antivenom handbook for snakebite envenomation

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A Clinician's Guide to Australian Venomous Bites and Stings
Author : Julian White
Publisher : N.A
Release Date : 2013
ISBN 10 : 9780646579986
Pages : 330 pages
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Handbook of Venoms and Toxins of Reptiles
Author : Stephen P. Mackessy
Publisher : CRC Press
Release Date : 2016-04-19
ISBN 10 : 9781420008661
Pages : 528 pages
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The Handbook of Venoms and Toxins of Reptiles offers "one-stop shopping" to all biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation. This book examines the topic generally, provides an overview of the current taxonomy of these reptiles, explains the similarities and differences in the venom delivery apparatus in different groups of reptiles, reviews state-of-the-art knowledge about specific venom components and their action, and summarizes effects of envenomation and treatment in humans on different continents. Produced by leading toxinologists, biologists, biochemists, and physicians from 12 countries, the book provides a broad, international perspective that bridges divergent areas in modern biology. A synthesis of current knowledge about venoms and venomous reptiles, it contains a wealth of illustrations, including an 8-page color insert, that present a view of reptile toxinology from the whole animal to the glands producing venoms to the molecular models and the mechanisms of actions of the toxins themselves. The book provides a context for understanding the range of activities present in venoms and supplies detailed information on many enzymes and toxins found in them, bringing into focus the worldwide extent of the occurrence and complexity of human envenomations by reptiles. It explores the unique and interesting results produced by collaborations between specialists from very different fields and how they can stimulate new and continued interest in research on venoms and the animals that produce them.

Handbook of Clinical Toxicology of Animal Venoms and Poisons
Author : Julian White,Jurg Meier
Publisher : CRC Press
Release Date : 2017-11-22
ISBN 10 : 1351443143
Pages : 768 pages
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The Handbook of Clinical Toxicology of Animal Venoms is the first concise, one-volume book devoted to this important subject. The editors are internationally recognized authorities in the biology and clinical aspects of venomous and poisonous animals, and the chapter authors are world leaders in their respective fields of toxicology. All aspects of the topic are covered including information on the biology and taxonomy of poisonous animals, their venom or poison, diagnosis, and general treatment principles and specific treatment. The most up-to-date list of available antivenoms is provided. Coverage of venomous and poisonous animals is comprehensive, with thorough discussions on shellfish poisoning, ciguatera, fugu, coelenterates, stingrays, venous fish, blue-ringed octopus, sea-snakes, scorpions, spiders, insects, and gila lizards. Individual chapters focus on snakes and snakebite in Europe, Africa, Asia, Australia, North America, Central America, and South America. Nearly all clinical chapters have been written by clinicians with extensive experience treating the particular type of animal envenoming or poisoning under consideration. No other book brings together such a wealth of information in this field, and no other book provides it in a format useful to clinicians charged with the responsibility of treating envenomed or poisoned patients. The Handbook of Clinical Toxicology of Animal Venoms is an essential addition to all medical libraries, emergency departments, toxicology departments, poison information centers, and invaluable to all professionals working in these fields.

Australia's Dangerous Snakes
Author : Peter Mirtschin,Arne Rasmussen,Scott Weinstein
Publisher : CSIRO PUBLISHING
Release Date : 2017-11-01
ISBN 10 : 0643106758
Pages : 432 pages
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Australia’s venomous snakes are widely viewed as the world’s most deadly and are regarded with cautious curiosity, fascination and, regrettably, fear. Australia’s Dangerous Snakes examines the biology, natural history, venom properties and bite treatment of medically important venomous marine and terrestrial snakes. It contains comprehensive identification profiles for each species, supported by keys and photographs. In addition to their medical importance, the environmental roles of these snakes and the threats that are causing the decline of many of these reptiles are discussed. Drawing on the authors’ experience in the fields of herpetology, toxinology and clinical medicine, this book stimulates respect and admiration and dispels fear of Australia’s fascinating snakes. Australia’s Dangerous Snakes will provide hours of rewarding reading and valuable information for anyone interested in Australia’s unique wildlife and natural history, and will be an essential reference for herpetologists, toxinologists, physicians, zoo personnel and private snake collectors.

