an evidence based approach to the management of nasopharyngeal cancer

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An Evidence-Based Approach to the Management of Nasopharyngeal Cancer
Author : Baharudin Abdullah,Anusha Balasubramanian,Norhafiza Mat Lazim
Publisher : Academic Press
Release Date : 2020-05-22
ISBN 10 : 0128144041
Pages : 330 pages

An Evidence-Based Approach to the Management of Nasopharyngeal Cancer: From Basic Science to Clinical Presentation and Treatment provides a comprehensive overview with updated management procedures for nasopharyngeal carcinoma. Written by experts on the subject, it is organized in a simple yet comprehensive manner to aid in the understanding of this complex condition. The book discusses several topics related to NPC, including epidemiology, pathophysiology, risk factors and treatment (surgical and non-surgical). Additionally, it discusses key features of clinical presentation of NPC, recent advances and promising new therapies. This will be a valuable source for clinicians, graduate students, oncologists and several members of the biomedical field who are interested in understanding nasopharyngeal cancer in a practical and applicable way. Discusses current trends in surgery, including the use of endoscopy and robotic and navigation technology in the management of NPC Presents a summary with diagrams and workflows at the end of every chapter as a quick reference guide Encompasses colorful figures of pathology, clinical cases, endoscopic findings, surgical approaches, resection of tumors, brachytherapy and robotic and navigation technology so readers fully comprehend content

Nasopharyngeal Cancer
Author : Jiade J. Lu,Jay S. Cooper,Anne W. M. Lee
Publisher : Springer Science & Business Media
Release Date : 2010-01-13
ISBN 10 : 9783540928102
Pages : 337 pages

Nasopharyngeal Cancer - Multidisciplinary Management provides a comprehensive account of the current state of knowledge on nasopharyngeal cancer and its multidisciplinary management. The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. Subsequently, the various treatment options and combinations in a range of settings are examined in depth. Detailed attention is given to the roles of concurrent, adjuvant, and neoadjuvant chemotherapy and advanced radiotherapy techniques. Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children. This is an important book that will prove essential reading for the radiation oncology community worldwide and meet the need for substantial improvements in knowledge of modern techniques.

An Evidence-based Approach to the Treatment and Care of the Older Adult with Cancer
Author : Diane G. Cope,Anne M. Reb
Publisher : N.A
Release Date : 2006
ISBN 10 :
Pages : 625 pages

This quick and user-friendly guide is your ready reference for information on palliative care.

Evidence-Based Management of Head and Neck Vascular Anomalies
Author : Jonathan A. Perkins,Karthik Balakrishnan
Publisher : Springer
Release Date : 2018-10-15
ISBN 10 : 3319923064
Pages : 316 pages

This text addresses vascular anomalies and the management of these diverse and clinically challenging set of conditions which have significant impact on patient function, quality of life and, in certain cases, survival. The text covers each category and type of vascular anomaly and the unique diagnostic and therapeutic challenges they pose. The chapters will also include fundamental scientific literature pertaining to each specific condition to help clinicians and clinical researchers better assess and manage vascular anomalies of the head and neck. Each vascular condition will be supported with medical photographs and radiographic images, summaries of diagnostic and therapeutic options, a list of syndromes and genetic mutations known to be associated with each anomaly, case studies, and clinical and research pearls from national and international leaders in the field. Management of Head and Neck Vascular Anomalies: Evidenced-based Assessment will be an invaluable resource for otolaryngologists, plastic surgeons, general and general pediatric surgeons, orthopaedic surgeons, dermatologists, interventional radiologists, residents and fellows in these fields, and researchers with interest in vascular anomalies of the head and neck.

