pages : 344 pages
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Covering both new and traditional topics in the purification and analysis of recombinant proteins, this volume demonstrates how to overcome problems in protein research and presents practical methods used in protein work, explaining their theoretical bases. The collection also explores innovative co

Index Medicus
Author : N.A
Publisher : N.A
Release Date : 2003
ISBN 10 :
Pages : 329 pages
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Research Awards Index
Author : N.A
Publisher : N.A
Release Date : 1977
ISBN 10 :
Pages : 329 pages
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Cumulated Index Medicus
Author : N.A
Publisher : N.A
Release Date : 1997
ISBN 10 :
Pages : 329 pages
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Therapeutic Monoclonal Antibodies
Author : Zhiqiang An
Publisher : John Wiley & Sons
Release Date : 2011-09-20
ISBN 10 : 1118210263
Pages : 896 pages
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70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. First book to address the discovery and development of antibody therapeutics in their entirety. Most chapters contain experimental data to illustrate the principles described in them. Authors provide detailed methodologies that readers can take away with them and use in their own laboratories.

Cancer Immunology: Innovative Approaches to Therapy
Author : Ronald B. Herberman
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
ISBN 10 : 146132629X
Pages : 230 pages
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This volume is the second in the 'Cancer Treatment and Research' series focussing on basic and clinical tumor immunology. It has a rather different focus or emphasis from that of the first volume, published two years ago. That work (Basic and Clinical Tumor Immunology, R.B. Herberman, ed., Martinus Nijhoff Publishers, 1983) devoted considerable attention to up dated summaries in various areas of classical tumor immunology: specific antitumor immunity, the immunologic competence of cancer patietns, char acterization of human tumor-associated antigens, the ability to propagate specifically immune T cells in culture in the presence of interleukin 2, and the use of such cells for adoptive immunotherapy of established tumors. of evidence concerning the immune However, it also reviewed the status surveillance hypothesis and pointed out the need to consider non-T cell mediated mechanisms of host resistance. In particular, one chapter sum marized information on the role of macrophages in host resistance against tumors. The present volume continues to emphasize one of the major themes of the first volume, innovative approaches to the therapy of cancer. It involves contributions from leading investigators on several primary types of therapeutic interventions related to monoclonal antibodies, the col laboration of monoclonal antibodies with macro phages to mediate antibody dependent cellular cytotoxicity, lymphokines, tumor vaccines, and natural killer cells. It also has an up-to-date summary of the immunologic aspects of the exciting and promising work being performed on human T cell leukemia virus in the laboratory of Dr. Robert Gallo.

Federation Proceedings
Author : Federation of American Societies for Experimental Biology
Publisher : N.A
Release Date : 1987
ISBN 10 :
Pages : 329 pages
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Vols. for 1942- include proceedings of the American Physiological Society.

Therapeutic Proteins
Author : Vladimir Voynov,Justin A. Caravella
Publisher : Humana Press
Release Date : 2016-05-01
ISBN 10 : 9781493959495
Pages : 516 pages
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Emphasizing the newest developments in the field, this volume presents detailed methodswith added emphasison therapeutic protein discovery. It features key tips and valuable implementation advice to ensure successful results."