“Venomous Bites from Non-Venomous Snakes
Author : Scott A Weinstein,David A. Warrell,Julian White,Daniel E Keyler
Publisher : Elsevier
Release Date : 2011-06-20
ISBN 10 : 0123877555
Pages : 364 pages
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This book is the first significant contribution to thoroughly examine the potential hazards associated with snakes of the former family, Colubridae. This family contained >65% of living snake species (approximately 3,000 taxa) and has recently been split into multiple families. Many of these snakes produce oral secretions that contain toxins and other biologically-active substances. A large variety of these snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-nineteenth century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of snakes belonging to this diverse, artificial family. There is a need for "one-stop shopping" offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. This book is the first synthesis of this information and includes evidence-based risk assessment, hazard rankings and specific recommendations regarding important species, many common in captivity. Fills a gap in the toxinological, medical and herpetological literature by providing a comprehensive review of this entire assemblage of snakes, with particular attention given to their capacity, real or rumored, to cause harm to humans A patient-centered, evidence-based approach is applied to analyzing documented case reports of bites inflicted by approximately 100 species. Clinical management of medically significant bites from non-front-fanged colubroids is methodically reviewed, and specific recommendations are provided

Venomous Reptiles and Their Toxins
Author : Bryan Fry
Publisher : Oxford University Press
Release Date : 2015-05-13
ISBN 10 : 0190297581
Pages : 576 pages
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Venom research and technology has advanced greatly, rapidly transforming our knowledge of reptile venoms. Research advances, like the development of molecular systematics, provide the framework necessary to reconstruct the evolutionary history of glands and fangs. Such research developments have expanded our understanding of venom's evolution and its usefulness in therapeutic development. The results of this punctuated toxin molecular evolutionary expansion include protein neofunctionalization. While these changes may impact antivenom efficacy, this molecular diversity also facilitates their usefulness in the development of novel drug therapies. Venomous Reptiles And Their Toxins brings together the world's leading toxinologists in this comprehensive study of the entire scope of reptile venoms, from clinical effects to evolution to drug design and development. The book contains detailed applied chapters on clinical care of the envenomed patient, ineffective traditional or modern remedies, occupational considerations involved in the maintenance of institutional venomous reptile collections, veterinary care for venomous reptiles and research methods used in venom research. This book also devotes a chapter to each toxin class found in reptile venoms, detailing the full trajectory of research on the peptide or protein in question. These chapters discuss each toxin's respective role in the envenomation process through to how each has been explored for their biomedical potential. This book is a unique resource for anyone working with venomous reptiles.

Therapeutic Guidelines
Author : Toxicology and Wilderness Expert Group
Publisher : N.A
Release Date : 2012
ISBN 10 : 9780980825329
Pages : 321 pages
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Topics covered in this book include toxicology (General approach, toxidromes, paediatric poisoning, individual drugs and other chemicals), toxicology (Snake bite, spider bite, marine envenoming, marine poisoning, tick bite), wilderness medicine (altitude illness, cold-related illness, diving medicine, electrical injury, heat-related illness, near drowning) and intravenous inotrope infusion calculations.

Clinical Toxinology in Asia Pacific and Africa
Author : P. Gopalakrishnakone,M. A. Faiz,Ravindra Fernando,Christeine Ariaranee Gnanathasan,Abdulrazaq Garba Habib,Chen-Chang Yang
Publisher : Springer
Release Date : 2015-03-12
ISBN 10 : 9789400763852
Pages : 636 pages
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Clinical toxinologic conditions are becoming increasingly frequent, more so than is generally recognized. The conditions comprise of clinical aspects such as the diagnosis, management, and prevention of snakebite envenoming, scorpion sting, mushroom toxins, plant toxins, and other natural toxins. Clinical toxinology also deals with the ecology, epidemiology, regional differences, and varieties of fauna accounting for different envenoming manifestations. This handbook includes 30 chapters addressing various topics on clinical toxinology such as the epidemiology and management of snakebites in different Asian and African countries, disability following snakebite, effect of snake venoms on hemostasis, socioeconomic aspects of snakebites, therapeutic application of snake venom, scorpion sting in the Middle East, jellyfish sting, etc. These titles are written by experts currently working in the subspecialty, many of whom have first-hand experience in the relevant research fields. In virtually all the topics, appropriate illustrations are provided to simplify comprehension including tables, figures and pictures. This reference work on Clinical Toxinology in Asia Pacific and Africa, in the Toxinology handbook series, is designed to keep readers abreast with new knowledge and experience in toxinology regionally and globally. Toxinologists, researchers, scientists, and experts in this field from various working areas considered it necessary to collect all the aspects of clinical toxinology in a single, handy handbook. This can be used by medical students, postgraduate students, general practitioners, specialists in internal medicine, critical care physicians, emergency physicians, and anesthetists worldwide.