Head and Neck Cancer
Author : Elizabeth C. Ward,Corina J. van As-Brooks
Publisher : Plural Publishing
Release Date : 2014-07-15
ISBN 10 : 1597566594
Pages : 640 pages

Head and Neck Cancer
Author : Eric M. Genden,Mark A. Varvares
Publisher : Thieme
Release Date : 2011-01-01
ISBN 10 : 1588906361
Pages : 256 pages

Designed to synthesize the collective wisdom of a tumor board, the book presents a multidisciplinary, evidence-based approach to the contemporary management of head and neck cancer. Expert authors and contributors provide a balanced literature review that provides the reader with a solid understanding of the fundamental concepts of the disease entity, descriptions of anatomy, physiology, and clinical presentation, discussion of diagnostic workup and the various management techniques.Highlights: Each chapter features the clinical insights of a surgeon, a medical oncologist, and a radiation oncologist Comprehensive coverage of the most important disease sites, including the oral cavity, oropharynx, hypopharynx, larynx, thyroid gland, salivary glands, nasal cavity and paranasal sinus, nasopharynx, and skin Numerous case examples at the end of each chapter aid comprehension of each major malignancy and enable readers to match real life cases to the clinical situations described in the text Practical discussion of managing carcinoma of unknown primary site More than 140 illustrations demonstrate key concepts and surgical techniques The book is invaluable for practitioners, residents, and students in otolaryngology-head and neck surgery, radiation oncology, and medical oncology, as well as for fellows in head and neck surgical oncology and major reconstructive surgery.

Radiation Oncology
Author : Jiade J. Lu,Luther W. Brady
Publisher : Springer Science & Business Media
Release Date : 2008-11-23
ISBN 10 : 9783540773856
Pages : 679 pages

Radiation Oncology: An Evidence-Based Approach (ROEBA) is a reference book designed to enable radiation oncologists, including those in training, to make diagnostic and treatment decisions on the basis of the best available scientific evidence. Ease of use is ensured by a structured, reader-friendly format that offers rapid access to evidence-based recommendations. ROEBA’s orientation is entirely practical, in that the focus is solely on diagnostic/staging and treatment issues. Detailed diagnostic and therapeutic guidelines are provided for multidisciplinary cancer management as well as radiation therapy techniques. The evidence underlying each recommendation is clearly and concisely explained, and the strength of the recommendations and evidence is systemically graded. Furthermore, diagnostic and treatment algorithms are provided for the commonly diagnosed cancers. This ground-breaking text on radiation oncology is an essential tool for physicians in their daily clinical practice.

Nasopharyngeal Carcinoma
Author : Anne W.M. Lee,Maria Li Lung,Wai Tong Ng
Publisher : Academic Press
Release Date : 2019-03-23
ISBN 10 : 012814937X
Pages : 394 pages

Nasopharyngeal Carcinoma: From Etiology to Clinical Practice discusses NPC from basic science, to clinical management through the perspective of members of the Centre for Nasopharyngeal Carcinoma Research in Hong Kong. It encompasses not only the most detailed information about multiple aspects of NPC, but also the modern day research model of scientist-clinician collaboration, focusing on bench-to-bedside approach. Basic science is covered, discussing genetics and genomics in NPC and its epidemiology and the role of Epstein-Barr Virus (EBV). Translational research is also covered, presenting topics such as animal models, plasma EBV DNA, molecular imaging and immunotherapy, amongst other topics. This book is a valuable source for cancer researchers, oncologists, medical oncologists and several members of the biomedical field who are interested in learning more about NPC management from both clinical and research perspectives. Written by members of the Centre for Nasopharyngeal Carcinoma Research Extensively covers various aspects of NPC, including basic science and the clinical advances of both scientists and clinicians Discusses the molecular information gained through laboratory studies to stimulate research on new treatment strategies

Neurologic Complications of Cancer Therapy
Author : Eudocia Quant Lee, MD, MPH,David Schiff, MD,Patrick Y. Wen, MD
Publisher : Demos Medical Publishing
Release Date : 2011-09-28
ISBN 10 : 1617050199
Pages : 200 pages

Neurologic side effects of cancer therapy can inhibit treatment, can be dose-limiting and can diminish quality-of-life. Neurotoxicity related to cancer therapy is a common problem in oncology practice and in clinical neurology. Recognition of neurologic complications of anticancer therapy is necessary due to potential confusion with metastatic disease, paraneoplastic syndromes or comorbid neurologic disorders that do not require reduction or discontinuation of therapy. Neurologic Complications of Cancer Therapy provides comprehensive coverage of the recognition and management of neurologic symptoms related to cancer therapy. The book includes sections on systemic therapy discussed by both agent and adverse event. The section on adverse events is particularly valuable to clinicians, allowing them to consult by symptom in cases where multiple agents have been administered and the source of the complication is uncertain. The systemic therapy section includes coverage of immunologic agents, biologics, and targeted therapies. The book also features sections on the complications of radiation therapy, complications of surgery and high-dose chemotherapy, and stem cell transplantation. Neurologic Complications of Cancer Therapy Features: A widely recognized team of editors Systemic therapy covered by therapeutic agent and by adverse event, enabling a "problem-oriented" approach for the clinician Coverage of newer modalities including immunologic agents, biologics, and targeted therapies Complete sections on complications of radiation therapy, surgery, high-dose chemotherapy, and stem-call transplantion

