This book serves as a comprehensive overview of the current scientific knowledge on the health effects of dietary and supplemental antioxidants (such as vitamins C and E). Chapters integrate information from basic research and animal studies, epidemiologic studies, and clinical intervention trials. The popular media has taken great interest in antioxidants, with numerous articles emphasizing their role in preventing disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency symptoms, but also chronic disorders such as heart disease and certain types of cancer. This book, therefore, is not only for scientists and doctors, but also for health writers, journalists, and informed lay people. The text focuses on several human conditions for which there is now good scientific evidence that oxidation is an important etiological component. Specifically, antioxidants may prevent or slow down the progression of: Cancer, Cardiovascular disease, Immune system disorders, Cataracts, Neurological disorders, Degeneration due to the aging process.
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
The recognition of oxidative stress as a major factor in health, aging, and disease has led to a surge in research aimed at uncovering effective countermeasures in the form of antioxidants. Unique in its two-fold protective function, alpha-lipoic acid has drawn unprecedented interest as a coenzyme in mitochondrial energy metabolism and as an antioxidant and cell redox modulator. Mounting data regarding its potential health benefits demands an authoritative, single-source reference to codify current knowledge and guide future research. A state-of-the-science compilation, Lipoic Acid follows the history of this potent coenzyme and the latest discoveries regarding the chemistry, biological action, and significance in energy production, antioxidant activity, and health. The book is divided into three sections: · Section I: Discovery and Molecular Structure reviews the early studies leading to the discovery of alpha-lipoic acid and explains the molecular structure, biosynthesis, and the characterization of lipoic acid and its chemical derivatives. · Section II: Metabolic Aspects describes in detail the human pharmacokinetics of alpha-lipoic acid including the lipoic acid-derived dehydrogenase complexes and their roles in energy metabolism. It also explains antioxidant activity and redox modulation and how lipoic acid induces Phase II detoxification enzymes through activation of Nrf2-dependent gene expression. · Section III Clinical Aspects discusses enzyme deficiency disorders and the effects of lipoic acid on insulin. It defines lipoic acid influence on signaling pathways and AMP-activated kinase, and considers the therapeutic implications for treatment of metabolic syndromes and the improvement of mitochondrial function by lipoic acid supplementation. Contributions from leading international researchers make Lipoic Acid the most comprehensive, up-to-date account of the impact of this potentially key molecule in diminishing the damaging effects of aging and disease.
Antioxidant Food Supplements in Human Health discusses new discoveries in the areas of oxygen and nitric oxide metabolism and pathophysiology, redox regulation and cell signaling, and the identification of natural antioxidants and their mechanisms of action on free radicals and their role in health and disease. An essential resource for researchers, students, and professionals in food science and nutrition, gerontology, physiology, pharmacology, and related areas. Health effects of antioxidant nutrients Nutrients of vitamins C and E, selenium, alpha-lipoic acid, coenzyme Q10, carotenoids, and flavonoids Natural source antioxidants, including pine bark, ginko biloba, wine, herbs,uyaku, and carica papaya
This book provides state-of-the-art discussion of natural antioxidants from dietary sources, their occurrence, health effects, chemistry, and methodologies. The book summarizes data on the occurrence of antioxidative compounds in cereals and legumes, oilseeds, herbs and spices, vegetables, teas, muscle foods, and other commodities. The antioxidant vitamins and enzymes also are thoroughly discussed. The potential beneficial effects of dietary antioxidants, the chemistry of food antioxidants, and methodologies to assess lipid oxidation and antioxidant activity also have been covered.
|Author||: J T Kumpulainen,J T Salonen|
|Release Date||: 1999-01-01|
|ISBN 10||: 1845698401|
|Pages||: 466 pages|
Natural antioxidants and anticarcinogens in nutrition, health and disease represents the most recent information and state-of-the-art knowledge on the role of antioxidative vitamins, carotenoids and flavonoids in ageing, atherosclerosis, and diabetes, as well as the role of natural anticarcinogenic compounds, particularly lignans and isoflavonoids, and cancer prevention. It is highly interdisciplinary, and will be of importance to all scientists working in the medical, biomedical, nutritional and food sciences as well as the academics.
Antioxidants and their mechanisms of action; Food factors as antioxidants; Coronary heart disease; Malignant disease; Other diseases; Indicators of oxidative stress; Consumer issues.
Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. Explores neuronal protection by polyphenol metabolites and their application to medical care Defines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applications Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases
|Author||: Roberta Larson Duyff|
|Publisher||: Houghton Mifflin Harcourt|
|Release Date||: 2017-04-18|
|ISBN 10||: 0544520599|
|Pages||: 816 pages|
The newest edition of the most trusted nutrition bible. Since its first, highly successful edition in 1996, The Academy of Nutrition and Dietetics Complete Food and Nutrition Guide has continually served as the gold-standard resource for advice on healthy eating and active living at every age and stage of life. At once accessible and authoritative, the guide effectively balances a practical focus with the latest scientific information, serving the needs of consumers and health professionals alike. Opting for flexibility over rigid dos and don’ts, it allows readers to personalize their own paths to healthier living through simple strategies. This newly updated Fifth Edition addresses the most current dietary guidelines, consumer concerns, public health needs, and marketplace and lifestyle trends in sections covering Choices for Wellness; Food from Farm to Fork; Know Your Nutrients; Food for Every Age and Stage of Life; and Smart Eating to Prevent and Manage Health Issues.
|Author||: Ralf Henkel,Luna Samanta,Ashok Agarwal|
|Publisher||: Academic Press|
|Release Date||: 2018-08-23|
|ISBN 10||: 0128125675|
|Pages||: 324 pages|
Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches Deals with current approaches to oxidative stress using OMICS platform“/li> Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
|Author||: Chi-Tang Ho,Mou-Tuan Huang|
|Release Date||: 1992|
|ISBN 10||: 9780841224759|
|Pages||: 402 pages|
|Author||: Jose Antonio Morales-Gonzalez|
|Publisher||: BoD – Books on Demand|
|Release Date||: 2013-05-22|
|ISBN 10||: 953511123X|
|Pages||: 514 pages|
This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.