Toxicology Handbook
Author : Lindsay Murray,Mark Little,Ovidiu Pascu,Kerry Hoggett
Publisher : Elsevier Health Sciences
Release Date : 2015-02-16
ISBN 10 : 0729542246
Pages : 560 pages
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Toxicology Handbook is a practical evidence-based guide on the care of the poisoned patient. This concise text is informed by the latest clinical research and takes a rigorous and structured risk assessment-based approach to decision making in the context of clinical toxicology. It assists the clinician to quickly find information on poisons, toxins, antidotes, envenomings and antivenoms and determine the appropriate treatment for the acutely poisoned patient. Guides clinicians through drug administration and treatmentIncludes 'handy tips' and 'pitfalls'Incorporates drug dosages and administration are based on current pharmacological regulations Content on drug dosage and administration based on the most up-to-date pharmacological regulations on toxicologyGeographical locations of envenomings from snakes, spiders and jellyfish are portrayed on illustrated mapsNew subchapters include Newer oral anticoagulants (NOACs) and Paracetamol: Modified release formulations

Venomous Snakes of the World
Author : Department of the Navy Bureau of Medicine and Surgery
Publisher : Simon and Schuster
Release Date : 2013-09-01
ISBN 10 : 1628734167
Pages : 336 pages
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Originally published in 1962, and fully updated and colorized by Scott Shupe, Poisonous Snakes of the World is the perfect practical guide to not only snake bite survival, but to understand and identifying every venomous snake on the planet. Even if no life hangs in the balance, this manual is a great reference guide for the outdoors enthusiast, the reptile lover, or anyone with a thirst for pragmatic, how-to knowledge. With this comprehensive edition, you will be armed with one of the most thorough volumes available for dealing with these incredible reptiles, including definitive advice on: Precautions to avoid snake bites. Identifying the symptoms and signs of snake venom poisoning. First-Aid and medical treatments. Recognizing poisonous snakes. Indigenous species to various regions around the world. Sources of Antivenin. Snakes can be among some of the most deadly creatures on the planet. They are also extremely fascinating, and by taking the proper precautions, can be enjoyed and appreciated. From the Monocle Cobra to the Gaboon Viper, learn to fear and respect these incredible reptiles.

Veterinary Toxicology for Australia and New Zealand
Author : Rosalind Dalefield
Publisher : Elsevier
Release Date : 2017-06-23
ISBN 10 : 0127999124
Pages : 628 pages
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Veterinary Toxicology for Australia and New Zealand is a reference suited to the unique challenges of veterinary practice in Australia and New Zealand. Both streamlined and thorough in its coverage of poisons and treatments for those locations, this focused approach allows readers to quickly find relevant information that is presented in a concise and logical manner that is useful to clinicians. The authors draw upon a wealth of knowledge of the particularities of toxicology in Australia and New Zealand to present readers with the up-to-date information required to efficiently and effectively diagnose and treat their patients. Highlights toxins of specific concern in Australia and New Zealand Structures information in a logical way so that it can be located quickly Offers up-to-date information on current and emerging risks

Neuroparasitology and Tropical Neurology
Author : Oscar H. Del Brutto,Hector H. Garcia
Publisher : Elsevier Inc. Chapters
Release Date : 2013-07-03
ISBN 10 : 012807969X
Pages : 432 pages
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Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.