Evidence-Based Practice of Anesthesiology E-Book
Author : Lee A Fleisher
Publisher : Elsevier Health Sciences
Release Date : 2013-01-15
ISBN 10 : 1455740381
Pages : 612 pages

Make informed clinical decisions with reliable, up-to-date guidance from Evidence-Based Practice of Anesthesia, 3rd Edition! Leading authority Lee A. Fleisher, MD expertly explores the full range of important issues in perioperative management, discussing the available options, examining the relevant research, and presenting practical recommendations. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Make sound, evidence-based decisions on every aspect of patient care: preoperative assessment, monitoring and administration of anesthesia during surgery, postoperative intensive care management, and postoperative pain management. Master the current best practices you need to know for day-to-day practice and oral board review. Confidently navigate the latest issues thanks to new chapters on optimal airway management in GI endoscopy, the role of Ketamine for perioperative management, fast-track surgery, and hypothermia after intraoperative cardiac arrest, plus many other vital updates. Efficiently translate evidence into practice with numerous quick-reference tables and short, well-organized chapters that promote fast and effective decision making. Get practical decision-making tools you can use in both routine care and complicated or special situations.

Evidence-Based Clinical Practice in Otolaryngology, An Issue of Otolaryngologic Clinics - E-Book
Author : Timothy L. Smith
Publisher : Elsevier Health Sciences
Release Date : 2012-10-08
ISBN 10 : 1455747440
Pages : 240 pages

The concept of Evidence Based Medicine (EBM) has flourished in recent years and it seems that clinicians, more than ever, crave evidence from the medical literature to inform their clinical care decision making. While it is heartening that great volumes of evidence may exist, it is a daunting task to assimilate, critically review, prioritize, grade, and operationalize this crucial information. This volume of Otolaryngologic Clinics attempts to do just that. This book examines Evidence Based Practices on topics of critical importance to otolaryngologists-head and neck surgeons. The evidence has been gathered and is presented by leaders in their respective fields. Topics cover evidence-based practice of: Management of Vertigo, Management of Adult Sensory Neural Hearing Loss, Cochlear Implantation, Reflux in Sinusitus, Balloon Dilation in Otolaryngology, Postoperative Care in Endoscopic Sinus Surgery, Functional Rhinoplasty, Sublingual Immunotherapy for Allergic Rhinitis, Adult Obstructive Sleep Apnea, Pediatric Obstructive Sleep Apnea, Pediatric Tonsillectomy, Management of Vocal Cord Paralysis, Management of Hoarseness, Endoscopic Skull Base Resection for Malignancy, Management of Glottic Cancer, Management of Thyroid Cancer, and Management of N0 Neck.

Orthopedic Rehabilitation Clinical Advisor - E-Book
Author : Derrick Sueki,Jacklyn Brechter
Publisher : Elsevier Health Sciences
Release Date : 2009-10-27
ISBN 10 : 0323072526
Pages : 984 pages

Access the information you need to confidently diagnose and treat musculoskeletal disorders at a glance! With a "5-books-in-1" approach, this essential clinical reference provides up-to-date diagnostic and therapeutic information on over 200 orthopedic conditions in a bulleted, quick-reference format ideal for both students and practitioners. Content is written entirely by orthopedic physical therapists and is logically organized to promote accurate, efficient differential diagnosis and intervention. '5-books-in-1' format combines essential content on foundational knowledge, clinical reasoning, orthopedic pathologies, common clinical questions, and pharmacology all in one place for fast, efficient reference. UNIQUE: Expert insight and decision-making strategies for the rehabilitation of musculoskeletal pathologies help you apply sound clinical reasoning to determine the needs of patients with musculoskeletal disorders. UNIQUE: Succinct, bulleted text organizes information consistently for easy access. Clinician-oriented profiles cover 200 orthopedic pathologies with considerations specific to your needs in orthopedic rehabilitation practice. 51 drug class monographs detail indications, dosages, contraindications and physical therapy implications to help you better understand drug interactions and more effectively manage patients.

