antibiotic resistance

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Antibiotic Resistance
Author : Kateryna Kon,Mahendra Rai
Publisher : Academic Press
Release Date : 2016-06-14
ISBN 10 : 0128036680
Pages : 436 pages
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Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries

Antibiotic Resistance
Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Release Date : 2011-01-10
ISBN 10 : 0309156114
Pages : 496 pages
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Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antibiotics and Antibiotic Resistance in the Environment
Author : Carlos F. Amabile-Cuevas
Publisher : CRC Press
Release Date : 2015-12-30
ISBN 10 : 1315679418
Pages : 136 pages
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The presence of antibiotics, antibiotic resistance genes, and antibiotic resistant bacteria in the environment (i.e., outside of clinical settings, such as antibiotic-treated patients or antibiotic-impregnated locations, such as hospitals) is a cause of growing worldwide concern, as it reveals the extensive impact of antibiotic abuse and other huma

Antibiotic Drug Resistance
Author : José-Luis Capelo-Martínez,Gilberto Igrejas
Publisher : John Wiley & Sons
Release Date : 2019-09-24
ISBN 10 : 1119282527
Pages : 720 pages
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This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Superbugs
Author : William Hall
Publisher : Harvard University Press
Release Date : 2018-04-09
ISBN 10 : 0674985079
Pages : 236 pages
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Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.

Mechanisms of antibiotic resistance
Author : Jun Lin,Kunihiko Nishino,Marilyn C. Roberts,Marcelo Tolmasky,Rustam I. Aminov,Lixin Zhang
Publisher : Frontiers Media SA
Release Date : 2015-06-01
ISBN 10 : 2889195260
Pages : 329 pages
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Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Antimicrobial Resistance in Bacteria of Animal Origin
Author : Frank M. Aarestrup
Publisher : Amer Society for Microbiology
Release Date : 2006-01
ISBN 10 : 9781555813062
Pages : 442 pages
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Antimicrobial Resistance in Bacteria of Animal Origin comprehensively examines the current research on antimicrobial resistance in the main veterinary and zoonotic pathogens, including resistance to disinfectants and metals used in agriculture.

Antibiotic Resistance
Author : Anthony R.M. Coates
Publisher : Springer Science & Business Media
Release Date : 2012-10-23
ISBN 10 : 3642289509
Pages : 192 pages
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This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative organisms. The role of combinations of antibiotics in combating resistance emergence is discussed, particularly in the tuberculosis field, and then the importance of non-multiplying and persistent bacteria which are phenotypically resistant to antibiotics and prolong the duration of therapy of antibiotics which leads to poor compliance and resistance emergence. The role of anti-microbial compounds in textiles is covered, with its potential to exacerbate the spread of resistance. Then, efflux pumps are discussed. The final chapter describes the compounds which are in late stage clinical development, illustrating the paucity of the antibiotic pipeline, especially for Gram-negative bacteria.

Antibiotic Resistance
Author : Susumu Mitsuhashi,L. Rosival,V. Kremery
Publisher : Springer
Release Date : 1981-01-08
ISBN 10 : 9783540103226
Pages : 410 pages
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Proceedings from the International Symposium on Antibiotic Resistance 1979, the fourth volume in the series of material edited from the Smolenice symposium, is a continuation in the tradition of communicating new scientific results on a currently important and interesting problem. It concerns not only human and veterinary medicine and practice, but also such important fields of contemporary biology as molecular biology and genetics. Indeed, in both these disciplines, we have recently noted a strong and dynamic de velopment of scientific knowledge directed toward such outgrowths of the study of plasmids as gene manipulations, transposons, and transposition, as well as the evolution of plasmids in general. Because of a very real global development of resistance to the newest antibiotics, and the active participation of experts from medical science and practice, it was reasonable to separate the medical part of the program from the theoretical one. Consequently, priorities of the fourth symposium were transposons and the transposition of resistance of to antibiotics, with their serious impact on epidemiology, the resistance of Pseudomonas aeruginosa, that is becoming a prominent nosocomial pathogen, the ecology and epidemiology ofR plasmids, and, last though not least, the computer-assisted surveillance of resistance to antibiotics.

Antibiotic Resistance in Aquatic Systems
Author : Satoru Suzuki,Amy Pruden,Marko Virta,Tong Zhang
Publisher : Frontiers Media SA
Release Date : 2017-04-10
ISBN 10 : 2889451313
Pages : 329 pages
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Rivers, lakes and the ocean receive antibiotic resistance genes from human environments. The aquatic environments are a huge reservoir and exchange stage of antibiotic resistance genes.