Evidence-Based Clinical Practice in Otolaryngology
Author : Luke Rudmik
Publisher : Elsevier Health Sciences
Release Date : 2018-01-20
ISBN 10 : 0323544614
Pages : 350 pages

Get a quick, expert overview of the many key facets of today’s otolaryngology practice with this concise, practical resource. Dr. Luke Rudmik and a leading team of experts in the field address high-interest clinical topics in this fast-changing field. Presents an evidence-based, clinical approach to leading topics in otolaryngology. Covers key topics such as management of vertigo; management of adult sensorineural hearing loss; reflux in sinusitis; balloon catheter dilation in rhinology; epistaxis; functional rhinoplasty; sublingual immunotherapy for allergic rhinitis; pediatric obstructive sleep apnea; pediatric tonsillectomy; evaluation and management of unilateral vocal fold paralysis; management of hoarseness; endoscopic skull base resection for malignancy; management of glottic cancer; management of well-differentiated thyroid cancer; and management of the clinical node-negative neck in early stage oral cavity squamous cell carcinoma. Consolidates today’s available information and experience in this challenging area into one convenient resource.

Cancer and its Management
Author : Jeffrey S. Tobias,Daniel Hochhauser
Publisher : John Wiley & Sons
Release Date : 2014-10-03
ISBN 10 : 1118468716
Pages : 624 pages

Now in its seventh edition, this highly-regarded book is designed as an introductory and reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last 6 editions of the book, the aim and scope of the new edition are once again to provide a thorough yet reasonably brief account of the whole field of oncology, focusing on the latest principles of cancer management. The book is already well established, having been first published in 1986 and in continuous print since then. The authors are rightfully proud of their strong legacy of providing carefully revised new editions of this standard and well-received cancer text for audiences in the UK and abroad. Oncology is a very rapidly changing speciality, with many new treatments and even treatment modalities coming on stream with bewildering speed. Besides a thorough general updating of the text, figures, and tables, the new seventh edition adds a new chapter on Molecular Targeted Therapy, making the book 30 chapters in total. This accessible and practical resource is invaluable to trainees and specialists alike in oncology, palliative care and general medicine, as well as specialist nurses, general practitioners, medical students, and professions allied to medicine.

Complications in Head and Neck Surgery E-Book
Author : David Eisele,Richard V. Smith
Publisher : Elsevier Health Sciences
Release Date : 2008-10-31
ISBN 10 : 1437719635
Pages : 848 pages

Effectively avoiding, recognizing, and managing complications is integral to your operative success. Let a multidisciplinary team of experts in otolaryngology, plastic surgery, oral and maxillofacial surgery, and general surgery guide you through the full range of complications associated with every type of head and neck procedure . . . so you will be equipped to produce the most favorable outcomes for even the most challenging cases! Expert, comprehensive, multidisciplinary coverage of head and neck complications helps you to safely incorporate new surgical techniques into your practice. An emphasis on complication prevention and recognition assists you in avoiding the "complication cascade." Coverage of both acute and long-term care of patients with head and neck complications prepares you to make effective choices in both instances. A new "Quality of Life" section examines the controversies that often surround selecting one procedure over another, illuminating why certain procedures aren't always best for some patients. A new section on complications of facial plastic and reconstructive surgery equips you to perform these techniques with greater confidence. A consistent, practical chapter format helps you focus on key clinical and surgical considerations. A new, more cohesive full-color illustration program richly captures visual nuances of clinical presentation and operative technique. A bonus CD-ROM allows you to use all of the images from the book in electronic presentations.

Head and Neck Cancer Recurrence
Author : Hisham M. Mehanna,K. Kian Ang
Publisher : Thieme
Release Date : 2012-12-12
ISBN 10 : 3131645717
Pages : 316 pages

Despite significant progress in the treatment of head and neck cancer using new techniques, including organ preservation strategies, recurrence still occurs in up to 50% of patients with locally advanced disease. Head and Neck Cancer Recurrence is the first comprehensive, evidence-based reference on this complex condition, providing state-of-the-art strategies for treating and managing recurrence at each site within the head and neck. With this book at hand, specialists will have guidelines for detecting the presence of a tumor, evaluating the extent and likelihood of successful salvage, determining the most effective treatment modalities, and assessing the potential impact on outcome and function. Special features: Brings together all the current evidence and expertise on the epidemiology, risk factors, clinical and imaging evaluation, and management of recurrent head and neck cancer tumors Includes both curative and palliative approaches, and discusses surgical, radiotherapeutic, and chemotherapeutic strategic options Contains substantial contributions by specialists in speech and language therapy, palliative care, psychology, epidemiology, and clinical cancer nursing to provide a holistic, multidisciplinary approach to the management of recurrence of head and neck cancers Brings the decision-making process to life with illustrative case studies that contain patient histories, clinical findings, treatment planning, and documented results The combination of the most recent clinical advances with the latest thinking in the field makes this book an essential resource for all head and neck surgeons, clinical oncologists, radiation oncologists, nurse practitioners, allied health professionals and senior trainees working to improve patient management and outcomes in this challenging arena.

Multidisciplinary Management of Head and Neck Cancer
Author : Robert I. Haddad, MD
Publisher : Demos Medical Publishing
Release Date : 2010-11-23
ISBN 10 : 1617050121
Pages : 288 pages

Head and neck cancer is a very common cancer worldwide with an estimated 500,000 individuals diagnosed each year. In the United States an average of 39,000 new cases are reported each year representing between 3 to 5% of all new cancer cases diagnosed annually. Head and neck cancers are more common in men and in individuals over the age of 50. The treatment of head and neck cancer is extremely challenging and involves insight and expertise from multiple disciplines. Multidisciplinary Management of Head and Neck Cancer is a comprehensive textbook looking at different aspects of head and neck cancer, including the diagnosis, treatment and outcomes for patients with this disease. The chapters written by world-renowned experts cover the entire discipline of head and neck oncology and include discussion of the role of HPV infections, advances in radiotherapy, new surgical techniques, novel agents in thyroid therapy and more. The book is designed to be both practical and comprehensive for the physicians treating this complex disease. Features of Multidisciplinary Management of Head and Neck Cancer include: A chapter on the role of HPV infections in head and neck cancer A chapter on new advances in radiotherapy for head and neck cancer, including review IMRT, new standards and potential pitfalls Detailed discussion of the role of chemotherapy in head and neck cancer, including commonly used drugs and how to combine them with radiotherapy to improve patient outcomes Detailed discussion on incorporating novel agents with radiotherapy Detailed discussion of novel therapeutics in head and neck cancer, including new drugs and biologics

Clinical Pathways in Neuro-Ophthalmology
Author : Stacy V. Smith,Andrew G. Lee,Paul W. Brazis
Publisher : Thieme
Release Date : 2018-08-16
ISBN 10 : 1626232865
Pages : 316 pages

It is paramount for clinicians to understand the distinguishing signs and symptoms among many different local and systemic neuro-ophthalmic disorders in order to provide the most efficacious evaluations and treatments. Clinical Pathways in Neuro-Ophthalmology: An Evidence-Based Approach, Third Edition reflects the authors' extensive training and experience in the field of neuro-ophthalmology, as well as updates in the field. Stacy Smith, Andrew Lee, Paul Brazis, and an impressive group of contributors have written an unsurpassed learning tool on how to manage patients with known or presumed neuro-ophthalmologic conditions, in the most logical, straightforward, and cost-effective manner. The authors share significant clinical pearls and knowledge throughout 20 chapters. The book lays a solid foundation on the management of neurologic eye disorders including symptoms, ophthalmologic testing, diagnosis, and treatment. Among the discussed disorders are anterior and retrobulbar optic neuropathies, disorders of ocular motility and alignment, lid abnormalities, and anisocoria. Insights are provided on key topics including the use of office examinations, laboratory tests, and neuroimaging studies to make an ophthalmologic diagnosis; and ophthalmologic therapy to treat eye movement disorders such as nystagmus. Key Highlights Unique graphic algorithms help clinicians differentiate conditions with frequently overlapping clinical manifestations The evaluation and treatment of various neuro-ophthalmologic processes, stratified by four classes of evidence and four levels of clinical recommendation A basic set of references for each subject enables readers to expand knowledge High quality four-color clinical images enhance learning This book is essential reading for neuro-ophthalmologists, ophthalmologists, neurologists, and residents and fellows in these fields of medicine.

Head and Neck Imaging E-Book
Author : Peter M. Som,Hugh D. Curtin
Publisher : Elsevier Health Sciences
Release Date : 2011-04-12
ISBN 10 : 0323087922
Pages : 3080 pages

Head and Neck Imaging, by Drs. Peter M. Som and Hugh D. Curtin, delivers the encyclopedic and authoritative guidance you’ve come to expect from this book – the expert guidance you need to diagnose the most challenging disorders using today’s most accurate techniques. New state-of-the-art imaging examples throughout help you recognize the imaging presentation of the full range of head and neck disorders using PET, CT, MRI, and ultrasound. Enhanced coverage of the complexities of embryology, anatomy, and physiology, including original color drawings and new color anatomical images from Frank Netter, help you distinguish subtle abnormalities and understand their etiologies. Compare your imaging findings to thousands of crystal-clear examples representing every type of head and neck disorder. Gain an international perspective from global authorities in the field. Find information quickly with a logical organization by anatomic region. Master the latest approaches to image-guided biopsies and treatments. Utilize PET/CT scanning to its fullest potential, including head and neck cancer staging, treatment planning, and follow up to therapy. Visualize head and neck anatomy better than ever before with greatly expanded embryology, physiology and anatomy content, including original drawings and new color anatomical images. Grasp the finer points of head and neck imaging quickly with more images, more detail in the images, and more anatomic atlases with many examples of anatomic variants.

Head and Neck Cancers
Author : Athanassios Argiris, MD, FACP,Robert L. Ferris, MD, PhD, FACS,David I. Rosenthal, MD, FACR, FASTRO
Publisher : Springer Publishing Company
Release Date : 2018-06-28
ISBN 10 : 0826137784
Pages : 550 pages

“Overall, this is an excellent book on an important topic in cancer that medical oncologists, pharmacologists, and nurses, as well as related healthcare professionals, may find very helpful.” Score: 100, 5 Stars, Doody’s Medical Reviews Head and Neck Cancers: Evidence-Based Treatment presents a practical, state-of-the-art resource for any clinical oncologist treating or managing patients with head and neck cancers, including oropharyngeal cancer, cancer of the oral cavity, laryngeal cancer, nasopharyngeal cancer, hypopharyngeal cancer, cancer of the sinuses and the skull base, salivary gland cancer, and neck lymphadenopathy. Section 1 of the book covers the most pertinent details on the epidemiology, biology, diagnosis and staging of the disease including topics such as the genomic landscape of squamous cell carcinoma of the head and neck and novel imaging modalities. Section 2 discusses the evidence-based treatment modalities for conventional and novel chemotherapy regimens, the evidence behind emerging radiation therapy techniques and the minimally invasive surgical advances changing the landscape of care. The chapters in Section 3 are dedicated to site-specific management, including management guidelines, tables with FDA-approved therapies and relevant ongoing clinical trials as well as instructive clinical cases with important discussion on outcomes and follow up care. Finally, Section 4 focuses on recurrent and metastatic disease and Section 5 provides the essentials on supportive care, including managing the elderly, managing patients suffering from dysphagia and oral complications, and must-know details of quality of life assessment and patient-reported outcomes. Emphasizing the practice-changing techniques and the latest evidence-based treatment advances including targeted therapies, immunotherapy, transoral robotic surgery, and radiation therapy precision, this comprehensive yet accessible textbook is indispensable for any clinical oncologist of each discipline wanting a balanced and evidence-based reference on managing patients with head and neck malignancies. Key Features: Includes didactic clinical cases for each type of head and neck cancer Numerous tables highlight FDA approved therapies and ongoing clinical trials Provides evidence-based recommendations for treating head and neck cancers at each stage of the disease with conventional and novel treatment strategies Covers strategies for managing acute and late complications to treatment