Antibiotic Development and Resistance
Author : Diarmaid Hughes,Dan I Andersson
Publisher : CRC Press
Release Date : 2001-10-11
ISBN 10 : 1134484925
Pages : 288 pages
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The increasing resistance of bacteria towards all current classes of antibiotics is now a serious health problem in both developed and developing countries. Antibiotic Development and Resistance presents 15 chapters that explore the medical issues raised by this development and review the relevant literature. The book begins by reviewing the global

Antibiotics and Antibiotic Resistance
Author : Ola Sköld
Publisher : John Wiley & Sons
Release Date : 2011-10-07
ISBN 10 : 1118075587
Pages : 224 pages
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This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the problem antibiotics resistance poses for medicinal and drug-related fields, and perhaps trigger more research and discoveries to fight antibiotic resistant strains. Current overviews of the topic are included, along with specific discussions on the individual mechanisms (betalactams, glycopeptides, aminoglycosides, etc) used in various antibacterial agents and explanations of how resistances to those develop. Methods for counteracting resistance development in bacteria are discussed as well.

Antibiotic Resistance
Author : Karl S. Drlica,David S. Perlin
Publisher : FT Press
Release Date : 2010-11-24
ISBN 10 : 9780132117326
Pages : 288 pages
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Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

Antibiotics and Antimicrobial Resistance Genes in the Environment
Author : Muhammad Zaffar Hashmi
Publisher : Elsevier
Release Date : 2019-11-22
ISBN 10 : 0128188839
Pages : 432 pages
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Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches. Summarizes and updates information on antibiotics and AMR/ARGs production and its fate and transport in the environment Includes phytoremediation and bioremediation technologies for environmental management Provides analysis of risk assessment of antibiotic resistance genes to help understand the environmental and socioeconomic impacts of antibiotics and AMR/ARGs

Antibiotic Resistance
Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Release Date : 2008-04-30
ISBN 10 : 0470515368
Pages : 260 pages
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Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a selection unprecedented in the history of evolution. Consequently, society is facing one of its gravest public health problems-the emergence of infectious bacteria with resistance to many, and in some cases all, available antibiotics. This book brings together a multidisciplinary group of experts to discuss this problem. It begins by examining the origins of resistance and goes on to look at how the use of antibiotics in human medicine and farming/agriculture has selected for resistant bacteria. Separate chapters describe the evolution of resistance determinants and how these are spread both within and between bacterial species. Finally, the book contains discussions on strategies for countering the threat of antibiotic resistance. A major re-thinking of our approach to the treatment of infectious diseases is proposed-that antibiotic resistance should be seen as a problem created by the disruption of normal microbial ecology. To restore efficacy to earlier antibiotics, and to maintain the success of new antibiotics that are introduced, we need to use these drugs in a way that ensures an ecological balance that favours the predominance of susceptible bacteria.

Antibiotic Resistance
Author : S. H. Gillespie
Publisher : Springer Science & Business Media
Release Date : 2001
ISBN 10 : 1592590772
Pages : 287 pages
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At a time of rising concern about drug resistance and falling output of new antibacterial compounds, antibiotic research has once again returned to the forefront of medical science. In Antibiotic Resistance: Methods and Protocols, Stephen Gillespie and a panel of leading clinical and diagnostic microbiologists describe a series of detailed molecular and physical methods designed to study the growing problem of antibiotic resistance, as well as facilitate new antibiotic research programs for its effective redress. The techniques range widely from those that provide rapid diagnosis via DNA amplification and phage display, to those for plotting the transmission of resistant organisms and investigating their epidemiology. The methods are readily adaptable to a wide range of resistant bacterial organisms. In order to ensure successful results, each method is described in minute detail and includes tips on avoiding pitfalls. Practical and wide-ranging, Antibiotic Resistance: Methods and Protocols provides a collection of indispensable techniques not only for illuminating the basic biology of antimicrobial resistance, but also for developing and implementing new diagnostic and epidemiological tools.

Antibiotic Resistance
Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Release Date : 2011-01-10
ISBN 10 : 0309156114
Pages : 496 pages
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Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antibiotic Resistance
Author : Siouxsie Wiles
Publisher : Bridget Williams Books
Release Date : 2017-04-10
ISBN 10 : 0947518665
Pages : 136 pages
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In ten years’ time, will antibiotics still work? Have we let bacteria get the upper hand in the evolutionary arms race? In the 1920s the discovery of the antibiotic penicillin started a golden age of medicine. However, experts warn that the end of that age may be just a decade away. In this BWB Text, microbiologist Siouxsie Wiles explores the looming crisis of antibiotic resistance and its threat to New Zealand. Wiles concludes that New Zealand must do more to protect the public from a future without antibiotics.

Antimicrobial Resistance in Agriculture
Author : Indranil Samanta,Samiran Bandyopadhyay
Publisher : Academic Press
Release Date : 2019-09-25
ISBN 10 : 0128165235
Pages : 392 pages
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Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment